𝕏

Task 56291268

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_500-conf_391_0
Workunit 26737028
Created 4 Jul 2024, 22:47:46 UTC
Sent 5 Jul 2024, 18:48:02 UTC
Report deadline 8 Jul 2024, 18:48:02 UTC
Received 6 Jul 2024, 7:10:55 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241714
Run time 1 hours 23 min 47 sec
CPU time 1 hours 19 min 14 sec
Validate state Valid
Credit 44.26
Device peak FLOPS 4.33 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.30 MB
Peak swap size 1.41 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_500-conf_391.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_500-conf_391_0_r712230883_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_500-conf_391_0_r712230883_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.554564
     * GNaL_b in INaL: 0.005859
     * Gto_b in Ito: 0.084558
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031893
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.162697
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.433363
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031943
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9736897, states[0] = -87.482424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19409499, states[0] = -87.300524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28869981, states[0] = -78.270517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38413160, states[0] = -87.283755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48003205, states[0] = 32.772764, states[40]= 0.132079
Saving checkpoint... 
Iteration: 57338380, states[0] = -34.430011, states[40]= 0.000270
Saving checkpoint... 
Iteration: 66660803, states[0] = -87.264086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76477478, states[0] = -87.402274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86131080, states[0] = -86.385823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96078848, states[0] = -22.588486, states[40]= 0.000858
Saving checkpoint... 
Iteration: 105674223, states[0] = -87.295359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115248821, states[0] = -87.425293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124973177, states[0] = -87.391719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134702042, states[0] = -87.355780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144521926, states[0] = 20.192214, states[40]= 0.008903
Saving checkpoint... 
Iteration: 153465807, states[0] = -87.379585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163214324, states[0] = -87.377038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172998029, states[0] = -87.423126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182389287, states[0] = -87.116821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191373113, states[0] = -80.996561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200341633, states[0] = -37.938532, states[40]= 0.000172
Saving checkpoint... 
Iteration: 209380585, states[0] = -86.220952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218598753, states[0] = -46.654433, states[40]= 0.000049
Saving checkpoint... 
Iteration: 227359422, states[0] = -60.529839, states[40]= 0.000005
Saving checkpoint... 
Iteration: 236549736, states[0] = 5.796938, states[40]= 0.005626
Saving checkpoint... 
Iteration: 245631211, states[0] = -86.376127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255202719, states[0] = -87.356200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264987019, states[0] = -87.409650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274567691, states[0] = -9.125048, states[40]= 0.002970
Saving checkpoint... 
Iteration: 283582144, states[0] = -26.495106, states[40]= 0.000618
Saving checkpoint... 
Iteration: 292998504, states[0] = -87.423334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302437729, states[0] = -87.325432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311489570, states[0] = -87.412798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320938207, states[0] = -87.326471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329939216, states[0] = -87.328680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338762800, states[0] = 22.890732, states[40]= 0.025958
Saving checkpoint... 
Iteration: 347227674, states[0] = -87.396996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356415253, states[0] = -87.269130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366043554, states[0] = 9.577905, states[40]= 0.005919
Saving checkpoint... 
Iteration: 375512877, states[0] = 22.872375, states[40]= 0.025580
Saving checkpoint... 
Iteration: 385024111, states[0] = 19.355769, states[40]= 0.008045
Saving checkpoint... 
Iteration: 394575037, states[0] = -17.820174, states[40]= 0.001313
Saving checkpoint... 
Iteration: 404322679, states[0] = -14.949263, states[40]= 0.001736
Saving checkpoint... 
Iteration: 413790342, states[0] = 11.413991, states[40]= 0.006073
Saving checkpoint... 
Iteration: 423711902, states[0] = -87.372432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433606128, states[0] = -56.088288, states[40]= 0.000011
Saving checkpoint... 
Iteration: 443282587, states[0] = 15.521509, states[40]= 0.006598
Saving checkpoint... 
Iteration: 453190063, states[0] = -87.330396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463028973, states[0] = 17.255348, states[40]= 0.007014
Saving checkpoint... 
Iteration: 472731598, states[0] = -87.402306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482172126, states[0] = -87.287566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491835241, states[0] = -30.241092, states[40]= 0.000434
Saving checkpoint... 
Iteration: 501520916, states[0] = 20.560392, states[40]= 0.009459
Saving checkpoint... 
Iteration: 510544746, states[0] = 8.875819, states[40]= 0.005864
Saving checkpoint... 
