𝕏

Task 56268476

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_2000-conf_870_1
Workunit 26725691
Created 4 Jul 2024, 22:35:47 UTC
Sent 5 Jul 2024, 16:20:06 UTC
Report deadline 8 Jul 2024, 16:20:06 UTC
Received 6 Jul 2024, 11:49:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237279
Run time 1 hours 34 min 59 sec
CPU time 1 hours 14 min 20 sec
Validate state Valid
Credit 43.81
Device peak FLOPS 3.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 9.91 MB
Peak swap size 5.26 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_2000-conf_870.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_2000-conf_870_1_r1008701084_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_2000-conf_870_1_r1008701084_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.124325
     * GNaL_b in INaL: 0.005909
     * Gto_b in Ito: 0.085045
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031982
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.163297
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.130536
     * GKb_b in IKb: 0.003796
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032231
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 6197338, states[0] = -92.575083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 13515039, states[0] = -94.166802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24897187, states[0] = -94.141401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33106358, states[0] = -1.539936, states[40]= 0.003515
Saving checkpoint... 
Iteration: 42336185, states[0] = -93.947635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48808048, states[0] = -94.129418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56823751, states[0] = -94.128910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66668827, states[0] = -94.130436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75803833, states[0] = -94.130622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80908118, states[0] = -94.126654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88025382, states[0] = 30.906690, states[40]= 0.000362
Saving checkpoint... 
Iteration: 97446653, states[0] = -94.077057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108584669, states[0] = -94.124954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119987959, states[0] = -94.123926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131774165, states[0] = -94.133085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143478884, states[0] = -94.095550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154384770, states[0] = -94.023074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163522901, states[0] = -94.112152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170062135, states[0] = 19.262033, states[40]= 0.000677
Saving checkpoint... 
Iteration: 176003989, states[0] = 34.469070, states[40]= 0.475045
Saving checkpoint... 
Iteration: 184580996, states[0] = -94.124912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191911744, states[0] = -94.128010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199396884, states[0] = -94.036575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208945068, states[0] = -94.126331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219123330, states[0] = -15.426954, states[40]= 0.001652
Saving checkpoint... 
Iteration: 225804062, states[0] = -94.132312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230808546, states[0] = -94.132151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238677584, states[0] = -94.132933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246488670, states[0] = -94.099736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257468951, states[0] = -94.090478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268393813, states[0] = -94.033024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279598993, states[0] = -94.127050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291151644, states[0] = -38.673821, states[40]= 0.000878
Saving checkpoint... 
Iteration: 302896336, states[0] = -94.128282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314590144, states[0] = -94.125726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326351214, states[0] = -93.975189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337353723, states[0] = -93.979254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347816397, states[0] = -94.131350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358325747, states[0] = -93.926646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369190977, states[0] = -74.844560, states[40]= 0.000004
Saving checkpoint... 
Iteration: 380137080, states[0] = -26.908261, states[40]= 0.001968
Saving checkpoint... 
Iteration: 391495500, states[0] = -94.101833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397914334, states[0] = -94.126971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404530585, states[0] = -94.113370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411575475, states[0] = -94.123031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422310238, states[0] = -93.889983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434355328, states[0] = -93.981359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442807044, states[0] = -94.131194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454016364, states[0] = 31.726176, states[40]= 0.006555
Saving checkpoint... 
Iteration: 463538940, states[0] = -94.115269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470904739, states[0] = -94.127072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477019833, states[0] = 31.625952, states[40]= 0.002005
Saving checkpoint... 
Iteration: 483006223, states[0] = 30.749836, states[40]= 0.220972
Saving checkpoint... 
Iteration: 487530839, states[0] = -94.113035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496951140, states[0] = -94.124677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506234216, states[0] = -93.601833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516204720, states[0] = -91.051376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526228870, states[0] = -93.571943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534410078, states[0] = -94.047999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545810375, states[0] = -94.130585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557509536, states[0] = -94.106175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569463804, states[0] = -94.086249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581259354, states[0] = -93.719656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592889282, states[0] = -94.127196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603175991, states[0] = -59.475847, states[40]= 0.000047
Saving checkpoint... 
Iteration: 613251653, states[0] = -93.685782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623681158, states[0] = -94.131188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634455324, states[0] = -94.081138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645495705, states[0] = -94.100674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653975180, states[0] = -94.122695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665450646, states[0] = -94.078165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677188647, states[0] = -72.014302, states[40]= 0.000006
Saving checkpoint... 
Iteration: 688685074, states[0] = -94.130978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699652506, states[0] = -94.129637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710022640, states[0] = 31.327884, states[40]= 0.000801
Saving checkpoint... 
Iteration: 720160773, states[0] = -46.321830, states[40]= 0.000338
Saving checkpoint... 
Iteration: 730859526, states[0] = -94.127833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742049412, states[0] = 23.975424, states[40]= 0.000322
Saving checkpoint... 
Iteration: 753751281, states[0] = -94.130964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765095937, states[0] = 4.389215, states[40]= 0.002983
Saving checkpoint... 
Iteration: 776668359, states[0] = -94.130005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787334907, states[0] = -93.943412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798104345, states[0] = -0.449616, states[40]= 0.003399
