𝕏

Task 55251010

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_MID-conf_49_2
Workunit 26113005
Created 28 Jun 2024, 9:38:06 UTC
Sent 29 Jun 2024, 9:19:12 UTC
Report deadline 2 Jul 2024, 9:19:12 UTC
Received 30 Jun 2024, 9:00:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224057
Run time 1 hours 51 min
CPU time 1 hours 49 min 54 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 3.39 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.73 MB
Peak swap size 5.34 MB
Peak disk usage 0.32 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_MID-conf_49.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_MID-conf_49_2_r2004566760_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_MID-conf_49_2_r2004566760_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 112.961654
     * GNaL_b in INaL: 0.004480
     * Gto_b in Ito: 0.097929
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032980
     * GKs_b in IKs: 0.001771
     * GK1_b in IK1: 0.149082
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 70.330433
     * GKb_b in IKb: 0.003711
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037508
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6217831, states[0] = -84.531988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15119431, states[0] = 0.628865, states[40]= 0.000054
Saving checkpoint... 
Iteration: 23898964, states[0] = -86.798939, states[40]= 0.000002
Saving checkpoint... 
Iteration: 32826199, states[0] = -86.696740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 39968094, states[0] = -86.895062, states[40]= 0.000002
Saving checkpoint... 
Iteration: 48812275, states[0] = -86.696553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 57819105, states[0] = -86.733388, states[40]= 0.000002
Saving checkpoint... 
Iteration: 66810473, states[0] = -86.721441, states[40]= 0.000002
Saving checkpoint... 
Iteration: 75741561, states[0] = -86.396294, states[40]= 0.000001
Saving checkpoint... 
Iteration: 85392545, states[0] = -86.901958, states[40]= 0.000002
Saving checkpoint... 
Iteration: 94614623, states[0] = -3.571512, states[40]= 0.000170
Saving checkpoint... 
Iteration: 103915045, states[0] = -86.935635, states[40]= 0.000002
Saving checkpoint... 
Iteration: 112921798, states[0] = -86.944678, states[40]= 0.000002
Saving checkpoint... 
Iteration: 122124455, states[0] = -12.211314, states[40]= 0.000202
Saving checkpoint... 
Iteration: 131326251, states[0] = -86.802674, states[40]= 0.000002
Saving checkpoint... 
Iteration: 140250702, states[0] = -86.487970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 149243626, states[0] = -86.441069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158427461, states[0] = -86.955296, states[40]= 0.000002
Saving checkpoint... 
Iteration: 167275879, states[0] = -86.628661, states[40]= 0.000001
Saving checkpoint... 
Iteration: 176322522, states[0] = -86.795375, states[40]= 0.000002
Saving checkpoint... 
Iteration: 185419273, states[0] = -86.948500, states[40]= 0.000002
Saving checkpoint... 
Iteration: 194343861, states[0] = -86.844894, states[40]= 0.000002
Saving checkpoint... 
Iteration: 203179390, states[0] = -66.772445, states[40]= 0.000013
Saving checkpoint... 
Iteration: 212002546, states[0] = 17.593817, states[40]= 1.649964
Saving checkpoint... 
Iteration: 220927413, states[0] = -86.953815, states[40]= 0.000002
Saving checkpoint... 
Iteration: 229942629, states[0] = -86.964356, states[40]= 0.000002
Saving checkpoint... 
Iteration: 239061616, states[0] = 22.402200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 248189996, states[0] = -81.373814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257102819, states[0] = 3.248706, states[40]= 0.000085
Saving checkpoint... 
Iteration: 266353478, states[0] = -86.859857, states[40]= 0.000002
Saving checkpoint... 
Iteration: 275156578, states[0] = -41.500253, states[40]= 0.000283
Saving checkpoint... 
Iteration: 283997239, states[0] = -86.987925, states[40]= 0.000002
Saving checkpoint... 
Iteration: 292904876, states[0] = -86.929395, states[40]= 0.000002
Saving checkpoint... 
Iteration: 301984263, states[0] = -86.981919, states[40]= 0.000002
Saving checkpoint... 
Iteration: 310875423, states[0] = -86.892654, states[40]= 0.000002
Saving checkpoint... 
Iteration: 319751212, states[0] = -86.485068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 328698756, states[0] = -85.609416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337484630, states[0] = -86.979816, states[40]= 0.000002
Saving checkpoint... 
Iteration: 346535128, states[0] = 29.770565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355552569, states[0] = 25.517353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364548253, states[0] = 26.815758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373513453, states[0] = 28.255103, states[40]= -0.000000
Saving checkpoint... 
Iteration: 382498966, states[0] = -86.982281, states[40]= 0.000002
Saving checkpoint... 
Iteration: 391346985, states[0] = -86.839528, states[40]= 0.000002
Saving checkpoint... 
