𝕏

Task 55260963

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pieske_333-conf_403_0
Workunit 26239626
Created 29 Jun 2024, 9:07:30 UTC
Sent 29 Jun 2024, 10:47:00 UTC
Report deadline 2 Jul 2024, 10:47:00 UTC
Received 30 Jun 2024, 5:31:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217204
Run time 8 hours 52 min
CPU time 8 hours 51 min 53 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 1.48 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.14 MB
Peak swap size 10.95 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pieske_333-conf_403.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pieske_333-conf_403_0_r989956841_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pieske_333-conf_403_0_r989956841_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.440348
     * GNaL_b in INaL: 0.005181
     * Gto_b in Ito: 0.088682
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030736
     * GKs_b in IKs: 0.002145
     * GK1_b in IK1: 0.162361
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 69.016258
     * GKb_b in IKb: 0.003700
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031376
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8483210, states[0] = -87.614816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17051945, states[0] = -5.440211, states[40]= 0.004447
Saving checkpoint... 
Iteration: 25545121, states[0] = 0.663351, states[40]= 0.006047
Saving checkpoint... 
Iteration: 34027263, states[0] = 13.064542, states[40]= 0.007946
Saving checkpoint... 
Iteration: 42506619, states[0] = 22.067158, states[40]= 0.039346
Saving checkpoint... 
Iteration: 50985349, states[0] = -87.635173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59468088, states[0] = -87.580902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68068003, states[0] = -34.669468, states[40]= 0.000322
Saving checkpoint... 
Iteration: 76556955, states[0] = -20.763621, states[40]= 0.001189
Saving checkpoint... 
Iteration: 85031777, states[0] = 6.465470, states[40]= 0.007051
Saving checkpoint... 
Iteration: 93506768, states[0] = 20.106394, states[40]= 0.016057
Saving checkpoint... 
Iteration: 101985286, states[0] = -87.661005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110516238, states[0] = 14.862605, states[40]= 0.008384
Saving checkpoint... 
Iteration: 119056868, states[0] = -26.667281, states[40]= 0.000720
Saving checkpoint... 
Iteration: 127535291, states[0] = -0.088815, states[40]= 0.006018
Saving checkpoint... 
Iteration: 136139527, states[0] = -87.634623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144637998, states[0] = -87.632575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153113304, states[0] = -87.529693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161590313, states[0] = -81.206557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170062725, states[0] = -41.528506, states[40]= 0.000134
Saving checkpoint... 
Iteration: 178539197, states[0] = -10.446532, states[40]= 0.003172
Saving checkpoint... 
Iteration: 187037961, states[0] = -9.931150, states[40]= 0.003318
Saving checkpoint... 
Iteration: 195617158, states[0] = -87.573832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204097018, states[0] = -87.180752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212572265, states[0] = -60.656530, states[40]= 0.000007
Saving checkpoint... 
Iteration: 221047788, states[0] = -28.244972, states[40]= 0.000626
Saving checkpoint... 
Iteration: 229530609, states[0] = -6.010216, states[40]= 0.004482
Saving checkpoint... 
Iteration: 238023408, states[0] = 0.680627, states[40]= 0.006174
Saving checkpoint... 
Iteration: 246492549, states[0] = 19.673977, states[40]= 0.014132
Saving checkpoint... 
Iteration: 254968949, states[0] = -87.659890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263520493, states[0] = 1.015590, states[40]= 0.006238
Saving checkpoint... 
Iteration: 272103111, states[0] = -87.541481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280576797, states[0] = -78.914996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289048578, states[0] = -38.512807, states[40]= 0.000201
Saving checkpoint... 
Iteration: 297524630, states[0] = -7.014365, states[40]= 0.004182
Saving checkpoint... 
Iteration: 306052346, states[0] = -45.877279, states[40]= 0.000072
Saving checkpoint... 
Iteration: 314529133, states[0] = -15.300442, states[40]= 0.001999
Saving checkpoint... 
Iteration: 323042337, states[0] = -34.695501, states[40]= 0.000322
Saving checkpoint... 
Iteration: 331516968, states[0] = -2.170250, states[40]= 0.005543
Saving checkpoint... 
Iteration: 340051261, states[0] = -49.032045, states[40]= 0.000045
Saving checkpoint... 
Iteration: 348557651, states[0] = -59.171020, states[40]= 0.000009
Saving checkpoint... 
