Dear volunteers,
First of all, please excuse me because I wanted to send this message a week ago, but I was not able to do so. As you have seen these days, just like last year, we are entering the summer period, and the rate of sending simulations will be affected. We hope that it does not stop completely, but the sent tasks will be reduced.

I take this opportunity to update the results of the last months: you have been optimizing one of the most used human ventricle models: the O'Hara and Rudy model. We have tested several optimization configurations and have obtained a new adjustment for the model that improves its behavior in relation to a large number of markers reported in the scientific literature. There is still a configurations that has not been finished, but we are already beginning to prepare a scientific publication that summarizes our results. As soon as it is finished and published (it is a long process), we will share it with you and explain it.

In the coming months we will begin to optimize a version of this widely used model, which is the basis of a new model we are developing to study heart failure. We will take advantage of this change in model to automate some things, so the slow pace of summer may be a little longer at the beginning of the school year, but with the objective that the pace will not slow down afterwards.

Thank you all very much for your understanding, and this afternoon, new tasks.

Best regards,
Jesus.

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Estimados voluntarios:
En primer lugar, disculpadme porque este mensaje quería haberlo mandado hace una semana, y no pude hacerlo. Como habéis comprobado estos días, al igual que el año pasado, entramos en el período estival, y el ritmo de envío de simulaciones se verá afectado. Esperemos que no se detenga del todo pero se reducirán las tareas que enviaremos.

Aprovecho para actualizaros que en los últimos meses, habéis estado optimizando uno de los modelos de ventrículo humano más utilizados: el modelo de O'Hara y Rudy. Hemos probado varias configuraciones de la optimización y hemos obtenido un nuevo ajuste del modelo que mejora el comportamiento del mismo con relación a una gran cantidad de marcadores reportados en la literatura científica. Queda un poco para que termine una de las configuraciones, pero estamos ya comenzando a preparar una publicación científica que resuma nuestros resultados. Tan pronto como esté terminada y publicada (es un proceso largo), os la compartiremos y explicaremos.

En los próximos meses comenzaremos a optimizar una versión de este modelo que se usa mucho y que es la base de un nuevo modelo que estamos desarrollando para estudiar la insuficiencia cardiaca. Aprovecharemos este cambio de modelo para automatizar algunas cosas, así que igual el ritmo lento de verano se alarga un poco al comienzo de curso, pero con la idea de que después no baje el ritmo.

Muchas gracias a todos por la comprensión, y esta tarde, tareas nuevas.

Un saludo,
Jesús.

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Jesús Carro
Universidad San Jorge
@InSilicoHeart

After processing the remaining tasks and evaluating them, the configuration that was left to be completed has already been completed, so the stop of sending new tasks begins now.

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Tras procesar las tareas que quedaban pendientes y evaluarlas, la configuración que faltaba por terminar ya ha terminado, por lo que la parada de tareas comienza ya.

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Jesús Carro
Universidad San Jorge
@InSilicoHeart

Thanks for the update.

Thank you very much for update Jesús!

It's exciting to see our crunching helps science!

Hope to see new experiments and tasks soon!

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I crunch for Ukraine

Is it possible to startup a new dataset to continue on current project or new project while old is reviewed?

Yes, it is possible. We are preparing new simulations while we are reviewing and writing the paper of the old ones.

Best,
Jesús.

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Jesús Carro
Universidad San Jorge
@InSilicoHeart

When will new simulations be released to run on people's computers?

There is no date yet. We will let you know as soon as we have an estimate of when this might be.

Best,
Jesús.

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Jesús Carro
Universidad San Jorge
@InSilicoHeart

Any idea when DENIS is resuming sending out work?

That would be nice information to have. Just a hint: Days, Weeks, Months, Season?

That would be nice information to have. Just a hint: Days, Weeks, Months, Season?

In spite of all the credit I have obtained in the distant past, my recent past has been so low that my averqge credit is about as low as I can get..

 	2,078,354 	1 	6 Mar 2023

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I see RAC 2 from while looking at your post profile link.

I see RAC 2 from while looking at your post profile link.

It depends on where you look. I get 1 and 1,76 depending where I look. 1.76 is what my machine thinks.
But in any case, I have received no work in ages.

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Hi!
The new tasks will take on the order of months to arrive. I hope it will be one, but you never know. I plan not to change seasons without sending tasks again.

Best,
Jesús.

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Jesús Carro
Universidad San Jorge
@InSilicoHeart

I was being somewhat humorous when I mentioned seasons.

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Hi Jesús,

Do you have any updates about when next crunch work will be available?

Thank you!

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I crunch for Ukraine

Well we changed seasons with no new work.
So maybe by the new year or Valentines?
Heart work during the lovers heart month?

We haven't changed seasons yet since I said so 😅. October and November are in the same season, and I hope that autumn doesn't end without sending simulations. If nothing goes wrong, in 2 or 3 weeks we should restart sending work.

Best,
Jesús.

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Jesús Carro
Universidad San Jorge
@InSilicoHeart