𝕏

Task 54976590

Name HuVeMOp_20240627192118166668_ORdGradInc_k_25-Schmidt_333-conf_779_1
Workunit 26104223
Created 27 Jun 2024, 17:40:55 UTC
Sent 27 Jun 2024, 20:03:37 UTC
Report deadline 30 Jun 2024, 20:03:37 UTC
Received 28 Jun 2024, 2:04:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216914
Run time 3 hours 5 min 8 sec
CPU time 3 hours 2 min 13 sec
Validate state Valid
Credit 41.95
Device peak FLOPS 1.97 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 3.71 MB
Peak swap size 1.47 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Schmidt_333-conf_779.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Schmidt_333-conf_779_1_r552730138_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Schmidt_333-conf_779_1_r552730138_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 90.523273
     * GNaL_b in INaL: 0.007357
     * Gto_b in Ito: 0.073406
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031038
     * GKs_b in IKs: 0.002073
     * GK1_b in IK1: 0.160097
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 74.553017
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034714
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8389742, states[0] = 7.782557, states[40]= 0.002694
Saving checkpoint... 
Iteration: 16512078, states[0] = 30.550870, states[40]= 0.015421
Saving checkpoint... 
Iteration: 24613316, states[0] = -62.744298, states[40]= 0.000028
Saving checkpoint... 
Iteration: 32715823, states[0] = 11.972568, states[40]= 0.000048
Saving checkpoint... 
Iteration: 40929295, states[0] = -43.115787, states[40]= 0.000191
Saving checkpoint... 
Iteration: 49152940, states[0] = -84.893155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 55853180, states[0] = 27.446413, states[40]= 0.000232
Saving checkpoint... 
Iteration: 64233291, states[0] = -7.669630, states[40]= 0.000341
Saving checkpoint... 
Iteration: 72343189, states[0] = 30.058532, states[40]= 0.004730
Saving checkpoint... 
Iteration: 80764219, states[0] = -51.649353, states[40]= 0.000077
Saving checkpoint... 
Iteration: 89522908, states[0] = 24.172465, states[40]= 0.000024
Saving checkpoint... 
Iteration: 97693283, states[0] = 21.657529, states[40]= 0.000006
Saving checkpoint... 
Iteration: 105883429, states[0] = 5.012095, states[40]= 0.000108
Saving checkpoint... 
Iteration: 114095777, states[0] = -54.001394, states[40]= 0.000059
Saving checkpoint... 
Iteration: 122117416, states[0] = -82.617728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 130278451, states[0] = -78.772153, states[40]= 0.000003
Saving checkpoint... 
Iteration: 138490348, states[0] = 30.200357, states[40]= 0.540153
Saving checkpoint... 
Iteration: 146693498, states[0] = 18.589635, states[40]= 0.000005
Saving checkpoint... 
Iteration: 154891820, states[0] = -9.498276, states[40]= 0.000302
Saving checkpoint... 
Iteration: 163245288, states[0] = -38.269857, states[40]= 0.000214
Saving checkpoint... 
Iteration: 171415380, states[0] = -43.752562, states[40]= 0.000149
Saving checkpoint... 
Iteration: 179749946, states[0] = -46.414265, states[40]= 0.000120
Saving checkpoint... 
Iteration: 187977516, states[0] = -84.982464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 196382897, states[0] = -3.439205, states[40]= 0.000265
Saving checkpoint... 
Iteration: 204247165, states[0] = -45.991057, states[40]= 0.000124
Saving checkpoint... 
Iteration: 212294547, states[0] = -84.810537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220535307, states[0] = 7.670895, states[40]= 0.000066
Saving checkpoint... 
Iteration: 228930669, states[0] = -72.678695, states[40]= 0.000007
Saving checkpoint... 
Iteration: 237248784, states[0] = -52.360160, states[40]= 0.000069
Saving checkpoint... 
Iteration: 245185288, states[0] = 17.568480, states[40]= 0.000006
Saving checkpoint... 
Iteration: 253381802, states[0] = -9.279210, states[40]= 0.000301
Saving checkpoint... 
Iteration: 261603968, states[0] = -82.878958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 269680081, states[0] = 19.263048, states[40]= 0.000004
Saving checkpoint... 
Iteration: 277799563, states[0] = -84.952438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 286032462, states[0] = 4.626742, states[40]= 0.000111
Saving checkpoint... 
Iteration: 294414654, states[0] = -58.905565, states[40]= 0.000035
Saving checkpoint... 
Iteration: 302626604, states[0] = -84.907988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311024269, states[0] = 9.204931, states[40]= 0.000048
Saving checkpoint... 
Iteration: 319247326, states[0] = -61.428766, states[40]= 0.000026
Saving checkpoint... 
Iteration: 327481487, states[0] = 30.242741, states[40]= 0.013508
Saving checkpoint... 
