𝕏

Task 56273279

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_333-conf_474_0
Workunit 26728085
Created 4 Jul 2024, 22:38:21 UTC
Sent 5 Jul 2024, 16:56:38 UTC
Report deadline 8 Jul 2024, 16:56:38 UTC
Received 7 Jul 2024, 13:15:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231073
Run time 55 min 39 sec
CPU time 48 min 23 sec
Validate state Valid
Credit 45.70
Device peak FLOPS 5.32 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.74 MB
Peak swap size 32.57 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_333-conf_474.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_333-conf_474_0_r118612586_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_333-conf_474_0_r118612586_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.275108
     * GNaL_b in INaL: 0.005914
     * Gto_b in Ito: 0.084328
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031890
     * GKs_b in IKs: 0.001927
     * GK1_b in IK1: 0.164445
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.335358
     * GKb_b in IKb: 0.003796
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032119
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12422089, states[0] = -30.521843, states[40]= 0.000850
Saving checkpoint... 
Iteration: 29436015, states[0] = -51.241167, states[40]= 0.000111
Saving checkpoint... 
Iteration: 42704689, states[0] = 18.083599, states[40]= 0.000010
Saving checkpoint... 
Iteration: 59208542, states[0] = 14.347124, states[40]= 0.000021
Saving checkpoint... 
Iteration: 76011021, states[0] = 29.120637, states[40]= 0.002793
Saving checkpoint... 
Iteration: 92900344, states[0] = -14.209804, states[40]= 0.000308
Saving checkpoint... 
Iteration: 110517742, states[0] = 25.208203, states[40]= 0.000072
Saving checkpoint... 
Iteration: 125565035, states[0] = -16.323870, states[40]= 0.000279
Saving checkpoint... 
Iteration: 143657859, states[0] = 28.346335, states[40]= 0.341428
Saving checkpoint... 
Iteration: 161219410, states[0] = -4.263193, states[40]= 0.000305
Saving checkpoint... 
Iteration: 177244925, states[0] = -41.889371, states[40]= 0.000176
Saving checkpoint... 
Iteration: 193399020, states[0] = -27.065656, states[40]= 0.000276
Saving checkpoint... 
Iteration: 210393762, states[0] = -22.040142, states[40]= 0.000257
Saving checkpoint... 
Iteration: 229621450, states[0] = -84.782185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 247247566, states[0] = -54.720200, states[40]= 0.000056
Saving checkpoint... 
Iteration: 264969634, states[0] = -85.013664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 284271140, states[0] = -84.251718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302286198, states[0] = -84.859291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 316685601, states[0] = 12.100720, states[40]= 0.000028
Saving checkpoint... 
Iteration: 332182279, states[0] = 13.333832, states[40]= 0.000021
Saving checkpoint... 
Iteration: 346796085, states[0] = -85.022176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 363806057, states[0] = 28.650505, states[40]= 0.093937
Saving checkpoint... 
Iteration: 379349204, states[0] = 9.775023, states[40]= 0.000047
Saving checkpoint... 
Iteration: 395381899, states[0] = -31.309618, states[40]= 0.000277
Saving checkpoint... 
Iteration: 413065348, states[0] = -56.108900, states[40]= 0.000049
Saving checkpoint... 
Iteration: 432432107, states[0] = -84.722632, states[40]= 0.000001
Saving checkpoint... 
Iteration: 451547773, states[0] = -37.821411, states[40]= 0.000224
Saving checkpoint... 
Iteration: 463192901, states[0] = -9.106270, states[40]= 0.000327
Saving checkpoint... 
Iteration: 480557840, states[0] = -55.068136, states[40]= 0.000054
Saving checkpoint... 
Iteration: 496732448, states[0] = -68.893354, states[40]= 0.000011
Saving checkpoint... 
Iteration: 512864067, states[0] = -22.812835, states[40]= 0.000259
Saving checkpoint... 
Iteration: 526604973, states[0] = -84.942041, states[40]= 0.000001
Saving checkpoint... 
Iteration: 543711555, states[0] = -46.213135, states[40]= 0.000125
Saving checkpoint... 
Iteration: 558893893, states[0] = -70.416245, states[40]= 0.000009
Saving checkpoint... 
Iteration: 577077329, states[0] = -84.434525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 595353590, states[0] = -19.607853, states[40]= 0.000258
Saving checkpoint... 
Iteration: 614599139, states[0] = -84.969431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 632742193, states[0] = -84.621659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 645453103, states[0] = 29.229443, states[40]= 0.003952
Saving checkpoint... 
Iteration: 661004741, states[0] = -6.767509, states[40]= 0.000323
Saving checkpoint... 
Iteration: 676171448, states[0] = -8.882413, states[40]= 0.000328
Saving checkpoint... 
Iteration: 692640438, states[0] = 17.146558, states[40]= 0.000007
Saving checkpoint... 
Iteration: 711264132, states[0] = 34.938924, states[40]= 1.171874
Saving checkpoint... 
Iteration: 725372979, states[0] = -63.910755, states[40]= 0.000020
Saving checkpoint... 
Iteration: 740727218, states[0] = -84.390190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 755318939, states[0] = 3.799956, states[40]= 0.000140
Saving checkpoint... 
Iteration: 773994261, states[0] = -7.859163, states[40]= 0.000328
Saving checkpoint... 
Iteration: 785364391, states[0] = -60.158860, states[40]= 0.000031
Saving checkpoint... 
Iteration: 802474652, states[0] = 8.956197, states[40]= 0.000056
Saving checkpoint... 
Iteration: 820140812, states[0] = 7.977983, states[40]= 0.000069
Saving checkpoint... 
Iteration: 837012142, states[0] = -41.669497, states[40]= 0.000177
