𝕏

Task 56294406

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294_0
Workunit 26738596
Created 4 Jul 2024, 22:49:15 UTC
Sent 5 Jul 2024, 19:05:39 UTC
Report deadline 8 Jul 2024, 19:05:39 UTC
Received 8 Jul 2024, 3:06:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222979
Run time 42 min 35 sec
CPU time 30 min 4 sec
Validate state Valid
Credit 42.76
Device peak FLOPS 3.64 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.91 MB
Peak swap size 391.75 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294_0_r1524078049_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294_0_r1524078049_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.604339
     * GNaL_b in INaL: 0.005886
     * Gto_b in Ito: 0.084983
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031909
     * GKs_b in IKs: 0.001933
     * GK1_b in IK1: 0.164460
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.380196
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032213
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 30779748, states[0] = -87.374511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55134934, states[0] = -87.735226, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294_0_r1524078049_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294_0_r1524078049_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.604339
     * GNaL_b in INaL: 0.005886
     * Gto_b in Ito: 0.084983
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031909
     * GKs_b in IKs: 0.001933
     * GK1_b in IK1: 0.164460
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.380196
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032213
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 55134934
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.735226 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 70024154, states[0] = 12.418485, states[40]= 0.007956


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294_0_r1524078049_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294_0_r1524078049_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.604339
     * GNaL_b in INaL: 0.005886
     * Gto_b in Ito: 0.084983
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031909
     * GKs_b in IKs: 0.001933
     * GK1_b in IK1: 0.164460
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.380196
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032213
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 70024154
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 12.418485 (After loading)
 - states[40]: 0.007956 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 85729577, states[0] = -31.565506, states[40]= 0.000444
Saving checkpoint... 
Iteration: 101479941, states[0] = -87.795509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115007254, states[0] = 19.025474, states[40]= 0.012457
Saving checkpoint... 
Iteration: 130767220, states[0] = -87.134718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145526021, states[0] = 5.845804, states[40]= 0.007007
Saving checkpoint... 
Iteration: 162749391, states[0] = -72.327684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 176793603, states[0] = -87.757128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191884105, states[0] = -29.533023, states[40]= 0.000545
Saving checkpoint... 
Iteration: 209100546, states[0] = -87.619942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226202897, states[0] = -13.843821, states[40]= 0.002300
Saving checkpoint... 
Iteration: 242677090, states[0] = 10.086427, states[40]= 0.007579
Saving checkpoint... 
Iteration: 257215042, states[0] = -35.257291, states[40]= 0.000293
Saving checkpoint... 
Iteration: 272699354, states[0] = -15.408797, states[40]= 0.001972
Saving checkpoint... 
Iteration: 288691497, states[0] = -6.936071, states[40]= 0.004191
Saving checkpoint... 
Iteration: 306666494, states[0] = 12.788030, states[40]= 0.008034
Saving checkpoint... 
Iteration: 322428089, states[0] = -87.679420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339600943, states[0] = -87.719622, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294_0_r1524078049_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_294_0_r1524078049_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.604339
     * GNaL_b in INaL: 0.005886
     * Gto_b in Ito: 0.084983
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031909
     * GKs_b in IKs: 0.001933
     * GK1_b in IK1: 0.164460
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.380196
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032213
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 339600943
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.719622 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 356238604, states[0] = -84.668559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379541966, states[0] = -43.295287, states[40]= 0.000102
Saving checkpoint... 
Iteration: 399596800, states[0] = -87.727169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419924860, states[0] = -87.713472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439945582, states[0] = -87.794881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463553713, states[0] = -74.226061, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486479951, states[0] = 13.929551, states[40]= 0.008297
Saving checkpoint... 
Iteration: 507320860, states[0] = 7.580994, states[40]= 0.007239
Saving checkpoint... 
Iteration: 523445636, states[0] = -87.818666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541162802, states[0] = -2.925151, states[40]= 0.005337
Saving checkpoint... 
Iteration: 562600757, states[0] = -87.797158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583354051, states[0] = -42.097686, states[40]= 0.000121
