𝕏

Task 54925815

Name HuVeMOp_20240627044042218173_ORdGradInc_k_24-Pueyo_APDR-conf_679_1
Workunit 26081142
Created 27 Jun 2024, 2:40:51 UTC
Sent 27 Jun 2024, 4:28:56 UTC
Report deadline 30 Jun 2024, 14:04:56 UTC
Received 27 Jun 2024, 8:50:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217041
Run time 3 hours 3 min 37 sec
CPU time 3 hours 2 min 40 sec
Validate state Valid
Credit 56.83
Device peak FLOPS 3.79 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.90 MB
Peak swap size 4.10 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627044042218173_ORdGradInc_k_24-Pueyo_APDR-conf_679.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627044042218173_ORdGradInc_k_24-Pueyo_APDR-conf_679_1_r250136485_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627044042218173_ORdGradInc_k_24-Pueyo_APDR-conf_679_1_r250136485_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 113.446684
     * GNaL_b in INaL: 0.007453
     * Gto_b in Ito: 0.073491
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033234
     * GKs_b in IKs: 0.001756
     * GK1_b in IK1: 0.147839
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 66.939806
     * GKb_b in IKb: 0.003964
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033221
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11921678, states[0] = -94.951897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23904704, states[0] = -94.922076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35874097, states[0] = -94.896800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47800076, states[0] = -94.844402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59760339, states[0] = -94.797907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71398419, states[0] = -94.885239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83367684, states[0] = -94.870868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95317758, states[0] = -94.841552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107237907, states[0] = -94.755711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119223153, states[0] = -94.730283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131182826, states[0] = -94.636939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143184703, states[0] = -94.645237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155128093, states[0] = -47.622117, states[40]= 0.000041
Saving checkpoint... 
Iteration: 167045058, states[0] = 13.737605, states[40]= 0.005359
Saving checkpoint... 
Iteration: 178997496, states[0] = -94.895442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191009876, states[0] = 24.967164, states[40]= 0.055096
Saving checkpoint... 
Iteration: 202971095, states[0] = -94.891520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214998432, states[0] = -94.895242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226979049, states[0] = -94.892604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238916048, states[0] = -94.879897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250880981, states[0] = -94.868754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262818384, states[0] = -94.836722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274740140, states[0] = -94.755315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286711309, states[0] = -94.705669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298623324, states[0] = -42.503650, states[40]= 0.000090
Saving checkpoint... 
Iteration: 310581696, states[0] = -4.090632, states[40]= 0.003645
Saving checkpoint... 
Iteration: 322468521, states[0] = -94.890823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334304147, states[0] = -94.826195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346024403, states[0] = 20.999680, states[40]= 0.008020
Saving checkpoint... 
Iteration: 357984023, states[0] = -94.893133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369964060, states[0] = -94.890053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381938475, states[0] = -94.885140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393866230, states[0] = -94.862719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405870804, states[0] = -94.864631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416785596, states[0] = -94.810081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428341509, states[0] = -94.850726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440234170, states[0] = -94.745952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452210082, states[0] = -94.703173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464169280, states[0] = -94.044206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476120835, states[0] = -39.959580, states[40]= 0.000131
Saving checkpoint... 
Iteration: 487992053, states[0] = -94.894136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499931227, states[0] = -94.883453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511840988, states[0] = -94.850395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523786183, states[0] = -94.810577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535736048, states[0] = -94.748865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547658277, states[0] = -86.441791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559563453, states[0] = 5.999109, states[40]= 0.004920
Saving checkpoint... 
Iteration: 571526384, states[0] = 20.417041, states[40]= 0.007383
Saving checkpoint... 
Iteration: 583456553, states[0] = -94.888617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595392116, states[0] = -94.872445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606858816, states[0] = -94.859305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618390312, states[0] = -94.871823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630209997, states[0] = -94.702908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642125601, states[0] = -44.889539, states[40]= 0.000063
Saving checkpoint... 
