𝕏

Task 55576134

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_676_1
Workunit 26389074
Created 1 Jul 2024, 15:21:01 UTC
Sent 1 Jul 2024, 23:16:50 UTC
Report deadline 4 Jul 2024, 23:16:50 UTC
Received 2 Jul 2024, 7:15:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236572
Run time 2 hours 16 min 30 sec
CPU time 1 hours 6 min 17 sec
Validate state Valid
Credit 47.07
Device peak FLOPS 4.75 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.11 MB
Peak swap size 5.31 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_676.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_676_1_r2073326311_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_676_1_r2073326311_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.159968
     * GNaL_b in INaL: 0.005613
     * Gto_b in Ito: 0.085685
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032261
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.166232
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.190826
     * GKb_b in IKb: 0.003808
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035404
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12239636, states[0] = -87.029645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20599357, states[0] = -26.091587, states[40]= 0.000576
Saving checkpoint... 
Iteration: 29642211, states[0] = -74.425545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38025571, states[0] = 19.916963, states[40]= 0.006059
Saving checkpoint... 
Iteration: 46221196, states[0] = -86.889189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54332125, states[0] = -86.996041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62391673, states[0] = -87.014175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70586195, states[0] = -9.240861, states[40]= 0.002450
Saving checkpoint... 
Iteration: 78825393, states[0] = -86.971860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87303914, states[0] = -86.952754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95739143, states[0] = -86.878948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104030339, states[0] = 18.947041, states[40]= 0.005425
Saving checkpoint... 
Iteration: 110717355, states[0] = -86.839365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118821547, states[0] = -86.956558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127609148, states[0] = -31.360953, states[40]= 0.000360
Saving checkpoint... 
Iteration: 135984924, states[0] = -87.007847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144467461, states[0] = -87.004511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153174261, states[0] = -86.737574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161690924, states[0] = -86.782384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170099004, states[0] = -20.922667, states[40]= 0.000853
Saving checkpoint... 
Iteration: 178553888, states[0] = 10.056131, states[40]= 0.004700
Saving checkpoint... 
Iteration: 187306585, states[0] = -86.941039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195800047, states[0] = -86.935753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204278848, states[0] = -86.916549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212694057, states[0] = -86.787499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221014385, states[0] = 22.570815, states[40]= 0.017543
Saving checkpoint... 
Iteration: 229385543, states[0] = -86.982022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238153910, states[0] = -83.295922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246571649, states[0] = 1.726750, states[40]= 0.004321
Saving checkpoint... 
Iteration: 254937645, states[0] = -86.996295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263556215, states[0] = 9.084841, states[40]= 0.004686
Saving checkpoint... 
Iteration: 272015079, states[0] = 22.496164, states[40]= 0.015514
Saving checkpoint... 
Iteration: 280498232, states[0] = -87.006009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288964877, states[0] = -87.001320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297398173, states[0] = -86.985951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305880816, states[0] = -86.980065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314340822, states[0] = -86.962150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322753488, states[0] = -86.887179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331427315, states[0] = -86.993824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339664539, states[0] = -86.529067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348172189, states[0] = -86.720956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356522729, states[0] = 21.162397, states[40]= 0.006953
Saving checkpoint... 
Iteration: 364960943, states[0] = -87.000571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373421851, states[0] = -86.992464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381740612, states[0] = -86.869490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390191098, states[0] = -86.780943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398655189, states[0] = -84.186249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407300965, states[0] = -86.935726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416190344, states[0] = -86.779367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424480528, states[0] = -87.003568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432772191, states[0] = -86.909032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441616546, states[0] = -38.685488, states[40]= 0.000139
Saving checkpoint... 
Iteration: 449906044, states[0] = -86.988170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458277487, states[0] = -86.914518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466664090, states[0] = -86.500923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475002677, states[0] = 34.093530, states[40]= 0.150943
Saving checkpoint... 
