𝕏

Task 55786835

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_333-conf_622_0
Workunit 26491561
Created 2 Jul 2024, 14:15:33 UTC
Sent 3 Jul 2024, 0:02:48 UTC
Report deadline 6 Jul 2024, 0:02:48 UTC
Received 3 Jul 2024, 17:36:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238566
Run time 2 hours 8 min 51 sec
CPU time 2 hours 7 min 38 sec
Validate state Valid
Credit 46.25
Device peak FLOPS 2.46 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.25 MB
Peak swap size 6.36 MB
Peak disk usage 0.12 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_333-conf_622.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_333-conf_622_0_r116458103_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_333-conf_622_0_r116458103_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.031896
     * GNaL_b in INaL: 0.005706
     * Gto_b in Ito: 0.085899
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032077
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.164307
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.097550
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032426
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 5933086, states[0] = -48.873730, states[40]= 0.000137
Saving checkpoint... 
Iteration: 15184848, states[0] = 29.049841, states[40]= 0.001860
Saving checkpoint... 
Iteration: 23965866, states[0] = -84.093340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 32611990, states[0] = -65.109985, states[40]= 0.000021
Saving checkpoint... 
Iteration: 41243399, states[0] = -19.250143, states[40]= 0.000336
Saving checkpoint... 
Iteration: 49965066, states[0] = -84.445797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 58724088, states[0] = 2.281356, states[40]= 0.000194
Saving checkpoint... 
Iteration: 67453664, states[0] = -82.317913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 76203026, states[0] = 16.687523, states[40]= 0.000009
Saving checkpoint... 
Iteration: 84920829, states[0] = -41.700092, states[40]= 0.000172
Saving checkpoint... 
Iteration: 93653334, states[0] = -84.994719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102398503, states[0] = -13.153392, states[40]= 0.000286
Saving checkpoint... 
Iteration: 111507338, states[0] = 29.048317, states[40]= 0.002887
Saving checkpoint... 
Iteration: 120194818, states[0] = 18.928995, states[40]= 0.000005
Saving checkpoint... 
Iteration: 128862530, states[0] = 17.751235, states[40]= 0.000006
Saving checkpoint... 
Iteration: 137465195, states[0] = -84.786905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146463870, states[0] = -84.779813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155222584, states[0] = -7.674661, states[40]= 0.000300
Saving checkpoint... 
Iteration: 164220186, states[0] = -5.701250, states[40]= 0.000290
Saving checkpoint... 
Iteration: 172998960, states[0] = 29.373694, states[40]= 0.006535
Saving checkpoint... 
Iteration: 182197168, states[0] = 13.404954, states[40]= 0.000018
Saving checkpoint... 
Iteration: 191334335, states[0] = 28.624287, states[40]= 0.001579
Saving checkpoint... 
Iteration: 200131464, states[0] = -84.868823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208882828, states[0] = -6.286216, states[40]= 0.000294
Saving checkpoint... 
Iteration: 217543171, states[0] = 0.091896, states[40]= 0.000201
Saving checkpoint... 
Iteration: 226247079, states[0] = -51.503913, states[40]= 0.000072
Saving checkpoint... 
Iteration: 235456585, states[0] = -84.801443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 244228065, states[0] = -28.376669, states[40]= 0.000255
Saving checkpoint... 
Iteration: 251687468, states[0] = 15.250836, states[40]= 0.000011
Saving checkpoint... 
Iteration: 260425346, states[0] = -73.196094, states[40]= 0.000006
Saving checkpoint... 
Iteration: 269387952, states[0] = -22.346090, states[40]= 0.000235
Saving checkpoint... 
Iteration: 278243560, states[0] = -53.749511, states[40]= 0.000057
Saving checkpoint... 
Iteration: 287177179, states[0] = 19.467475, states[40]= 0.000005
Saving checkpoint... 
Iteration: 296399911, states[0] = -42.456351, states[40]= 0.000155
Saving checkpoint... 
Iteration: 305400339, states[0] = -44.206878, states[40]= 0.000135
Saving checkpoint... 
Iteration: 314246989, states[0] = -63.601657, states[40]= 0.000020
Saving checkpoint... 
Iteration: 323084784, states[0] = -71.729671, states[40]= 0.000007
Saving checkpoint... 