Iteration: 653981663, states[0] = -94.892636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665854017, states[0] = -94.857010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677726028, states[0] = -94.732345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689589683, states[0] = -10.397307, states[40]= 0.002292
Saving checkpoint... 
Iteration: 701406848, states[0] = -94.876996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713299686, states[0] = -94.822389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725135401, states[0] = -55.671505, states[40]= 0.000011
Saving checkpoint... 
Iteration: 736938744, states[0] = -94.885002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748765320, states[0] = -94.788510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760427936, states[0] = -94.882536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772305000, states[0] = -94.826619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784171674, states[0] = -94.329234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796035250, states[0] = 17.465950, states[40]= 0.005949
Saving checkpoint... 
Iteration: 807890216, states[0] = -94.871686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819696540, states[0] = -94.675297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831573209, states[0] = 1.139850, states[40]= 0.004493
Saving checkpoint... 
Iteration: 843464664, states[0] = -94.889894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855320700, states[0] = -94.837922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867187883, states[0] = -94.654411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879017657, states[0] = 22.752593, states[40]= 0.013617
Saving checkpoint... 
Iteration: 890878455, states[0] = -94.867394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902750520, states[0] = -94.769778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914659201, states[0] = -87.701697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926538444, states[0] = 16.294256, states[40]= 0.005692
Saving checkpoint... 
Iteration: 938390804, states[0] = -94.871815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950239544, states[0] = -94.754016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962050639, states[0] = 11.507476, states[40]= 0.005200
Saving checkpoint... 
Iteration: 973901214, states[0] = -94.875160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985731315, states[0] = -94.741041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997597931, states[0] = -17.998060, states[40]= 0.001143
Saving checkpoint... 
Iteration: 1009425151, states[0] = -94.881726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021241543, states[0] = -94.756971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033081954, states[0] = -4.271059, states[40]= 0.003608
Saving checkpoint... 
Iteration: 1044929852, states[0] = -94.882834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056776240, states[0] = -94.800406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068628561, states[0] = -48.073600, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1080353074, states[0] = -94.856326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091923361, states[0] = -94.881238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103192924, states[0] = -94.667124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114938841, states[0] = -94.884816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126785682, states[0] = -94.809772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138702231, states[0] = -94.687066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150517961, states[0] = 22.680193, states[40]= 0.013134
Saving checkpoint... 
Iteration: 1162370889, states[0] = -94.864251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174215253, states[0] = -94.712682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186028680, states[0] = 19.703600, states[40]= 0.006850
Saving checkpoint... 
Iteration: 1197888583, states[0] = -94.870911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209775036, states[0] = -94.799057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221628245, states[0] = -47.729681, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1233462538, states[0] = -94.889319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245326970, states[0] = -94.841769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257193076, states[0] = -94.667388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269000456, states[0] = -35.497010, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1280869674, states[0] = -94.863685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292696393, states[0] = -94.674718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304544398, states[0] = 14.006602, states[40]= 0.005383
Saving checkpoint... 
Iteration: 1316409164, states[0] = -94.877327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328262854, states[0] = -94.785275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340112982, states[0] = -32.273577, states[40]= 0.000367
Saving checkpoint... 
Iteration: 1351956227, states[0] = -94.888137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363818816, states[0] = -94.836373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375654333, states[0] = -80.348177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387520320, states[0] = 22.100647, states[40]= 0.010392
Saving checkpoint... 
Iteration: 1399386545, states[0] = -94.870088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411219085, states[0] = -94.719647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423065012, states[0] = 5.275430, states[40]= 0.004874
Saving checkpoint... 
Iteration: 1434743426, states[0] = -94.759511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446577875, states[0] = -1.575355, states[40]= 0.004106
Saving checkpoint... 
Iteration: 1458446154, states[0] = -94.886149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470323624, states[0] = -94.839510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482137066, states[0] = -57.557721, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1494011174, states[0] = 24.439800, states[40]= 0.041515
Saving checkpoint... 
Iteration: 1505810589, states[0] = -46.712335, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1517584496, states[0] = -95.011308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529291761, states[0] = -95.040333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541064446, states[0] = -95.159451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552823512, states[0] = 20.406629, states[40]= 0.009628
Saving checkpoint... 