Iteration: 357080410, states[0] = -87.025216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365587969, states[0] = -87.486228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374064923, states[0] = -74.815857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 382535851, states[0] = -33.971783, states[40]= 0.000350
Saving checkpoint... 
Iteration: 391012810, states[0] = -4.099819, states[40]= 0.005033
Saving checkpoint... 
Iteration: 399486243, states[0] = 15.452447, states[40]= 0.008585
Saving checkpoint... 
Iteration: 407979061, states[0] = 18.566091, states[40]= 0.011188
Saving checkpoint... 
Iteration: 416553288, states[0] = -62.783607, states[40]= 0.000005
Saving checkpoint... 
Iteration: 425029690, states[0] = -31.384266, states[40]= 0.000463
Saving checkpoint... 
Iteration: 433575112, states[0] = -87.268921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442061253, states[0] = -79.817800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450534880, states[0] = -41.805470, states[40]= 0.000129
Saving checkpoint... 
Iteration: 459005394, states[0] = -3.418363, states[40]= 0.005220
Saving checkpoint... 
Iteration: 467499777, states[0] = 1.300928, states[40]= 0.006291
Saving checkpoint... 
Iteration: 475973904, states[0] = 17.822105, states[40]= 0.010135
Saving checkpoint... 
Iteration: 484447212, states[0] = -87.663101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492911261, states[0] = -87.517887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501383284, states[0] = -71.031701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 509858428, states[0] = -36.628650, states[40]= 0.000255
Saving checkpoint... 
Iteration: 518329901, states[0] = -0.448603, states[40]= 0.005942
Saving checkpoint... 
Iteration: 526830178, states[0] = -1.562446, states[40]= 0.005690
Saving checkpoint... 
Iteration: 535306340, states[0] = 15.263763, states[40]= 0.008516
Saving checkpoint... 
Iteration: 543796691, states[0] = 19.458235, states[40]= 0.013358
Saving checkpoint... 
Iteration: 552263186, states[0] = -87.630110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560738644, states[0] = -87.525109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569216517, states[0] = -81.610517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577691118, states[0] = -44.891557, states[40]= 0.000083
Saving checkpoint... 
Iteration: 586165562, states[0] = -11.072253, states[40]= 0.002999
Saving checkpoint... 
Iteration: 594643445, states[0] = 9.302063, states[40]= 0.007399
Saving checkpoint... 
Iteration: 603117787, states[0] = 21.780937, states[40]= 0.034989
Saving checkpoint... 
Iteration: 611615636, states[0] = 22.302637, states[40]= 0.045828
Saving checkpoint... 
Iteration: 620133779, states[0] = 13.797741, states[40]= 0.008105
Saving checkpoint... 
Iteration: 628614125, states[0] = 22.221091, states[40]= 0.044021
Saving checkpoint... 
Iteration: 637112914, states[0] = 22.377781, states[40]= 0.047530
Saving checkpoint... 
Iteration: 645612672, states[0] = 22.118868, states[40]= 0.041800
Saving checkpoint... 
Iteration: 654080882, states[0] = -87.611013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662554473, states[0] = -87.391407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671061126, states[0] = -87.526466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679531073, states[0] = -69.265654, states[40]= 0.000002
Saving checkpoint... 
Iteration: 688007066, states[0] = -36.348175, states[40]= 0.000264
Saving checkpoint... 
Iteration: 696462249, states[0] = 12.130619, states[40]= 0.007789
Saving checkpoint... 
Iteration: 705035327, states[0] = -80.354152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713508982, states[0] = -42.347646, states[40]= 0.000120
Saving checkpoint... 
Iteration: 721984619, states[0] = -10.141500, states[40]= 0.003258
Saving checkpoint... 
Iteration: 730511134, states[0] = -47.553474, states[40]= 0.000057
Saving checkpoint... 
Iteration: 738965672, states[0] = 6.943452, states[40]= 0.007115
Saving checkpoint... 
Iteration: 747444275, states[0] = 18.927171, states[40]= 0.011909
Saving checkpoint... 
Iteration: 755917455, states[0] = -87.655033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764479548, states[0] = -9.061278, states[40]= 0.003570
Saving checkpoint... 
Iteration: 772956992, states[0] = 10.608345, states[40]= 0.007565
Saving checkpoint... 
Iteration: 781419952, states[0] = -87.669632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789886757, states[0] = -87.552639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798464582, states[0] = 3.124792, states[40]= 0.006599
Saving checkpoint... 
