𝕏

Task 56276305

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_4000-conf_177_1
Workunit 26729596
Created 4 Jul 2024, 22:40:00 UTC
Sent 5 Jul 2024, 17:03:38 UTC
Report deadline 8 Jul 2024, 17:03:38 UTC
Received 6 Jul 2024, 19:42:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231343
Run time 49 min 42 sec
CPU time 41 min 20 sec
Validate state Valid
Credit 44.42
Device peak FLOPS 5.12 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.69 MB
Peak swap size 5.27 MB
Peak disk usage 1.24 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_4000-conf_177.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_4000-conf_177_1_r1830485724_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_4000-conf_177_1_r1830485724_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.660143
     * GNaL_b in INaL: 0.005790
     * Gto_b in Ito: 0.085042
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031715
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.163793
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.607493
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033890
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6729525, states[0] = -86.820156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16597754, states[0] = -86.732329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26550230, states[0] = -86.671231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34696013, states[0] = -86.646126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44683451, states[0] = -86.615264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54601625, states[0] = -86.589487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64712488, states[0] = -86.576725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74581946, states[0] = -86.558871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84530978, states[0] = -86.544038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94957415, states[0] = -86.545316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105007331, states[0] = -86.538698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114978558, states[0] = -86.534811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125056806, states[0] = -86.529884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135266982, states[0] = -86.523361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145002035, states[0] = -86.526127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152381638, states[0] = -86.475161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160300153, states[0] = -86.411505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170470505, states[0] = -86.504262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180652667, states[0] = -86.523130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190446984, states[0] = -86.496688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199249363, states[0] = -86.515935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210003395, states[0] = 29.260063, states[40]= 0.168837
Saving checkpoint... 
Iteration: 220034515, states[0] = 19.846173, states[40]= 0.004556
Saving checkpoint... 
Iteration: 230540744, states[0] = -86.512973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240731759, states[0] = -86.522167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251248027, states[0] = -86.514442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262015919, states[0] = 21.918628, states[40]= 0.013097
Saving checkpoint... 
Iteration: 271915873, states[0] = -86.506599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281946639, states[0] = -86.506309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292405702, states[0] = -86.480140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302231104, states[0] = -86.309327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312228009, states[0] = -86.304495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322714890, states[0] = -86.521335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332731778, states[0] = -86.521461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342629845, states[0] = -86.519013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352650759, states[0] = -86.519845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363143772, states[0] = -86.515709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373333686, states[0] = -86.512451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383277086, states[0] = -86.513344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393842092, states[0] = -86.506756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404154440, states[0] = -45.182052, states[40]= 0.000058
Saving checkpoint... 
Iteration: 414387011, states[0] = -86.471491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424503412, states[0] = -86.506631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434140085, states[0] = -32.857107, states[40]= 0.000359
Saving checkpoint... 
Iteration: 444330597, states[0] = -86.435214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454818896, states[0] = -86.521184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465588283, states[0] = -86.509063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475572102, states[0] = -86.509240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486022661, states[0] = 21.630445, states[40]= 0.006500
Saving checkpoint... 
Iteration: 495611189, states[0] = -86.508809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505794614, states[0] = -86.507091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515907053, states[0] = -86.506238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526172731, states[0] = -62.594964, states[40]= 0.000003
Saving checkpoint... 
Iteration: 536592935, states[0] = -86.516785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546909981, states[0] = -86.519971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557954235, states[0] = -86.505910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568187928, states[0] = -80.760359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578537187, states[0] = -86.511497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588863296, states[0] = -86.520657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599178177, states[0] = -86.514990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608928061, states[0] = -86.519657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619085711, states[0] = -86.516714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629346042, states[0] = -86.512180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639520519, states[0] = -86.509806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649977591, states[0] = -86.505741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660299577, states[0] = -86.405519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670249145, states[0] = -86.337539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680157112, states[0] = -47.563864, states[40]= 0.000039
Saving checkpoint... 
