𝕏

Task 55749807

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-BASE_ENDO-conf_666_1
Workunit 26473121
Created 2 Jul 2024, 13:56:54 UTC
Sent 2 Jul 2024, 19:14:57 UTC
Report deadline 5 Jul 2024, 19:14:57 UTC
Received 3 Jul 2024, 23:34:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228070
Run time 1 hours 48 min 14 sec
CPU time 1 hours 47 min 42 sec
Validate state Valid
Credit 44.00
Device peak FLOPS 3.85 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.88 MB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-BASE_ENDO-conf_666.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-BASE_ENDO-conf_666_1_r1788669612_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-BASE_ENDO-conf_666_1_r1788669612_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 103.599583
     * GNaL_b in INaL: 0.005861
     * Gto_b in Ito: 0.084044
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031544
     * GKs_b in IKs: 0.001895
     * GK1_b in IK1: 0.160215
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.231639
     * GKb_b in IKb: 0.003835
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032627
     * celltype in environment: 0.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9765663, states[0] = -86.786864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18849279, states[0] = -86.844350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25588851, states[0] = -2.714251, states[40]= 0.003364
Saving checkpoint... 
Iteration: 32266504, states[0] = -86.674729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39980703, states[0] = -86.873394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46652275, states[0] = -68.844187, states[40]= 0.000003
Saving checkpoint... 
Iteration: 56334717, states[0] = -86.771014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65555549, states[0] = 15.555104, states[40]= 0.001924
Saving checkpoint... 
Iteration: 75217861, states[0] = -86.486156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83991841, states[0] = -86.854448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93384143, states[0] = -86.805721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101465758, states[0] = -86.844301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109409152, states[0] = -86.819413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117538812, states[0] = 22.285218, states[40]= 0.001063
Saving checkpoint... 
Iteration: 124395656, states[0] = -86.810042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131444618, states[0] = -86.834227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140697490, states[0] = -86.388326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148588467, states[0] = -1.307344, states[40]= 0.003525
Saving checkpoint... 
Iteration: 155556124, states[0] = 15.452602, states[40]= 0.001996
Saving checkpoint... 
Iteration: 164656574, states[0] = -73.090275, states[40]= 0.000002
Saving checkpoint... 
Iteration: 174677383, states[0] = -86.123191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183802973, states[0] = -86.708587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193310576, states[0] = -86.720698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201680325, states[0] = -86.228342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208264526, states[0] = -86.628370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218235426, states[0] = -86.541787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228358228, states[0] = -86.778274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236975382, states[0] = -86.842197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246874288, states[0] = -86.792031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256194894, states[0] = -86.373669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263584065, states[0] = 1.712131, states[40]= 0.003616
Saving checkpoint... 
Iteration: 270788891, states[0] = -86.682312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279836855, states[0] = -86.755498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287601152, states[0] = -12.734033, states[40]= 0.001787
Saving checkpoint... 
Iteration: 297031164, states[0] = 25.052670, states[40]= 0.000847
Saving checkpoint... 
Iteration: 306759112, states[0] = -86.613572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313582619, states[0] = 2.614798, states[40]= 0.003600
Saving checkpoint... 
Iteration: 322482697, states[0] = -86.843697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331442675, states[0] = -86.830720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339460378, states[0] = -86.837075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348477299, states[0] = -86.842129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358214918, states[0] = -86.463216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368365853, states[0] = -86.784393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377852646, states[0] = -86.772076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386457314, states[0] = -86.835828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395808950, states[0] = -86.716912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402683318, states[0] = -86.284343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410534783, states[0] = 23.795127, states[40]= 0.000933
Saving checkpoint... 
Iteration: 419071551, states[0] = 8.619596, states[40]= 0.003079
Saving checkpoint... 
Iteration: 426297381, states[0] = -86.697384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434689779, states[0] = -86.344093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443432567, states[0] = -86.825979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451862627, states[0] = -86.781154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458991045, states[0] = -86.845123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467336865, states[0] = -86.754604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474968912, states[0] = -86.839121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484185754, states[0] = -86.312538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494305831, states[0] = -86.711454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503917019, states[0] = -86.818304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511863784, states[0] = -86.781903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520343403, states[0] = -86.761760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527287920, states[0] = -86.679162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533967341, states[0] = -86.838369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542616627, states[0] = -28.944015, states[40]= 0.000754
Saving checkpoint... 