Iteration: 483762005, states[0] = -86.897550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492264625, states[0] = -86.900600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501299709, states[0] = -86.934647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509790925, states[0] = -86.927204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518264005, states[0] = -86.899865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526612854, states[0] = -34.911184, states[40]= 0.000234
Saving checkpoint... 
Iteration: 534720779, states[0] = -86.837731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543007649, states[0] = 23.663297, states[40]= 0.081130
Saving checkpoint... 
Iteration: 551161571, states[0] = -86.261524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559257636, states[0] = -86.892220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567782792, states[0] = -86.919668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576051566, states[0] = 11.034188, states[40]= 0.004711
Saving checkpoint... 
Iteration: 584591083, states[0] = -12.904620, states[40]= 0.001748
Saving checkpoint... 
Iteration: 592905540, states[0] = -86.987923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601337928, states[0] = -86.960342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609504995, states[0] = 26.233617, states[40]= 0.144060
Saving checkpoint... 
Iteration: 618098130, states[0] = -19.975413, states[40]= 0.000917
Saving checkpoint... 
Iteration: 626886433, states[0] = -86.981821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635184711, states[0] = -86.767282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643345175, states[0] = -86.964198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651588868, states[0] = -10.784589, states[40]= 0.002132
Saving checkpoint... 
Iteration: 660417502, states[0] = -86.991154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668831718, states[0] = -86.956739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677364060, states[0] = -86.973104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685544659, states[0] = 13.812475, states[40]= 0.004768
Saving checkpoint... 
Iteration: 693749996, states[0] = -86.882332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702190572, states[0] = -86.779632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710479708, states[0] = -87.003249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718685526, states[0] = -86.769000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726775875, states[0] = -86.912682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735351979, states[0] = -86.967540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743932901, states[0] = -86.994803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752579378, states[0] = -3.018084, states[40]= 0.003681
Saving checkpoint... 
Iteration: 761191011, states[0] = -86.780495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769567546, states[0] = 3.880338, states[40]= 0.004494
Saving checkpoint... 
Iteration: 778185017, states[0] = -86.767850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786568010, states[0] = 3.646493, states[40]= 0.004478
Saving checkpoint... 
Iteration: 795198583, states[0] = -86.795839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803390062, states[0] = -86.982937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811742469, states[0] = -86.871860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820131840, states[0] = -55.162647, states[40]= 0.000010
Saving checkpoint... 
Iteration: 828491724, states[0] = -87.004775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837608712, states[0] = -30.705561, states[40]= 0.000386
Saving checkpoint... 
Iteration: 846184045, states[0] = -86.765655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854880205, states[0] = -86.979426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863173230, states[0] = -86.728365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871831138, states[0] = -86.956252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880695650, states[0] = -86.789878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888985183, states[0] = -87.003880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897960176, states[0] = -87.000058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906128918, states[0] = -51.873059, states[40]= 0.000018
Saving checkpoint... 
Iteration: 914697464, states[0] = -86.793510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923487633, states[0] = -87.004181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932141949, states[0] = -67.725212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940574908, states[0] = -0.138338, states[40]= 0.004113
Saving checkpoint... 
Iteration: 949255857, states[0] = -86.889727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957465441, states[0] = -87.000899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963629292, states[0] = -52.289212, states[40]= 0.000017
Saving checkpoint... 
Iteration: 970567823, states[0] = 3.741074, states[40]= 0.004485
Saving checkpoint... 
Iteration: 979149580, states[0] = -78.623082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987669410, states[0] = -86.687838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995981965, states[0] = -87.003364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004382724, states[0] = -86.980240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013355942, states[0] = -86.969226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021789937, states[0] = -86.925962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030702350, states[0] = -86.803142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039473617, states[0] = -87.002125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048358175, states[0] = -86.970231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056940143, states[0] = -86.996145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065476742, states[0] = -87.002571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074250816, states[0] = -86.883147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082913253, states[0] = -86.989733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091470929, states[0] = -87.001677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099784176, states[0] = -86.920609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108276138, states[0] = -86.912681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116853722, states[0] = -86.968107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125446577, states[0] = -86.997398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134109066, states[0] = -31.064220, states[40]= 0.000372
Saving checkpoint... 