Iteration: 806987861, states[0] = -26.418421, states[40]= 0.000736
Saving checkpoint... 
Iteration: 815493911, states[0] = -35.798468, states[40]= 0.000282
Saving checkpoint... 
Iteration: 823988895, states[0] = -30.165961, states[40]= 0.000523
Saving checkpoint... 
Iteration: 832452025, states[0] = 9.958047, states[40]= 0.007481
Saving checkpoint... 
Iteration: 840962082, states[0] = 1.610568, states[40]= 0.006347
Saving checkpoint... 
Iteration: 849435329, states[0] = 18.381618, states[40]= 0.010878
Saving checkpoint... 
Iteration: 857898025, states[0] = -87.625292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866377667, states[0] = -87.544529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874848553, states[0] = -75.454017, states[40]= 0.000001
Saving checkpoint... 
Iteration: 883321891, states[0] = -37.723174, states[40]= 0.000222
Saving checkpoint... 
Iteration: 891788289, states[0] = 3.370261, states[40]= 0.006637
Saving checkpoint... 
Iteration: 900265219, states[0] = 17.627049, states[40]= 0.009927
Saving checkpoint... 
Iteration: 908756793, states[0] = 20.740807, states[40]= 0.020658
Saving checkpoint... 
Iteration: 917233157, states[0] = -87.650237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925788871, states[0] = -0.178726, states[40]= 0.006000
Saving checkpoint... 
Iteration: 934286957, states[0] = 0.818967, states[40]= 0.006201
Saving checkpoint... 
Iteration: 942807846, states[0] = -26.741516, states[40]= 0.000715
Saving checkpoint... 
Iteration: 951280543, states[0] = 4.829766, states[40]= 0.006845
Saving checkpoint... 
Iteration: 959796946, states[0] = -13.924814, states[40]= 0.002289
Saving checkpoint... 
Iteration: 968276276, states[0] = 6.793175, states[40]= 0.007097
Saving checkpoint... 
Iteration: 976754316, states[0] = 19.078667, states[40]= 0.012268
Saving checkpoint... 
Iteration: 985247703, states[0] = 21.250722, states[40]= 0.026398
Saving checkpoint... 
Iteration: 993771471, states[0] = 8.420515, states[40]= 0.007292
Saving checkpoint... 
Iteration: 1002318605, states[0] = -49.357847, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1010792322, states[0] = -14.586358, states[40]= 0.002145
Saving checkpoint... 
Iteration: 1019294093, states[0] = -18.254943, states[40]= 0.001500
Saving checkpoint... 
Iteration: 1027799784, states[0] = -27.343372, states[40]= 0.000679
Saving checkpoint... 
Iteration: 1036249430, states[0] = 18.624026, states[40]= 0.011290
Saving checkpoint... 
Iteration: 1044770611, states[0] = 5.285665, states[40]= 0.006907
Saving checkpoint... 
Iteration: 1053246060, states[0] = 19.328957, states[40]= 0.012953
Saving checkpoint... 
Iteration: 1061740269, states[0] = 21.174450, states[40]= 0.025395
Saving checkpoint... 
Iteration: 1070233833, states[0] = 23.816675, states[40]= 0.079902
Saving checkpoint... 
Iteration: 1078706337, states[0] = -87.614851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087242173, states[0] = 19.525152, states[40]= 0.013584
Saving checkpoint... 
Iteration: 1095725109, states[0] = 41.711817, states[40]= 0.052473
Saving checkpoint... 
Iteration: 1104221955, states[0] = -87.671972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112700654, states[0] = -87.606578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121173737, states[0] = -87.316105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129653095, states[0] = -69.878251, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1138123982, states[0] = -29.945630, states[40]= 0.000534
Saving checkpoint... 
Iteration: 1146608574, states[0] = -9.822375, states[40]= 0.003349
Saving checkpoint... 
Iteration: 1155137503, states[0] = -50.522874, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1163614041, states[0] = -19.725805, states[40]= 0.001307
Saving checkpoint... 
Iteration: 1172120693, states[0] = -30.095345, states[40]= 0.000526
Saving checkpoint... 
Iteration: 1180597177, states[0] = -0.620148, states[40]= 0.005905
Saving checkpoint... 
Iteration: 1189070716, states[0] = 17.120247, states[40]= 0.009483
Saving checkpoint... 
