𝕏

Task 56245452

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_348_1
Workunit 26714225
Created 4 Jul 2024, 22:22:22 UTC
Sent 5 Jul 2024, 13:49:46 UTC
Report deadline 8 Jul 2024, 13:49:46 UTC
Received 6 Jul 2024, 10:23:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241172
Run time 1 hours 22 min 58 sec
CPU time 1 hours 17 min 53 sec
Validate state Valid
Credit 42.42
Device peak FLOPS 4.28 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.18 MB
Peak swap size 6.22 MB
Peak disk usage 0.12 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_348.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_348_1_r220179690_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_348_1_r220179690_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.095228
     * GNaL_b in INaL: 0.005833
     * Gto_b in Ito: 0.084811
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031722
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.163433
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.226252
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032114
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8369543, states[0] = 8.365810, states[40]= 0.007077
Saving checkpoint... 
Iteration: 20834182, states[0] = 34.364647, states[40]= 0.096589
Saving checkpoint... 
Iteration: 33458547, states[0] = -87.667230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45651693, states[0] = -87.777020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57767825, states[0] = -83.610370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69970481, states[0] = -87.742200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81578928, states[0] = -53.017300, states[40]= 0.000024
Saving checkpoint... 
Iteration: 93507598, states[0] = 19.827649, states[40]= 0.014874
Saving checkpoint... 
Iteration: 105383668, states[0] = -16.510070, states[40]= 0.001767
Saving checkpoint... 
Iteration: 117534629, states[0] = 1.029498, states[40]= 0.006237
Saving checkpoint... 
Iteration: 129541097, states[0] = -7.247741, states[40]= 0.004096
Saving checkpoint... 
Iteration: 141631325, states[0] = -87.750884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153744484, states[0] = -62.215554, states[40]= 0.000006
Saving checkpoint... 
Iteration: 165920094, states[0] = -79.245105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178220282, states[0] = -31.386165, states[40]= 0.000453
Saving checkpoint... 
Iteration: 190368051, states[0] = -6.890072, states[40]= 0.004204
Saving checkpoint... 
Iteration: 202782651, states[0] = -87.716008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214840723, states[0] = 13.801248, states[40]= 0.008270
Saving checkpoint... 
Iteration: 227109896, states[0] = -87.700047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238987847, states[0] = 21.843192, states[40]= 0.033054
Saving checkpoint... 
Iteration: 250955071, states[0] = -87.755718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259743748, states[0] = -78.782708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271562577, states[0] = -56.983064, states[40]= 0.000013
Saving checkpoint... 
Iteration: 283746309, states[0] = -84.751134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296071816, states[0] = -76.077806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 308421929, states[0] = -87.553103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320466266, states[0] = -87.811143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333005608, states[0] = 7.148881, states[40]= 0.007185
Saving checkpoint... 
Iteration: 344828298, states[0] = 13.457461, states[40]= 0.008186
Saving checkpoint... 
Iteration: 356829249, states[0] = 12.135825, states[40]= 0.007913
Saving checkpoint... 
Iteration: 368782905, states[0] = -87.776404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380783859, states[0] = -87.783098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392832368, states[0] = 7.583591, states[40]= 0.007242
Saving checkpoint... 
Iteration: 404910608, states[0] = -87.483372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417005697, states[0] = 0.061605, states[40]= 0.006043
Saving checkpoint... 
Iteration: 428552522, states[0] = -65.713630, states[40]= 0.000003
Saving checkpoint... 
Iteration: 440495140, states[0] = 6.940514, states[40]= 0.007157
Saving checkpoint... 
Iteration: 452562494, states[0] = -84.542167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464815829, states[0] = 13.738367, states[40]= 0.008254
Saving checkpoint... 
Iteration: 477087782, states[0] = -87.712444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488960788, states[0] = 22.746338, states[40]= 0.050124
Saving checkpoint... 
Iteration: 501379934, states[0] = -67.971931, states[40]= 0.000002
Saving checkpoint... 
Iteration: 513909363, states[0] = -87.671416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526193139, states[0] = -41.912916, states[40]= 0.000124
Saving checkpoint... 
Iteration: 534309303, states[0] = 13.484792, states[40]= 0.008192
Saving checkpoint... 
Iteration: 546441690, states[0] = -87.805473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558263230, states[0] = -87.773927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569819380, states[0] = 3.932972, states[40]= 0.006735
Saving checkpoint... 
Iteration: 582052381, states[0] = -86.230696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594462470, states[0] = 17.577698, states[40]= 0.010173
Saving checkpoint... 
