𝕏

Task 55402378

Name HuVeMOp_20240630080046859196_ORdGradInc_k_25-Schmidt_575-conf_239_1
Workunit 26307980
Created 30 Jun 2024, 6:01:55 UTC
Sent 30 Jun 2024, 7:47:42 UTC
Report deadline 3 Jul 2024, 7:47:52 UTC
Received 1 Jul 2024, 22:56:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 1 min 18 sec
CPU time 1 hours 29 min 26 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.21 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Schmidt_575-conf_239.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Schmidt_575-conf_239_1_r1789849162_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Schmidt_575-conf_239_1_r1789849162_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.934939
     * GNaL_b in INaL: 0.006560
     * Gto_b in Ito: 0.081924
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031873
     * GKs_b in IKs: 0.001792
     * GK1_b in IK1: 0.154009
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 72.791545
     * GKb_b in IKb: 0.003751
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049812
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9141274, states[0] = -84.693024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17497598, states[0] = -84.703011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 25549051, states[0] = -84.697030, states[40]= 0.000001
Saving checkpoint... 
Iteration: 32853589, states[0] = 0.120127, states[40]= 0.000377
Saving checkpoint... 
Iteration: 41192828, states[0] = -1.356937, states[40]= 0.000391
Saving checkpoint... 
Iteration: 49523132, states[0] = 4.066834, states[40]= 0.000247
Saving checkpoint... 
Iteration: 58157477, states[0] = -3.336825, states[40]= 0.000410
Saving checkpoint... 
Iteration: 65728287, states[0] = -84.254407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74214477, states[0] = 23.243162, states[40]= 0.000011
Saving checkpoint... 
Iteration: 82389527, states[0] = -84.028368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90759465, states[0] = -84.416505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98896464, states[0] = -84.808345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107600089, states[0] = 2.581324, states[40]= 0.000277
Saving checkpoint... 
Iteration: 116330470, states[0] = -84.277775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124361702, states[0] = -83.903485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132477781, states[0] = -84.609544, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141474902, states[0] = 29.565363, states[40]= 0.000316
Saving checkpoint... 
Iteration: 149428997, states[0] = -84.547609, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158129723, states[0] = 30.984161, states[40]= 0.403728
Saving checkpoint... 
Iteration: 166170272, states[0] = -84.804978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 174305296, states[0] = -1.520679, states[40]= 0.000372
Saving checkpoint... 
Iteration: 181937240, states[0] = -84.653515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189943380, states[0] = -84.387838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198453828, states[0] = -0.301294, states[40]= 0.000347
Saving checkpoint... 
Iteration: 206666946, states[0] = -84.673191, states[40]= 0.000001
Saving checkpoint... 
Iteration: 216412803, states[0] = -84.523748, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225768986, states[0] = -2.557927, states[40]= 0.000389
Saving checkpoint... 
Iteration: 233388910, states[0] = -84.600304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 240968639, states[0] = 21.151615, states[40]= 0.000015
Saving checkpoint... 
Iteration: 248679932, states[0] = -84.795993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 256883259, states[0] = -77.169470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 264861048, states[0] = 3.671941, states[40]= 0.000248
Saving checkpoint... 
Iteration: 272122938, states[0] = -79.304010, states[40]= 0.000001
Saving checkpoint... 
Iteration: 279931694, states[0] = -84.391907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287991318, states[0] = -84.462863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296308250, states[0] = -84.299437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304098333, states[0] = -84.509092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 312364252, states[0] = -69.060272, states[40]= 0.000003
Saving checkpoint... 
Iteration: 320887862, states[0] = 24.004824, states[40]= 0.000011
Saving checkpoint... 
Iteration: 328612908, states[0] = -30.446451, states[40]= 0.000078
Saving checkpoint... 
Iteration: 336833928, states[0] = -84.172423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345105832, states[0] = -30.117687, states[40]= 0.000228
Saving checkpoint... 
Iteration: 354068279, states[0] = -83.194442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363694483, states[0] = 30.311251, states[40]= 0.182829
Saving checkpoint... 
Iteration: 371475591, states[0] = 29.318525, states[40]= 0.000249
Saving checkpoint... 
Iteration: 379470546, states[0] = -84.729028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 387518161, states[0] = -84.720688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 396613955, states[0] = -81.706947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404756920, states[0] = -84.678170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 412924564, states[0] = 2.951028, states[40]= 0.000266
Saving checkpoint... 
Iteration: 420797167, states[0] = -84.308774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429000734, states[0] = 17.448417, states[40]= 0.000032
Saving checkpoint... 
Iteration: 437059278, states[0] = 12.682525, states[40]= 0.000074
Saving checkpoint... 
Iteration: 445910292, states[0] = -84.803784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 452996080, states[0] = -84.298201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460555337, states[0] = -84.757661, states[40]= 0.000001
Saving checkpoint... 
Iteration: 468204718, states[0] = -82.936651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476882421, states[0] = -84.482331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 484759458, states[0] = 25.605458, states[40]= 0.000016
Saving checkpoint... 