Iteration: 1197544172, states[0] = -87.666869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206016388, states[0] = -87.573772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214488421, states[0] = -84.692650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222962224, states[0] = -48.019068, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1231431867, states[0] = -7.807407, states[40]= 0.003943
Saving checkpoint... 
Iteration: 1239910318, states[0] = 10.589236, states[40]= 0.007564
Saving checkpoint... 
Iteration: 1248388347, states[0] = 21.146039, states[40]= 0.025039
Saving checkpoint... 
Iteration: 1256862361, states[0] = -87.638935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265335736, states[0] = -87.530969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273811237, states[0] = -79.572613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282299292, states[0] = -61.663768, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1290770342, states[0] = -23.009850, states[40]= 0.000980
Saving checkpoint... 
Iteration: 1299320431, states[0] = -87.139066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307891990, states[0] = 17.207402, states[40]= 0.009550
Saving checkpoint... 
Iteration: 1316364195, states[0] = -87.662605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324830534, states[0] = -87.536060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333293072, states[0] = -60.008259, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1341740661, states[0] = 5.478997, states[40]= 0.006931
Saving checkpoint... 
Iteration: 1350216844, states[0] = 19.128828, states[40]= 0.012394
Saving checkpoint... 
Iteration: 1358692905, states[0] = -87.661416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367165040, states[0] = -87.565092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375691573, states[0] = -87.662401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384165544, states[0] = -87.574752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392642379, states[0] = -86.831893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401084133, states[0] = -11.166219, states[40]= 0.002973
Saving checkpoint... 
Iteration: 1409636716, states[0] = -85.430365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418111700, states[0] = -51.200302, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1426601533, states[0] = -38.584445, states[40]= 0.000199
Saving checkpoint... 
Iteration: 1435076091, states[0] = -5.277665, states[40]= 0.004697
Saving checkpoint... 
Iteration: 1443550391, states[0] = 14.397755, states[40]= 0.008252
Saving checkpoint... 
Iteration: 1452071937, states[0] = -2.553669, states[40]= 0.005446
Saving checkpoint... 
Iteration: 1460545883, states[0] = 15.940527, states[40]= 0.008784
Saving checkpoint... 
Iteration: 1469043194, states[0] = 16.884847, states[40]= 0.009311
Saving checkpoint... 
Iteration: 1477518762, states[0] = -87.673504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486034644, states[0] = 19.909774, states[40]= 0.015134
Saving checkpoint... 
Iteration: 1494556895, states[0] = 6.853527, states[40]= 0.007104
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.549477
 - CaMKt in component CaMK (millimolar): 0.044281
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.077798
 - nass in component intracellular_ions (millimolar): 7.077946
 - ki in component intracellular_ions (millimolar): 144.838260
 - kss in component intracellular_ions (millimolar): 144.838229
 - cansr in component intracellular_ions (millimolar): 1.638784
 - cajsr in component intracellular_ions (millimolar): 1.197227
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007590
 - hf in component INa (dimensionless): 0.686624
 - hs in component INa (dimensionless): 0.686372
 - j in component INa (dimensionless): 0.674565
 - hsp in component INa (dimensionless): 0.440514
 - jp in component INa (dimensionless): 0.646298
 - mL in component INaL (dimensionless): 0.000200
 - hL in component INaL (dimensionless): 0.283614
 - hLp in component INaL (dimensionless): 0.130457
 - a in component Ito (dimensionless): 0.001024
 - iF in component Ito (dimensionless): 0.999527
 - iS in component Ito (dimensionless): 0.172271
 - ap in component Ito (dimensionless): 0.000522
 - iFp in component Ito (dimensionless): 0.999527
 - iSp in component Ito (dimensionless): 0.207672
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.801421
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966103
 - jca in component ICaL (dimensionless): 0.946631
 - ffp in component ICaL (dimensionless): 0.999840
 - fcafp in component ICaL (dimensionless): 0.999990
 - nca in component ICaL (dimensionless): 0.009641
 - xrf in component IKr (dimensionless): 0.031231
 - xrs in component IKr (dimensionless): 0.791566
 - xs1 in component IKs (dimensionless): 0.462631
 - xs2 in component IKs (dimensionless): 0.001352
 - xk1 in component IK1 (dimensionless): 0.996851
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:30:39 (18680): called boinc_finish(0)

</stderr_txt>
]]>