𝕏

Task 55926984

Name HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pieske_333-conf_577_0
Workunit 26558949
Created 3 Jul 2024, 14:23:06 UTC
Sent 3 Jul 2024, 15:49:38 UTC
Report deadline 6 Jul 2024, 15:49:38 UTC
Received 4 Jul 2024, 21:40:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 2 min 2 sec
CPU time 1 hours 22 min 26 sec
Validate state Valid
Credit 45.35
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.14 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pieske_333-conf_577.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pieske_333-conf_577_0_r214961744_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pieske_333-conf_577_0_r214961744_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.082626
     * GNaL_b in INaL: 0.005559
     * Gto_b in Ito: 0.082320
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031570
     * GKs_b in IKs: 0.001899
     * GK1_b in IK1: 0.160835
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.383481
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035338
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8701108, states[0] = 9.677424, states[40]= 0.007367
Saving checkpoint... 
Iteration: 16643113, states[0] = -87.755165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24722754, states[0] = -12.804832, states[40]= 0.002492
Saving checkpoint... 
Iteration: 32389360, states[0] = -13.853017, states[40]= 0.002272
Saving checkpoint... 
Iteration: 40599255, states[0] = -78.641754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49787551, states[0] = -87.665904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58359917, states[0] = 11.771151, states[40]= 0.007890
Saving checkpoint... 
Iteration: 66456167, states[0] = -87.695048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74721590, states[0] = -18.619655, states[40]= 0.001441
Saving checkpoint... 
Iteration: 82215132, states[0] = -10.622720, states[40]= 0.003111
Saving checkpoint... 
Iteration: 90293996, states[0] = -87.730581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98417882, states[0] = -64.178010, states[40]= 0.000004
Saving checkpoint... 
Iteration: 107363580, states[0] = 5.649579, states[40]= 0.007006
Saving checkpoint... 
Iteration: 116382953, states[0] = -17.096039, states[40]= 0.001670
Saving checkpoint... 
Iteration: 124315386, states[0] = -87.816588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132343958, states[0] = 16.738872, states[40]= 0.009505
Saving checkpoint... 
Iteration: 140580400, states[0] = -64.348889, states[40]= 0.000004
Saving checkpoint... 
Iteration: 149157504, states[0] = 26.540790, states[40]= 0.105990
Saving checkpoint... 
Iteration: 158008996, states[0] = 16.235252, states[40]= 0.009211
Saving checkpoint... 
Iteration: 166597574, states[0] = -87.160157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175436718, states[0] = -87.605529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185717215, states[0] = -28.260003, states[40]= 0.000613
Saving checkpoint... 
Iteration: 194501654, states[0] = 18.129732, states[40]= 0.010759
Saving checkpoint... 
Iteration: 203624975, states[0] = -87.766883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213151499, states[0] = 25.960286, states[40]= 0.099762
Saving checkpoint... 
Iteration: 221352769, states[0] = 5.169817, states[40]= 0.006940
Saving checkpoint... 
Iteration: 230395710, states[0] = -50.914682, states[40]= 0.000033
Saving checkpoint... 
Iteration: 239641261, states[0] = -87.828339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249254949, states[0] = -86.982635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257181010, states[0] = 6.346615, states[40]= 0.007106
Saving checkpoint... 
Iteration: 265576410, states[0] = -78.667768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274125163, states[0] = -87.791246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282595363, states[0] = -87.652043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290803567, states[0] = -87.830379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299412123, states[0] = -85.234899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307351901, states[0] = -1.800585, states[40]= 0.005628
Saving checkpoint... 
Iteration: 315718223, states[0] = -47.687853, states[40]= 0.000054
Saving checkpoint... 
Iteration: 323507028, states[0] = 6.862982, states[40]= 0.007177
Saving checkpoint... 
Iteration: 331932543, states[0] = -87.715101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339390468, states[0] = -59.144398, states[40]= 0.000009
Saving checkpoint... 
Iteration: 347186190, states[0] = -7.492358, states[40]= 0.004026
Saving checkpoint... 