Iteration: 335711205, states[0] = -15.345531, states[40]= 0.000261
Saving checkpoint... 
Iteration: 343936932, states[0] = -84.460944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 352136537, states[0] = 29.317270, states[40]= 0.395138
Saving checkpoint... 
Iteration: 360155771, states[0] = 27.412842, states[40]= 0.000254
Saving checkpoint... 
Iteration: 368006538, states[0] = 17.445763, states[40]= 0.000006
Saving checkpoint... 
Iteration: 376146492, states[0] = 29.924372, states[40]= 0.004132
Saving checkpoint... 
Iteration: 384302510, states[0] = 29.102540, states[40]= 0.159198
Saving checkpoint... 
Iteration: 392489036, states[0] = 25.949063, states[40]= 0.000082
Saving checkpoint... 
Iteration: 400590987, states[0] = -83.232179, states[40]= 0.000001
Saving checkpoint... 
Iteration: 408778860, states[0] = -84.854264, states[40]= 0.000001
Saving checkpoint... 
Iteration: 416958524, states[0] = -57.399199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 425143209, states[0] = 29.567673, states[40]= 0.002284
Saving checkpoint... 
Iteration: 433331119, states[0] = 18.819815, states[40]= 0.000005
Saving checkpoint... 
Iteration: 441316269, states[0] = 26.533383, states[40]= 0.000126
Saving checkpoint... 
Iteration: 449487719, states[0] = 23.689306, states[40]= 0.000018
Saving checkpoint... 
Iteration: 457651518, states[0] = 24.775509, states[40]= 0.000036
Saving checkpoint... 
Iteration: 465804392, states[0] = 29.888298, states[40]= 0.003839
Saving checkpoint... 
Iteration: 474162683, states[0] = 17.388917, states[40]= 0.000006
Saving checkpoint... 
Iteration: 482383210, states[0] = -42.358880, states[40]= 0.000164
Saving checkpoint... 
Iteration: 490601661, states[0] = -84.817247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 498810069, states[0] = 26.744321, states[40]= 0.000149
Saving checkpoint... 
Iteration: 506296907, states[0] = 30.246554, states[40]= 0.013656
Saving checkpoint... 
Iteration: 514209003, states[0] = -36.715104, states[40]= 0.000230
Saving checkpoint... 
Iteration: 522593318, states[0] = -84.729717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 530753211, states[0] = -84.544043, states[40]= 0.000001
Saving checkpoint... 
Iteration: 538968733, states[0] = 28.427260, states[40]= 0.000623
Saving checkpoint... 
Iteration: 547110699, states[0] = -84.985815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 555325743, states[0] = 14.469842, states[40]= 0.000014
Saving checkpoint... 
Iteration: 563507456, states[0] = 2.175117, states[40]= 0.000157
Saving checkpoint... 
Iteration: 571688960, states[0] = -17.272522, states[40]= 0.000250
Saving checkpoint... 
Iteration: 579871670, states[0] = -40.040204, states[40]= 0.000191
Saving checkpoint... 
Iteration: 588037289, states[0] = -39.742507, states[40]= 0.000195
Saving checkpoint... 
Iteration: 596215835, states[0] = -56.224115, states[40]= 0.000047
Saving checkpoint... 
Iteration: 604235142, states[0] = -82.220395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 612459291, states[0] = 29.148630, states[40]= 0.001331
Saving checkpoint... 
Iteration: 620693988, states[0] = -30.955430, states[40]= 0.000268
Saving checkpoint... 
Iteration: 628919977, states[0] = -84.791328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637158356, states[0] = 9.186450, states[40]= 0.000048
Saving checkpoint... 
Iteration: 645576052, states[0] = -84.580922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 653833774, states[0] = 0.220909, states[40]= 0.000197
Saving checkpoint... 
Iteration: 662058485, states[0] = -78.629783, states[40]= 0.000003
Saving checkpoint... 
Iteration: 669737573, states[0] = -84.430212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 677967232, states[0] = 22.392672, states[40]= 0.000008
Saving checkpoint... 
Iteration: 685863770, states[0] = -43.517197, states[40]= 0.000150
Saving checkpoint... 
Iteration: 693870756, states[0] = -53.591785, states[40]= 0.000061
Saving checkpoint... 
Iteration: 702076908, states[0] = -84.747524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 710274379, states[0] = 30.117049, states[40]= 0.030180
Saving checkpoint... 
Iteration: 718666353, states[0] = -6.278367, states[40]= 0.000295
Saving checkpoint... 
Iteration: 726767469, states[0] = 28.973457, states[40]= 0.212318
Saving checkpoint... 
Iteration: 734690182, states[0] = -40.884258, states[40]= 0.000181
Saving checkpoint... 
Iteration: 742870188, states[0] = -59.380436, states[40]= 0.000033
Saving checkpoint... 