Iteration: 492522541, states[0] = 25.336756, states[40]= 0.000014
Saving checkpoint... 
Iteration: 500130706, states[0] = -84.115267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508659149, states[0] = 4.987797, states[40]= 0.000215
Saving checkpoint... 
Iteration: 517143902, states[0] = -84.552056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 525667199, states[0] = -42.924120, states[40]= 0.000089
Saving checkpoint... 
Iteration: 534911305, states[0] = -83.868037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543514957, states[0] = -69.964635, states[40]= 0.000003
Saving checkpoint... 
Iteration: 552540869, states[0] = -84.708296, states[40]= 0.000001
Saving checkpoint... 
Iteration: 560586473, states[0] = -84.691894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 568980893, states[0] = 31.370466, states[40]= 0.003153
Saving checkpoint... 
Iteration: 578711572, states[0] = -84.735356, states[40]= 0.000001
Saving checkpoint... 
Iteration: 586285057, states[0] = 4.367973, states[40]= 0.000230
Saving checkpoint... 
Iteration: 594547886, states[0] = -84.800126, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603214469, states[0] = 23.230348, states[40]= 0.000011
Saving checkpoint... 
Iteration: 611447932, states[0] = -84.571952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 619223506, states[0] = -84.636535, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627913231, states[0] = 31.673019, states[40]= 0.019790
Saving checkpoint... 
Iteration: 635810856, states[0] = -79.632071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644773038, states[0] = -84.411616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652515109, states[0] = -84.235964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660712122, states[0] = 24.361723, states[40]= 0.000011
Saving checkpoint... 
Iteration: 668221770, states[0] = 4.908208, states[40]= 0.000217
Saving checkpoint... 
Iteration: 676113065, states[0] = -84.429402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684087019, states[0] = -51.189300, states[40]= 0.000035
Saving checkpoint... 
Iteration: 692381501, states[0] = -2.560184, states[40]= 0.000389
Saving checkpoint... 
Iteration: 701140688, states[0] = -84.528428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 709170726, states[0] = -84.392335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716753415, states[0] = 31.684672, states[40]= 0.007606
Saving checkpoint... 
Iteration: 724770367, states[0] = -84.758062, states[40]= 0.000001
Saving checkpoint... 
Iteration: 733409702, states[0] = -84.794907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 741329844, states[0] = -82.957669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749034329, states[0] = -19.596526, states[40]= 0.000256
Saving checkpoint... 
Iteration: 756512007, states[0] = -22.777363, states[40]= 0.000245
Saving checkpoint... 
Iteration: 764633226, states[0] = -84.150578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774023004, states[0] = 4.061359, states[40]= 0.000238
Saving checkpoint... 
Iteration: 782520301, states[0] = -84.617393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 791790942, states[0] = 31.683468, states[40]= 0.007533
Saving checkpoint... 
Iteration: 799442584, states[0] = -84.365239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807390799, states[0] = -12.342718, states[40]= 0.000351
Saving checkpoint... 
Iteration: 815458643, states[0] = -33.295526, states[40]= 0.000199
Saving checkpoint... 
Iteration: 824188442, states[0] = -84.511571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 833547617, states[0] = -6.009338, states[40]= 0.000416
Saving checkpoint... 
Iteration: 841067315, states[0] = -57.299886, states[40]= 0.000016
Saving checkpoint... 
Iteration: 849161830, states[0] = -84.195142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856935576, states[0] = -84.305054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864955738, states[0] = -83.164465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874185695, states[0] = -84.305631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883602632, states[0] = -40.590613, states[40]= 0.000113
Saving checkpoint... 
Iteration: 892513917, states[0] = -39.227999, states[40]= 0.000128
Saving checkpoint... 
Iteration: 900215210, states[0] = 16.382544, states[40]= 0.000039
Saving checkpoint... 
Iteration: 907967057, states[0] = 21.955016, states[40]= 0.000013
Saving checkpoint... 
Iteration: 915987702, states[0] = 31.623179, states[40]= 0.023894
Saving checkpoint... 
Iteration: 924008685, states[0] = -84.755165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932293944, states[0] = -84.541292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 939712951, states[0] = -83.945180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947159968, states[0] = -63.524889, states[40]= 0.000007
Saving checkpoint... 
Iteration: 955396038, states[0] = 26.029758, states[40]= 0.000020
Saving checkpoint... 
Iteration: 963737256, states[0] = 24.301097, states[40]= 0.000011
Saving checkpoint... 
Iteration: 972336392, states[0] = 31.419822, states[40]= 0.038123
Saving checkpoint... 
Iteration: 980152998, states[0] = 8.969593, states[40]= 0.000130
Saving checkpoint... 
Iteration: 987898372, states[0] = 18.711829, states[40]= 0.000025
Saving checkpoint... 
Iteration: 995986949, states[0] = -7.937724, states[40]= 0.000408
Saving checkpoint... 
