𝕏

Task 55831123

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_587_1
Workunit 26513690
Created 2 Jul 2024, 14:35:50 UTC
Sent 3 Jul 2024, 5:22:12 UTC
Report deadline 6 Jul 2024, 5:22:12 UTC
Received 3 Jul 2024, 16:19:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224057
Run time 2 hours 0 min 24 sec
CPU time 1 hours 59 min 8 sec
Validate state Valid
Credit 43.43
Device peak FLOPS 3.39 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.73 MB
Peak swap size 5.34 MB
Peak disk usage 0.63 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_587.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_587_1_r916896507_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_587_1_r916896507_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.375581
     * GNaL_b in INaL: 0.005590
     * Gto_b in Ito: 0.083429
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032254
     * GKs_b in IKs: 0.001971
     * GK1_b in IK1: 0.163937
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.107932
     * GKb_b in IKb: 0.003770
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034329
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 5752785, states[0] = -94.847211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 13876192, states[0] = -94.782357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22018781, states[0] = 26.397942, states[40]= 0.004011
Saving checkpoint... 
Iteration: 30247676, states[0] = -94.419170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38550603, states[0] = -94.695026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46728959, states[0] = -94.698597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54946275, states[0] = -94.689544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62826458, states[0] = -94.687170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70889257, states[0] = -94.682453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79153732, states[0] = -51.831903, states[40]= 0.000070
Saving checkpoint... 
Iteration: 87473336, states[0] = -94.646266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95588765, states[0] = -94.669108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103751396, states[0] = -94.675499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111960176, states[0] = -94.671295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120156899, states[0] = -54.376252, states[40]= 0.000046
Saving checkpoint... 
Iteration: 128506862, states[0] = -94.650423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136863180, states[0] = -94.671183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145042594, states[0] = 21.796799, states[40]= 0.002237
Saving checkpoint... 
Iteration: 153196034, states[0] = -93.898943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161450518, states[0] = -94.629650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169603550, states[0] = -94.664452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177715727, states[0] = -94.670063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185996327, states[0] = -94.666285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194233391, states[0] = -94.308439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202363833, states[0] = -94.570802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210556147, states[0] = -94.657749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218805141, states[0] = -94.669742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226865482, states[0] = -94.668837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235226182, states[0] = -94.281884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243457919, states[0] = -94.631521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251671586, states[0] = -94.667959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259646994, states[0] = -94.666710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267948762, states[0] = -94.666789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276124278, states[0] = -24.539243, states[40]= 0.001324
Saving checkpoint... 
Iteration: 284412365, states[0] = -94.608395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292709389, states[0] = -94.668969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299685061, states[0] = -94.668292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307829281, states[0] = -94.669070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316282473, states[0] = -94.447457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321905466, states[0] = -94.667653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330017280, states[0] = 26.968831, states[40]= 0.005338
Saving checkpoint... 
Iteration: 338296594, states[0] = -94.476507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346557827, states[0] = -94.657442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354825019, states[0] = -94.669020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362879498, states[0] = -94.668110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368509309, states[0] = -94.647686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376710245, states[0] = -94.668800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385066516, states[0] = 13.640978, states[40]= 0.003789
Saving checkpoint... 
Iteration: 393341246, states[0] = -94.545246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401691846, states[0] = -94.668289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410066291, states[0] = 13.729442, states[40]= 0.003775
Saving checkpoint... 
Iteration: 418287217, states[0] = -94.457497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426521393, states[0] = -94.650434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434939691, states[0] = -94.666633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443261835, states[0] = -94.396393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451493038, states[0] = -94.643127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459775155, states[0] = -94.669195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467973726, states[0] = -94.665718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476146639, states[0] = -44.333432, states[40]= 0.000215
Saving checkpoint... 
Iteration: 484539029, states[0] = -94.653948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492859446, states[0] = -94.668240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500934054, states[0] = -94.666647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509002469, states[0] = 40.656582, states[40]= 0.449428
Saving checkpoint... 
Iteration: 517221298, states[0] = -94.262699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525330126, states[0] = -94.530618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533592494, states[0] = -94.661660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541877495, states[0] = -94.667816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550093109, states[0] = 0.819744, states[40]= 0.004452
Saving checkpoint... 
Iteration: 558240590, states[0] = -94.331931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566499545, states[0] = -94.644757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574711241, states[0] = -94.668453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582968677, states[0] = -94.665636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591299333, states[0] = -94.481203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599570202, states[0] = -94.658790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607945668, states[0] = -94.666169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616096968, states[0] = -1.632665, states[40]= 0.004196
Saving checkpoint... 
Iteration: 624399644, states[0] = -94.599363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632723050, states[0] = -94.668557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641191587, states[0] = -93.142762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649351581, states[0] = -94.556797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657765997, states[0] = -94.668837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666020757, states[0] = 26.720543, states[40]= 0.002655
Saving checkpoint... 
Iteration: 674176558, states[0] = -76.304063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 682413969, states[0] = -94.608602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690782725, states[0] = -94.668751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699004234, states[0] = 31.683031, states[40]= 0.317598
Saving checkpoint... 
Iteration: 707342113, states[0] = -94.545721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715730391, states[0] = -94.668507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723839581, states[0] = -94.668138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732113753, states[0] = -15.231583, states[40]= 0.001638
Saving checkpoint... 
Iteration: 740461294, states[0] = -94.631815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748809049, states[0] = -94.668467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756623415, states[0] = -94.664120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764912380, states[0] = -94.666669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773085908, states[0] = 4.867883, states[40]= 0.004567
