𝕏

Task 56276252

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_6000-conf_577_0
Workunit 26729570
Created 4 Jul 2024, 22:40:00 UTC
Sent 5 Jul 2024, 17:03:38 UTC
Report deadline 8 Jul 2024, 17:03:38 UTC
Received 6 Jul 2024, 20:46:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231343
Run time 50 min 32 sec
CPU time 42 min 1 sec
Validate state Valid
Credit 44.58
Device peak FLOPS 5.12 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.71 MB
Peak swap size 5.26 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_6000-conf_577.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_6000-conf_577_0_r1780011379_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_6000-conf_577_0_r1780011379_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.680466
     * GNaL_b in INaL: 0.005755
     * Gto_b in Ito: 0.083985
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031783
     * GKs_b in IKs: 0.001922
     * GK1_b in IK1: 0.162935
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.143272
     * GKb_b in IKb: 0.003796
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033463
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7562567, states[0] = -94.204767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17866143, states[0] = -94.161933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28185289, states[0] = -94.180000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 38542117, states[0] = -94.167579, states[40]= 0.000001
Saving checkpoint... 
Iteration: 48271731, states[0] = -50.652659, states[40]= 0.000501
Saving checkpoint... 
Iteration: 58492761, states[0] = -94.197559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 68542548, states[0] = -94.189762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78765979, states[0] = -94.222514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 88886746, states[0] = -94.204544, states[40]= 0.000001
Saving checkpoint... 
Iteration: 99831524, states[0] = -94.231310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 110025116, states[0] = -94.208482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 120158010, states[0] = -5.278479, states[40]= 0.000470
Saving checkpoint... 
Iteration: 130465029, states[0] = -94.221440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 140365808, states[0] = -94.209897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 150464071, states[0] = -94.129358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160674034, states[0] = -94.219624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 170806218, states[0] = -94.209903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180970057, states[0] = -94.238862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 191141307, states[0] = -94.214407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201035773, states[0] = 34.176385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211068264, states[0] = -94.236760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 221047717, states[0] = -94.215788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 231159397, states[0] = -6.525954, states[40]= 0.000486
Saving checkpoint... 
Iteration: 241036515, states[0] = -94.237855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 250773313, states[0] = -94.219557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 260924248, states[0] = -94.210787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 271155891, states[0] = -94.234222, states[40]= 0.000001
Saving checkpoint... 
Iteration: 281307497, states[0] = -94.213458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 291414938, states[0] = -94.063635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301296045, states[0] = -94.229925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311360734, states[0] = -94.212944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 321267585, states[0] = -65.113034, states[40]= 0.000050
Saving checkpoint... 
Iteration: 331043078, states[0] = -94.237353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 340985904, states[0] = -94.216215, states[40]= 0.000001
Saving checkpoint... 
Iteration: 351204205, states[0] = -25.104528, states[40]= 0.005586
Saving checkpoint... 
Iteration: 360936487, states[0] = -94.239834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 371416919, states[0] = -94.212221, states[40]= 0.000001
Saving checkpoint... 
Iteration: 381361811, states[0] = -93.938314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391948682, states[0] = -94.216348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401592080, states[0] = -94.211100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411761524, states[0] = -94.238474, states[40]= 0.000001
Saving checkpoint... 
Iteration: 421676111, states[0] = -94.220331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 431597722, states[0] = -94.210876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 441526920, states[0] = -94.183083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451701080, states[0] = -94.219681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 461354061, states[0] = -94.212033, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471033681, states[0] = 34.239062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481267131, states[0] = -94.229614, states[40]= 0.000001
Saving checkpoint... 
Iteration: 491309260, states[0] = -94.212148, states[40]= 0.000001
Saving checkpoint... 
Iteration: 501039661, states[0] = 33.880294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511209274, states[0] = -94.231129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 521315762, states[0] = -94.211899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528187639, states[0] = -20.360234, states[40]= 0.002736
Saving checkpoint... 
Iteration: 537556784, states[0] = -94.198052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547636643, states[0] = -94.220227, states[40]= 0.000001
Saving checkpoint... 
Iteration: 557346670, states[0] = -94.211437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 567549510, states[0] = -94.194440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577505958, states[0] = -94.222764, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587615455, states[0] = -94.209749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 597723463, states[0] = -94.234835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 607681238, states[0] = -94.218987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 617627618, states[0] = -94.209495, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627552052, states[0] = -94.195253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637518025, states[0] = -94.222088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 647945173, states[0] = -94.208337, states[40]= 0.000001
Saving checkpoint... 
Iteration: 658176741, states[0] = -94.231128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 668228641, states[0] = -94.211587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 678268130, states[0] = -65.666458, states[40]= 0.000045
Saving checkpoint... 
Iteration: 688222974, states[0] = -94.229524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 698149389, states[0] = -94.212088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 708145754, states[0] = -0.403947, states[40]= 0.000275
Saving checkpoint... 
Iteration: 718102766, states[0] = -94.232995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 728080589, states[0] = -94.212569, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738154826, states[0] = -4.328355, states[40]= 0.000422
Saving checkpoint... 
Iteration: 748427925, states[0] = -94.223467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 758216201, states[0] = -94.211084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 767922064, states[0] = -94.207573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 777681799, states[0] = -94.229293, states[40]= 0.000001
Saving checkpoint... 
