𝕏

Task 56275252

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_4000-conf_276_0
Workunit 26729070
Created 4 Jul 2024, 22:39:28 UTC
Sent 5 Jul 2024, 17:02:13 UTC
Report deadline 8 Jul 2024, 17:02:13 UTC
Received 6 Jul 2024, 1:27:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222530
Run time 2 hours 34 min 50 sec
CPU time 2 hours 34 min 44 sec
Validate state Valid
Credit 42.87
Device peak FLOPS 3.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 3.23 MB
Peak swap size 4.31 MB
Peak disk usage 1.25 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_4000-conf_276.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_4000-conf_276_0_r351699126_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_4000-conf_276_0_r351699126_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.764109
     * GNaL_b in INaL: 0.005862
     * Gto_b in Ito: 0.084041
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031736
     * GKs_b in IKs: 0.001937
     * GK1_b in IK1: 0.163267
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.219173
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033410
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9362927, states[0] = -86.779575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18848534, states[0] = -86.713549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28328089, states[0] = -86.576228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37907697, states[0] = -86.614612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47834306, states[0] = -86.587240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57843224, states[0] = -86.566458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68363154, states[0] = -86.500441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78263143, states[0] = -86.389606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87663139, states[0] = -86.531965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97595482, states[0] = -86.525770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107284386, states[0] = -86.524706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116964471, states[0] = -86.526433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126313097, states[0] = -86.423390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136081877, states[0] = 6.108478, states[40]= 0.004098
Saving checkpoint... 
Iteration: 145707491, states[0] = -86.507634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155369353, states[0] = -86.510062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165331094, states[0] = -86.509352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175115536, states[0] = -86.512109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184569597, states[0] = -86.510139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194242621, states[0] = -86.321236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203879743, states[0] = -86.500425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213522563, states[0] = -86.503430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223141695, states[0] = -86.509037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232967606, states[0] = -86.512113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242431431, states[0] = -86.482264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252107802, states[0] = -6.831186, states[40]= 0.002580
Saving checkpoint... 
Iteration: 261580451, states[0] = -86.501712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271151836, states[0] = -86.508021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281196373, states[0] = -86.507120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290985274, states[0] = -86.511065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300865879, states[0] = -86.513028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311123804, states[0] = -86.508306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321210235, states[0] = -86.506679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331089880, states[0] = -86.508896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341184682, states[0] = -86.507091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351016546, states[0] = -86.510276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361088168, states[0] = -86.508876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370806591, states[0] = -86.513506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380137652, states[0] = -30.940535, states[40]= 0.000453
Saving checkpoint... 
Iteration: 390450244, states[0] = -86.487188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400508171, states[0] = -86.499614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409618643, states[0] = -86.500797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419318594, states[0] = -86.504729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429112964, states[0] = -86.508351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438551683, states[0] = -86.505393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448512143, states[0] = -86.500227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458368706, states[0] = -86.453747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467997274, states[0] = -86.497668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477350469, states[0] = -86.504214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487013653, states[0] = -86.510251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496959600, states[0] = -86.511267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506377369, states[0] = -86.458578, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_4000-conf_276.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_4000-conf_276_0_r351699126_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_4000-conf_276_0_r351699126_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.764109
     * GNaL_b in INaL: 0.005862
     * Gto_b in Ito: 0.084041
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031736
     * GKs_b in IKs: 0.001937
     * GK1_b in IK1: 0.163267
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.219173
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033410
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 506377369
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.458578 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 516382201, states[0] = -86.461114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526077562, states[0] = 7.900296, states[40]= 0.004154
Saving checkpoint... 
Iteration: 536350220, states[0] = -86.442000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546347997, states[0] = -86.440447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555772651, states[0] = -86.499289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565942875, states[0] = -86.497998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575474035, states[0] = -86.502451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585518880, states[0] = -86.501885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595500986, states[0] = -86.502104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605004241, states[0] = -86.510407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614799888, states[0] = -86.513472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624817927, states[0] = -86.513330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634633249, states[0] = -86.511246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644162627, states[0] = -52.751397, states[40]= 0.000016
Saving checkpoint... 
Iteration: 654193719, states[0] = -84.688661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664225919, states[0] = -86.292591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674347540, states[0] = -86.440100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684169399, states[0] = -59.291024, states[40]= 0.000005
Saving checkpoint... 
Iteration: 694282549, states[0] = -86.377164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703955564, states[0] = -86.497887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713502746, states[0] = -86.502060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723206124, states[0] = -86.506559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733028604, states[0] = -86.509913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742892953, states[0] = -86.512359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752488504, states[0] = -86.496025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762132559, states[0] = -26.689315, states[40]= 0.000673