Iteration: 400221231, states[0] = -86.248360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409112125, states[0] = -2.623201, states[40]= 0.000166
Saving checkpoint... 
Iteration: 418029895, states[0] = 30.400593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426878654, states[0] = -86.889739, states[40]= 0.000002
Saving checkpoint... 
Iteration: 435951255, states[0] = -86.956957, states[40]= 0.000002
Saving checkpoint... 
Iteration: 444822396, states[0] = -86.779476, states[40]= 0.000002
Saving checkpoint... 
Iteration: 453583056, states[0] = 13.382644, states[40]= 0.000011
Saving checkpoint... 
Iteration: 462543274, states[0] = 28.134062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471638039, states[0] = -24.638052, states[40]= 0.000423
Saving checkpoint... 
Iteration: 480706697, states[0] = -86.064894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489622228, states[0] = -10.711945, states[40]= 0.000207
Saving checkpoint... 
Iteration: 498553042, states[0] = 25.370778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507274191, states[0] = -86.600875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 516217971, states[0] = -86.209831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524866019, states[0] = -86.864806, states[40]= 0.000002
Saving checkpoint... 
Iteration: 533784542, states[0] = -86.645874, states[40]= 0.000002
Saving checkpoint... 
Iteration: 542365318, states[0] = -86.862560, states[40]= 0.000002
Saving checkpoint... 
Iteration: 551252855, states[0] = -86.480269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 559982375, states[0] = -86.964728, states[40]= 0.000002
Saving checkpoint... 
Iteration: 569036663, states[0] = 29.523375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578103284, states[0] = 2.991916, states[40]= 0.000088
Saving checkpoint... 
Iteration: 587151249, states[0] = -36.303041, states[40]= 0.000426
Saving checkpoint... 
Iteration: 596056594, states[0] = 24.198374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605012805, states[0] = 27.935665, states[40]= -0.000000
Saving checkpoint... 
Iteration: 614088436, states[0] = 10.823566, states[40]= 0.000021
Saving checkpoint... 
Iteration: 623099118, states[0] = 5.332418, states[40]= 0.000061
Saving checkpoint... 
Iteration: 632227180, states[0] = -86.285638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641341667, states[0] = -86.812593, states[40]= 0.000002
Saving checkpoint... 
Iteration: 650219691, states[0] = -86.217353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659127119, states[0] = -15.100326, states[40]= 0.000204
Saving checkpoint... 
Iteration: 668142940, states[0] = -28.789680, states[40]= 0.000530
Saving checkpoint... 
Iteration: 676800997, states[0] = -86.699557, states[40]= 0.000002
Saving checkpoint... 
Iteration: 685640499, states[0] = -26.695743, states[40]= 0.000490
Saving checkpoint... 
Iteration: 694553321, states[0] = 25.286799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703510614, states[0] = 26.597356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712332576, states[0] = -86.787765, states[40]= 0.000002
Saving checkpoint... 
Iteration: 721309244, states[0] = -86.723781, states[40]= 0.000002
Saving checkpoint... 
Iteration: 730254966, states[0] = -86.481650, states[40]= 0.000001
Saving checkpoint... 
Iteration: 739332949, states[0] = -86.786906, states[40]= 0.000002
Saving checkpoint... 
Iteration: 748309913, states[0] = -86.724107, states[40]= 0.000002
Saving checkpoint... 
Iteration: 757312889, states[0] = -86.732562, states[40]= 0.000002
Saving checkpoint... 
Iteration: 766213987, states[0] = -86.152197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775211066, states[0] = -86.116894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784185712, states[0] = -75.767341, states[40]= 0.000003
Saving checkpoint... 
Iteration: 793205399, states[0] = -86.010776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802229894, states[0] = -86.297186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811284237, states[0] = -86.626544, states[40]= 0.000002
Saving checkpoint... 
Iteration: 820172727, states[0] = -58.529870, states[40]= 0.000039
Saving checkpoint... 
Iteration: 829279830, states[0] = -86.606112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 838319258, states[0] = -86.745614, states[40]= 0.000002
Saving checkpoint... 
Iteration: 847130246, states[0] = -17.891769, states[40]= 0.000224
Saving checkpoint... 
Iteration: 856132988, states[0] = -20.299592, states[40]= 0.000270
Saving checkpoint... 
Iteration: 865103477, states[0] = 2.894236, states[40]= 0.000089
Saving checkpoint... 
Iteration: 873991638, states[0] = -86.948453, states[40]= 0.000002
Saving checkpoint... 
Iteration: 882734401, states[0] = -86.328279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 891772500, states[0] = -86.567586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 900684806, states[0] = -74.411350, states[40]= 0.000004
Saving checkpoint... 
Iteration: 909747079, states[0] = -86.419045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 918946830, states[0] = -86.923487, states[40]= 0.000002
Saving checkpoint... 