Iteration: 750913602, states[0] = -84.862180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 759118862, states[0] = 26.042089, states[40]= 0.000087
Saving checkpoint... 
Iteration: 767006321, states[0] = -22.279876, states[40]= 0.000244
Saving checkpoint... 
Iteration: 775201094, states[0] = -60.486860, states[40]= 0.000029
Saving checkpoint... 
Iteration: 783610381, states[0] = 28.635591, states[40]= 0.000761
Saving checkpoint... 
Iteration: 791829832, states[0] = -11.858421, states[40]= 0.000288
Saving checkpoint... 
Iteration: 800208919, states[0] = -75.536710, states[40]= 0.000004
Saving checkpoint... 
Iteration: 808423430, states[0] = 30.071817, states[40]= 0.524353
Saving checkpoint... 
Iteration: 816640474, states[0] = 9.140214, states[40]= 0.000049
Saving checkpoint... 
Iteration: 824865572, states[0] = -64.411119, states[40]= 0.000019
Saving checkpoint... 
Iteration: 833066874, states[0] = -84.788305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841273862, states[0] = 27.620604, states[40]= 0.000300
Saving checkpoint... 
Iteration: 849176471, states[0] = -37.948522, states[40]= 0.000216
Saving checkpoint... 
Iteration: 857172243, states[0] = -33.464181, states[40]= 0.000257
Saving checkpoint... 
Iteration: 865345564, states[0] = -43.170076, states[40]= 0.000154
Saving checkpoint... 
Iteration: 873403629, states[0] = -84.881847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 881798130, states[0] = 10.984714, states[40]= 0.000033
Saving checkpoint... 
Iteration: 889905262, states[0] = -84.917807, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898081477, states[0] = 29.676576, states[40]= 0.464251
Saving checkpoint... 
Iteration: 906299607, states[0] = 8.043389, states[40]= 0.000061
Saving checkpoint... 
Iteration: 914539289, states[0] = -83.066467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 922756882, states[0] = 30.165752, states[40]= 0.007473
Saving checkpoint... 
Iteration: 930745207, states[0] = 29.396797, states[40]= 0.413301
Saving checkpoint... 
Iteration: 938796306, states[0] = 8.084062, states[40]= 0.000061
Saving checkpoint... 
Iteration: 946994118, states[0] = -30.171116, states[40]= 0.000269
Saving checkpoint... 
Iteration: 955169716, states[0] = -42.907805, states[40]= 0.000157
Saving checkpoint... 
Iteration: 963560765, states[0] = -84.870295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 971773599, states[0] = 21.017905, states[40]= 0.000005
Saving checkpoint... 
Iteration: 979988919, states[0] = -27.614029, states[40]= 0.000266
Saving checkpoint... 
Iteration: 987708465, states[0] = -84.556811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 995750897, states[0] = 29.988274, states[40]= 0.004601
Saving checkpoint... 
Iteration: 1003849480, states[0] = -67.033603, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1012233588, states[0] = 33.448031, states[40]= 1.176761
Saving checkpoint... 
Iteration: 1020444799, states[0] = 15.207724, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1028645850, states[0] = -20.902318, states[40]= 0.000241
Saving checkpoint... 
Iteration: 1036861669, states[0] = -83.487731, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1045135781, states[0] = -8.994733, states[40]= 0.000301
Saving checkpoint... 
Iteration: 1053351367, states[0] = -76.952906, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1061538567, states[0] = -84.678202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1069743749, states[0] = 29.943520, states[40]= 0.004195
Saving checkpoint... 
Iteration: 1077951679, states[0] = 5.990036, states[40]= 0.000088
Saving checkpoint... 
Iteration: 1086166269, states[0] = -55.420453, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1094582240, states[0] = 27.465677, states[40]= 0.000261
Saving checkpoint... 
Iteration: 1102794339, states[0] = -5.925078, states[40]= 0.000292
Saving checkpoint... 
Iteration: 1111012203, states[0] = -76.871902, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1119000332, states[0] = -60.860890, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1127373425, states[0] = -84.807206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1135516886, states[0] = -82.919824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1143731409, states[0] = 30.167908, states[40]= 0.026173
Saving checkpoint... 
Iteration: 1152015748, states[0] = -83.121538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1160245737, states[0] = 25.892679, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1168455662, states[0] = -7.495113, states[40]= 0.000301
Saving checkpoint... 
Iteration: 1176476735, states[0] = -37.493013, states[40]= 0.000221
Saving checkpoint... 
Iteration: 1184467045, states[0] = -25.662735, states[40]= 0.000257
Saving checkpoint... 
Iteration: 1192849825, states[0] = -84.196693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1201214482, states[0] = 32.757707, states[40]= 1.036245
Saving checkpoint... 
