𝕏

Task 56259385

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pueyo_APDR-conf_61_1
Workunit 26721148
Created 4 Jul 2024, 22:30:48 UTC
Sent 5 Jul 2024, 15:15:03 UTC
Report deadline 9 Jul 2024, 0:51:03 UTC
Received 6 Jul 2024, 12:53:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215634
Run time 1 hours 13 min 4 sec
CPU time 1 hours 12 min 43 sec
Validate state Valid
Credit 62.08
Device peak FLOPS 4.83 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.32 MB
Peak swap size 6.30 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pueyo_APDR-conf_61.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pueyo_APDR-conf_61_1_r1283301002_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pueyo_APDR-conf_61_1_r1283301002_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.083591
     * GNaL_b in INaL: 0.005840
     * Gto_b in Ito: 0.085513
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031786
     * GKs_b in IKs: 0.001922
     * GK1_b in IK1: 0.163401
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.226324
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033870
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13413409, states[0] = -95.102726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32773493, states[0] = -94.985890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51889498, states[0] = -95.036224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70992711, states[0] = -95.047928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90296810, states[0] = -94.971939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109651420, states[0] = -74.540595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122435209, states[0] = -95.028475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141174119, states[0] = -94.674944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160211711, states[0] = -94.857302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179043916, states[0] = 14.002450, states[40]= 0.005072
Saving checkpoint... 
Iteration: 197858465, states[0] = -95.002000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210509425, states[0] = 23.234558, states[40]= 0.060319
Saving checkpoint... 
Iteration: 228317990, states[0] = -94.980076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246195772, states[0] = -94.824826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264417050, states[0] = -95.021432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282926566, states[0] = -95.023705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305274826, states[0] = -94.944829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324931538, states[0] = -95.024784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342850369, states[0] = -94.997914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361407094, states[0] = -95.018691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379347794, states[0] = -94.996651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396569310, states[0] = 3.501739, states[40]= 0.004597
Saving checkpoint... 
Iteration: 414285978, states[0] = -94.955323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431849377, states[0] = -94.997379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449286947, states[0] = -94.956164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466923382, states[0] = -95.022812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484460126, states[0] = -95.030220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501988222, states[0] = -95.034388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519371574, states[0] = -95.006894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537354271, states[0] = -94.999599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549491062, states[0] = -95.034721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567154965, states[0] = -79.932262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584531507, states[0] = 18.266193, states[40]= 0.005832
Saving checkpoint... 
Iteration: 602227896, states[0] = -94.884213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619734760, states[0] = -94.894913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637165560, states[0] = -93.229861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649365807, states[0] = -95.004514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667153676, states[0] = -77.727225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684775892, states[0] = -94.945633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702507350, states[0] = 24.465753, states[40]= 0.097670
Saving checkpoint... 
Iteration: 720374941, states[0] = -95.008047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738474167, states[0] = -95.032282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756662377, states[0] = -91.058234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774535668, states[0] = 16.928023, states[40]= 0.005455
Saving checkpoint... 
Iteration: 792454777, states[0] = -95.029091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810544997, states[0] = 13.609959, states[40]= 0.005044
Saving checkpoint... 
Iteration: 828749429, states[0] = -94.915363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846794777, states[0] = -94.962581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864622118, states[0] = -40.108848, states[40]= 0.000128
Saving checkpoint... 
Iteration: 882690522, states[0] = -94.812860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900781345, states[0] = -94.950757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918661794, states[0] = -90.469616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936714991, states[0] = -94.861887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954917020, states[0] = -95.020933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972305923, states[0] = -94.971138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990156832, states[0] = -83.183137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007991159, states[0] = -95.034436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025942901, states[0] = -95.026705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043546642, states[0] = 12.994451, states[40]= 0.005008
Saving checkpoint... 
Iteration: 1060814399, states[0] = -94.977035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079539793, states[0] = 15.504883, states[40]= 0.005220