Iteration: 355358090, states[0] = -15.752828, states[40]= 0.001906
Saving checkpoint... 
Iteration: 364385130, states[0] = -54.961259, states[40]= 0.000018
Saving checkpoint... 
Iteration: 373282570, states[0] = -87.793189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381157146, states[0] = 14.074500, states[40]= 0.008398
Saving checkpoint... 
Iteration: 389081795, states[0] = -87.599996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397502655, states[0] = 4.497148, states[40]= 0.006841
Saving checkpoint... 
Iteration: 405578575, states[0] = -87.552300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413842937, states[0] = -3.611108, states[40]= 0.005158
Saving checkpoint... 
Iteration: 421636826, states[0] = 21.869943, states[40]= 0.029736
Saving checkpoint... 
Iteration: 429970435, states[0] = 21.429781, states[40]= 0.024478
Saving checkpoint... 
Iteration: 438161418, states[0] = 7.467541, states[40]= 0.007259
Saving checkpoint... 
Iteration: 446361377, states[0] = -33.216291, states[40]= 0.000371
Saving checkpoint... 
Iteration: 454611464, states[0] = -87.804474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463490291, states[0] = 8.858504, states[40]= 0.007450
Saving checkpoint... 
Iteration: 471476156, states[0] = 17.024153, states[40]= 0.009702
Saving checkpoint... 
Iteration: 479070641, states[0] = -87.528694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487130036, states[0] = 21.966974, states[40]= 0.031084
Saving checkpoint... 
Iteration: 495207162, states[0] = -57.567797, states[40]= 0.000012
Saving checkpoint... 
Iteration: 503402266, states[0] = -87.557281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511937070, states[0] = -87.798311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520657384, states[0] = 4.187307, states[40]= 0.006794
Saving checkpoint... 
Iteration: 529113394, states[0] = -87.830881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536906909, states[0] = -87.685840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544836016, states[0] = -11.367960, states[40]= 0.002910
Saving checkpoint... 
Iteration: 552936498, states[0] = -87.809028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560338050, states[0] = -16.409270, states[40]= 0.001787
Saving checkpoint... 
Iteration: 568808599, states[0] = 11.879701, states[40]= 0.007918
Saving checkpoint... 
Iteration: 577436178, states[0] = -87.815172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586443944, states[0] = 36.337880, states[40]= 0.102166
Saving checkpoint... 
Iteration: 594614902, states[0] = 24.318890, states[40]= 0.075032
Saving checkpoint... 
Iteration: 603137161, states[0] = 12.726734, states[40]= 0.008080
Saving checkpoint... 
Iteration: 612088126, states[0] = -87.780259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620583529, states[0] = -87.767355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629091661, states[0] = -87.797128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637731650, states[0] = -87.695451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646134237, states[0] = 11.855607, states[40]= 0.007914
Saving checkpoint... 
Iteration: 654841107, states[0] = -34.016363, states[40]= 0.000338
Saving checkpoint... 
Iteration: 663542235, states[0] = -85.142316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672196721, states[0] = -69.000336, states[40]= 0.000002
Saving checkpoint... 
Iteration: 680485516, states[0] = -6.647126, states[40]= 0.004280
Saving checkpoint... 
Iteration: 687750374, states[0] = -87.790455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696043140, states[0] = -86.884133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703631289, states[0] = 10.003915, states[40]= 0.007614
Saving checkpoint... 
Iteration: 712024856, states[0] = -66.968316, states[40]= 0.000003
Saving checkpoint... 
Iteration: 719934537, states[0] = 25.466331, states[40]= 0.093443
Saving checkpoint... 
Iteration: 728928265, states[0] = 41.643336, states[40]= 0.036785
Saving checkpoint... 
Iteration: 738386062, states[0] = -87.680376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746710004, states[0] = -87.503138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754939267, states[0] = 20.903726, states[40]= 0.019865
Saving checkpoint... 