Iteration: 787458015, states[0] = -94.222468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 797627615, states[0] = -94.208279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 807505063, states[0] = -94.166046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817157262, states[0] = -94.230654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 826991817, states[0] = -94.212892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 837412744, states[0] = -94.056112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847519984, states[0] = -94.220628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857394178, states[0] = -94.209096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867202237, states[0] = -24.508304, states[40]= 0.005426
Saving checkpoint... 
Iteration: 877044052, states[0] = -94.233681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 887186883, states[0] = -94.210469, states[40]= 0.000001
Saving checkpoint... 
Iteration: 896964755, states[0] = -94.206618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 907093060, states[0] = -94.232018, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917066362, states[0] = -94.211445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927113307, states[0] = 11.539040, states[40]= 0.000025
Saving checkpoint... 
Iteration: 937381872, states[0] = -94.223368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 947252563, states[0] = -94.209508, states[40]= 0.000001
Saving checkpoint... 
Iteration: 957170559, states[0] = -12.622944, states[40]= 0.000617
Saving checkpoint... 
Iteration: 964614592, states[0] = -94.217846, states[40]= 0.000001
Saving checkpoint... 
Iteration: 974415057, states[0] = -94.208176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 984086824, states[0] = 21.097522, states[40]= 0.000002
Saving checkpoint... 
Iteration: 993627755, states[0] = -94.218330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1003107753, states[0] = -94.230923, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1012590658, states[0] = -94.218005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1022010701, states[0] = -94.211355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1031438990, states[0] = -94.207646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1041063773, states[0] = 28.773943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050684789, states[0] = -94.227838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1060246618, states[0] = -94.226314, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1069717164, states[0] = -94.215232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1079136198, states[0] = -94.209643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1088661384, states[0] = -94.206179, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1098211771, states[0] = -27.667704, states[40]= 0.005652
Saving checkpoint... 
Iteration: 1107878118, states[0] = -94.235617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1117640408, states[0] = -94.216311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1127075697, states[0] = -94.209929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136772825, states[0] = -94.205467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146925777, states[0] = -94.234754, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1157013671, states[0] = -94.210410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166439536, states[0] = -94.206732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1175796786, states[0] = -94.205132, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1185433538, states[0] = -94.087709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194996693, states[0] = -94.232850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1204588656, states[0] = -94.216751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1214232453, states[0] = -94.207871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1223669425, states[0] = -94.205237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1233207765, states[0] = -26.242133, states[40]= 0.005729
Saving checkpoint... 
Iteration: 1242639021, states[0] = -94.219090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1252150359, states[0] = -94.227936, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1261648305, states[0] = -94.215189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1271460037, states[0] = -94.205904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1281317647, states[0] = -93.762634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288346554, states[0] = -94.221943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1297862858, states[0] = -94.211397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1307502291, states[0] = -94.205429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1317218143, states[0] = -30.303800, states[40]= 0.005014
Saving checkpoint... 
Iteration: 1323976942, states[0] = -94.232480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1333518126, states[0] = -94.217393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1343310475, states[0] = -94.206390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1352912481, states[0] = -94.203645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1362431196, states[0] = -94.083018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372309850, states[0] = -94.222389, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381795998, states[0] = -94.211829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1391580077, states[0] = -94.204478, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1401160585, states[0] = -7.162779, states[40]= 0.000500
Saving checkpoint... 
Iteration: 1410826432, states[0] = -94.233521, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1420315280, states[0] = -94.221914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429910645, states[0] = -94.209847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1436692934, states[0] = -94.203710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1446380036, states[0] = -93.981684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456031235, states[0] = -94.230149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1463345420, states[0] = -94.205331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1473911936, states[0] = -94.232775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483817331, states[0] = -94.210812, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494144664, states[0] = 0.037336, states[40]= 0.000258
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.078464
 - CaMKt in component CaMK (millimolar): 0.001350
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 7.724798
 - nass in component intracellular_ions (millimolar): 7.724946
 - ki in component intracellular_ions (millimolar): 144.114168
 - kss in component intracellular_ions (millimolar): 144.114155
 - cansr in component intracellular_ions (millimolar): 1.760510
 - cajsr in component intracellular_ions (millimolar): 1.761727
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003932
 - hf in component INa (dimensionless): 0.864962
 - hs in component INa (dimensionless): 0.864962
 - j in component INa (dimensionless): 0.864962
 - hsp in component INa (dimensionless): 0.698128
 - jp in component INa (dimensionless): 0.864963
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706913
 - hLp in component INaL (dimensionless): 0.513104
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999132
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999679
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999268
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004197
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000651
 - xs1 in component IKs (dimensionless): 0.019806
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997545
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
05:45:43 (26016): called boinc_finish(0)

</stderr_txt>
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