Iteration: 331964973, states[0] = -85.012112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 340817427, states[0] = 29.090269, states[40]= 0.003228
Saving checkpoint... 
Iteration: 349743447, states[0] = -63.603398, states[40]= 0.000020
Saving checkpoint... 
Iteration: 358619385, states[0] = -84.905891, states[40]= 0.000001
Saving checkpoint... 
Iteration: 367501697, states[0] = 19.934913, states[40]= 0.000005
Saving checkpoint... 
Iteration: 376412968, states[0] = -71.992863, states[40]= 0.000007
Saving checkpoint... 
Iteration: 385328115, states[0] = 22.842737, states[40]= 0.000015
Saving checkpoint... 
Iteration: 394204774, states[0] = -16.469285, states[40]= 0.000250
Saving checkpoint... 
Iteration: 403340189, states[0] = 14.444577, states[40]= 0.000014
Saving checkpoint... 
Iteration: 412163821, states[0] = 19.980965, states[40]= 0.000005
Saving checkpoint... 
Iteration: 421028800, states[0] = -6.965511, states[40]= 0.000297
Saving checkpoint... 
Iteration: 429971424, states[0] = 29.458721, states[40]= 0.012891
Saving checkpoint... 
Iteration: 438844268, states[0] = 8.992590, states[40]= 0.000051
Saving checkpoint... 
Iteration: 447767927, states[0] = -84.776276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 456699401, states[0] = -17.754274, states[40]= 0.000242
Saving checkpoint... 
Iteration: 465627340, states[0] = 28.040063, states[40]= 0.186442
Saving checkpoint... 
Iteration: 474507466, states[0] = 8.918443, states[40]= 0.000051
Saving checkpoint... 
Iteration: 483373940, states[0] = -32.666768, states[40]= 0.000248
Saving checkpoint... 
Iteration: 492653924, states[0] = 21.055619, states[40]= 0.000006
Saving checkpoint... 
Iteration: 498979251, states[0] = 25.004849, states[40]= 0.000062
Saving checkpoint... 
Iteration: 507784112, states[0] = 34.774723, states[40]= 1.195442
Saving checkpoint... 
Iteration: 516975857, states[0] = 25.770766, states[40]= 0.000109
Saving checkpoint... 
Iteration: 525959322, states[0] = 29.231723, states[40]= 0.032756
Saving checkpoint... 
Iteration: 534699550, states[0] = -29.092242, states[40]= 0.000254
Saving checkpoint... 
Iteration: 543477431, states[0] = 23.665406, states[40]= 0.000025
Saving checkpoint... 
Iteration: 552282538, states[0] = 29.074130, states[40]= 0.507505
Saving checkpoint... 
Iteration: 561018816, states[0] = -12.619039, states[40]= 0.000279
Saving checkpoint... 
Iteration: 569766723, states[0] = -84.913627, states[40]= 0.000001
Saving checkpoint... 
Iteration: 578442280, states[0] = -68.997206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587135514, states[0] = 25.769239, states[40]= 0.000108
Saving checkpoint... 
Iteration: 595918950, states[0] = -84.753761, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604692054, states[0] = -28.403056, states[40]= 0.000254
Saving checkpoint... 
Iteration: 613475191, states[0] = 21.049375, states[40]= 0.000006
Saving checkpoint... 
Iteration: 622260539, states[0] = -84.899471, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630968213, states[0] = 23.913208, states[40]= 0.000029
Saving checkpoint... 
Iteration: 639696981, states[0] = -39.852775, states[40]= 0.000183
Saving checkpoint... 
Iteration: 648287975, states[0] = 28.805785, states[40]= 0.002008
Saving checkpoint... 
Iteration: 657012471, states[0] = -17.404947, states[40]= 0.000244
Saving checkpoint... 
Iteration: 665828251, states[0] = 3.428783, states[40]= 0.000135
Saving checkpoint... 
Iteration: 674564567, states[0] = -84.099118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 683306109, states[0] = 18.343579, states[40]= 0.000005
Saving checkpoint... 
Iteration: 692062059, states[0] = -83.973817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 700754950, states[0] = -84.920549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 709415744, states[0] = -84.860937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 718109696, states[0] = 29.462695, states[40]= 0.011017
Saving checkpoint... 
