𝕏

Task 56276864

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Coppini_2000-conf_178_0
Workunit 26729876
Created 4 Jul 2024, 22:40:17 UTC
Sent 5 Jul 2024, 17:09:07 UTC
Report deadline 8 Jul 2024, 17:09:07 UTC
Received 7 Jul 2024, 23:17:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222979
Run time 1 hours 6 min 22 sec
CPU time 45 min 5 sec
Validate state Valid
Credit 48.50
Device peak FLOPS 3.64 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.00 MB
Peak swap size 391.75 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Coppini_2000-conf_178.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Coppini_2000-conf_178_0_r2097457768_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Coppini_2000-conf_178_0_r2097457768_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.223741
     * GNaL_b in INaL: 0.005757
     * Gto_b in Ito: 0.084934
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031832
     * GKs_b in IKs: 0.001934
     * GK1_b in IK1: 0.164454
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.444369
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033682
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 14279467, states[0] = -94.578728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30241504, states[0] = -94.396847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43314893, states[0] = -94.540545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58450635, states[0] = -94.646920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72714709, states[0] = -94.681226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86618333, states[0] = -94.672370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99495585, states[0] = -94.649074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117699206, states[0] = -94.671357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132605125, states[0] = -94.664666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144908591, states[0] = -94.668295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159338264, states[0] = -94.540768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177052364, states[0] = 18.891669, states[40]= 0.002758
Saving checkpoint... 
Iteration: 188495675, states[0] = -94.643153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202153240, states[0] = -48.703659, states[40]= 0.000116
Saving checkpoint... 
Iteration: 217533428, states[0] = -94.651885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232443957, states[0] = -94.623613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248683758, states[0] = -94.666837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266298449, states[0] = -94.477302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280652980, states[0] = -94.665352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295144455, states[0] = -40.608028, states[40]= 0.000368
Saving checkpoint... 
Iteration: 311575807, states[0] = -94.658405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328755923, states[0] = -94.667876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344827871, states[0] = -94.667475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361638269, states[0] = -94.664276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377488724, states[0] = -94.640154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392661212, states[0] = -94.665518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407949983, states[0] = -94.664933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426123044, states[0] = -22.203535, states[40]= 0.001348
Saving checkpoint... 
Iteration: 442827754, states[0] = -94.667287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457017591, states[0] = 26.902972, states[40]= 0.004891
Saving checkpoint... 
Iteration: 474553433, states[0] = -94.654777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490157493, states[0] = -52.703884, states[40]= 0.000062
Saving checkpoint... 
Iteration: 505898327, states[0] = -94.665942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523411399, states[0] = -94.605245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539966625, states[0] = -94.664271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555291562, states[0] = -94.463182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570083928, states[0] = 6.300494, states[40]= 0.004493
Saving checkpoint... 
Iteration: 586584467, states[0] = -94.658963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602787339, states[0] = -94.667343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619269266, states[0] = -94.412240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635583103, states[0] = -94.658707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649869842, states[0] = -94.666242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666146601, states[0] = -42.536502, states[40]= 0.000283
Saving checkpoint... 
Iteration: 683684294, states[0] = -94.665929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698776574, states[0] = -94.667199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714238953, states[0] = -94.322396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727430980, states[0] = -94.616111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739806677, states[0] = -94.666961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757605459, states[0] = -94.660909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773587548, states[0] = -94.658981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790126004, states[0] = -24.719918, states[40]= 0.001364
Saving checkpoint... 
Iteration: 804722916, states[0] = -94.666658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818012589, states[0] = 26.816935, states[40]= 0.020816
Saving checkpoint... 
Iteration: 833080372, states[0] = 8.008926, states[40]= 0.004395
Saving checkpoint... 
Iteration: 849415297, states[0] = -94.607045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863907858, states[0] = -94.665073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880883830, states[0] = -94.665546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896839575, states[0] = -94.666285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913157992, states[0] = -53.179605, states[40]= 0.000058
Saving checkpoint... 
Iteration: 929063545, states[0] = 15.017052, states[40]= 0.003514
Saving checkpoint... 
Iteration: 942891428, states[0] = -94.665277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957722768, states[0] = -94.666372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971399734, states[0] = -94.596665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986542031, states[0] = -94.651839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001447367, states[0] = -94.623558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019821168, states[0] = -94.666296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036969600, states[0] = -94.663275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049325728, states[0] = -94.520878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059439777, states[0] = -94.619916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073828389, states[0] = -94.666109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087759988, states[0] = -94.666470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104371121, states[0] = -94.573358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122865066, states[0] = -94.665452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136904224, states[0] = -94.664646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150896644, states[0] = -94.664783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166183920, states[0] = -84.296759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183873203, states[0] = -94.665190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199407968, states[0] = -94.601798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215230247, states[0] = -94.290990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227561493, states[0] = -94.654658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241029661, states[0] = 25.270318, states[40]= 0.001677
Saving checkpoint... 
Iteration: 1253594100, states[0] = -94.658829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267684568, states[0] = -94.664857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285914314, states[0] = -94.664147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304126503, states[0] = -25.141580, states[40]= 0.001362
Saving checkpoint... 
Iteration: 1318814885, states[0] = -94.665810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329395653, states[0] = -94.593081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342539915, states[0] = -94.650785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354312887, states[0] = -94.500613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367402129, states[0] = -94.597590, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Coppini_2000-conf_178.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Coppini_2000-conf_178_0_r2097457768_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Coppini_2000-conf_178_0_r2097457768_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.223741
     * GNaL_b in INaL: 0.005757
     * Gto_b in Ito: 0.084934
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031832
     * GKs_b in IKs: 0.001934
     * GK1_b in IK1: 0.164454
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.444369
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033682
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1367402129
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.597590 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1383843071, states[0] = -94.665331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399537322, states[0] = -94.650185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413362402, states[0] = -94.564405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429535264, states[0] = -94.649728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441295418, states[0] = -94.469202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455130795, states[0] = -28.774760, states[40]= 0.001230
Saving checkpoint... 
Iteration: 1476579774, states[0] = -94.656735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493267524, states[0] = -94.406125, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.537567
 - CaMKt in component CaMK (millimolar): 0.004207
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.486355
 - nass in component intracellular_ions (millimolar): 6.486442
 - ki in component intracellular_ions (millimolar): 145.425742
 - kss in component intracellular_ions (millimolar): 145.425727
 - cansr in component intracellular_ions (millimolar): 1.590195
 - cajsr in component intracellular_ions (millimolar): 1.589504
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003754
 - hf in component INa (dimensionless): 0.873534
 - hs in component INa (dimensionless): 0.873535
 - j in component INa (dimensionless): 0.873541
 - hsp in component INa (dimensionless): 0.713791
 - jp in component INa (dimensionless): 0.873544
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719310
 - hLp in component INaL (dimensionless): 0.511284
 - a in component Ito (dimensionless): 0.000639
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.891944
 - ap in component Ito (dimensionless): 0.000326
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.931740
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975537
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002710
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097579
 - xs1 in component IKs (dimensionless): 0.125172
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997431
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:17:14 (7912): called boinc_finish(0)

</stderr_txt>
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