Iteration: 762974635, states[0] = -3.552798, states[40]= 0.005174
Saving checkpoint... 
Iteration: 770937048, states[0] = 21.148977, states[40]= 0.021811
Saving checkpoint... 
Iteration: 778988011, states[0] = -23.750901, states[40]= 0.000911
Saving checkpoint... 
Iteration: 787220615, states[0] = -87.715714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795705561, states[0] = -87.524729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804443379, states[0] = 16.750862, states[40]= 0.009513
Saving checkpoint... 
Iteration: 812440914, states[0] = 17.606961, states[40]= 0.010188
Saving checkpoint... 
Iteration: 821139373, states[0] = -8.237099, states[40]= 0.003803
Saving checkpoint... 
Iteration: 829961657, states[0] = 2.602853, states[40]= 0.006538
Saving checkpoint... 
Iteration: 838279390, states[0] = 13.294761, states[40]= 0.008204
Saving checkpoint... 
Iteration: 846669828, states[0] = -54.376481, states[40]= 0.000020
Saving checkpoint... 
Iteration: 855076448, states[0] = -87.818602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863182998, states[0] = -78.166413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871676426, states[0] = -68.414091, states[40]= 0.000002
Saving checkpoint... 
Iteration: 880422283, states[0] = 22.724679, states[40]= 0.043790
Saving checkpoint... 
Iteration: 888209846, states[0] = -87.712400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896330540, states[0] = -52.954200, states[40]= 0.000024
Saving checkpoint... 
Iteration: 904305402, states[0] = -18.903620, states[40]= 0.001404
Saving checkpoint... 
Iteration: 912337807, states[0] = -66.392522, states[40]= 0.000003
Saving checkpoint... 
Iteration: 921125474, states[0] = -3.540284, states[40]= 0.005177
Saving checkpoint... 
Iteration: 929818300, states[0] = -40.488516, states[40]= 0.000150
Saving checkpoint... 
Iteration: 937593405, states[0] = 18.417627, states[40]= 0.011146
Saving checkpoint... 
Iteration: 945276767, states[0] = 7.908314, states[40]= 0.007319
Saving checkpoint... 
Iteration: 954061812, states[0] = -87.804731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962073416, states[0] = 34.536457, states[40]= 0.111605
Saving checkpoint... 
Iteration: 970849776, states[0] = -87.043842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979528852, states[0] = -87.681876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987539611, states[0] = -87.739799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995540973, states[0] = -87.748215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003772100, states[0] = 7.035522, states[40]= 0.007200
Saving checkpoint... 
Iteration: 1012162318, states[0] = -68.316265, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1020020743, states[0] = -87.638896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028003209, states[0] = -82.840656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036176509, states[0] = -87.031388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044202407, states[0] = -87.746749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053343323, states[0] = -87.299694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061337350, states[0] = -86.020106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069263827, states[0] = 8.299548, states[40]= 0.007372
Saving checkpoint... 
Iteration: 1077770912, states[0] = 1.980047, states[40]= 0.006428
Saving checkpoint... 
Iteration: 1086166759, states[0] = -85.224498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095032251, states[0] = -87.752875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103155284, states[0] = -71.848396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111632289, states[0] = -38.892558, states[40]= 0.000185
Saving checkpoint... 
Iteration: 1119948162, states[0] = -15.572834, states[40]= 0.001941
Saving checkpoint... 
Iteration: 1128867001, states[0] = -87.770154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136668664, states[0] = -87.335233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144545590, states[0] = -87.812920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152407080, states[0] = 17.522893, states[40]= 0.010110
Saving checkpoint... 
Iteration: 1160586228, states[0] = 9.565233, states[40]= 0.007550
Saving checkpoint... 
Iteration: 1169702636, states[0] = -87.791332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177988563, states[0] = -83.224821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187014725, states[0] = -87.718796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194912817, states[0] = 11.772391, states[40]= 0.007899
Saving checkpoint... 
Iteration: 1203352045, states[0] = -87.742316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211351169, states[0] = -87.741995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219282370, states[0] = -30.849966, states[40]= 0.000477
Saving checkpoint... 