Iteration: 1004807008, states[0] = -84.781387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013042480, states[0] = -84.249674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021162364, states[0] = -84.683158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1029517289, states[0] = -84.741159, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1038780873, states[0] = 21.294540, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1046704509, states[0] = -84.447431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054789005, states[0] = -84.638369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1063034508, states[0] = -78.387164, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071328519, states[0] = -27.436411, states[40]= 0.000241
Saving checkpoint... 
Iteration: 1079302211, states[0] = 28.714639, states[40]= 0.000141
Saving checkpoint... 
Iteration: 1087335354, states[0] = 31.187447, states[40]= 0.055195
Saving checkpoint... 
Iteration: 1095314498, states[0] = -84.580556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103360369, states[0] = -84.558590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111967083, states[0] = -84.446202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120778865, states[0] = -27.833020, states[40]= 0.000240
Saving checkpoint... 
Iteration: 1128817190, states[0] = -13.991636, states[40]= 0.000324
Saving checkpoint... 
Iteration: 1137124807, states[0] = 10.910474, states[40]= 0.000098
Saving checkpoint... 
Iteration: 1144966852, states[0] = -72.382396, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1152982399, states[0] = -31.871815, states[40]= 0.000213
Saving checkpoint... 
Iteration: 1160657296, states[0] = 31.089858, states[40]= 0.001916
Saving checkpoint... 
Iteration: 1169443229, states[0] = -84.252603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178411383, states[0] = -84.623499, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1187140536, states[0] = 16.207298, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1196116098, states[0] = -41.661081, states[40]= 0.000101
Saving checkpoint... 
Iteration: 1206004992, states[0] = -84.592661, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1213319656, states[0] = 6.327147, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1221388215, states[0] = -9.332928, states[40]= 0.000394
Saving checkpoint... 
Iteration: 1229863052, states[0] = -84.569517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1238241708, states[0] = -84.733968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246357754, states[0] = 20.337632, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1254828912, states[0] = -84.232748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264102924, states[0] = -84.688026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1271936409, states[0] = 24.705643, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1279731609, states[0] = 6.685166, states[40]= 0.000176
Saving checkpoint... 
Iteration: 1287578022, states[0] = -82.352358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296656028, states[0] = 27.144471, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1304587697, states[0] = -84.409945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312302890, states[0] = -82.300048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319622647, states[0] = -84.780657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1327559002, states[0] = -84.146292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336366474, states[0] = 8.366698, states[40]= 0.000141
Saving checkpoint... 
Iteration: 1344463774, states[0] = -39.049621, states[40]= 0.000130
Saving checkpoint... 
Iteration: 1352520915, states[0] = -47.071678, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1360511456, states[0] = 11.418934, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1368188311, states[0] = -84.720181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1378011970, states[0] = 29.726988, states[40]= 0.000368
Saving checkpoint... 
Iteration: 1387967532, states[0] = -84.441935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399196514, states[0] = -84.543347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1409508254, states[0] = -84.269514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420760531, states[0] = -84.551064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429645645, states[0] = -84.372435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437924185, states[0] = -65.658425, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1448084866, states[0] = -84.609475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455692367, states[0] = -1.130838, states[40]= 0.000364
Saving checkpoint... 
Iteration: 1465855989, states[0] = -84.247067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475467704, states[0] = 31.492720, states[40]= 0.004025
Saving checkpoint... 
Iteration: 1484790359, states[0] = -70.415759, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1492603589, states[0] = -84.334574, states[40]= 0.000000
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.657146
 - CaMKt in component CaMK (millimolar): 0.053861
 - cass in component intracellular_ions (millimolar): 0.000111
 - nai in component intracellular_ions (millimolar): 6.802708
 - nass in component intracellular_ions (millimolar): 6.802883
 - ki in component intracellular_ions (millimolar): 144.804315
 - kss in component intracellular_ions (millimolar): 144.804285
 - cansr in component intracellular_ions (millimolar): 2.200318
 - cajsr in component intracellular_ions (millimolar): 1.829699
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.010149
 - hf in component INa (dimensionless): 0.576667
 - hs in component INa (dimensionless): 0.576424
 - j in component INa (dimensionless): 0.575042
 - hsp in component INa (dimensionless): 0.328957
 - jp in component INa (dimensionless): 0.573478
 - mL in component INaL (dimensionless): 0.000347
 - hL in component INaL (dimensionless): 0.321066
 - hLp in component INaL (dimensionless): 0.136374
 - a in component Ito (dimensionless): 0.001244
 - iF in component Ito (dimensionless): 0.999216
 - iS in component Ito (dimensionless): 0.304242
 - ap in component Ito (dimensionless): 0.000634
 - iFp in component Ito (dimensionless): 0.999216
 - iSp in component Ito (dimensionless): 0.334550
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.811543
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990175
 - jca in component ICaL (dimensionless): 0.994202
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007637
 - xrf in component IKr (dimensionless): 0.002036
 - xrs in component IKr (dimensionless): 0.728721
 - xs1 in component IKs (dimensionless): 0.428109
 - xs2 in component IKs (dimensionless): 0.000287
 - xk1 in component IK1 (dimensionless): 0.996764
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
22:44:37 (33838): called boinc_finish(0)

</stderr_txt>
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