Iteration: 519745884, states[0] = -87.420125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528882252, states[0] = -86.582866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538704344, states[0] = -87.358928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548392828, states[0] = -87.175414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556332280, states[0] = -26.659515, states[40]= 0.000609
Saving checkpoint... 
Iteration: 565528074, states[0] = 17.665320, states[40]= 0.007151
Saving checkpoint... 
Iteration: 570560185, states[0] = -1.798189, states[40]= 0.004660
Saving checkpoint... 
Iteration: 577765942, states[0] = 22.105544, states[40]= 0.015441
Saving checkpoint... 
Iteration: 587533489, states[0] = 15.069068, states[40]= 0.006518
Saving checkpoint... 
Iteration: 597226653, states[0] = -87.395286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606954337, states[0] = -87.358845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616602624, states[0] = -51.541178, states[40]= 0.000023
Saving checkpoint... 
Iteration: 626388215, states[0] = -87.085032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635931613, states[0] = -87.311042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645514972, states[0] = 22.359720, states[40]= 0.017803
Saving checkpoint... 
Iteration: 655281617, states[0] = 15.999741, states[40]= 0.006693
Saving checkpoint... 
Iteration: 665139469, states[0] = -87.120464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674703618, states[0] = -87.357441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684259306, states[0] = 23.841279, states[40]= 0.054159
Saving checkpoint... 
Iteration: 693595344, states[0] = -42.439421, states[40]= 0.000091
Saving checkpoint... 
Iteration: 703217521, states[0] = -87.381380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713142914, states[0] = -87.176165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723022637, states[0] = 19.930748, states[40]= 0.008581
Saving checkpoint... 
Iteration: 733012682, states[0] = 22.918960, states[40]= 0.026551
Saving checkpoint... 
Iteration: 742840107, states[0] = -36.096308, states[40]= 0.000219
Saving checkpoint... 
Iteration: 752505679, states[0] = 26.439190, states[40]= 0.114719
Saving checkpoint... 
Iteration: 762155535, states[0] = -87.239986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771871680, states[0] = -79.078726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781487373, states[0] = -87.409565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791228932, states[0] = -87.398313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799842376, states[0] = -38.831287, states[40]= 0.000152
Saving checkpoint... 
Iteration: 808428345, states[0] = -87.302981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816964322, states[0] = -87.376080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826280440, states[0] = 16.567676, states[40]= 0.006824
Saving checkpoint... 
Iteration: 835395904, states[0] = -87.200337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844156067, states[0] = -87.241586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852938247, states[0] = -87.326013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860669367, states[0] = -87.279873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868712716, states[0] = -87.373352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876980571, states[0] = -87.400494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884674405, states[0] = -87.293039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892523633, states[0] = 19.545815, states[40]= 0.008202
Saving checkpoint... 
Iteration: 900556150, states[0] = 1.391483, states[40]= 0.005169
Saving checkpoint... 
Iteration: 907892041, states[0] = -87.165734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915478344, states[0] = -87.397362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923393329, states[0] = -87.180181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931350745, states[0] = -49.152272, states[40]= 0.000033
Saving checkpoint... 
Iteration: 939051263, states[0] = 4.803067, states[40]= 0.005541
Saving checkpoint... 
Iteration: 947207121, states[0] = -87.363563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955305301, states[0] = 2.013981, states[40]= 0.005248
Saving checkpoint... 
Iteration: 963248154, states[0] = -87.422256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971233917, states[0] = -87.404899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979043238, states[0] = 9.762420, states[40]= 0.005933
Saving checkpoint... 
Iteration: 986695839, states[0] = -87.341975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994360018, states[0] = -61.353654, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1002342426, states[0] = -38.891418, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1010115253, states[0] = -69.060844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018002485, states[0] = 36.304036, states[40]= 0.111876
Saving checkpoint... 
Iteration: 1025919905, states[0] = -87.281144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033797060, states[0] = 7.478254, states[40]= 0.005759
Saving checkpoint... 
Iteration: 1041365359, states[0] = -69.225558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1049108355, states[0] = -59.065290, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1056747381, states[0] = -87.421289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064779907, states[0] = 16.820305, states[40]= 0.006889
Saving checkpoint... 
Iteration: 1072691281, states[0] = -87.332383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080685889, states[0] = -87.320502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088781793, states[0] = 15.913834, states[40]= 0.006675
Saving checkpoint... 