Saving checkpoint... 
Iteration: 781423162, states[0] = -94.613789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789728763, states[0] = -94.668351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798014609, states[0] = 26.995123, states[40]= 0.011167
Saving checkpoint... 
Iteration: 806248002, states[0] = -94.355347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814482557, states[0] = -94.639247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822829161, states[0] = -94.668102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831044623, states[0] = 21.209493, states[40]= 0.002358
Saving checkpoint... 
Iteration: 839357694, states[0] = -94.563008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847756313, states[0] = -94.668469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855987380, states[0] = -94.664651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864178087, states[0] = -78.603181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 872455053, states[0] = -94.629053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880732054, states[0] = -94.668225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889176705, states[0] = -76.519281, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897517166, states[0] = -94.648607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905808556, states[0] = -94.668184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914120320, states[0] = -21.085725, states[40]= 0.001315
Saving checkpoint... 
Iteration: 922543260, states[0] = -94.653925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930759308, states[0] = -94.668326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939101647, states[0] = -4.957837, states[40]= 0.003628
Saving checkpoint... 
Iteration: 947387963, states[0] = -94.590157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955629948, states[0] = -94.664243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963867831, states[0] = -94.667227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972265417, states[0] = -94.405004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980538379, states[0] = -94.652916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988922619, states[0] = -94.666024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997130456, states[0] = -29.881090, states[40]= 0.001117
Saving checkpoint... 
Iteration: 1005217098, states[0] = -94.245263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013552216, states[0] = -94.655308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021849613, states[0] = -94.667437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030023543, states[0] = 26.370107, states[40]= 0.001976
Saving checkpoint... 
Iteration: 1038196609, states[0] = -93.930637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046526516, states[0] = -94.650413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054679602, states[0] = -94.666687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062795872, states[0] = -94.668000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071000642, states[0] = 39.409728, states[40]= 0.020999
Saving checkpoint... 
Iteration: 1079100676, states[0] = -4.232782, states[40]= 0.003770
Saving checkpoint... 
Iteration: 1087477441, states[0] = -94.637060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095854023, states[0] = -94.667229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104100439, states[0] = -4.058647, states[40]= 0.003803
Saving checkpoint... 
Iteration: 1112272553, states[0] = -94.422860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120546823, states[0] = -94.654195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128691408, states[0] = -94.666943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137052053, states[0] = 18.848247, states[40]= 0.002824
Saving checkpoint... 
Iteration: 1145436011, states[0] = -94.619893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153726549, states[0] = -94.667655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161869557, states[0] = -94.666832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170245960, states[0] = -94.348249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178527976, states[0] = -94.650479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186762786, states[0] = -94.667865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195108587, states[0] = -10.637885, states[40]= 0.002400
Saving checkpoint... 
Iteration: 1200857942, states[0] = -94.666970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209345257, states[0] = -94.548553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217443758, states[0] = -94.623470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225802083, states[0] = -94.667655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233941656, states[0] = -94.665120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242247021, states[0] = -94.351467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250549211, states[0] = -94.654369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258859231, states[0] = -94.666841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267073072, states[0] = 10.946527, states[40]= 0.004158
Saving checkpoint... 
Iteration: 1275437344, states[0] = -94.620312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283667477, states[0] = -94.665782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291898003, states[0] = -94.666021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297666003, states[0] = -94.665691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306051519, states[0] = 19.024344, states[40]= 0.002789
Saving checkpoint... 
Iteration: 1314411893, states[0] = -94.606164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322652416, states[0] = -94.664976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331024654, states[0] = 26.198392, states[40]= 0.001856
Saving checkpoint... 
Iteration: 1339334957, states[0] = -94.535561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347621713, states[0] = -94.662905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355985684, states[0] = -94.663780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364288172, states[0] = -94.457749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370109915, states[0] = -11.802198, states[40]= 0.002171
Saving checkpoint... 
Iteration: 1378435246, states[0] = -94.619085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386798865, states[0] = -94.667385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395036972, states[0] = 23.427000, states[40]= 0.001968
Saving checkpoint... 
Iteration: 1403394311, states[0] = -94.594118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411839738, states[0] = -94.666876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420263435, states[0] = -94.398906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428583388, states[0] = -94.658975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437180436, states[0] = -82.268122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445595939, states[0] = -94.660360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452801869, states[0] = -94.667241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460924508, states[0] = -94.665115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469135814, states[0] = -34.558831, states[40]= 0.000745
Saving checkpoint... 
Iteration: 1477356268, states[0] = -94.560338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485583648, states[0] = -94.658902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493886943, states[0] = -94.665883, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.539077
 - CaMKt in component CaMK (millimolar): 0.004194
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.491628
 - nass in component intracellular_ions (millimolar): 6.491714
 - ki in component intracellular_ions (millimolar): 145.420569
 - kss in component intracellular_ions (millimolar): 145.420553
 - cansr in component intracellular_ions (millimolar): 1.590487
 - cajsr in component intracellular_ions (millimolar): 1.589781
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003753
 - hf in component INa (dimensionless): 0.873561
 - hs in component INa (dimensionless): 0.873562
 - j in component INa (dimensionless): 0.873568
 - hsp in component INa (dimensionless): 0.713842
 - jp in component INa (dimensionless): 0.873571
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719355
 - hLp in component INaL (dimensionless): 0.511590
 - a in component Ito (dimensionless): 0.000639
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.892530
 - ap in component Ito (dimensionless): 0.000325
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.932247
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975837
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002716
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097157
 - xs1 in component IKs (dimensionless): 0.123951
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997431
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:00:02 (16464): called boinc_finish(0)

</stderr_txt>
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