𝕏

Task 56273277

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_333-conf_374_0
Workunit 26728084
Created 4 Jul 2024, 22:38:21 UTC
Sent 5 Jul 2024, 16:56:38 UTC
Report deadline 8 Jul 2024, 16:56:38 UTC
Received 6 Jul 2024, 19:30:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231073
Run time 57 min 53 sec
CPU time 48 min 38 sec
Validate state Valid
Credit 45.35
Device peak FLOPS 5.32 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.74 MB
Peak swap size 32.57 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_333-conf_374.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_333-conf_374_0_r1087302513_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_333-conf_374_0_r1087302513_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.408194
     * GNaL_b in INaL: 0.005918
     * Gto_b in Ito: 0.084070
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031719
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.163498
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.535293
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033920
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9818897, states[0] = -84.966891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25424806, states[0] = -35.678802, states[40]= 0.000428
Saving checkpoint... 
Iteration: 43542527, states[0] = 15.163834, states[40]= 0.000022
Saving checkpoint... 
Iteration: 61746678, states[0] = -27.494291, states[40]= 0.000332
Saving checkpoint... 
Iteration: 77754259, states[0] = -40.308617, states[40]= 0.000215
Saving checkpoint... 
Iteration: 94399601, states[0] = -13.253823, states[40]= 0.000328
Saving checkpoint... 
Iteration: 110043468, states[0] = 9.338733, states[40]= 0.000057
Saving checkpoint... 
Iteration: 126130444, states[0] = -84.757324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141555234, states[0] = -4.816499, states[40]= 0.000325
Saving checkpoint... 
Iteration: 154869557, states[0] = 11.327522, states[40]= 0.000036
Saving checkpoint... 
Iteration: 171860562, states[0] = 16.267153, states[40]= 0.000010
Saving checkpoint... 
Iteration: 189192407, states[0] = 16.108372, states[40]= 0.000010
Saving checkpoint... 
Iteration: 207273001, states[0] = -82.528517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 224968718, states[0] = -84.963012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 241410666, states[0] = -48.957785, states[40]= 0.000101
Saving checkpoint... 
Iteration: 258976058, states[0] = 34.965531, states[40]= 1.160460
Saving checkpoint... 
Iteration: 274852234, states[0] = 14.987070, states[40]= 0.000014
Saving checkpoint... 
Iteration: 291989844, states[0] = 28.936250, states[40]= 0.002386
Saving checkpoint... 
Iteration: 309692783, states[0] = 7.245146, states[40]= 0.000083
Saving checkpoint... 
Iteration: 322614670, states[0] = -84.816464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 337152658, states[0] = 28.767158, states[40]= 0.001875
Saving checkpoint... 
Iteration: 350611195, states[0] = -84.803999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 365103623, states[0] = -84.675307, states[40]= 0.000001
Saving checkpoint... 
Iteration: 380686865, states[0] = 6.287346, states[40]= 0.000098
Saving checkpoint... 
Iteration: 393614774, states[0] = -84.908900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411438994, states[0] = -84.808776, states[40]= 0.000001
Saving checkpoint... 
Iteration: 427784511, states[0] = -84.980841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444812977, states[0] = 27.271894, states[40]= 0.000380
Saving checkpoint... 
Iteration: 460223346, states[0] = -50.566490, states[40]= 0.000087
Saving checkpoint... 
Iteration: 475143886, states[0] = 27.023742, states[40]= 0.000305
Saving checkpoint... 
Iteration: 492699597, states[0] = -22.936570, states[40]= 0.000268
Saving checkpoint... 
Iteration: 508892306, states[0] = -60.300871, states[40]= 0.000032
Saving checkpoint... 
Iteration: 524805601, states[0] = 27.019145, states[40]= 0.000303
Saving checkpoint... 
Iteration: 540340766, states[0] = 3.527293, states[40]= 0.000152
Saving checkpoint... 
Iteration: 553956267, states[0] = 29.282975, states[40]= 0.036193
Saving checkpoint... 
Iteration: 569416619, states[0] = -84.664855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 584418588, states[0] = -84.744800, states[40]= 0.000001
Saving checkpoint... 
Iteration: 599865167, states[0] = -36.161016, states[40]= 0.000249
Saving checkpoint... 
Iteration: 614756853, states[0] = -84.864309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 629959114, states[0] = 28.030652, states[40]= 0.000784
Saving checkpoint... 
Iteration: 645296997, states[0] = 25.470704, states[40]= 0.000089
Saving checkpoint... 
Iteration: 659351277, states[0] = -25.295007, states[40]= 0.000276
Saving checkpoint... 
Iteration: 675832265, states[0] = -1.477502, states[40]= 0.000266
Saving checkpoint... 
Iteration: 692208297, states[0] = -61.691522, states[40]= 0.000027
Saving checkpoint... 
Iteration: 708597002, states[0] = 34.404718, states[40]= 0.903180
Saving checkpoint... 
Iteration: 722837269, states[0] = -14.255724, states[40]= 0.000302
Saving checkpoint... 
Iteration: 739354152, states[0] = -40.057441, states[40]= 0.000203
Saving checkpoint... 
Iteration: 754872658, states[0] = -67.543766, states[40]= 0.000013
Saving checkpoint... 
Iteration: 765761349, states[0] = 29.152974, states[40]= 0.477190
Saving checkpoint... 
Iteration: 783106025, states[0] = 29.231477, states[40]= 0.003932
Saving checkpoint... 
Iteration: 799004148, states[0] = -25.523820, states[40]= 0.000278
Saving checkpoint... 
Iteration: 815843330, states[0] = -35.828146, states[40]= 0.000253
