𝕏

Task 56358623

Name HuVeMOp_20240705214718056723_ORdGradInc_k_27-TESZT_Block_K1_75-conf_401_0
Workunit 26767945
Created 5 Jul 2024, 19:48:16 UTC
Sent 6 Jul 2024, 3:01:12 UTC
Report deadline 9 Jul 2024, 3:01:12 UTC
Received 6 Jul 2024, 18:33:26 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241612
Run time 3 hours 5 min 46 sec
CPU time 2 hours 59 min 58 sec
Validate state Valid
Credit 45.53
Device peak FLOPS 3.27 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240705214718056723_ORdGradInc_k_27-TESZT_Block_K1_75-conf_401.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240705214718056723_ORdGradInc_k_27-TESZT_Block_K1_75-conf_401_0_r1017130871_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240705214718056723_ORdGradInc_k_27-TESZT_Block_K1_75-conf_401_0_r1017130871_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.406551
     * GNaL_b in INaL: 0.005772
     * Gto_b in Ito: 0.084512
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031991
     * GKs_b in IKs: 0.001937
     * GK1_b in IK1: 0.041154
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.560764
     * GKb_b in IKb: 0.003796
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033531
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8189725, states[0] = -82.355385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16785800, states[0] = -90.982585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25129450, states[0] = -42.586792, states[40]= 0.000214
Saving checkpoint... 
Iteration: 34034254, states[0] = 23.270401, states[40]= 0.001577
Saving checkpoint... 
Iteration: 42486930, states[0] = -91.414912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51038653, states[0] = 21.844497, states[40]= 0.001746
Saving checkpoint... 
Iteration: 59392217, states[0] = -91.193547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67878197, states[0] = -91.126943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76440373, states[0] = -91.251822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84773289, states[0] = -90.126251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93351524, states[0] = -90.975237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102064967, states[0] = 11.404790, states[40]= 0.003643
Saving checkpoint... 
Iteration: 110839450, states[0] = -90.895250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119441207, states[0] = -91.205936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127996508, states[0] = -91.256423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136447493, states[0] = -91.207025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144914107, states[0] = -91.147385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153189717, states[0] = -77.570717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 161503860, states[0] = 33.106332, states[40]= 0.354017
Saving checkpoint... 
Iteration: 169685497, states[0] = -76.075002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177928026, states[0] = -91.168127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186294706, states[0] = -90.474440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195045477, states[0] = 19.490858, states[40]= 0.002191
Saving checkpoint... 
Iteration: 203932398, states[0] = -91.173401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212539104, states[0] = 21.869339, states[40]= 0.001805
Saving checkpoint... 
Iteration: 220694921, states[0] = -79.239139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228804221, states[0] = -90.589861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237197651, states[0] = -80.072389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245673142, states[0] = -71.075937, states[40]= 0.000002
Saving checkpoint... 
Iteration: 253899368, states[0] = -91.102819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262120948, states[0] = -32.460426, states[40]= 0.000739
Saving checkpoint... 
Iteration: 270468964, states[0] = -91.218621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278880648, states[0] = -91.047992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287481496, states[0] = -91.229395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296002113, states[0] = 41.760932, states[40]= 0.468882
Saving checkpoint... 
Iteration: 304376980, states[0] = -91.035435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313054860, states[0] = 15.801250, states[40]= 0.002880
Saving checkpoint... 
Iteration: 321538814, states[0] = 21.976628, states[40]= 0.001790
Saving checkpoint... 
Iteration: 329875721, states[0] = -91.030887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337920319, states[0] = -91.149081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346452066, states[0] = -91.199278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354900915, states[0] = -91.105803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363491337, states[0] = -91.235964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371884389, states[0] = -91.059273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380760974, states[0] = -89.625287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389255259, states[0] = -89.350683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397922305, states[0] = -91.152578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406641480, states[0] = -51.219700, states[40]= 0.000063
Saving checkpoint... 
Iteration: 415142646, states[0] = -52.193811, states[40]= 0.000054
Saving checkpoint... 
Iteration: 423656153, states[0] = -62.042242, states[40]= 0.000010
Saving checkpoint... 
Iteration: 432030390, states[0] = 24.845866, states[40]= 0.001442
Saving checkpoint... 