Saving checkpoint... 
Iteration: 1099267207, states[0] = -94.936347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118130391, states[0] = -48.635538, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1137088827, states[0] = -8.885400, states[40]= 0.002558
Saving checkpoint... 
Iteration: 1156505668, states[0] = 26.698160, states[40]= 0.135945
Saving checkpoint... 
Iteration: 1169148372, states[0] = -69.592283, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1186837307, states[0] = -94.990762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205358947, states[0] = -95.001253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223714943, states[0] = -94.861613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236600333, states[0] = -19.350231, states[40]= 0.001013
Saving checkpoint... 
Iteration: 1255351391, states[0] = -94.997799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273369189, states[0] = -95.005470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291839482, states[0] = -94.991851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310078629, states[0] = -1.542740, states[40]= 0.004013
Saving checkpoint... 
Iteration: 1328538759, states[0] = 15.869259, states[40]= 0.005269
Saving checkpoint... 
Iteration: 1346767451, states[0] = -94.936450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365097023, states[0] = -16.239430, states[40]= 0.001305
Saving checkpoint... 
Iteration: 1382935620, states[0] = -95.024976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401423159, states[0] = -95.022153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419907572, states[0] = -95.018134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438125702, states[0] = -43.727896, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1456494155, states[0] = -95.034518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474995834, states[0] = -95.034710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493886697, states[0] = -95.011719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512594596, states[0] = -95.264701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530952785, states[0] = 6.561299, states[40]= 0.005453
Saving checkpoint... 
Iteration: 1549238030, states[0] = 13.810071, states[40]= 0.006174
Saving checkpoint... 
Iteration: 1567511687, states[0] = 23.219556, states[40]= 0.037017
Saving checkpoint... 
Iteration: 1585631730, states[0] = -79.399934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604646474, states[0] = -95.266370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623456613, states[0] = -95.082526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642026476, states[0] = -70.825708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1660301940, states[0] = -39.792710, states[40]= 0.000136
Saving checkpoint... 
Iteration: 1678785948, states[0] = -95.304787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697532530, states[0] = -81.406835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716323566, states[0] = 19.628093, states[40]= 0.008691
Saving checkpoint... 
Iteration: 1735218432, states[0] = 21.273307, states[40]= 0.012677
Saving checkpoint... 
Iteration: 1748978944, states[0] = -95.299601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767561027, states[0] = -95.283973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1785902981, states[0] = 38.101942, states[40]= 0.111213
Saving checkpoint... 
Iteration: 1803933389, states[0] = -95.080929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822284840, states[0] = -94.989387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840248325, states[0] = -94.935097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858015599, states[0] = 21.866395, states[40]= 0.016526
Saving checkpoint... 
Iteration: 1876266201, states[0] = -94.942228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894691737, states[0] = -94.819297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913275286, states[0] = -94.946700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931251970, states[0] = -94.919351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949889939, states[0] = -95.013289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968713207, states[0] = -94.858398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987364253, states[0] = -95.003231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006394558, states[0] = -95.014036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025514968, states[0] = 22.064514, states[40]= 0.018474
Saving checkpoint... 
Iteration: 2044524645, states[0] = 20.177456, states[40]= 0.007137
Saving checkpoint... 
Iteration: 2063046387, states[0] = 13.090050, states[40]= 0.005013
Saving checkpoint... 
Iteration: 2081913840, states[0] = -95.019346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095044128, states[0] = 13.932454, states[40]= 0.005067
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.910627
 - CaMKt in component CaMK (millimolar): 0.007012
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.580450
 - nass in component intracellular_ions (millimolar): 6.580510
 - ki in component intracellular_ions (millimolar): 145.396740
 - kss in component intracellular_ions (millimolar): 145.396720
 - cansr in component intracellular_ions (millimolar): 1.313188
 - cajsr in component intracellular_ions (millimolar): 1.275107
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003615
 - hf in component INa (dimensionless): 0.880153
 - hs in component INa (dimensionless): 0.880148
 - j in component INa (dimensionless): 0.880119
 - hsp in component INa (dimensionless): 0.726117
 - jp in component INa (dimensionless): 0.880100
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710005
 - hLp in component INaL (dimensionless): 0.451831
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620689
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695477
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935022
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001605
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330627
 - xs1 in component IKs (dimensionless): 0.242394
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:15:01 (19008): called boinc_finish(0)

</stderr_txt>
]]>