Saving checkpoint... 
Iteration: 831227801, states[0] = -84.739943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 846182146, states[0] = -47.094835, states[40]= 0.000119
Saving checkpoint... 
Iteration: 863772445, states[0] = 26.710986, states[40]= 0.000232
Saving checkpoint... 
Iteration: 879291442, states[0] = 15.224936, states[40]= 0.000013
Saving checkpoint... 
Iteration: 895751512, states[0] = 28.327025, states[40]= 0.153578
Saving checkpoint... 
Iteration: 911709193, states[0] = -84.264600, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927548592, states[0] = -84.672102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944960316, states[0] = 9.041601, states[40]= 0.000058
Saving checkpoint... 
Iteration: 962488036, states[0] = -25.843882, states[40]= 0.000279
Saving checkpoint... 
Iteration: 980134368, states[0] = -0.601106, states[40]= 0.000245
Saving checkpoint... 
Iteration: 995249687, states[0] = 29.472220, states[40]= 0.007576
Saving checkpoint... 
Iteration: 1013807851, states[0] = -13.768313, states[40]= 0.000306
Saving checkpoint... 
Iteration: 1029240845, states[0] = 29.033482, states[40]= 0.056977
Saving checkpoint... 
Iteration: 1045727256, states[0] = -84.989963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1062200781, states[0] = -84.636075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1077614113, states[0] = 8.741796, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1094027658, states[0] = -84.509427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1109560607, states[0] = 28.811159, states[40]= 0.428325
Saving checkpoint... 
Iteration: 1126614317, states[0] = 4.571657, states[40]= 0.000129
Saving checkpoint... 
Iteration: 1142113442, states[0] = 3.978749, states[40]= 0.000141
Saving checkpoint... 
Iteration: 1155825323, states[0] = -57.049081, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1174437515, states[0] = 8.934787, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1190975986, states[0] = -40.466398, states[40]= 0.000198
Saving checkpoint... 
Iteration: 1206713893, states[0] = 34.506514, states[40]= 0.952005
Saving checkpoint... 
Iteration: 1224109272, states[0] = 0.135931, states[40]= 0.000228
Saving checkpoint... 
Iteration: 1241830906, states[0] = -77.671412, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1259926422, states[0] = 10.834559, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1277966929, states[0] = -39.978134, states[40]= 0.000203
Saving checkpoint... 
Iteration: 1294999037, states[0] = -83.086253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1312379626, states[0] = 29.136564, states[40]= 0.048520
Saving checkpoint... 
Iteration: 1329320505, states[0] = -75.447098, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1345215281, states[0] = 29.418770, states[40]= 0.006086
Saving checkpoint... 
Iteration: 1359291155, states[0] = -38.688451, states[40]= 0.000220
Saving checkpoint... 
Iteration: 1377799785, states[0] = -52.523015, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1395200631, states[0] = 28.182172, states[40]= 0.215291
Saving checkpoint... 
Iteration: 1410125758, states[0] = -47.059147, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1427561557, states[0] = 20.420708, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1442083623, states[0] = 3.827161, states[40]= 0.000145
Saving checkpoint... 
Iteration: 1456962478, states[0] = -57.846736, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1472717205, states[0] = 24.012200, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1486990859, states[0] = -84.585269, states[40]= 0.000001
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.852497
 - CaMKt in component CaMK (millimolar): 0.216473
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.272854
 - nass in component intracellular_ions (millimolar): 7.273206
 - ki in component intracellular_ions (millimolar): 143.848906
 - kss in component intracellular_ions (millimolar): 143.848871
 - cansr in component intracellular_ions (millimolar): 3.330899
 - cajsr in component intracellular_ions (millimolar): 1.922885
 - cai in component intracellular_ions (millimolar): 0.000161
 - m in component INa (dimensionless): 0.009952
 - hf in component INa (dimensionless): 0.584473
 - hs in component INa (dimensionless): 0.583423
 - j in component INa (dimensionless): 0.553451
 - hsp in component INa (dimensionless): 0.331858
 - jp in component INa (dimensionless): 0.511411
 - mL in component INaL (dimensionless): 0.000334
 - hL in component INaL (dimensionless): 0.182516
 - hLp in component INaL (dimensionless): 0.074406
 - a in component Ito (dimensionless): 0.001228
 - iF in component Ito (dimensionless): 0.999238
 - iS in component Ito (dimensionless): 0.130809
 - ap in component Ito (dimensionless): 0.000626
 - iFp in component Ito (dimensionless): 0.999239
 - iSp in component Ito (dimensionless): 0.146197
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.676714
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.928458
 - jca in component ICaL (dimensionless): 0.911014
 - ffp in component ICaL (dimensionless): 0.998906
 - fcafp in component ICaL (dimensionless): 0.999939
 - nca in component ICaL (dimensionless): 0.041850
 - xrf in component IKr (dimensionless): 0.101634
 - xrs in component IKr (dimensionless): 0.873107
 - xs1 in component IKs (dimensionless): 0.571190
 - xs2 in component IKs (dimensionless): 0.007293
 - xk1 in component IK1 (dimensionless): 0.996735
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
14:41:09 (82186): called boinc_finish(0)

</stderr_txt>
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