Iteration: 440956628, states[0] = -91.204319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449692565, states[0] = -78.481174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458055899, states[0] = 15.376421, states[40]= 0.002961
Saving checkpoint... 
Iteration: 466496403, states[0] = -91.238633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474879690, states[0] = -91.043632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483265837, states[0] = -89.815457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491730815, states[0] = -87.194109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500152144, states[0] = -59.399351, states[40]= 0.000016
Saving checkpoint... 
Iteration: 508800908, states[0] = -90.549244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517252870, states[0] = -89.215844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525463954, states[0] = -91.212034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533643403, states[0] = -52.815958, states[40]= 0.000049
Saving checkpoint... 
Iteration: 542519451, states[0] = 27.525156, states[40]= 0.002888
Saving checkpoint... 
Iteration: 551364591, states[0] = -90.987886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559818738, states[0] = -90.724606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568317025, states[0] = -90.710368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576757430, states[0] = -89.460967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585068447, states[0] = 9.854920, states[40]= 0.003889
Saving checkpoint... 
Iteration: 593452113, states[0] = -91.198110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601773446, states[0] = -90.052295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610698146, states[0] = -80.214034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619417544, states[0] = -91.142154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627963793, states[0] = -91.211372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636311522, states[0] = -90.661050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644760919, states[0] = -89.621290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653126795, states[0] = -37.958687, states[40]= 0.000415
Saving checkpoint... 
Iteration: 661910462, states[0] = -91.126907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670586830, states[0] = -0.590123, states[40]= 0.004236
Saving checkpoint... 
Iteration: 678864036, states[0] = -90.985008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687325940, states[0] = -90.778974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695752847, states[0] = -89.213347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704167848, states[0] = -68.579637, states[40]= 0.000003
Saving checkpoint... 
Iteration: 712604150, states[0] = -16.052705, states[40]= 0.001523
Saving checkpoint... 
Iteration: 721112188, states[0] = -24.050181, states[40]= 0.001101
Saving checkpoint... 
Iteration: 729780413, states[0] = -90.219837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738023996, states[0] = 26.626327, states[40]= 0.001569
Saving checkpoint... 
Iteration: 746315174, states[0] = -90.693590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754725894, states[0] = -86.483525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763079297, states[0] = 4.188783, states[40]= 0.004372
Saving checkpoint... 
Iteration: 771293642, states[0] = -90.452469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779639135, states[0] = -49.207948, states[40]= 0.000087
Saving checkpoint... 
Iteration: 787769498, states[0] = -89.936150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795991305, states[0] = -91.233841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804193925, states[0] = -78.916028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812567304, states[0] = 10.394987, states[40]= 0.003814
Saving checkpoint... 
Iteration: 821045963, states[0] = 19.309708, states[40]= 0.002225
Saving checkpoint... 
Iteration: 829713637, states[0] = -84.200100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838419298, states[0] = -91.144608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847127600, states[0] = -38.709333, states[40]= 0.000379
Saving checkpoint... 
Iteration: 855956292, states[0] = -91.201924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864697840, states[0] = -80.121350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873426767, states[0] = -91.158506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881770734, states[0] = -89.973402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890088141, states[0] = -1.527848, states[40]= 0.004140
Saving checkpoint... 
Iteration: 898825948, states[0] = -90.777971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907730597, states[0] = -87.161997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916242943, states[0] = -88.502728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924695711, states[0] = -79.474899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933334003, states[0] = -90.831750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941924376, states[0] = -91.153825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950448485, states[0] = -91.191721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958659011, states[0] = -63.789065, states[40]= 0.000007
Saving checkpoint... 
Iteration: 966885325, states[0] = -91.059264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975099756, states[0] = -11.639554, states[40]= 0.002219
Saving checkpoint... 
Iteration: 983366318, states[0] = -90.992677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991725815, states[0] = -86.469445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999972607, states[0] = -91.218228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008261136, states[0] = -89.628386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016232673, states[0] = -87.429353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024410620, states[0] = -91.125504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032946667, states[0] = -91.188890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042156118, states[0] = -62.017300, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1050986627, states[0] = -91.229391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059695901, states[0] = -79.532602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068165293, states[0] = -67.281048, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1076546293, states[0] = 19.183615, states[40]= 0.002247
Saving checkpoint... 