Iteration: 927911515, states[0] = -86.895401, states[40]= 0.000002
Saving checkpoint... 
Iteration: 936549925, states[0] = 26.344508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945645798, states[0] = -31.267804, states[40]= 0.000528
Saving checkpoint... 
Iteration: 954600196, states[0] = 4.755638, states[40]= 0.000067
Saving checkpoint... 
Iteration: 963712066, states[0] = -86.116727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972663029, states[0] = -48.004701, states[40]= 0.000143
Saving checkpoint... 
Iteration: 981431345, states[0] = -86.908819, states[40]= 0.000002
Saving checkpoint... 
Iteration: 989771299, states[0] = -86.555237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 998771846, states[0] = -86.557393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1007623101, states[0] = -11.437389, states[40]= 0.000204
Saving checkpoint... 
Iteration: 1016510245, states[0] = 26.336792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025414473, states[0] = -86.891942, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1034351264, states[0] = -86.806557, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1043368745, states[0] = -86.835881, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1052298562, states[0] = -86.666727, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1061383134, states[0] = -86.855177, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1070488995, states[0] = -86.934940, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1079586404, states[0] = 11.821243, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1088868279, states[0] = -86.832232, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1097903287, states[0] = -86.876379, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1104399575, states[0] = -86.872027, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1113539032, states[0] = 29.094045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122853412, states[0] = -86.804912, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1129099497, states[0] = 5.147714, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1137948209, states[0] = -86.910447, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1146650838, states[0] = -35.850554, states[40]= 0.000435
Saving checkpoint... 
Iteration: 1155780006, states[0] = -86.585696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1164580307, states[0] = 14.673570, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1173412859, states[0] = -86.881013, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1182597342, states[0] = 6.313536, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1191695672, states[0] = -84.841736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200519527, states[0] = 30.142977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209455892, states[0] = -86.910448, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1218424027, states[0] = -86.887923, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1227252745, states[0] = -86.435190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1236303099, states[0] = -86.670543, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1245393724, states[0] = -86.856463, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1254355083, states[0] = -86.799537, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1263225979, states[0] = -86.233402, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1272204271, states[0] = -85.940323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281209929, states[0] = -86.066880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290174610, states[0] = -60.629613, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1299231953, states[0] = -86.281144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1308212931, states[0] = -86.103831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316926080, states[0] = -86.883332, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1325807235, states[0] = -86.678369, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1334860010, states[0] = -86.803021, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1343759871, states[0] = -86.470606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1352755778, states[0] = -86.445750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1361738204, states[0] = -86.325868, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1370624251, states[0] = -12.432708, states[40]= 0.000202
Saving checkpoint... 
Iteration: 1379548089, states[0] = 26.889870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388567942, states[0] = 19.986993, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1397513452, states[0] = 28.278685, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1406564101, states[0] = 21.494604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1415439796, states[0] = -86.887276, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1424470590, states[0] = -86.904517, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1433313967, states[0] = -86.692166, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1442392070, states[0] = -86.841981, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1451205572, states[0] = -85.968632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457720720, states[0] = -86.173170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466364265, states[0] = -86.801715, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1475139050, states[0] = -25.388571, states[40]= 0.000444
Saving checkpoint... 
Iteration: 1483813819, states[0] = -86.688464, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1492359934, states[0] = -86.792807, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.787518
 - CaMKt in component CaMK (millimolar): 0.026228
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 8.144179
 - nass in component intracellular_ions (millimolar): 8.144342
 - ki in component intracellular_ions (millimolar): 143.166618
 - kss in component intracellular_ions (millimolar): 143.166576
 - cansr in component intracellular_ions (millimolar): 2.134675
 - cajsr in component intracellular_ions (millimolar): 2.075560
 - cai in component intracellular_ions (millimolar): 0.000098
 - m in component INa (dimensionless): 0.008195
 - hf in component INa (dimensionless): 0.659071
 - hs in component INa (dimensionless): 0.659038
 - j in component INa (dimensionless): 0.658850
 - hsp in component INa (dimensionless): 0.410949
 - jp in component INa (dimensionless): 0.658714
 - mL in component INaL (dimensionless): 0.000232
 - hL in component INaL (dimensionless): 0.455863
 - hLp in component INaL (dimensionless): 0.222754
 - a in component Ito (dimensionless): 0.001077
 - iF in component Ito (dimensionless): 0.999460
 - iS in component Ito (dimensionless): 0.538474
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999460
 - iSp in component Ito (dimensionless): 0.582437
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.881466
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999658
 - jca in component ICaL (dimensionless): 0.999945
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004190
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.502732
 - xs1 in component IKs (dimensionless): 0.327800
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997034
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
10:50:17 (19660): called boinc_finish(0)

</stderr_txt>
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