Iteration: 727335547, states[0] = -12.650570, states[40]= 0.000279
Saving checkpoint... 
Iteration: 736063021, states[0] = -84.506195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744758738, states[0] = -85.003365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753420224, states[0] = -84.959277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 762174114, states[0] = -25.318341, states[40]= 0.000245
Saving checkpoint... 
Iteration: 771225150, states[0] = -84.445472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 780106317, states[0] = 29.193384, states[40]= 0.003890
Saving checkpoint... 
Iteration: 788974638, states[0] = 9.972764, states[40]= 0.000041
Saving checkpoint... 
Iteration: 797889251, states[0] = -84.449943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806720412, states[0] = -84.356344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 815947140, states[0] = 25.213453, states[40]= 0.000071
Saving checkpoint... 
Iteration: 824920903, states[0] = 31.090259, states[40]= 0.726825
Saving checkpoint... 
Iteration: 833813833, states[0] = 1.171854, states[40]= 0.000179
Saving checkpoint... 
Iteration: 842671442, states[0] = -32.775983, states[40]= 0.000247
Saving checkpoint... 
Iteration: 851445939, states[0] = 24.034248, states[40]= 0.000031
Saving checkpoint... 
Iteration: 860349431, states[0] = -50.245536, states[40]= 0.000080
Saving checkpoint... 
Iteration: 869234478, states[0] = -84.867838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 878156773, states[0] = -17.017598, states[40]= 0.000246
Saving checkpoint... 
Iteration: 887042886, states[0] = -84.013193, states[40]= 0.000001
Saving checkpoint... 
Iteration: 895993518, states[0] = -24.534106, states[40]= 0.000242
Saving checkpoint... 
Iteration: 904840582, states[0] = -44.410778, states[40]= 0.000133
Saving checkpoint... 
Iteration: 913686999, states[0] = -63.452431, states[40]= 0.000020
Saving checkpoint... 
Iteration: 922605916, states[0] = 23.813926, states[40]= 0.000027
Saving checkpoint... 
Iteration: 931757206, states[0] = 29.291342, states[40]= 0.004868
Saving checkpoint... 
Iteration: 941080732, states[0] = 28.266857, states[40]= 0.131864
Saving checkpoint... 
Iteration: 950662468, states[0] = -35.246900, states[40]= 0.000230
Saving checkpoint... 
Iteration: 959567045, states[0] = -84.954472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 968411418, states[0] = 28.291253, states[40]= 0.127740
Saving checkpoint... 
Iteration: 977257056, states[0] = 28.242875, states[40]= 0.000976
Saving checkpoint... 
Iteration: 986119405, states[0] = 11.576135, states[40]= 0.000029
Saving checkpoint... 
Iteration: 994990224, states[0] = -33.692336, states[40]= 0.000241
Saving checkpoint... 
Iteration: 1003740807, states[0] = 28.179789, states[40]= 0.148603
Saving checkpoint... 
Iteration: 1012521347, states[0] = -79.158325, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1021355824, states[0] = -81.073985, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1030229714, states[0] = -84.981000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1039074082, states[0] = 29.125978, states[40]= 0.040806
Saving checkpoint... 
Iteration: 1047953185, states[0] = 6.494255, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1056719182, states[0] = -84.896258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065474160, states[0] = -21.066352, states[40]= 0.000232
Saving checkpoint... 
Iteration: 1074281218, states[0] = 8.627318, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1083166102, states[0] = -57.831643, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1092705023, states[0] = -84.760092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1101770931, states[0] = 14.065408, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1110782413, states[0] = 4.646089, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1119583184, states[0] = 25.345015, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1128405895, states[0] = 28.988041, states[40]= 0.002619
Saving checkpoint... 
Iteration: 1137265759, states[0] = 15.146174, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1146061011, states[0] = 28.496123, states[40]= 0.098823
Saving checkpoint... 
Iteration: 1155352569, states[0] = -84.359660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1164210054, states[0] = -84.907723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1172974162, states[0] = -36.027542, states[40]= 0.000222
Saving checkpoint... 
Iteration: 1181746665, states[0] = 23.819209, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1190614637, states[0] = -2.156233, states[40]= 0.000244
Saving checkpoint... 
Iteration: 1199439011, states[0] = 5.683715, states[40]= 0.000094
Saving checkpoint... 