Iteration: 690221482, states[0] = -86.294017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700555163, states[0] = -86.513506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710838779, states[0] = -86.520932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721289990, states[0] = -86.513043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728460504, states[0] = -86.497654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738220213, states[0] = -86.291848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747865119, states[0] = -86.506494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758679583, states[0] = -86.520547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768698827, states[0] = -86.520921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779144869, states[0] = -86.515567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789610999, states[0] = -86.508753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799702547, states[0] = -86.507839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810400903, states[0] = -86.477793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820412186, states[0] = -86.482416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830556678, states[0] = -86.513637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840731303, states[0] = -86.521275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851030310, states[0] = -86.517731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861060610, states[0] = -86.517149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871387782, states[0] = -86.511516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881417656, states[0] = -86.511092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891598546, states[0] = -86.508867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901512397, states[0] = -86.509855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912071275, states[0] = 10.079281, states[40]= 0.004196
Saving checkpoint... 
Iteration: 921984434, states[0] = -86.505646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932038363, states[0] = 19.049656, states[40]= 0.004363
Saving checkpoint... 
Iteration: 942087810, states[0] = 3.919061, states[40]= 0.003969
Saving checkpoint... 
Iteration: 951931398, states[0] = -86.505986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961838836, states[0] = -86.506652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971888359, states[0] = -86.506282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981916137, states[0] = -86.506085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991693540, states[0] = -86.507887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001765421, states[0] = -86.507240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012091514, states[0] = 2.300864, states[40]= 0.003857
Saving checkpoint... 
Iteration: 1022140311, states[0] = -33.046572, states[40]= 0.000350
Saving checkpoint... 
Iteration: 1032251453, states[0] = -86.341071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042520632, states[0] = -86.509199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052755724, states[0] = -86.521333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062712123, states[0] = -86.521053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072785431, states[0] = -86.521283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083301440, states[0] = -86.512790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093552261, states[0] = -86.509346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104041319, states[0] = 18.380526, states[40]= 0.004272
Saving checkpoint... 
Iteration: 1114260008, states[0] = -86.354100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124215652, states[0] = -86.282263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134511268, states[0] = -86.507770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144706438, states[0] = -86.520964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154750448, states[0] = -86.521304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164664314, states[0] = -86.520073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174836385, states[0] = -86.520871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182167666, states[0] = -57.406071, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1191826426, states[0] = -86.506705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201630728, states[0] = -86.508468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211484192, states[0] = -86.510147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220970060, states[0] = -86.518795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230581489, states[0] = -86.515798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240272203, states[0] = -86.371585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250057211, states[0] = 14.321637, states[40]= 0.004202
Saving checkpoint... 
Iteration: 1259765026, states[0] = -86.507194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269740262, states[0] = -86.507407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279160582, states[0] = -86.515183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288490624, states[0] = -86.504158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298103752, states[0] = -4.101777, states[40]= 0.003065
Saving checkpoint... 
Iteration: 1307698881, states[0] = -86.507777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317218399, states[0] = -86.514138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326836677, states[0] = -86.520839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336373555, states[0] = -86.464288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345952496, states[0] = -86.505771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355723473, states[0] = -86.507541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365944124, states[0] = -86.505823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375881168, states[0] = -86.506258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385396303, states[0] = -86.511297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395148498, states[0] = -86.515383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404859562, states[0] = -86.520551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414399395, states[0] = -86.477024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424193446, states[0] = -84.551474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433951952, states[0] = -86.505758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443712068, states[0] = -86.507629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453475749, states[0] = -86.510209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463215746, states[0] = -86.514157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473185689, states[0] = -86.514689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482938195, states[0] = -86.519317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493008237, states[0] = -86.518030, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.381409
 - CaMKt in component CaMK (millimolar): 0.000889
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.036926
 - nass in component intracellular_ions (millimolar): 6.036971
 - ki in component intracellular_ions (millimolar): 145.959288
 - kss in component intracellular_ions (millimolar): 145.959277
 - cansr in component intracellular_ions (millimolar): 1.248564
 - cajsr in component intracellular_ions (millimolar): 1.248710
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008536
 - hf in component INa (dimensionless): 0.643919
 - hs in component INa (dimensionless): 0.643920
 - j in component INa (dimensionless): 0.643923
 - hsp in component INa (dimensionless): 0.395008
 - jp in component INa (dimensionless): 0.643924
 - mL in component INaL (dimensionless): 0.000250
 - hL in component INaL (dimensionless): 0.463213
 - hLp in component INaL (dimensionless): 0.273547
 - a in component Ito (dimensionless): 0.001107
 - iF in component Ito (dimensionless): 0.999421
 - iS in component Ito (dimensionless): 0.985474
 - ap in component Ito (dimensionless): 0.000564
 - iFp in component Ito (dimensionless): 0.999421
 - iSp in component Ito (dimensionless): 0.991594
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997461
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001260
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020504
 - xs1 in component IKs (dimensionless): 0.037590
 - xs2 in component IKs (dimensionless): 0.000228
 - xk1 in component IK1 (dimensionless): 0.997130
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:19:13 (9544): called boinc_finish(0)

</stderr_txt>
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