Saving checkpoint... 
Iteration: 808614458, states[0] = -94.126204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820183835, states[0] = -66.815216, states[40]= 0.000014
Saving checkpoint... 
Iteration: 831494459, states[0] = -94.099272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842813061, states[0] = -94.129049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854300597, states[0] = -93.862108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865427271, states[0] = -94.060953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875222616, states[0] = -93.522053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885156394, states[0] = -42.615149, states[40]= 0.000549
Saving checkpoint... 
Iteration: 893831482, states[0] = -94.128152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904033505, states[0] = 29.036992, states[40]= 0.000141
Saving checkpoint... 
Iteration: 914505546, states[0] = -94.103042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925880870, states[0] = -94.125953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937144630, states[0] = -32.965677, states[40]= 0.001528
Saving checkpoint... 
Iteration: 948706789, states[0] = -94.130099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956842412, states[0] = -94.127426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967798285, states[0] = -94.128901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975560580, states[0] = -94.117588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986984927, states[0] = -94.120571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998260258, states[0] = -93.721386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009896107, states[0] = -94.124847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021477763, states[0] = -94.091101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032867443, states[0] = -94.126022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043374347, states[0] = -94.005957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053603739, states[0] = -94.123851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064296507, states[0] = -93.849344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073481580, states[0] = -94.092612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080714703, states[0] = -94.129519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089576116, states[0] = -94.119830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096973956, states[0] = -94.120595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107199966, states[0] = -86.851203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116479724, states[0] = -94.091552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125013921, states[0] = 31.562977, states[40]= 0.015265
Saving checkpoint... 
Iteration: 1133353210, states[0] = -93.974507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136365516, states[0] = -93.993345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146658593, states[0] = -94.127771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154825707, states[0] = -94.127090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163173564, states[0] = -57.335468, states[40]= 0.000066
Saving checkpoint... 
Iteration: 1172474695, states[0] = -94.088895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182045907, states[0] = 25.193485, states[40]= 0.000261
Saving checkpoint... 
Iteration: 1190724369, states[0] = -94.129011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196637403, states[0] = -94.126267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206057721, states[0] = 20.943002, states[40]= 0.000526
Saving checkpoint... 
Iteration: 1213522150, states[0] = -94.107008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223459927, states[0] = -94.080911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233876418, states[0] = -94.124649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244588161, states[0] = -94.120915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255507880, states[0] = -94.102198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263486646, states[0] = -94.093924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269762085, states[0] = -94.128284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276186756, states[0] = -69.871644, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1283234586, states[0] = -93.599866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289606332, states[0] = -94.122996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297331918, states[0] = -93.934931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304003224, states[0] = 37.622854, states[40]= 0.611255
Saving checkpoint... 
Iteration: 1312283538, states[0] = -93.807478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318200059, states[0] = -86.955592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324005787, states[0] = 31.050692, states[40]= 0.256818
Saving checkpoint... 
Iteration: 1328825744, states[0] = -94.126240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334915347, states[0] = -94.122351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342427049, states[0] = -94.058446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350422441, states[0] = -94.054731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356413416, states[0] = -94.047000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362654547, states[0] = -94.126513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371643815, states[0] = -94.125846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381328812, states[0] = -93.928119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388777315, states[0] = -94.127397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396641319, states[0] = -94.125561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407514004, states[0] = -94.103516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418333096, states[0] = -93.936709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422743405, states[0] = -94.127789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432608965, states[0] = -94.122589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444111615, states[0] = -5.518049, states[40]= 0.003097
Saving checkpoint... 
Iteration: 1456116466, states[0] = -9.446195, states[40]= 0.002480
Saving checkpoint... 
Iteration: 1468114351, states[0] = -7.686039, states[40]= 0.002776
Saving checkpoint... 
Iteration: 1479934433, states[0] = -94.120712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491446510, states[0] = -94.071519, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.993232
 - CaMKt in component CaMK (millimolar): 0.005751
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 6.849775
 - nass in component intracellular_ions (millimolar): 6.849893
 - ki in component intracellular_ions (millimolar): 144.987425
 - kss in component intracellular_ions (millimolar): 144.987411
 - cansr in component intracellular_ions (millimolar): 1.847861
 - cajsr in component intracellular_ions (millimolar): 1.846993
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003966
 - hf in component INa (dimensionless): 0.863319
 - hs in component INa (dimensionless): 0.863321
 - j in component INa (dimensionless): 0.863333
 - hsp in component INa (dimensionless): 0.695182
 - jp in component INa (dimensionless): 0.863340
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.704441
 - hLp in component INaL (dimensionless): 0.492042
 - a in component Ito (dimensionless): 0.000663
 - iF in component Ito (dimensionless): 0.999847
 - iS in component Ito (dimensionless): 0.886366
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999847
 - iSp in component Ito (dimensionless): 0.925981
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.971305
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004568
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.110579
 - xs1 in component IKs (dimensionless): 0.135755
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997566
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:16:35 (8096): called boinc_finish(0)

</stderr_txt>
]]>


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