Iteration: 1228031925, states[0] = -87.796872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237004108, states[0] = -87.688719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244942856, states[0] = -25.792669, states[40]= 0.000764
Saving checkpoint... 
Iteration: 1252887303, states[0] = 21.758870, states[40]= 0.028279
Saving checkpoint... 
Iteration: 1261251134, states[0] = 3.226586, states[40]= 0.006642
Saving checkpoint... 
Iteration: 1270089273, states[0] = -2.135729, states[40]= 0.005545
Saving checkpoint... 
Iteration: 1278135739, states[0] = -68.355080, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1286107221, states[0] = -28.340279, states[40]= 0.000609
Saving checkpoint... 
Iteration: 1294414826, states[0] = 2.931795, states[40]= 0.006593
Saving checkpoint... 
Iteration: 1302670377, states[0] = -87.721124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311283321, states[0] = -44.880820, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1319526000, states[0] = -87.806553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327291223, states[0] = -58.476424, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1335526375, states[0] = -87.812308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343791834, states[0] = -61.900099, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1352307452, states[0] = -85.614148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360681324, states[0] = -87.783935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368535989, states[0] = 25.905497, states[40]= 0.099117
Saving checkpoint... 
Iteration: 1375964407, states[0] = -77.117568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1384172705, states[0] = -87.762327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393316187, states[0] = -87.629451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401105279, states[0] = -41.564505, states[40]= 0.000129
Saving checkpoint... 
Iteration: 1409533954, states[0] = 23.901206, states[40]= 0.067136
Saving checkpoint... 
Iteration: 1417425152, states[0] = -25.150113, states[40]= 0.000808
Saving checkpoint... 
Iteration: 1425344429, states[0] = -87.793121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433040220, states[0] = 20.045099, states[40]= 0.015168
Saving checkpoint... 
Iteration: 1442135602, states[0] = -86.971030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450308497, states[0] = -87.585465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458396531, states[0] = 4.517609, states[40]= 0.006843
Saving checkpoint... 
Iteration: 1465976407, states[0] = -87.642212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474432493, states[0] = -43.244691, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1482513372, states[0] = -87.816886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491254010, states[0] = -29.230139, states[40]= 0.000560
Saving checkpoint... 
Iteration: 1499308267, states[0] = -87.664484, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.706192
 - CaMKt in component CaMK (millimolar): 0.041766
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.017516
 - nass in component intracellular_ions (millimolar): 7.017664
 - ki in component intracellular_ions (millimolar): 144.904760
 - kss in component intracellular_ions (millimolar): 144.904728
 - cansr in component intracellular_ions (millimolar): 1.612015
 - cajsr in component intracellular_ions (millimolar): 1.183347
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.007472
 - hf in component INa (dimensionless): 0.692138
 - hs in component INa (dimensionless): 0.691898
 - j in component INa (dimensionless): 0.681149
 - hsp in component INa (dimensionless): 0.446952
 - jp in component INa (dimensionless): 0.654330
 - mL in component INaL (dimensionless): 0.000194
 - hL in component INaL (dimensionless): 0.292060
 - hLp in component INaL (dimensionless): 0.135590
 - a in component Ito (dimensionless): 0.001013
 - iF in component Ito (dimensionless): 0.999540
 - iS in component Ito (dimensionless): 0.175309
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999540
 - iSp in component Ito (dimensionless): 0.211906
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.802526
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966392
 - jca in component ICaL (dimensionless): 0.947807
 - ffp in component ICaL (dimensionless): 0.999861
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009392
 - xrf in component IKr (dimensionless): 0.029354
 - xrs in component IKr (dimensionless): 0.790787
 - xs1 in component IKs (dimensionless): 0.459907
 - xs2 in component IKs (dimensionless): 0.001206
 - xk1 in component IK1 (dimensionless): 0.996810
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:02:09 (75621): called boinc_finish(0)

</stderr_txt>
]]>


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