Iteration: 550225365, states[0] = -86.503714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558223187, states[0] = -86.495347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566435895, states[0] = -86.826838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575139035, states[0] = -52.191922, states[40]= 0.000046
Saving checkpoint... 
Iteration: 584730133, states[0] = -86.521209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593238268, states[0] = -86.549493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602115078, states[0] = -27.352284, states[40]= 0.000814
Saving checkpoint... 
Iteration: 610196524, states[0] = -86.380034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618615817, states[0] = -28.111850, states[40]= 0.000787
Saving checkpoint... 
Iteration: 625701657, states[0] = -86.404177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633660042, states[0] = -77.567373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642462113, states[0] = -86.836218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649636018, states[0] = -48.972483, states[40]= 0.000075
Saving checkpoint... 
Iteration: 658405279, states[0] = -86.811166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667883932, states[0] = -86.797298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675955415, states[0] = -86.833820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685575092, states[0] = 6.839985, states[40]= 0.003296
Saving checkpoint... 
Iteration: 695045133, states[0] = 19.874044, states[40]= 0.001347
Saving checkpoint... 
Iteration: 703387354, states[0] = -86.799555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710793661, states[0] = -86.689276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719357172, states[0] = -86.774864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728512815, states[0] = 28.515342, states[40]= 0.017440
Saving checkpoint... 
Iteration: 737508962, states[0] = 28.206497, states[40]= 0.064009
Saving checkpoint... 
Iteration: 747265336, states[0] = -86.627668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755646313, states[0] = -60.217501, states[40]= 0.000013
Saving checkpoint... 
Iteration: 762920556, states[0] = -86.818876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771684518, states[0] = -86.297971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781112919, states[0] = -25.124785, states[40]= 0.000877
Saving checkpoint... 
Iteration: 790270229, states[0] = -86.639461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799561096, states[0] = 13.375483, states[40]= 0.002344
Saving checkpoint... 
Iteration: 806115396, states[0] = -27.677901, states[40]= 0.000803
Saving checkpoint... 
Iteration: 813769040, states[0] = -86.636492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821642238, states[0] = -55.661417, states[40]= 0.000027
Saving checkpoint... 
Iteration: 830639035, states[0] = -52.189610, states[40]= 0.000046
Saving checkpoint... 
Iteration: 837748711, states[0] = -86.581448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844937719, states[0] = -86.826299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852253970, states[0] = -86.596747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859148405, states[0] = -62.649803, states[40]= 0.000009
Saving checkpoint... 
Iteration: 867305382, states[0] = -86.708960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875459844, states[0] = -86.834385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882737015, states[0] = -86.543895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889827220, states[0] = -86.740720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898000415, states[0] = -31.772647, states[40]= 0.000032
Saving checkpoint... 
Iteration: 907417646, states[0] = -86.816733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915512834, states[0] = 28.516462, states[40]= 0.017329
Saving checkpoint... 
Iteration: 922032890, states[0] = 24.465094, states[40]= 0.000882
Saving checkpoint... 
Iteration: 929491776, states[0] = -86.843093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938354656, states[0] = -86.771416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945791797, states[0] = -86.684673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952806403, states[0] = -86.710217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961848170, states[0] = -86.764772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969439640, states[0] = -86.826507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976567851, states[0] = 10.377075, states[40]= 0.002827
Saving checkpoint... 
Iteration: 983817792, states[0] = -86.727419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992719750, states[0] = -86.479790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002480835, states[0] = -86.840019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012561917, states[0] = 13.022835, states[40]= 0.002403
Saving checkpoint... 
Iteration: 1022703531, states[0] = -86.410786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032360847, states[0] = -86.776814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041961383, states[0] = -86.834110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049743438, states[0] = -86.564157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057814216, states[0] = -86.721848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065549305, states[0] = 18.225387, states[40]= 0.001570
Saving checkpoint... 
Iteration: 1072132743, states[0] = -45.517311, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1079333137, states[0] = -86.747267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086587893, states[0] = -0.864002, states[40]= 0.003555
Saving checkpoint... 
