𝕏

Task 56270093

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_333-conf_771_0
Workunit 26726500
Created 4 Jul 2024, 22:36:40 UTC
Sent 5 Jul 2024, 16:33:59 UTC
Report deadline 8 Jul 2024, 16:33:59 UTC
Received 6 Jul 2024, 12:07:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241457
Run time 2 hours 3 min 53 sec
CPU time 2 hours 2 min 36 sec
Validate state Valid
Credit 47.65
Device peak FLOPS 3.42 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.77 MB
Peak swap size 6.14 MB
Peak disk usage 0.12 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_333-conf_771.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_333-conf_771_0_r12268919_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_333-conf_771_0_r12268919_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.971816
     * GNaL_b in INaL: 0.005874
     * Gto_b in Ito: 0.085049
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031889
     * GKs_b in IKs: 0.001927
     * GK1_b in IK1: 0.162651
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.100477
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032852
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9276530, states[0] = -60.101410, states[40]= 0.000039
Saving checkpoint... 
Iteration: 14464493, states[0] = -83.710313, states[40]= 0.000001
Saving checkpoint... 
Iteration: 23891694, states[0] = 5.511627, states[40]= 0.000299
Saving checkpoint... 
Iteration: 28925202, states[0] = -37.056532, states[40]= 0.000359
Saving checkpoint... 
Iteration: 34298610, states[0] = -84.182454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 47876615, states[0] = 14.297734, states[40]= 0.000023
Saving checkpoint... 
Iteration: 61598299, states[0] = -51.959603, states[40]= 0.000082
Saving checkpoint... 
Iteration: 75218812, states[0] = 5.306552, states[40]= 0.000121
Saving checkpoint... 
Iteration: 88637656, states[0] = -84.803107, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102115521, states[0] = -81.637437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 115755125, states[0] = -47.149771, states[40]= 0.000115
Saving checkpoint... 
Iteration: 129411870, states[0] = -35.871290, states[40]= 0.000243
Saving checkpoint... 
Iteration: 143101487, states[0] = -69.309797, states[40]= 0.000010
Saving checkpoint... 
Iteration: 156693415, states[0] = 17.507698, states[40]= 0.000006
Saving checkpoint... 
Iteration: 170328996, states[0] = 29.360741, states[40]= 0.024668
Saving checkpoint... 
Iteration: 183682235, states[0] = 22.476242, states[40]= 0.000012
Saving checkpoint... 
Iteration: 197367486, states[0] = 9.683644, states[40]= 0.000047
Saving checkpoint... 
Iteration: 210037907, states[0] = 5.692637, states[40]= 0.000100
Saving checkpoint... 
Iteration: 223515236, states[0] = 20.411047, states[40]= 0.000005
Saving checkpoint... 
Iteration: 232536427, states[0] = 5.035452, states[40]= 0.000112
Saving checkpoint... 
Iteration: 246219199, states[0] = -15.839031, states[40]= 0.000270
Saving checkpoint... 
Iteration: 259980630, states[0] = 28.053815, states[40]= 0.233132
Saving checkpoint... 
Iteration: 273644241, states[0] = 28.649171, states[40]= 0.426037
Saving checkpoint... 
Iteration: 287226041, states[0] = -31.378313, states[40]= 0.000270
Saving checkpoint... 
Iteration: 300715430, states[0] = -18.297956, states[40]= 0.000253
Saving checkpoint... 
Iteration: 314296700, states[0] = -84.990844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 327825451, states[0] = 26.924150, states[40]= 0.000284
Saving checkpoint... 
Iteration: 341221292, states[0] = -32.253262, states[40]= 0.000265
Saving checkpoint... 
Iteration: 354836872, states[0] = 19.569240, states[40]= 0.000005
Saving checkpoint... 
Iteration: 368396206, states[0] = -46.866242, states[40]= 0.000116
Saving checkpoint... 
Iteration: 382049789, states[0] = -31.224972, states[40]= 0.000270
Saving checkpoint... 
Iteration: 395646300, states[0] = 28.859721, states[40]= 0.002238
Saving checkpoint... 
Iteration: 409271234, states[0] = -84.779908, states[40]= 0.000001
Saving checkpoint... 
Iteration: 422920183, states[0] = -83.412582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 436589945, states[0] = -84.287062, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450174425, states[0] = 10.514921, states[40]= 0.000039
Saving checkpoint... 
