𝕏

Task 56275292

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pueyo_APDR-conf_276_0
Workunit 26729090
Created 4 Jul 2024, 22:39:29 UTC
Sent 5 Jul 2024, 16:58:41 UTC
Report deadline 9 Jul 2024, 2:34:41 UTC
Received 6 Jul 2024, 10:22:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227166
Run time 2 hours 19 min 31 sec
CPU time 2 hours 17 min 29 sec
Validate state Valid
Credit 61.76
Device peak FLOPS 5.21 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pueyo_APDR-conf_276.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pueyo_APDR-conf_276_0_r971720369_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pueyo_APDR-conf_276_0_r971720369_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.764109
     * GNaL_b in INaL: 0.005862
     * Gto_b in Ito: 0.084041
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031736
     * GKs_b in IKs: 0.001937
     * GK1_b in IK1: 0.163267
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.219173
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033410
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15462948, states[0] = -95.106200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30842020, states[0] = -95.037888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46046159, states[0] = 12.769441, states[40]= 0.005051
Saving checkpoint... 
Iteration: 61527445, states[0] = 19.337282, states[40]= 0.006473
Saving checkpoint... 
Iteration: 76952025, states[0] = -95.038986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92535885, states[0] = 16.816001, states[40]= 0.005478
Saving checkpoint... 
Iteration: 107913623, states[0] = -95.024117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123453591, states[0] = -95.031237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138851162, states[0] = -94.999391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154214825, states[0] = -94.862728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169491192, states[0] = -95.034892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184937268, states[0] = -95.025761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200359442, states[0] = -95.001645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215773804, states[0] = -94.943356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231258103, states[0] = -94.926036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246769519, states[0] = -94.938792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262219801, states[0] = -94.870399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277655507, states[0] = -81.042072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293086967, states[0] = -7.421902, states[40]= 0.002877
Saving checkpoint... 
Iteration: 308643833, states[0] = -63.827807, states[40]= 0.000003
Saving checkpoint... 
Iteration: 324121435, states[0] = -39.513632, states[40]= 0.000140
Saving checkpoint... 
Iteration: 339685626, states[0] = -94.800267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355147146, states[0] = -68.052640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 370617506, states[0] = -35.677172, states[40]= 0.000239
Saving checkpoint... 
Iteration: 386136135, states[0] = -54.962655, states[40]= 0.000012
Saving checkpoint... 
Iteration: 401478621, states[0] = -95.032357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416927688, states[0] = -95.023068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432446104, states[0] = -95.026931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447958434, states[0] = -95.029166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463346086, states[0] = -94.995006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478839269, states[0] = -94.991520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494291514, states[0] = -94.959394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509803951, states[0] = -94.969266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525284067, states[0] = -94.952836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540766387, states[0] = -94.935163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555974210, states[0] = -95.031617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571345559, states[0] = -94.994676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586840196, states[0] = -94.991937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602206509, states[0] = -94.845727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617686329, states[0] = -94.802141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633089780, states[0] = -9.746361, states[40]= 0.002383
Saving checkpoint... 
Iteration: 648436823, states[0] = -95.024923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663915382, states[0] = -95.019926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679067017, states[0] = 4.578128, states[40]= 0.004687
Saving checkpoint... 
Iteration: 694483148, states[0] = -95.032799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709941851, states[0] = -95.025917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725460627, states[0] = -95.029362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740623955, states[0] = -42.033520, states[40]= 0.000096
Saving checkpoint... 
Iteration: 755877452, states[0] = -95.008189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771057272, states[0] = 8.834122, states[40]= 0.004881
Saving checkpoint... 
Iteration: 786454222, states[0] = -95.028212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801945351, states[0] = -95.026549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817339638, states[0] = -94.991497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832991000, states[0] = -95.033741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848386563, states[0] = -95.011324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863746224, states[0] = -94.910495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878940029, states[0] = -95.025440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894524493, states[0] = 20.305505, states[40]= 0.007250
Saving checkpoint... 
Iteration: 909750197, states[0] = -94.915692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925269835, states[0] = -94.938616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940651792, states[0] = -74.801535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955912294, states[0] = -95.018936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971237730, states[0] = -94.898522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986643796, states[0] = -63.780764, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1001868592, states[0] = -95.004650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017337662, states[0] = -94.990322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032558559, states[0] = 8.300955, states[40]= 0.004864
Saving checkpoint... 
Iteration: 1047787028, states[0] = -94.955160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063049792, states[0] = 11.813339, states[40]= 0.004978
Saving checkpoint... 