Iteration: 1142539120, states[0] = 15.947452, states[40]= 0.004891
Saving checkpoint... 
Iteration: 1151052774, states[0] = 10.535284, states[40]= 0.004706
Saving checkpoint... 
Iteration: 1159281168, states[0] = -86.917677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167588435, states[0] = -10.380317, states[40]= 0.002211
Saving checkpoint... 
Iteration: 1175976362, states[0] = -87.002437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184688762, states[0] = -86.775529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193148340, states[0] = -76.922093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201421161, states[0] = -86.991703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210100917, states[0] = -22.803890, states[40]= 0.000745
Saving checkpoint... 
Iteration: 1218417203, states[0] = -86.990682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227371216, states[0] = -86.975696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235645429, states[0] = -72.696364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243972372, states[0] = -87.001791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252174139, states[0] = -86.733660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260366100, states[0] = -86.973563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268763696, states[0] = -86.898972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276804743, states[0] = -86.938073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284952176, states[0] = -86.998354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293068516, states[0] = 3.389201, states[40]= 0.004460
Saving checkpoint... 
Iteration: 1301044231, states[0] = 13.981002, states[40]= 0.004774
Saving checkpoint... 
Iteration: 1309373780, states[0] = -86.976658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317502177, states[0] = 36.984091, states[40]= 0.129414
Saving checkpoint... 
Iteration: 1325759937, states[0] = -86.894481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333982379, states[0] = -87.003183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342819900, states[0] = -86.948866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351279508, states[0] = -86.915907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359682409, states[0] = -86.761544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368004237, states[0] = 27.904112, states[40]= 0.159421
Saving checkpoint... 
Iteration: 1375999355, states[0] = -87.005314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384245577, states[0] = -86.875833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392355569, states[0] = -86.968784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400645594, states[0] = -72.937531, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408806491, states[0] = -86.939314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417307473, states[0] = -86.940048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425712205, states[0] = -86.821700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434147505, states[0] = -75.728416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442598577, states[0] = -20.428531, states[40]= 0.000885
Saving checkpoint... 
Iteration: 1450659199, states[0] = -85.828736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458874079, states[0] = -86.976669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467252460, states[0] = -86.885019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475696518, states[0] = -86.791205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483779037, states[0] = -86.915345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491857799, states[0] = -86.969745, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.881177
 - CaMKt in component CaMK (millimolar): 0.006714
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.371969
 - nass in component intracellular_ions (millimolar): 6.372027
 - ki in component intracellular_ions (millimolar): 145.612540
 - kss in component intracellular_ions (millimolar): 145.612521
 - cansr in component intracellular_ions (millimolar): 1.290342
 - cajsr in component intracellular_ions (millimolar): 1.252690
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008118
 - hf in component INa (dimensionless): 0.662521
 - hs in component INa (dimensionless): 0.662510
 - j in component INa (dimensionless): 0.662448
 - hsp in component INa (dimensionless): 0.414755
 - jp in component INa (dimensionless): 0.662405
 - mL in component INaL (dimensionless): 0.000227
 - hL in component INaL (dimensionless): 0.467652
 - hLp in component INaL (dimensionless): 0.242311
 - a in component Ito (dimensionless): 0.001071
 - iF in component Ito (dimensionless): 0.999469
 - iS in component Ito (dimensionless): 0.580005
 - ap in component Ito (dimensionless): 0.000546
 - iFp in component Ito (dimensionless): 0.999469
 - iSp in component Ito (dimensionless): 0.635034
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936151
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999896
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001513
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.401387
 - xs1 in component IKs (dimensionless): 0.240524
 - xs2 in component IKs (dimensionless): 0.000216
 - xk1 in component IK1 (dimensionless): 0.997011
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:14:44 (20644): called boinc_finish(0)

</stderr_txt>
]]>


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