𝕏

Task 55865236

Name HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_442_0
Workunit 26529256
Created 3 Jul 2024, 5:19:15 UTC
Sent 3 Jul 2024, 9:07:05 UTC
Report deadline 6 Jul 2024, 18:43:05 UTC
Received 4 Jul 2024, 0:27:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237289
Run time 3 hours 6 min 49 sec
CPU time 3 hours 6 min 33 sec
Validate state Valid
Credit 62.18
Device peak FLOPS 4.27 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_442.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_442_0_r1745070776_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-Pueyo_APDR-conf_442_0_r1745070776_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.704258
     * GNaL_b in INaL: 0.006046
     * Gto_b in Ito: 0.080852
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031616
     * GKs_b in IKs: 0.001912
     * GK1_b in IK1: 0.164202
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.199139
     * GKb_b in IKb: 0.003794
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029797
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11697213, states[0] = -94.918782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23427112, states[0] = -95.071417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35143104, states[0] = -65.939984, states[40]= 0.000002
Saving checkpoint... 
Iteration: 46877081, states[0] = -95.026943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58537163, states[0] = 16.440597, states[40]= 0.005481
Saving checkpoint... 
Iteration: 70238775, states[0] = -94.906228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81927357, states[0] = -95.024600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93654998, states[0] = -80.601215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105424744, states[0] = -95.019442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117141919, states[0] = -61.453885, states[40]= 0.000004
Saving checkpoint... 
Iteration: 128852060, states[0] = -94.992688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140558797, states[0] = 8.323883, states[40]= 0.004914
Saving checkpoint... 
Iteration: 152249194, states[0] = -94.908483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163939438, states[0] = -95.018927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175631303, states[0] = -49.384844, states[40]= 0.000031
Saving checkpoint... 
Iteration: 187363069, states[0] = -94.995651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199073629, states[0] = 1.417328, states[40]= 0.004446
Saving checkpoint... 
Iteration: 210800284, states[0] = -94.959224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222496884, states[0] = -95.027353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234177804, states[0] = -94.745217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245901361, states[0] = -95.008756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257602109, states[0] = -20.822337, states[40]= 0.000925
Saving checkpoint... 
Iteration: 269305084, states[0] = -94.962640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281007528, states[0] = 25.129561, states[40]= 0.093013
Saving checkpoint... 
Iteration: 292711543, states[0] = -94.848160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304433134, states[0] = -95.016708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316161158, states[0] = -89.615714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327890354, states[0] = -95.005246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339622134, states[0] = -39.867822, states[40]= 0.000135
Saving checkpoint... 
Iteration: 351324992, states[0] = -94.975867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363002992, states[0] = 37.747483, states[40]= 0.133842
Saving checkpoint... 
Iteration: 374611850, states[0] = -29.973356, states[40]= 0.000478
Saving checkpoint... 
Iteration: 386197907, states[0] = -94.821528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397998425, states[0] = -95.027281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409737051, states[0] = -94.890377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421509928, states[0] = 23.765129, states[40]= 0.053569
Saving checkpoint... 
Iteration: 433179766, states[0] = -94.765122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444798529, states[0] = -94.957501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456476322, states[0] = -95.024343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468155380, states[0] = -80.407220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479892883, states[0] = -95.005955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491619560, states[0] = -37.340801, states[40]= 0.000193
Saving checkpoint... 
Iteration: 503356123, states[0] = -94.992032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515069393, states[0] = 3.585398, states[40]= 0.004652
Saving checkpoint... 
Iteration: 526815759, states[0] = -94.969904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538457646, states[0] = -95.021321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549968679, states[0] = -95.023131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561579876, states[0] = -2.193806, states[40]= 0.003940
Saving checkpoint... 
Iteration: 573194841, states[0] = -94.815058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584809766, states[0] = -94.965776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596425728, states[0] = -95.014842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608011464, states[0] = 23.307641, states[40]= 0.037754
Saving checkpoint... 
Iteration: 619661962, states[0] = -90.527867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631362281, states[0] = -94.994631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643042945, states[0] = 14.602503, states[40]= 0.005206
Saving checkpoint... 