Iteration: 1078292975, states[0] = -94.960246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093690866, states[0] = -94.813157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109139362, states[0] = -58.574469, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1124843012, states[0] = -94.993044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140422660, states[0] = -95.021427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155953684, states[0] = -95.027879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171280859, states[0] = -94.949448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186662171, states[0] = -90.944609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201938120, states[0] = -95.024841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217286309, states[0] = -94.954413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232769021, states[0] = -94.937557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248380031, states[0] = -95.008806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263849140, states[0] = -94.995979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279512240, states[0] = 22.675196, states[40]= 0.031672
Saving checkpoint... 
Iteration: 1295031497, states[0] = 18.333991, states[40]= 0.005880
Saving checkpoint... 
Iteration: 1310405034, states[0] = -95.016726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325846311, states[0] = -94.994565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341500809, states[0] = 45.033218, states[40]= 0.013945
Saving checkpoint... 
Iteration: 1357020291, states[0] = 21.257598, states[40]= 0.009435
Saving checkpoint... 
Iteration: 1372565576, states[0] = 5.244686, states[40]= 0.004728
Saving checkpoint... 
Iteration: 1388140056, states[0] = -59.366415, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1403549733, states[0] = 11.836221, states[40]= 0.004979
Saving checkpoint... 
Iteration: 1418988071, states[0] = -95.032991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434398571, states[0] = -95.014764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449718304, states[0] = -94.866973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465391239, states[0] = -95.012466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480722082, states[0] = -94.873483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496263112, states[0] = -94.930912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511874055, states[0] = -95.098749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527360927, states[0] = 1.886663, states[40]= 0.005020
Saving checkpoint... 
Iteration: 1542881679, states[0] = -95.282064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1558185632, states[0] = -95.292380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573549901, states[0] = 7.751788, states[40]= 0.005587
Saving checkpoint... 
Iteration: 1589033469, states[0] = -95.248151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604671641, states[0] = -95.290342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620126697, states[0] = -71.098444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1635805960, states[0] = -95.209699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651186546, states[0] = -95.304099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666737736, states[0] = -95.257507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1682222108, states[0] = -64.503841, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1697613824, states[0] = -95.223763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1713160511, states[0] = -95.104422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1728605219, states[0] = 29.142164, states[40]= 0.127395
Saving checkpoint... 
Iteration: 1743990608, states[0] = -27.384347, states[40]= 0.000587
Saving checkpoint... 
Iteration: 1759531087, states[0] = 16.763702, states[40]= 0.006909
Saving checkpoint... 
Iteration: 1774949915, states[0] = -94.956433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790538238, states[0] = -90.630134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805835273, states[0] = -95.041192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821358575, states[0] = -95.036753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836620681, states[0] = -40.326993, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1851976019, states[0] = -95.046204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867440331, states[0] = -95.034433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883016437, states[0] = 21.918187, states[40]= 0.014633
Saving checkpoint... 
Iteration: 1898713736, states[0] = -94.862359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914425136, states[0] = -95.023872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930109050, states[0] = -27.717007, states[40]= 0.000580
Saving checkpoint... 
Iteration: 1945476254, states[0] = -95.031941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961001524, states[0] = 47.920190, states[40]= 0.062550
Saving checkpoint... 
Iteration: 1976326621, states[0] = -94.983807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991826501, states[0] = -94.983581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007563605, states[0] = 6.129111, states[40]= 0.004775
Saving checkpoint... 
Iteration: 2023383492, states[0] = -95.009569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038930986, states[0] = -95.022780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054541105, states[0] = 15.073191, states[40]= 0.005197
Saving checkpoint... 
Iteration: 2070112761, states[0] = -31.140200, states[40]= 0.000417
Saving checkpoint... 
Iteration: 2085777272, states[0] = -94.945380, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909851
 - CaMKt in component CaMK (millimolar): 0.006988
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.578129
 - nass in component intracellular_ions (millimolar): 6.578188
 - ki in component intracellular_ions (millimolar): 145.399379
 - kss in component intracellular_ions (millimolar): 145.399360
 - cansr in component intracellular_ions (millimolar): 1.312173
 - cajsr in component intracellular_ions (millimolar): 1.274138
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880139
 - hs in component INa (dimensionless): 0.880135
 - j in component INa (dimensionless): 0.880106
 - hsp in component INa (dimensionless): 0.726092
 - jp in component INa (dimensionless): 0.880087
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710007
 - hLp in component INaL (dimensionless): 0.451875
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620771
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695537
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934869
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001603
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331474
 - xs1 in component IKs (dimensionless): 0.242349
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:44:06 (70796): called boinc_finish(0)

</stderr_txt>
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