Iteration: 1094532110, states[0] = 24.734198, states[40]= 0.000865
Saving checkpoint... 
Iteration: 1104680011, states[0] = -86.214852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111979769, states[0] = -86.839222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119489537, states[0] = -86.841671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126502268, states[0] = 37.279267, states[40]= 0.524595
Saving checkpoint... 
Iteration: 1133926522, states[0] = -86.820008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142133499, states[0] = -46.309816, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1151166142, states[0] = -83.409379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158465788, states[0] = -86.834966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167239076, states[0] = -86.549443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176655169, states[0] = -71.154640, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1184494328, states[0] = -86.842492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194436691, states[0] = -86.824231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202255174, states[0] = -86.598481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212116438, states[0] = -28.745438, states[40]= 0.000762
Saving checkpoint... 
Iteration: 1221732264, states[0] = -86.525802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229210202, states[0] = -86.439144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236284828, states[0] = -86.669602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245649771, states[0] = -64.280222, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1252925183, states[0] = -86.818821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260202646, states[0] = -86.405636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269361864, states[0] = -86.776624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277973892, states[0] = -86.836820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287490617, states[0] = -86.841143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295667398, states[0] = -84.109614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305685589, states[0] = -86.306875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314925323, states[0] = -86.818596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323413386, states[0] = -86.812558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330643169, states[0] = -56.680351, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1340576037, states[0] = 6.347449, states[40]= 0.003348
Saving checkpoint... 
Iteration: 1348987114, states[0] = -86.840005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357654246, states[0] = -69.932957, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1367114351, states[0] = -26.598659, states[40]= 0.000837
Saving checkpoint... 
Iteration: 1374977333, states[0] = -86.837330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383037450, states[0] = 22.821042, states[40]= 0.001019
Saving checkpoint... 
Iteration: 1391406901, states[0] = -86.808660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399212525, states[0] = -86.448215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406782804, states[0] = -86.664620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415556928, states[0] = 15.132645, states[40]= 0.002052
Saving checkpoint... 
Iteration: 1423259782, states[0] = -86.610049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429995179, states[0] = -86.841536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438090573, states[0] = -2.871222, states[40]= 0.003391
Saving checkpoint... 
Iteration: 1445097274, states[0] = -8.787523, states[40]= 0.002472
Saving checkpoint... 
Iteration: 1454482095, states[0] = -86.838234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463641652, states[0] = -55.014617, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1470945465, states[0] = -86.826464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477606455, states[0] = -18.347014, states[40]= 0.001135
Saving checkpoint... 
Iteration: 1485517828, states[0] = 28.339238, states[40]= 0.003582
Saving checkpoint... 
Iteration: 1495210459, states[0] = -86.438969, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.718148
 - CaMKt in component CaMK (millimolar): 0.012145
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.608660
 - nass in component intracellular_ions (millimolar): 6.608752
 - ki in component intracellular_ions (millimolar): 145.277550
 - kss in component intracellular_ions (millimolar): 145.277529
 - cansr in component intracellular_ions (millimolar): 1.618360
 - cajsr in component intracellular_ions (millimolar): 1.574534
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.008252
 - hf in component INa (dimensionless): 0.656505
 - hs in component INa (dimensionless): 0.656485
 - j in component INa (dimensionless): 0.656368
 - hsp in component INa (dimensionless): 0.408234
 - jp in component INa (dimensionless): 0.656285
 - mL in component INaL (dimensionless): 0.000235
 - hL in component INaL (dimensionless): 0.459755
 - hLp in component INaL (dimensionless): 0.233145
 - a in component Ito (dimensionless): 0.001082
 - iF in component Ito (dimensionless): 0.999454
 - iS in component Ito (dimensionless): 0.567501
 - ap in component Ito (dimensionless): 0.000552
 - iFp in component Ito (dimensionless): 0.999454
 - iSp in component Ito (dimensionless): 0.616491
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.914941
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999834
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002831
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.462586
 - xs1 in component IKs (dimensionless): 0.272085
 - xs2 in component IKs (dimensionless): 0.000220
 - xk1 in component IK1 (dimensionless): 0.997051
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:34:26 (168333): called boinc_finish(0)

</stderr_txt>
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