Iteration: 463836885, states[0] = 12.549741, states[40]= 0.000024
Saving checkpoint... 
Iteration: 477474266, states[0] = 28.029554, states[40]= 0.000805
Saving checkpoint... 
Iteration: 491116810, states[0] = -85.025491, states[40]= 0.000001
Saving checkpoint... 
Iteration: 504261234, states[0] = -84.765348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 517723867, states[0] = -59.303255, states[40]= 0.000034
Saving checkpoint... 
Iteration: 531380154, states[0] = -47.170907, states[40]= 0.000113
Saving checkpoint... 
Iteration: 544412136, states[0] = -84.238430, states[40]= 0.000001
Saving checkpoint... 
Iteration: 558110875, states[0] = -82.052914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571756561, states[0] = -84.795322, states[40]= 0.000001
Saving checkpoint... 
Iteration: 585210423, states[0] = -50.237603, states[40]= 0.000086
Saving checkpoint... 
Iteration: 598953947, states[0] = 29.456677, states[40]= 0.016062
Saving checkpoint... 
Iteration: 612646057, states[0] = 18.593998, states[40]= 0.000005
Saving checkpoint... 
Iteration: 626293356, states[0] = 27.807397, states[40]= 0.000638
Saving checkpoint... 
Iteration: 639868743, states[0] = -46.424472, states[40]= 0.000120
Saving checkpoint... 
Iteration: 653548539, states[0] = -66.419237, states[40]= 0.000015
Saving checkpoint... 
Iteration: 667101461, states[0] = 34.994856, states[40]= 1.172296
Saving checkpoint... 
Iteration: 680711876, states[0] = -65.494999, states[40]= 0.000017
Saving checkpoint... 
Iteration: 694374844, states[0] = -62.084293, states[40]= 0.000025
Saving checkpoint... 
Iteration: 708020881, states[0] = -36.198070, states[40]= 0.000236
Saving checkpoint... 
Iteration: 721779983, states[0] = 28.952655, states[40]= 0.002558
Saving checkpoint... 
Iteration: 735434154, states[0] = 28.207468, states[40]= 0.157582
Saving checkpoint... 
Iteration: 749032420, states[0] = -56.998978, states[40]= 0.000044
Saving checkpoint... 
Iteration: 762625385, states[0] = 21.906972, states[40]= 0.000009
Saving checkpoint... 
Iteration: 776293411, states[0] = 20.351434, states[40]= 0.000005
Saving checkpoint... 
Iteration: 789878383, states[0] = -80.357173, states[40]= 0.000002
Saving checkpoint... 
Iteration: 803366306, states[0] = -65.525383, states[40]= 0.000017
Saving checkpoint... 
Iteration: 815656974, states[0] = -8.206671, states[40]= 0.000318
Saving checkpoint... 
Iteration: 829283287, states[0] = 23.059001, states[40]= 0.000017
Saving checkpoint... 
Iteration: 842923817, states[0] = 28.309500, states[40]= 0.135385
Saving checkpoint... 
Iteration: 856498623, states[0] = -26.041518, states[40]= 0.000264
Saving checkpoint... 
Iteration: 870159127, states[0] = -19.194904, states[40]= 0.000250
Saving checkpoint... 
Iteration: 883840536, states[0] = -41.380275, states[40]= 0.000177
Saving checkpoint... 
Iteration: 897496004, states[0] = -28.103147, states[40]= 0.000270
Saving checkpoint... 
Iteration: 911142746, states[0] = -2.323394, states[40]= 0.000262
Saving checkpoint... 
Iteration: 924850915, states[0] = -60.798137, states[40]= 0.000029
Saving checkpoint... 
Iteration: 938426661, states[0] = 28.519194, states[40]= 0.001388
Saving checkpoint... 
Iteration: 952145992, states[0] = -11.971142, states[40]= 0.000301
Saving checkpoint... 
Iteration: 965786463, states[0] = 12.718730, states[40]= 0.000023
Saving checkpoint... 
Iteration: 979491163, states[0] = -32.707874, states[40]= 0.000263
Saving checkpoint... 
Iteration: 993133637, states[0] = -1.306948, states[40]= 0.000242
Saving checkpoint... 
Iteration: 1006624511, states[0] = 6.051769, states[40]= 0.000094
Saving checkpoint... 
Iteration: 1020108481, states[0] = 16.630600, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1033767358, states[0] = 20.534005, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1047570698, states[0] = 28.499387, states[40]= 0.105257
Saving checkpoint... 