Saving checkpoint... 
Iteration: 854592392, states[0] = 29.182066, states[40]= 0.043207
Saving checkpoint... 
Iteration: 868038436, states[0] = -81.466545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 884854463, states[0] = -60.177669, states[40]= 0.000031
Saving checkpoint... 
Iteration: 900682908, states[0] = -55.590983, states[40]= 0.000051
Saving checkpoint... 
Iteration: 918375336, states[0] = -84.306743, states[40]= 0.000001
Saving checkpoint... 
Iteration: 935279402, states[0] = 19.261802, states[40]= 0.000005
Saving checkpoint... 
Iteration: 951193159, states[0] = -77.837853, states[40]= 0.000003
Saving checkpoint... 
Iteration: 968133208, states[0] = 1.740106, states[40]= 0.000184
Saving checkpoint... 
Iteration: 985431912, states[0] = 24.360869, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1001849346, states[0] = -69.965431, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1018994958, states[0] = -42.998095, states[40]= 0.000161
Saving checkpoint... 
Iteration: 1036091185, states[0] = 25.514056, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1053260877, states[0] = 23.096741, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1071757977, states[0] = 23.655043, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1090651253, states[0] = -38.752778, states[40]= 0.000214
Saving checkpoint... 
Iteration: 1108276148, states[0] = 9.914746, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1125478744, states[0] = -35.580737, states[40]= 0.000247
Saving checkpoint... 
Iteration: 1139810480, states[0] = -35.367877, states[40]= 0.000250
Saving checkpoint... 
Iteration: 1154230511, states[0] = 29.417406, states[40]= 0.025449
Saving checkpoint... 
Iteration: 1171842927, states[0] = -82.413538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190279371, states[0] = 0.036137, states[40]= 0.000221
Saving checkpoint... 
Iteration: 1206850528, states[0] = -84.549461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1223420228, states[0] = 17.447136, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1238757680, states[0] = 13.771632, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1256660455, states[0] = -74.857856, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1259320607, states[0] = -65.371419, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1275667037, states[0] = -82.958877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1292932483, states[0] = 3.238445, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1309054380, states[0] = 29.049543, states[40]= 0.002761
Saving checkpoint... 
Iteration: 1327061473, states[0] = 25.811884, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1344306641, states[0] = -57.512614, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1360755843, states[0] = 6.026273, states[40]= 0.000098
Saving checkpoint... 
Iteration: 1376702037, states[0] = 28.141658, states[40]= 0.253624
Saving checkpoint... 
Iteration: 1390305710, states[0] = -62.693542, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1407679802, states[0] = -84.843612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1424294528, states[0] = -51.926125, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1441703905, states[0] = 29.531361, states[40]= 0.011476
Saving checkpoint... 
Iteration: 1458707408, states[0] = 28.723567, states[40]= 0.001702
Saving checkpoint... 
Iteration: 1475453301, states[0] = -48.232861, states[40]= 0.000105
Saving checkpoint... 
Iteration: 1491816527, states[0] = -84.087741, states[40]= 0.000001
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.851999
 - CaMKt in component CaMK (millimolar): 0.217414
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.284660
 - nass in component intracellular_ions (millimolar): 7.285014
 - ki in component intracellular_ions (millimolar): 143.831083
 - kss in component intracellular_ions (millimolar): 143.831047
 - cansr in component intracellular_ions (millimolar): 3.339968
 - cajsr in component intracellular_ions (millimolar): 1.926490
 - cai in component intracellular_ions (millimolar): 0.000162
 - m in component INa (dimensionless): 0.009952
 - hf in component INa (dimensionless): 0.584453
 - hs in component INa (dimensionless): 0.583405
 - j in component INa (dimensionless): 0.553878
 - hsp in component INa (dimensionless): 0.331905
 - jp in component INa (dimensionless): 0.512171
 - mL in component INaL (dimensionless): 0.000334
 - hL in component INaL (dimensionless): 0.183267
 - hLp in component INaL (dimensionless): 0.074775
 - a in component Ito (dimensionless): 0.001228
 - iF in component Ito (dimensionless): 0.999238
 - iS in component Ito (dimensionless): 0.131153
 - ap in component Ito (dimensionless): 0.000626
 - iFp in component Ito (dimensionless): 0.999238
 - iSp in component Ito (dimensionless): 0.146647
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.677094
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.928677
 - jca in component ICaL (dimensionless): 0.911255
 - ffp in component ICaL (dimensionless): 0.998926
 - fcafp in component ICaL (dimensionless): 0.999939
 - nca in component ICaL (dimensionless): 0.042151
 - xrf in component IKr (dimensionless): 0.100818
 - xrs in component IKr (dimensionless): 0.872723
 - xs1 in component IKs (dimensionless): 0.570892
 - xs2 in component IKs (dimensionless): 0.007197
 - xk1 in component IK1 (dimensionless): 0.996735
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
08:14:55 (84269): called boinc_finish(0)

</stderr_txt>
]]>


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