Iteration: 1096904657, states[0] = -87.236815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105309027, states[0] = -0.838424, states[40]= 0.004832
Saving checkpoint... 
Iteration: 1113588452, states[0] = -34.105706, states[40]= 0.000281
Saving checkpoint... 
Iteration: 1121903244, states[0] = -87.232092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130112620, states[0] = -65.078320, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1138096530, states[0] = -43.894845, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1146262163, states[0] = 23.043330, states[40]= 0.029398
Saving checkpoint... 
Iteration: 1154831041, states[0] = -25.153932, states[40]= 0.000693
Saving checkpoint... 
Iteration: 1163725798, states[0] = -87.393477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173078261, states[0] = -21.764355, states[40]= 0.000920
Saving checkpoint... 
Iteration: 1182590680, states[0] = -36.785251, states[40]= 0.000201
Saving checkpoint... 
Iteration: 1192153322, states[0] = -87.232285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201510071, states[0] = 23.591781, states[40]= 0.045718
Saving checkpoint... 
Iteration: 1210992944, states[0] = -87.415977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220597780, states[0] = -45.439976, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1229013761, states[0] = 22.660450, states[40]= 0.021759
Saving checkpoint... 
Iteration: 1237745574, states[0] = -87.419037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246750480, states[0] = -6.794362, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1256481392, states[0] = -87.401228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266013762, states[0] = 22.660215, states[40]= 0.021755
Saving checkpoint... 
Iteration: 1275237055, states[0] = -87.408658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285096012, states[0] = -43.257469, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1295099712, states[0] = -47.850833, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1305045753, states[0] = 8.273752, states[40]= 0.005819
Saving checkpoint... 
Iteration: 1314877695, states[0] = -85.065268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324617929, states[0] = -73.295063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1334275899, states[0] = 18.618167, states[40]= 0.007568
Saving checkpoint... 
Iteration: 1344133659, states[0] = -86.782599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353921657, states[0] = -87.285444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363450814, states[0] = -87.351429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372002067, states[0] = 38.602473, states[40]= 0.094710
Saving checkpoint... 
Iteration: 1381442794, states[0] = -87.335275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390483503, states[0] = -87.403924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399535243, states[0] = 14.168869, states[40]= 0.006380
Saving checkpoint... 
Iteration: 1408914908, states[0] = -87.267083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418391263, states[0] = -87.154239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427807251, states[0] = 0.561922, states[40]= 0.005054
Saving checkpoint... 
Iteration: 1437113159, states[0] = -65.874626, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1446872752, states[0] = -80.529939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456076367, states[0] = -19.446485, states[40]= 0.001128
Saving checkpoint... 
Iteration: 1465609926, states[0] = -61.224236, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1474956821, states[0] = -87.362485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483959009, states[0] = -87.366360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493149270, states[0] = -87.216787, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.299515
 - CaMKt in component CaMK (millimolar): 0.019359
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.743325
 - nass in component intracellular_ions (millimolar): 6.743425
 - ki in component intracellular_ions (millimolar): 145.214204
 - kss in component intracellular_ions (millimolar): 145.214177
 - cansr in component intracellular_ions (millimolar): 1.424260
 - cajsr in component intracellular_ions (millimolar): 1.207024
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007784
 - hf in component INa (dimensionless): 0.677717
 - hs in component INa (dimensionless): 0.677615
 - j in component INa (dimensionless): 0.676916
 - hsp in component INa (dimensionless): 0.431203
 - jp in component INa (dimensionless): 0.674973
 - mL in component INaL (dimensionless): 0.000210
 - hL in component INaL (dimensionless): 0.386954
 - hLp in component INaL (dimensionless): 0.181297
 - a in component Ito (dimensionless): 0.001041
 - iF in component Ito (dimensionless): 0.999506
 - iS in component Ito (dimensionless): 0.293301
 - ap in component Ito (dimensionless): 0.000530
 - iFp in component Ito (dimensionless): 0.999506
 - iSp in component Ito (dimensionless): 0.340949
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.857743
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991062
 - jca in component ICaL (dimensionless): 0.991401
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004188
 - xrf in component IKr (dimensionless): 0.001746
 - xrs in component IKr (dimensionless): 0.673430
 - xs1 in component IKs (dimensionless): 0.383232
 - xs2 in component IKs (dimensionless): 0.000214
 - xk1 in component IK1 (dimensionless): 0.996910
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:38:11 (15340): called boinc_finish(0)

</stderr_txt>
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