Saving checkpoint... 
Iteration: 600075038, states[0] = -87.719910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623792379, states[0] = 17.787431, states[40]= 0.010406
Saving checkpoint... 
Iteration: 645028066, states[0] = -61.634898, states[40]= 0.000006
Saving checkpoint... 
Iteration: 667645382, states[0] = 1.763379, states[40]= 0.006374
Saving checkpoint... 
Iteration: 688686785, states[0] = -56.216386, states[40]= 0.000015
Saving checkpoint... 
Iteration: 710869138, states[0] = -84.099339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727607118, states[0] = 21.241936, states[40]= 0.025201
Saving checkpoint... 
Iteration: 746762569, states[0] = 30.396463, states[40]= 0.125751
Saving checkpoint... 
Iteration: 768013678, states[0] = -58.436390, states[40]= 0.000011
Saving checkpoint... 
Iteration: 788964629, states[0] = 3.459243, states[40]= 0.006660
Saving checkpoint... 
Iteration: 807950892, states[0] = 12.042608, states[40]= 0.007891
Saving checkpoint... 
Iteration: 827707378, states[0] = -87.648140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849438522, states[0] = 16.769010, states[40]= 0.009498
Saving checkpoint... 
Iteration: 868919329, states[0] = 25.454490, states[40]= 0.100068
Saving checkpoint... 
Iteration: 888898373, states[0] = -87.787209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912294793, states[0] = -5.707934, states[40]= 0.004556
Saving checkpoint... 
Iteration: 932350769, states[0] = -86.407559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941765524, states[0] = 15.210167, states[40]= 0.008699
Saving checkpoint... 
Iteration: 962237538, states[0] = -27.630160, states[40]= 0.000006
Saving checkpoint... 
Iteration: 985067095, states[0] = -87.820606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005477275, states[0] = -40.397732, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1023787185, states[0] = -10.236766, states[40]= 0.003220
Saving checkpoint... 
Iteration: 1041465301, states[0] = -28.830039, states[40]= 0.000582
Saving checkpoint... 
Iteration: 1060970069, states[0] = -38.112628, states[40]= 0.000206
Saving checkpoint... 
Iteration: 1083641315, states[0] = -47.634292, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1103382587, states[0] = -87.804019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125553909, states[0] = -87.822825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141045013, states[0] = -87.802572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165764644, states[0] = -0.495859, states[40]= 0.005923
Saving checkpoint... 
Iteration: 1187813978, states[0] = -73.109107, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1206691652, states[0] = -87.759570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230654626, states[0] = -86.531677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250904155, states[0] = 13.540406, states[40]= 0.008200
Saving checkpoint... 
Iteration: 1271325806, states[0] = -87.577203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290758819, states[0] = -8.042976, states[40]= 0.003860
Saving checkpoint... 
Iteration: 1308699827, states[0] = -87.816066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329712939, states[0] = 21.481246, states[40]= 0.028180
Saving checkpoint... 
Iteration: 1351502087, states[0] = -87.727936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375897476, states[0] = 9.825203, states[40]= 0.007541
Saving checkpoint... 
Iteration: 1396733291, states[0] = 6.554843, states[40]= 0.007103
Saving checkpoint... 
Iteration: 1415297706, states[0] = -83.110677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434741098, states[0] = -4.024131, states[40]= 0.005040
Saving checkpoint... 
Iteration: 1457506972, states[0] = -87.782684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472631083, states[0] = -86.728106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496489117, states[0] = -87.733705, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.698321
 - CaMKt in component CaMK (millimolar): 0.042402
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.007772
 - nass in component intracellular_ions (millimolar): 7.007920
 - ki in component intracellular_ions (millimolar): 144.912575
 - kss in component intracellular_ions (millimolar): 144.912543
 - cansr in component intracellular_ions (millimolar): 1.619844
 - cajsr in component intracellular_ions (millimolar): 1.187783
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007478
 - hf in component INa (dimensionless): 0.691862
 - hs in component INa (dimensionless): 0.691625
 - j in component INa (dimensionless): 0.681101
 - hsp in component INa (dimensionless): 0.446650
 - jp in component INa (dimensionless): 0.654611
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.292936
 - hLp in component INaL (dimensionless): 0.136131
 - a in component Ito (dimensionless): 0.001013
 - iF in component Ito (dimensionless): 0.999539
 - iS in component Ito (dimensionless): 0.175681
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999539
 - iSp in component Ito (dimensionless): 0.212589
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804089
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966823
 - jca in component ICaL (dimensionless): 0.947954
 - ffp in component ICaL (dimensionless): 0.999863
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009464
 - xrf in component IKr (dimensionless): 0.028680
 - xrs in component IKr (dimensionless): 0.787448
 - xs1 in component IKs (dimensionless): 0.458909
 - xs2 in component IKs (dimensionless): 0.001187
 - xk1 in component IK1 (dimensionless): 0.996812
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:06:23 (10324): called boinc_finish(0)

</stderr_txt>
]]>