Iteration: 1061248446, states[0] = 28.298912, states[40]= 0.001062
Saving checkpoint... 
Iteration: 1074690099, states[0] = -83.816005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1088324710, states[0] = -47.461550, states[40]= 0.000110
Saving checkpoint... 
Iteration: 1101989074, states[0] = -46.235192, states[40]= 0.000122
Saving checkpoint... 
Iteration: 1115363958, states[0] = -84.671084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1129035476, states[0] = -84.779985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142350276, states[0] = -83.870488, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156041340, states[0] = -84.888332, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1169838208, states[0] = -77.971915, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1183391027, states[0] = 28.666437, states[40]= 0.084886
Saving checkpoint... 
Iteration: 1197033329, states[0] = -84.838182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1210528701, states[0] = -84.793973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224084065, states[0] = 19.118261, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1237730367, states[0] = 28.434410, states[40]= 0.001241
Saving checkpoint... 
Iteration: 1251264186, states[0] = 8.104152, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1264814679, states[0] = -57.647148, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1278308378, states[0] = -50.970869, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1291966205, states[0] = -41.105679, states[40]= 0.000180
Saving checkpoint... 
Iteration: 1305556625, states[0] = 28.521417, states[40]= 0.001380
Saving checkpoint... 
Iteration: 1318896279, states[0] = 25.469878, states[40]= 0.000088
Saving checkpoint... 
Iteration: 1332431768, states[0] = 0.057681, states[40]= 0.000213
Saving checkpoint... 
Iteration: 1345825866, states[0] = -82.472696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1359520656, states[0] = -84.871546, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1373075995, states[0] = 14.812786, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1386552329, states[0] = 27.182170, states[40]= 0.000349
Saving checkpoint... 
Iteration: 1395794041, states[0] = -47.541797, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1409321687, states[0] = -83.362515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422844616, states[0] = -84.830835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1436548295, states[0] = 26.782147, states[40]= 0.000247
Saving checkpoint... 
Iteration: 1445947998, states[0] = -37.362169, states[40]= 0.000223
Saving checkpoint... 
Iteration: 1459514223, states[0] = -84.905748, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1468941795, states[0] = -32.098614, states[40]= 0.000266
Saving checkpoint... 
Iteration: 1478372031, states[0] = 28.707884, states[40]= 0.001744
Saving checkpoint... 
Iteration: 1487818886, states[0] = -84.282789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1497218550, states[0] = 21.944513, states[40]= 0.000009
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.845967
 - CaMKt in component CaMK (millimolar): 0.217814
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.294208
 - nass in component intracellular_ions (millimolar): 7.294562
 - ki in component intracellular_ions (millimolar): 143.818800
 - kss in component intracellular_ions (millimolar): 143.818765
 - cansr in component intracellular_ions (millimolar): 3.342883
 - cajsr in component intracellular_ions (millimolar): 1.926211
 - cai in component intracellular_ions (millimolar): 0.000162
 - m in component INa (dimensionless): 0.009958
 - hf in component INa (dimensionless): 0.584212
 - hs in component INa (dimensionless): 0.583151
 - j in component INa (dimensionless): 0.553370
 - hsp in component INa (dimensionless): 0.331612
 - jp in component INa (dimensionless): 0.511532
 - mL in component INaL (dimensionless): 0.000335
 - hL in component INaL (dimensionless): 0.182804
 - hLp in component INaL (dimensionless): 0.074536
 - a in component Ito (dimensionless): 0.001228
 - iF in component Ito (dimensionless): 0.999237
 - iS in component Ito (dimensionless): 0.131123
 - ap in component Ito (dimensionless): 0.000626
 - iFp in component Ito (dimensionless): 0.999238
 - iSp in component Ito (dimensionless): 0.146595
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.677474
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.928924
 - jca in component ICaL (dimensionless): 0.911380
 - ffp in component ICaL (dimensionless): 0.998925
 - fcafp in component ICaL (dimensionless): 0.999940
 - nca in component ICaL (dimensionless): 0.042251
 - xrf in component IKr (dimensionless): 0.101037
 - xrs in component IKr (dimensionless): 0.872599
 - xs1 in component IKs (dimensionless): 0.570621
 - xs2 in component IKs (dimensionless): 0.007214
 - xk1 in component IK1 (dimensionless): 0.996736
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
07:07:19 (14452): called boinc_finish(0)

</stderr_txt>
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