Iteration: 654764114, states[0] = -94.924982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666526412, states[0] = 20.089374, states[40]= 0.006850
Saving checkpoint... 
Iteration: 678279045, states[0] = -94.940417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690054822, states[0] = 9.994960, states[40]= 0.004969
Saving checkpoint... 
Iteration: 701784149, states[0] = -94.945166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713319269, states[0] = -94.972074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724956557, states[0] = -95.021015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736736629, states[0] = -94.889550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748512845, states[0] = 23.003986, states[40]= 0.028088
Saving checkpoint... 
Iteration: 760234440, states[0] = -94.886275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771991826, states[0] = -95.026243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783755293, states[0] = -94.914602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795402856, states[0] = -95.008773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806998467, states[0] = -95.027029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818617982, states[0] = -35.813270, states[40]= 0.000238
Saving checkpoint... 
Iteration: 830236132, states[0] = -94.888757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841856118, states[0] = -94.991818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853478602, states[0] = -95.024423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865095803, states[0] = -14.913858, states[40]= 0.001484
Saving checkpoint... 
Iteration: 876718841, states[0] = -94.860887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888322376, states[0] = -94.973924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899856519, states[0] = -94.991961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911390063, states[0] = -95.004780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922926293, states[0] = -95.014770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934462111, states[0] = -95.021832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945991288, states[0] = -95.026067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957601223, states[0] = -19.986792, states[40]= 0.000977
Saving checkpoint... 
Iteration: 969329047, states[0] = -94.977883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981051696, states[0] = 11.244719, states[40]= 0.005012
Saving checkpoint... 
Iteration: 992770338, states[0] = -94.931497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004491038, states[0] = -95.025998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016216856, states[0] = -94.857312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027949920, states[0] = -95.019627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039726742, states[0] = -94.874068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051502066, states[0] = 44.510798, states[40]= 0.093231
Saving checkpoint... 
Iteration: 1063257040, states[0] = -94.916541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074984619, states[0] = -95.025117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086754260, states[0] = -94.913144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098529429, states[0] = 19.221020, states[40]= 0.006268
Saving checkpoint... 
Iteration: 1110302539, states[0] = -94.960176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122075607, states[0] = 0.344566, states[40]= 0.004318
Saving checkpoint... 
Iteration: 1133850186, states[0] = -94.988900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145613036, states[0] = -31.094423, states[40]= 0.000425
Saving checkpoint... 
Iteration: 1157374107, states[0] = -94.999029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169136596, states[0] = -55.114372, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1180867473, states[0] = -94.996428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192542873, states[0] = 14.629403, states[40]= 0.005209
Saving checkpoint... 
Iteration: 1204190882, states[0] = -94.806080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215934092, states[0] = -95.016332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227648069, states[0] = -68.929661, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1239387627, states[0] = -95.003773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251073549, states[0] = 1.468505, states[40]= 0.004452
Saving checkpoint... 
Iteration: 1262632090, states[0] = -50.187059, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1274340236, states[0] = -94.983860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286105755, states[0] = -24.239780, states[40]= 0.000752
Saving checkpoint... 
Iteration: 1297834460, states[0] = -94.980745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309620226, states[0] = -37.989459, states[40]= 0.000176
Saving checkpoint... 
Iteration: 1321372643, states[0] = -94.998369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333112798, states[0] = -30.869017, states[40]= 0.000435
Saving checkpoint... 
Iteration: 1344850513, states[0] = -94.988923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356588092, states[0] = -8.121751, states[40]= 0.002741
Saving checkpoint... 
Iteration: 1368332913, states[0] = -94.979841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380064986, states[0] = 5.658349, states[40]= 0.004791
Saving checkpoint... 
Iteration: 1391697316, states[0] = -94.819681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403368976, states[0] = -94.996889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415048598, states[0] = 12.455560, states[40]= 0.005063
Saving checkpoint... 
Iteration: 1426668528, states[0] = -94.116862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438292167, states[0] = -94.951709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449943221, states[0] = -95.018075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461568241, states[0] = 4.142433, states[40]= 0.004694
Saving checkpoint... 