Iteration: 1209429125, states[0] = 13.042012, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1217298959, states[0] = -28.196756, states[40]= 0.000268
Saving checkpoint... 
Iteration: 1225274777, states[0] = 2.040816, states[40]= 0.000160
Saving checkpoint... 
Iteration: 1233495940, states[0] = -71.134972, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1241541428, states[0] = -84.945317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1249746172, states[0] = 20.805215, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1257776559, states[0] = -3.170664, states[40]= 0.000259
Saving checkpoint... 
Iteration: 1265998283, states[0] = -78.752668, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1274393232, states[0] = 29.119504, states[40]= 0.001262
Saving checkpoint... 
Iteration: 1282771238, states[0] = -0.120396, states[40]= 0.000204
Saving checkpoint... 
Iteration: 1290971256, states[0] = -45.189185, states[40]= 0.000132
Saving checkpoint... 
Iteration: 1299173427, states[0] = -84.285164, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1307386025, states[0] = 30.053879, states[40]= 0.005274
Saving checkpoint... 
Iteration: 1315602582, states[0] = -1.476164, states[40]= 0.000232
Saving checkpoint... 
Iteration: 1323799061, states[0] = -42.290454, states[40]= 0.000164
Saving checkpoint... 
Iteration: 1332192713, states[0] = -84.872429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340254862, states[0] = 9.089051, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1348269838, states[0] = -5.968430, states[40]= 0.000291
Saving checkpoint... 
Iteration: 1356489607, states[0] = -79.146002, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1364707368, states[0] = 29.846188, states[40]= 0.054033
Saving checkpoint... 
Iteration: 1372999180, states[0] = -84.260642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381184130, states[0] = -84.826269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1389371510, states[0] = 29.833759, states[40]= 0.055220
Saving checkpoint... 
Iteration: 1397603659, states[0] = -13.344736, states[40]= 0.000277
Saving checkpoint... 
Iteration: 1405833344, states[0] = -84.530388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414257369, states[0] = 0.608244, states[40]= 0.000190
Saving checkpoint... 
Iteration: 1422470311, states[0] = -61.267603, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1430687426, states[0] = -84.915696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1438868028, states[0] = 30.106347, states[40]= 0.031897
Saving checkpoint... 
Iteration: 1447178428, states[0] = -84.833039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455360834, states[0] = 28.951020, states[40]= 0.248193
Saving checkpoint... 
Iteration: 1463559906, states[0] = 19.757773, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1471786991, states[0] = -45.791973, states[40]= 0.000125
Saving checkpoint... 
Iteration: 1479910849, states[0] = 6.517023, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1488098350, states[0] = -18.679599, states[40]= 0.000243
Saving checkpoint... 
Iteration: 1496081183, states[0] = 1.904634, states[40]= 0.000163
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.815598
 - CaMKt in component CaMK (millimolar): 0.213527
 - cass in component intracellular_ions (millimolar): 0.000171
 - nai in component intracellular_ions (millimolar): 7.102218
 - nass in component intracellular_ions (millimolar): 7.102563
 - ki in component intracellular_ions (millimolar): 144.030526
 - kss in component intracellular_ions (millimolar): 144.030493
 - cansr in component intracellular_ions (millimolar): 3.283110
 - cajsr in component intracellular_ions (millimolar): 1.868181
 - cai in component intracellular_ions (millimolar): 0.000160
 - m in component INa (dimensionless): 0.009989
 - hf in component INa (dimensionless): 0.583000
 - hs in component INa (dimensionless): 0.581928
 - j in component INa (dimensionless): 0.547828
 - hsp in component INa (dimensionless): 0.329863
 - jp in component INa (dimensionless): 0.502905
 - mL in component INaL (dimensionless): 0.000337
 - hL in component INaL (dimensionless): 0.175160
 - hLp in component INaL (dimensionless): 0.070824
 - a in component Ito (dimensionless): 0.001231
 - iF in component Ito (dimensionless): 0.999233
 - iS in component Ito (dimensionless): 0.127109
 - ap in component Ito (dimensionless): 0.000627
 - iFp in component Ito (dimensionless): 0.999233
 - iSp in component Ito (dimensionless): 0.141278
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.668670
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.924261
 - jca in component ICaL (dimensionless): 0.907613
 - ffp in component ICaL (dimensionless): 0.998667
 - fcafp in component ICaL (dimensionless): 0.999929
 - nca in component ICaL (dimensionless): 0.041033
 - xrf in component IKr (dimensionless): 0.110608
 - xrs in component IKr (dimensionless): 0.878325
 - xs1 in component IKs (dimensionless): 0.577001
 - xs2 in component IKs (dimensionless): 0.008430
 - xk1 in component IK1 (dimensionless): 0.996746
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
21:14:00 (1604): called boinc_finish(0)

</stderr_txt>
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