Iteration: 1084619823, states[0] = -31.386789, states[40]= 0.000807
Saving checkpoint... 
Iteration: 1092770127, states[0] = -89.953832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100868648, states[0] = -91.001174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108890601, states[0] = -91.074304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116843030, states[0] = -90.883650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125158290, states[0] = -63.357070, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1133380605, states[0] = -91.043441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141478153, states[0] = -91.222388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149705275, states[0] = -82.196943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157746508, states[0] = -88.787898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165811005, states[0] = -90.653458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173958982, states[0] = -91.203498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182078755, states[0] = 4.501108, states[40]= 0.004362
Saving checkpoint... 
Iteration: 1190309265, states[0] = -90.636472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198463052, states[0] = -91.207844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206637942, states[0] = -48.160269, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1214490544, states[0] = -91.231324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222677162, states[0] = -72.804420, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230907573, states[0] = -91.117602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239115053, states[0] = -26.822415, states[40]= 0.001033
Saving checkpoint... 
Iteration: 1247247814, states[0] = -88.882989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255350015, states[0] = -90.919243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263373161, states[0] = -91.017177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271320577, states[0] = -90.735757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279316580, states[0] = -90.703004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287433729, states[0] = -91.168399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295365711, states[0] = -90.988741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303638808, states[0] = -48.920418, states[40]= 0.000091
Saving checkpoint... 
Iteration: 1311714075, states[0] = -84.291350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319792881, states[0] = -90.438470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327940767, states[0] = -91.179117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336186409, states[0] = -76.375257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344506120, states[0] = 28.897634, states[40]= 0.171304
Saving checkpoint... 
Iteration: 1352328241, states[0] = -90.791804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360639266, states[0] = -49.319322, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1368806756, states[0] = -90.610095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376763595, states[0] = -89.726467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384859916, states[0] = -90.964286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393148046, states[0] = -56.451136, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1401457099, states[0] = -91.200243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409701732, states[0] = -81.239811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417934040, states[0] = -91.168274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425826404, states[0] = -90.778584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434197482, states[0] = -80.010525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442369512, states[0] = -91.002798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450522908, states[0] = 26.876311, states[40]= 0.001713
Saving checkpoint... 
Iteration: 1458687188, states[0] = -76.651725, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466941615, states[0] = -91.179691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475134376, states[0] = -44.960299, states[40]= 0.000164
Saving checkpoint... 
Iteration: 1483489515, states[0] = -91.229335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491697378, states[0] = -79.978931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499777602, states[0] = -90.152379, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -91.111620
 - CaMKt in component CaMK (millimolar): 0.012349
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.602962
 - nass in component intracellular_ions (millimolar): 6.603056
 - ki in component intracellular_ions (millimolar): 145.284087
 - kss in component intracellular_ions (millimolar): 145.284067
 - cansr in component intracellular_ions (millimolar): 1.637929
 - cajsr in component intracellular_ions (millimolar): 1.595536
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.005303
 - hf in component INa (dimensionless): 0.797325
 - hs in component INa (dimensionless): 0.797288
 - j in component INa (dimensionless): 0.797026
 - hsp in component INa (dimensionless): 0.586656
 - jp in component INa (dimensionless): 0.796818
 - mL in component INaL (dimensionless): 0.000102
 - hL in component INaL (dimensionless): 0.584127
 - hLp in component INaL (dimensionless): 0.308331
 - a in component Ito (dimensionless): 0.000805
 - iF in component Ito (dimensionless): 0.999747
 - iS in component Ito (dimensionless): 0.574578
 - ap in component Ito (dimensionless): 0.000410
 - iFp in component Ito (dimensionless): 0.999747
 - iSp in component Ito (dimensionless): 0.629499
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.915415
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999833
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002919
 - xrf in component IKr (dimensionless): 0.000005
 - xrs in component IKr (dimensionless): 0.442090
 - xs1 in component IKs (dimensionless): 0.270241
 - xs2 in component IKs (dimensionless): 0.000134
 - xk1 in component IK1 (dimensionless): 0.998170
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:45:12 (24883): called boinc_finish(0)

</stderr_txt>
]]>


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