Iteration: 1473323073, states[0] = -94.973988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485099980, states[0] = -18.818914, states[40]= 0.001063
Saving checkpoint... 
Iteration: 1496876569, states[0] = -94.999736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508618000, states[0] = -95.171935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520350168, states[0] = -95.225062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532088356, states[0] = -95.269610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543804461, states[0] = 32.062937, states[40]= 0.127586
Saving checkpoint... 
Iteration: 1555534932, states[0] = 15.459374, states[40]= 0.006564
Saving checkpoint... 
Iteration: 1567253035, states[0] = 6.260078, states[40]= 0.005513
Saving checkpoint... 
Iteration: 1578891228, states[0] = -95.291795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590631586, states[0] = 16.834992, states[40]= 0.006953
Saving checkpoint... 
Iteration: 1602320751, states[0] = 20.996298, states[40]= 0.010581
Saving checkpoint... 
Iteration: 1614048003, states[0] = 8.867878, states[40]= 0.005733
Saving checkpoint... 
Iteration: 1625700092, states[0] = -83.982678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637380075, states[0] = -95.288535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648961222, states[0] = -95.096537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660641208, states[0] = -92.882065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672290662, states[0] = -26.978765, states[40]= 0.000615
Saving checkpoint... 
Iteration: 1683869888, states[0] = -95.280783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695497579, states[0] = -95.184709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1707220948, states[0] = -95.224511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718959629, states[0] = -95.271441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730679641, states[0] = -95.288957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742339667, states[0] = -95.249749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754012999, states[0] = -95.212149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765672999, states[0] = -95.130804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777327758, states[0] = -72.246828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1788906254, states[0] = 27.740804, states[40]= 0.110819
Saving checkpoint... 
Iteration: 1800478277, states[0] = -95.099717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812076701, states[0] = -1.899832, states[40]= 0.004073
Saving checkpoint... 
Iteration: 1823709967, states[0] = -94.877737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835374385, states[0] = -95.022946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847025345, states[0] = 20.190667, states[40]= 0.007094
Saving checkpoint... 
Iteration: 1858646159, states[0] = -67.581100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1870255005, states[0] = -94.922343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881888442, states[0] = -95.009746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893504745, states[0] = 29.802906, states[40]= 0.149704
Saving checkpoint... 
Iteration: 1905222972, states[0] = -94.870422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916829965, states[0] = -94.979978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928402133, states[0] = -95.009368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940022637, states[0] = 21.047283, states[40]= 0.008135
Saving checkpoint... 
Iteration: 1951694544, states[0] = -94.814312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963420940, states[0] = -95.013352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975144880, states[0] = -64.797426, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1986865787, states[0] = -94.995468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998508425, states[0] = 24.473922, states[40]= 0.075957
Saving checkpoint... 
Iteration: 2010238936, states[0] = -94.892199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021969559, states[0] = -95.022394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033701923, states[0] = -94.828593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045366514, states[0] = -94.995495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056948542, states[0] = -95.018706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068486609, states[0] = -95.024732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080092097, states[0] = -11.541861, states[40]= 0.002039
Saving checkpoint... 
Iteration: 2091768219, states[0] = -94.928522, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.902231
 - CaMKt in component CaMK (millimolar): 0.006985
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.583191
 - nass in component intracellular_ions (millimolar): 6.583251
 - ki in component intracellular_ions (millimolar): 145.394241
 - kss in component intracellular_ions (millimolar): 145.394221
 - cansr in component intracellular_ions (millimolar): 1.313295
 - cajsr in component intracellular_ions (millimolar): 1.275272
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880007
 - hs in component INa (dimensionless): 0.880003
 - j in component INa (dimensionless): 0.879974
 - hsp in component INa (dimensionless): 0.725843
 - jp in component INa (dimensionless): 0.879954
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709759
 - hLp in component INaL (dimensionless): 0.451514
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620395
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.694971
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934000
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001610
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335132
 - xs1 in component IKs (dimensionless): 0.243291
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:14:20 (3327): called boinc_finish(0)

</stderr_txt>
]]>


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