𝕏

Task 56249977

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_8000-conf_552_0
Workunit 26716488
Created 4 Jul 2024, 22:25:15 UTC
Sent 5 Jul 2024, 14:25:57 UTC
Report deadline 8 Jul 2024, 14:25:57 UTC
Received 8 Jul 2024, 16:15:51 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227233
Run time 2 hours 43 min 43 sec
CPU time 1 hours 30 min 38 sec
Validate state Valid
Credit 46.75
Device peak FLOPS 3.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.06 MB
Peak swap size 392.01 GB
Peak disk usage 2.47 MB

Stderr output

<core_client_version>7.20.7</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_8000-conf_552.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_8000-conf_552_0_r1697489450_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_8000-conf_552_0_r1697489450_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.696835
     * GNaL_b in INaL: 0.005892
     * Gto_b in Ito: 0.084498
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031945
     * GKs_b in IKs: 0.001936
     * GK1_b in IK1: 0.163074
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.284589
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032557
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 375.000000
     * CL_0 in membrane: 8000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1496000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 15901354, states[0] = -84.087714, states[40]= 0.000001
Saving checkpoint... 
Iteration: 31657201, states[0] = -83.960797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 47332474, states[0] = -83.902289, states[40]= 0.000001
Saving checkpoint... 
Iteration: 62791051, states[0] = -83.873336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78762126, states[0] = -83.854231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 94607343, states[0] = -83.843268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 110129282, states[0] = -83.840674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125690100, states[0] = -83.843991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141312255, states[0] = -83.852790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 157067531, states[0] = -83.861388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 172762144, states[0] = -83.870069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188602192, states[0] = -83.856398, states[40]= 0.000001
Saving checkpoint... 
Iteration: 204521954, states[0] = -83.831985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 210874723, states[0] = -83.818572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 212913013, states[0] = -83.864604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 233073075, states[0] = -83.856776, states[40]= 0.000001
Saving checkpoint... 
Iteration: 252694499, states[0] = -83.865101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 268284861, states[0] = -83.447861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285082602, states[0] = -83.855678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301882986, states[0] = -83.828480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 318101529, states[0] = -83.824602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 333974066, states[0] = -83.826636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 350739258, states[0] = -83.817883, states[40]= 0.000001
Saving checkpoint... 
Iteration: 366296356, states[0] = -83.821861, states[40]= 0.000001
Saving checkpoint... 
Iteration: 382564861, states[0] = -83.819140, states[40]= 0.000001
Saving checkpoint... 
Iteration: 399009508, states[0] = -83.816204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 416098669, states[0] = 4.695297, states[40]= 0.000916
Saving checkpoint... 
Iteration: 432097727, states[0] = 5.124081, states[40]= 0.000883
Saving checkpoint... 
Iteration: 448277583, states[0] = -83.416509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464554494, states[0] = -83.841985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 480538508, states[0] = -83.836581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 496543876, states[0] = -83.838460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 512897725, states[0] = -83.863499, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529362234, states[0] = -83.842816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 545632847, states[0] = -83.833898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 561835275, states[0] = -83.828954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577960278, states[0] = -83.826478, states[40]= 0.000001
Saving checkpoint... 
Iteration: 594303357, states[0] = -83.821434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610087430, states[0] = -83.824312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 625830739, states[0] = -83.828963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641814127, states[0] = -83.829300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 657371394, states[0] = -83.842289, states[40]= 0.000001
Saving checkpoint... 
Iteration: 670293625, states[0] = -83.821444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703025500, states[0] = -83.815692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 740716791, states[0] = -83.864980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 776358890, states[0] = -83.664088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811879663, states[0] = -83.812847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 848203836, states[0] = -80.363627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874855223, states[0] = -83.816375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 893603512, states[0] = -83.834246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909529712, states[0] = -83.836443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 925586523, states[0] = -83.834695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 941484277, states[0] = -83.837871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 957217405, states[0] = -83.848254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 973341455, states[0] = -83.843017, states[40]= 0.000001
Saving checkpoint... 
Iteration: 989326138, states[0] = -83.843604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1005317305, states[0] = -83.843938, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1021796673, states[0] = -83.829165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1056959086, states[0] = -83.860213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1092278589, states[0] = -83.419958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129655513, states[0] = -83.832480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166764378, states[0] = -83.816545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188559990, states[0] = -83.842656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1213038926, states[0] = -83.856280, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228197394, states[0] = -75.460254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263517585, states[0] = -83.813079, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1290026631, states[0] = -83.824350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1305569991, states[0] = -83.834664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320651265, states[0] = -83.859700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1335945367, states[0] = -83.812002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351286968, states[0] = -83.813698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1366791493, states[0] = -83.816093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1382470665, states[0] = -83.818588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1398036837, states[0] = -83.824033, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1413495741, states[0] = -83.836845, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1428948162, states[0] = -83.860186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1444386805, states[0] = -83.712143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459464232, states[0] = -83.812965, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474702710, states[0] = -83.816546, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1490374766, states[0] = -83.819405, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.687664
 - CaMKt in component CaMK (millimolar): 0.000865
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 6.090253
 - nass in component intracellular_ions (millimolar): 6.090360
 - ki in component intracellular_ions (millimolar): 145.814314
 - kss in component intracellular_ions (millimolar): 145.814305
 - cansr in component intracellular_ions (millimolar): 1.647080
 - cajsr in component intracellular_ions (millimolar): 1.647080
 - cai in component intracellular_ions (millimolar): 0.000095
 - m in component INa (dimensionless): 0.011184
 - hf in component INa (dimensionless): 0.537380
 - hs in component INa (dimensionless): 0.537380
 - j in component INa (dimensionless): 0.537381
 - hsp in component INa (dimensionless): 0.295477
 - jp in component INa (dimensionless): 0.537381
 - mL in component INaL (dimensionless): 0.000417
 - hL in component INaL (dimensionless): 0.375843
 - hLp in component INaL (dimensionless): 0.208309
 - a in component Ito (dimensionless): 0.001328
 - iF in component Ito (dimensionless): 0.999072
 - iS in component Ito (dimensionless): 0.998872
 - ap in component Ito (dimensionless): 0.000677
 - iFp in component Ito (dimensionless): 0.999072
 - iSp in component Ito (dimensionless): 0.998992
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999938
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003641
 - xrf in component IKr (dimensionless): 0.000015
 - xrs in component IKr (dimensionless): 0.001023
 - xs1 in component IKs (dimensionless): 0.005946
 - xs2 in component IKs (dimensionless): 0.000308
 - xk1 in component IK1 (dimensionless): 0.996991
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
18:15:36 (41233): called boinc_finish(0)

</stderr_txt>
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