Saving checkpoint... 
Iteration: 772079323, states[0] = 7.254767, states[40]= 0.004133
Saving checkpoint... 
Iteration: 781956284, states[0] = -86.497867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791644872, states[0] = -86.500437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800911710, states[0] = -86.512047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810498970, states[0] = -86.497958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819817528, states[0] = -86.498868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829182189, states[0] = -86.506971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838495628, states[0] = -86.497352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848157050, states[0] = -47.651520, states[40]= 0.000039
Saving checkpoint... 
Iteration: 858071641, states[0] = 9.956637, states[40]= 0.004203
Saving checkpoint... 
Iteration: 867909171, states[0] = -86.498171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878189367, states[0] = -82.157285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888304783, states[0] = -86.402921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898043460, states[0] = 17.925262, states[40]= 0.004236
Saving checkpoint... 
Iteration: 908037893, states[0] = 19.214693, states[40]= 0.004387
Saving checkpoint... 
Iteration: 917746004, states[0] = -86.499451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927630977, states[0] = -86.500555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937686147, states[0] = -86.500000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947435071, states[0] = -86.502899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957206814, states[0] = -86.506502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967088150, states[0] = -86.508716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977049724, states[0] = -86.509458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987022083, states[0] = -86.509991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997052485, states[0] = -86.509401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007084359, states[0] = -86.508782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016818512, states[0] = -86.513250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026823774, states[0] = -86.513199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036773584, states[0] = -86.513510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046661324, states[0] = -86.512207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056357012, states[0] = -86.446444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066223881, states[0] = -86.289326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076037806, states[0] = 19.233832, states[40]= 0.004390
Saving checkpoint... 
Iteration: 1086001802, states[0] = 38.522401, states[40]= 0.109236
Saving checkpoint... 
Iteration: 1095919267, states[0] = -86.498057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106070482, states[0] = 10.339797, states[40]= 0.004209
Saving checkpoint... 
Iteration: 1116157396, states[0] = -47.962834, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1125790615, states[0] = -86.499029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135628660, states[0] = -86.500539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145491730, states[0] = -86.502116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155246200, states[0] = -86.505774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164825975, states[0] = -86.513151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174627300, states[0] = -86.510871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184423008, states[0] = -86.478477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194340163, states[0] = -86.434596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204357580, states[0] = -86.446783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214179700, states[0] = -70.914588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224446082, states[0] = -86.485835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234421282, states[0] = -86.477852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244095273, states[0] = 0.490001, states[40]= 0.003701
Saving checkpoint... 
Iteration: 1253718982, states[0] = -86.499631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263716442, states[0] = -86.499652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273669114, states[0] = -86.500102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283143747, states[0] = -86.507596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293014555, states[0] = -86.510078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303027376, states[0] = -86.509829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312863555, states[0] = -86.512680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322746983, states[0] = -86.513450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332434669, states[0] = -86.482364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342527460, states[0] = -86.502285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352570367, states[0] = -86.507041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362265368, states[0] = -86.353632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372097329, states[0] = -0.546583, states[40]= 0.003585
Saving checkpoint... 
Iteration: 1381982115, states[0] = -86.497585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391470489, states[0] = -86.502342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401193173, states[0] = -86.506663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410666985, states[0] = -86.512303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420250970, states[0] = -86.331890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429900399, states[0] = -86.498126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440242737, states[0] = -86.318887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450517204, states[0] = -86.500805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460527424, states[0] = -86.502258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470346880, states[0] = -86.439479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480396024, states[0] = -86.467598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490115013, states[0] = -12.214114, states[40]= 0.001630
Saving checkpoint... 
Iteration: 1499924941, states[0] = -86.497941, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.373420
 - CaMKt in component CaMK (millimolar): 0.000890
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.047430
 - nass in component intracellular_ions (millimolar): 6.047475
 - ki in component intracellular_ions (millimolar): 145.948616
 - kss in component intracellular_ions (millimolar): 145.948606
 - cansr in component intracellular_ions (millimolar): 1.249332
 - cajsr in component intracellular_ions (millimolar): 1.249476
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008543
 - hf in component INa (dimensionless): 0.643618
 - hs in component INa (dimensionless): 0.643619
 - j in component INa (dimensionless): 0.643622
 - hsp in component INa (dimensionless): 0.394695
 - jp in component INa (dimensionless): 0.643623
 - mL in component INaL (dimensionless): 0.000251
 - hL in component INaL (dimensionless): 0.462948
 - hLp in component INaL (dimensionless): 0.273336
 - a in component Ito (dimensionless): 0.001108
 - iF in component Ito (dimensionless): 0.999420
 - iS in component Ito (dimensionless): 0.985471
 - ap in component Ito (dimensionless): 0.000565
 - iFp in component Ito (dimensionless): 0.999420
 - iSp in component Ito (dimensionless): 0.991589
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997456
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001263
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020564
 - xs1 in component IKs (dimensionless): 0.037570
 - xs2 in component IKs (dimensionless): 0.000228
 - xk1 in component IK1 (dimensionless): 0.997132
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:43:04 (3395237): called boinc_finish(0)

</stderr_txt>
]]>


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