Iteration: 1564630581, states[0] = -77.273386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576366696, states[0] = -95.004708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588178491, states[0] = -95.190596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599907398, states[0] = 27.699438, states[40]= 0.088141
Saving checkpoint... 
Iteration: 1611659620, states[0] = 1.760247, states[40]= 0.005143
Saving checkpoint... 
Iteration: 1623437570, states[0] = -89.210118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635235888, states[0] = -95.149068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646952669, states[0] = -95.169941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658721891, states[0] = 20.893840, states[40]= 0.010528
Saving checkpoint... 
Iteration: 1670492545, states[0] = -29.969095, states[40]= 0.000464
Saving checkpoint... 
Iteration: 1682257149, states[0] = -94.964361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694032847, states[0] = -95.145873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705767483, states[0] = -95.185809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717518726, states[0] = 22.064928, states[40]= 0.013545
Saving checkpoint... 
Iteration: 1729294135, states[0] = -31.709723, states[40]= 0.000386
Saving checkpoint... 
Iteration: 1741074438, states[0] = -95.033693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752826232, states[0] = -95.136482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764500604, states[0] = -95.092461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776280753, states[0] = -95.197596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788014235, states[0] = 23.670907, states[40]= 0.024328
Saving checkpoint... 
Iteration: 1799392132, states[0] = -95.206406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810740051, states[0] = -94.809415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821936741, states[0] = -94.926871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833652294, states[0] = -80.249767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845399909, states[0] = -94.896123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857151197, states[0] = -76.977618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868835260, states[0] = -94.857419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880578422, states[0] = -2.142731, states[40]= 0.004017
Saving checkpoint... 
Iteration: 1892334599, states[0] = -94.851534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904081173, states[0] = -3.853092, states[40]= 0.003695
Saving checkpoint... 
Iteration: 1915811925, states[0] = -94.833975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927545032, states[0] = 13.729913, states[40]= 0.005360
Saving checkpoint... 
Iteration: 1939340907, states[0] = -94.850932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951090179, states[0] = -10.875740, states[40]= 0.002196
Saving checkpoint... 
Iteration: 1962834182, states[0] = -94.846414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974596673, states[0] = -16.833324, states[40]= 0.001262
Saving checkpoint... 
Iteration: 1986089460, states[0] = -10.217606, states[40]= 0.002330
Saving checkpoint... 
Iteration: 1997115408, states[0] = -34.622830, states[40]= 0.000274
Saving checkpoint... 
Iteration: 2008845671, states[0] = -94.852221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020602174, states[0] = -22.020380, states[40]= 0.000861
Saving checkpoint... 
Iteration: 2032375107, states[0] = -94.865519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044124920, states[0] = -44.172807, states[40]= 0.000070
Saving checkpoint... 
Iteration: 2055863423, states[0] = -94.860588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067585322, states[0] = -6.775677, states[40]= 0.003075
Saving checkpoint... 
Iteration: 2079326025, states[0] = -94.840694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091057865, states[0] = 8.482152, states[40]= 0.005053
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.770082
 - CaMKt in component CaMK (millimolar): 0.006759
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.708201
 - nass in component intracellular_ions (millimolar): 6.708260
 - ki in component intracellular_ions (millimolar): 145.272172
 - kss in component intracellular_ions (millimolar): 145.272153
 - cansr in component intracellular_ions (millimolar): 1.303686
 - cajsr in component intracellular_ions (millimolar): 1.266158
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003667
 - hf in component INa (dimensionless): 0.877696
 - hs in component INa (dimensionless): 0.877691
 - j in component INa (dimensionless): 0.877660
 - hsp in component INa (dimensionless): 0.721500
 - jp in component INa (dimensionless): 0.877640
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.706497
 - hLp in component INaL (dimensionless): 0.448228
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.620947
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.695164
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933975
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001584
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.344335
 - xs1 in component IKs (dimensionless): 0.241323
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997372
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:49:50 (84921): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge