𝕏

Task 55455339

Name HuVeMOp_20240630172042907232_ORdGradInc_k_25-Pueyo_APDR-conf_627_0
Workunit 26333627
Created 30 Jun 2024, 15:20:44 UTC
Sent 30 Jun 2024, 15:48:02 UTC
Report deadline 4 Jul 2024, 1:24:02 UTC
Received 1 Jul 2024, 3:58:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 225107
Run time 3 hours 15 min 12 sec
CPU time 3 hours 8 min 23 sec
Validate state Valid
Credit 60.58
Device peak FLOPS 2.43 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 3.54 MB
Peak swap size 1.56 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630172042907232_ORdGradInc_k_25-Pueyo_APDR-conf_627.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630172042907232_ORdGradInc_k_25-Pueyo_APDR-conf_627_0_r753218229_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630172042907232_ORdGradInc_k_25-Pueyo_APDR-conf_627_0_r753218229_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 119.032067
     * GNaL_b in INaL: 0.004422
     * Gto_b in Ito: 0.073532
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030255
     * GKs_b in IKs: 0.001878
     * GK1_b in IK1: 0.149273
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 73.303155
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046703
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8170924, states[0] = -94.937516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20360279, states[0] = -95.094829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32573494, states[0] = -3.107110, states[40]= 0.003889
Saving checkpoint... 
Iteration: 44781653, states[0] = -94.988510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56990051, states[0] = -95.054156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69197468, states[0] = -94.843537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81319295, states[0] = -94.984866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93504088, states[0] = 34.390010, states[40]= 0.127292
Saving checkpoint... 
Iteration: 101448368, states[0] = -95.023927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113460288, states[0] = -95.023396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125442640, states[0] = -95.018419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137464767, states[0] = -95.020997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149659919, states[0] = -92.206900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161854735, states[0] = -94.989110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174028827, states[0] = 18.679319, states[40]= 0.007086
Saving checkpoint... 
Iteration: 186204577, states[0] = -94.834928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198391999, states[0] = -95.001993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210564550, states[0] = 3.789353, states[40]= 0.004777
Saving checkpoint... 
Iteration: 222705727, states[0] = -94.836611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234898183, states[0] = -95.003499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247082403, states[0] = -7.379152, states[40]= 0.002949
Saving checkpoint... 
Iteration: 259291753, states[0] = -94.949098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271505068, states[0] = 30.990672, states[40]= 0.127046
Saving checkpoint... 
Iteration: 283713822, states[0] = -94.851339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294631149, states[0] = -55.601374, states[40]= 0.000009
Saving checkpoint... 
Iteration: 300467451, states[0] = -95.018278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312677200, states[0] = -94.757196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324888246, states[0] = -95.000227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337103303, states[0] = -27.241755, states[40]= 0.000565
Saving checkpoint... 
Iteration: 349308114, states[0] = -94.961382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361525111, states[0] = 19.916796, states[40]= 0.008133
Saving checkpoint... 
Iteration: 373731877, states[0] = -94.881051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385942850, states[0] = -95.013964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398146382, states[0] = -73.738597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410436849, states[0] = -95.012757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422646169, states[0] = -73.435056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434855915, states[0] = -94.987970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447063487, states[0] = 4.318388, states[40]= 0.004821
Saving checkpoint... 
Iteration: 459259685, states[0] = -94.917706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471465710, states[0] = -95.017899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483674122, states[0] = -94.721170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495880763, states[0] = -94.997632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508081437, states[0] = -6.595955, states[40]= 0.003121
Saving checkpoint... 
Iteration: 520280820, states[0] = -94.939367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532485249, states[0] = -95.020652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544672381, states[0] = -94.684938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556858046, states[0] = -94.988835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568972131, states[0] = -95.018824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581166101, states[0] = -94.257930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593357776, states[0] = -94.988702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605555997, states[0] = 7.781932, states[40]= 0.005061
Saving checkpoint... 
Iteration: 617679128, states[0] = -94.769882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629869084, states[0] = -94.993296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641709300, states[0] = -94.842871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653814157, states[0] = -94.965325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666001387, states[0] = 51.829463, states[40]= 0.039291
Saving checkpoint... 
Iteration: 678125716, states[0] = -49.836041, states[40]= 0.000025
Saving checkpoint... 
Iteration: 690318735, states[0] = -94.968250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702513132, states[0] = 23.366056, states[40]= 0.029023
Saving checkpoint... 
Iteration: 714703276, states[0] = -94.831375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726896283, states[0] = -95.002515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739013453, states[0] = 23.266012, states[40]= 0.027343
Saving checkpoint... 
Iteration: 751205780, states[0] = -94.836186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763349398, states[0] = -94.984866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775424420, states[0] = -95.009886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787534452, states[0] = 16.662627, states[40]= 0.006196
Saving checkpoint... 
Iteration: 799722272, states[0] = -94.865614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811909772, states[0] = -95.006262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824101246, states[0] = -25.217835, states[40]= 0.000663
Saving checkpoint... 
Iteration: 836296546, states[0] = -94.952578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848375975, states[0] = -94.995769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860487569, states[0] = -95.020791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872605619, states[0] = -29.520540, states[40]= 0.000457
Saving checkpoint... 
Iteration: 884698675, states[0] = -94.822185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896815106, states[0] = -94.965829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908993946, states[0] = -95.021552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921183510, states[0] = -94.787484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933414927, states[0] = -95.007529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945597449, states[0] = -21.483933, states[40]= 0.000863
Saving checkpoint... 
Iteration: 957709861, states[0] = -94.843758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969903293, states[0] = -95.004427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982091864, states[0] = -16.003323, states[40]= 0.001357
Saving checkpoint... 
Iteration: 994280842, states[0] = -94.939159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006400082, states[0] = -95.003497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018580443, states[0] = -5.820618, states[40]= 0.003289
Saving checkpoint... 
Iteration: 1030766411, states[0] = -94.924849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042783489, states[0] = -94.941536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054966266, states[0] = -95.017706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067075506, states[0] = -2.336053, states[40]= 0.003981
Saving checkpoint... 
Iteration: 1071474133, states[0] = -95.018874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072733600, states[0] = -94.883295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074599745, states[0] = -23.741870, states[40]= 0.000737
Saving checkpoint... 
Iteration: 1079033156, states[0] = 17.146159, states[40]= 0.006356
Saving checkpoint... 
Iteration: 1088832373, states[0] = -94.976081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096037098, states[0] = 15.649938, states[40]= 0.005925
Saving checkpoint... 
Iteration: 1103305214, states[0] = -94.958958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112708170, states[0] = -94.840534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120844301, states[0] = -94.982259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132000920, states[0] = 50.316742, states[40]= 0.016431
Saving checkpoint... 
Iteration: 1143306384, states[0] = -94.959775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155323346, states[0] = -94.970860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167338727, states[0] = -94.979431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179323613, states[0] = -94.971009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191339184, states[0] = -94.979656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203357721, states[0] = -94.988385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215375566, states[0] = -94.995444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227484089, states[0] = -95.020167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239588586, states[0] = -12.855134, states[40]= 0.001833
Saving checkpoint... 
Iteration: 1251702493, states[0] = -94.829587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263837360, states[0] = -94.978674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276027369, states[0] = 19.183571, states[40]= 0.007433
Saving checkpoint... 
Iteration: 1288212586, states[0] = -94.848583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300411444, states[0] = -95.006465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312610001, states[0] = -33.842089, states[40]= 0.000277
Saving checkpoint... 
Iteration: 1324808932, states[0] = -94.961475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336923388, states[0] = -95.009378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349098080, states[0] = -22.104391, states[40]= 0.000826
Saving checkpoint... 
Iteration: 1361276529, states[0] = -94.934929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373476079, states[0] = -95.019007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385678617, states[0] = -94.766547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397870654, states[0] = -94.993530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410071357, states[0] = 0.190656, states[40]= 0.004378
Saving checkpoint... 
Iteration: 1422272253, states[0] = -94.930702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434449975, states[0] = -95.014792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446635671, states[0] = -60.510530, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1458834541, states[0] = -94.977083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471025632, states[0] = 19.751088, states[40]= 0.007949
Saving checkpoint... 
Iteration: 1483228877, states[0] = -94.875906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495342141, states[0] = -94.981010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507484765, states[0] = -95.264330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1519557273, states[0] = 2.816583, states[40]= 0.005215
Saving checkpoint... 
Iteration: 1531622902, states[0] = -67.909900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1543696884, states[0] = -95.194297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555769969, states[0] = -95.296567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567842377, states[0] = 10.766673, states[40]= 0.006214
Saving checkpoint... 
Iteration: 1579915902, states[0] = -60.499934, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1591775627, states[0] = -95.310869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599985854, states[0] = -25.765517, states[40]= 0.000646
Saving checkpoint... 
Iteration: 1612051588, states[0] = -95.050739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624123922, states[0] = -95.258041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636197328, states[0] = -95.329825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648271087, states[0] = -9.470045, states[40]= 0.002792
Saving checkpoint... 
Iteration: 1660340142, states[0] = -93.537475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672404823, states[0] = -95.229271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684482780, states[0] = -95.320587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696559566, states[0] = 0.331891, states[40]= 0.004917
Saving checkpoint... 
Iteration: 1708629831, states[0] = -81.358618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720704892, states[0] = -95.229630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732775135, states[0] = -95.314805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744850871, states[0] = 5.868490, states[40]= 0.005625
Saving checkpoint... 
Iteration: 1756922804, states[0] = -70.096683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1766342254, states[0] = -95.282952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777978663, states[0] = -95.177056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789906158, states[0] = -49.152017, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1801878942, states[0] = -95.067056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813847450, states[0] = -95.033585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825810559, states[0] = -94.998849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837776053, states[0] = -94.960351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849742602, states[0] = -94.914336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861712907, states[0] = -94.862094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873642805, states[0] = -69.720556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1885593043, states[0] = -17.494097, states[40]= 0.001187
Saving checkpoint... 
Iteration: 1897509330, states[0] = 24.977181, states[40]= 0.063038
Saving checkpoint... 
Iteration: 1909478665, states[0] = -95.022275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921478451, states[0] = -95.021301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933430784, states[0] = -95.012314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945385962, states[0] = -94.999790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957375079, states[0] = -94.995678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969363495, states[0] = -94.990968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981329257, states[0] = -94.974281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993308685, states[0] = -94.961233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005265997, states[0] = -94.924107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017213173, states[0] = -94.849401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029174121, states[0] = -94.720541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041129486, states[0] = -53.828161, states[40]= 0.000013
Saving checkpoint... 
Iteration: 2053087566, states[0] = -11.902691, states[40]= 0.002005
Saving checkpoint... 
Iteration: 2065018966, states[0] = 21.728731, states[40]= 0.012444
Saving checkpoint... 
Iteration: 2076984610, states[0] = -95.019818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088912437, states[0] = -95.006325, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.897535
 - CaMKt in component CaMK (millimolar): 0.006390
 - cass in component intracellular_ions (millimolar): 0.000072
 - nai in component intracellular_ions (millimolar): 6.414867
 - nass in component intracellular_ions (millimolar): 6.414925
 - ki in component intracellular_ions (millimolar): 145.571178
 - kss in component intracellular_ions (millimolar): 145.571159
 - cansr in component intracellular_ions (millimolar): 1.280228
 - cajsr in component intracellular_ions (millimolar): 1.243456
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879926
 - hs in component INa (dimensionless): 0.879921
 - j in component INa (dimensionless): 0.879893
 - hsp in component INa (dimensionless): 0.725690
 - jp in component INa (dimensionless): 0.879874
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710676
 - hLp in component INaL (dimensionless): 0.454413
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.626193
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.701761
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938526
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999895
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001496
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339736
 - xs1 in component IKs (dimensionless): 0.231742
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:32:09 (7304): called boinc_finish(0)

</stderr_txt>
]]>


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