Iteration: 1208234649, states[0] = 28.016822, states[40]= 0.000759
Saving checkpoint... 
Iteration: 1217114588, states[0] = -5.269055, states[40]= 0.000284
Saving checkpoint... 
Iteration: 1226059892, states[0] = 29.427379, states[40]= 0.007612
Saving checkpoint... 
Iteration: 1234944199, states[0] = -2.910236, states[40]= 0.000255
Saving checkpoint... 
Iteration: 1243755296, states[0] = 15.029718, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1252669199, states[0] = -82.942345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1261602461, states[0] = 3.032998, states[40]= 0.000141
Saving checkpoint... 
Iteration: 1270540710, states[0] = 33.519952, states[40]= 0.797512
Saving checkpoint... 
Iteration: 1279479290, states[0] = -57.088748, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1285491098, states[0] = -75.360977, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1294307663, states[0] = -52.384927, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1303083029, states[0] = 14.806928, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1312026068, states[0] = -84.870057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320883197, states[0] = 29.459779, states[40]= 0.009313
Saving checkpoint... 
Iteration: 1329745836, states[0] = 15.592780, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1338608407, states[0] = -13.570695, states[40]= 0.000271
Saving checkpoint... 
Iteration: 1347532997, states[0] = 33.443118, states[40]= 0.779368
Saving checkpoint... 
Iteration: 1356356705, states[0] = -84.886890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1365494215, states[0] = -83.821553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1374371629, states[0] = 28.533697, states[40]= 0.094536
Saving checkpoint... 
Iteration: 1383245118, states[0] = 12.464469, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1392072904, states[0] = 15.617361, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1400875663, states[0] = 29.436119, states[40]= 0.007837
Saving checkpoint... 
Iteration: 1409699218, states[0] = 27.987344, states[40]= 0.213098
Saving checkpoint... 
Iteration: 1418517139, states[0] = -84.882881, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427427437, states[0] = -5.961752, states[40]= 0.000291
Saving checkpoint... 
Iteration: 1436298827, states[0] = -59.692993, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1445234474, states[0] = 15.475339, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1453949460, states[0] = -40.552214, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1462659196, states[0] = -84.548784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1471557005, states[0] = 20.514029, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1480216680, states[0] = 23.898346, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1488958472, states[0] = -57.245932, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1497621759, states[0] = -53.827848, states[40]= 0.000057
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.833175
 - CaMKt in component CaMK (millimolar): 0.217631
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.272198
 - nass in component intracellular_ions (millimolar): 7.272552
 - ki in component intracellular_ions (millimolar): 143.840318
 - kss in component intracellular_ions (millimolar): 143.840282
 - cansr in component intracellular_ions (millimolar): 3.338027
 - cajsr in component intracellular_ions (millimolar): 1.918032
 - cai in component intracellular_ions (millimolar): 0.000162
 - m in component INa (dimensionless): 0.009971
 - hf in component INa (dimensionless): 0.583702
 - hs in component INa (dimensionless): 0.582647
 - j in component INa (dimensionless): 0.553412
 - hsp in component INa (dimensionless): 0.331233
 - jp in component INa (dimensionless): 0.511992
 - mL in component INaL (dimensionless): 0.000336
 - hL in component INaL (dimensionless): 0.183485
 - hLp in component INaL (dimensionless): 0.074868
 - a in component Ito (dimensionless): 0.001229
 - iF in component Ito (dimensionless): 0.999235
 - iS in component Ito (dimensionless): 0.131471
 - ap in component Ito (dimensionless): 0.000626
 - iFp in component Ito (dimensionless): 0.999236
 - iSp in component Ito (dimensionless): 0.147048
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.677741
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.929183
 - jca in component ICaL (dimensionless): 0.911577
 - ffp in component ICaL (dimensionless): 0.998946
 - fcafp in component ICaL (dimensionless): 0.999940
 - nca in component ICaL (dimensionless): 0.042097
 - xrf in component IKr (dimensionless): 0.100227
 - xrs in component IKr (dimensionless): 0.872086
 - xs1 in component IKs (dimensionless): 0.570465
 - xs2 in component IKs (dimensionless): 0.007119
 - xk1 in component IK1 (dimensionless): 0.996739
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
18:36:16 (2628): called boinc_finish(0)

</stderr_txt>
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