Iteration: 606633115, states[0] = 14.822509, states[40]= 0.008566
Saving checkpoint... 
Iteration: 618983294, states[0] = 2.086747, states[40]= 0.006432
Saving checkpoint... 
Iteration: 631107257, states[0] = 31.183682, states[40]= 0.124525
Saving checkpoint... 
Iteration: 643256677, states[0] = -87.779925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655379542, states[0] = -86.635996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667252375, states[0] = -87.773898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679328746, states[0] = -20.066289, states[40]= 0.001259
Saving checkpoint... 
Iteration: 691576050, states[0] = -87.749521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703668260, states[0] = -32.116522, states[40]= 0.000419
Saving checkpoint... 
Iteration: 715630226, states[0] = 9.830860, states[40]= 0.007546
Saving checkpoint... 
Iteration: 727873687, states[0] = -86.976916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740037984, states[0] = -86.704428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751859950, states[0] = -76.726448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763895062, states[0] = -87.722822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775712933, states[0] = -87.639743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787758630, states[0] = 29.938718, states[40]= 0.125311
Saving checkpoint... 
Iteration: 799771662, states[0] = 19.242091, states[40]= 0.012970
Saving checkpoint... 
Iteration: 812079063, states[0] = -87.797364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824424166, states[0] = 25.028149, states[40]= 0.093373
Saving checkpoint... 
Iteration: 836493830, states[0] = -39.697440, states[40]= 0.000167
Saving checkpoint... 
Iteration: 848983770, states[0] = -27.553203, states[40]= 0.000656
Saving checkpoint... 
Iteration: 861014662, states[0] = -74.940806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 873479123, states[0] = -24.478248, states[40]= 0.000856
Saving checkpoint... 
Iteration: 885175325, states[0] = -68.715834, states[40]= 0.000002
Saving checkpoint... 
Iteration: 896796437, states[0] = -5.713471, states[40]= 0.004554
Saving checkpoint... 
Iteration: 908079910, states[0] = 30.000753, states[40]= 0.125329
Saving checkpoint... 
Iteration: 919826582, states[0] = -50.494484, states[40]= 0.000036
Saving checkpoint... 
Iteration: 932158994, states[0] = -50.937627, states[40]= 0.000033
Saving checkpoint... 
Iteration: 944431476, states[0] = 15.489845, states[40]= 0.008814
Saving checkpoint... 
Iteration: 956511494, states[0] = -84.020804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968817328, states[0] = -44.386863, states[40]= 0.000087
Saving checkpoint... 
Iteration: 981241538, states[0] = 25.361926, states[40]= 0.098078
Saving checkpoint... 
Iteration: 993017787, states[0] = -87.443978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004959240, states[0] = -14.950240, states[40]= 0.002062
Saving checkpoint... 
Iteration: 1016793573, states[0] = -18.043368, states[40]= 0.001523
Saving checkpoint... 
Iteration: 1025331031, states[0] = -74.013981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1037374794, states[0] = -87.748978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049553587, states[0] = -87.792047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061530265, states[0] = -87.715621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073433409, states[0] = 5.749059, states[40]= 0.006996
Saving checkpoint... 
Iteration: 1085715306, states[0] = -87.788176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098088111, states[0] = 12.347133, states[40]= 0.007952
Saving checkpoint... 
Iteration: 1109519487, states[0] = -87.688476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121693225, states[0] = -87.724916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133738413, states[0] = 19.176600, states[40]= 0.012796
Saving checkpoint... 
Iteration: 1146080143, states[0] = 14.259329, states[40]= 0.008392
Saving checkpoint... 
Iteration: 1158068785, states[0] = 19.403321, states[40]= 0.013430
Saving checkpoint... 
Iteration: 1170031209, states[0] = -87.759354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181908263, states[0] = 15.190816, states[40]= 0.008696
Saving checkpoint... 
Iteration: 1194083104, states[0] = 9.332084, states[40]= 0.007476
Saving checkpoint... 
Iteration: 1206013064, states[0] = -87.703689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217855164, states[0] = -87.743161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229712688, states[0] = 37.421127, states[40]= 0.096320
Saving checkpoint... 
Iteration: 1241767553, states[0] = -13.076522, states[40]= 0.002476
Saving checkpoint... 
Iteration: 1253147510, states[0] = -83.028889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265751080, states[0] = 2.837627, states[40]= 0.006561
Saving checkpoint... 
Iteration: 1277814338, states[0] = -85.299300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290264711, states[0] = -15.900807, states[40]= 0.001877
Saving checkpoint... 
Iteration: 1302387365, states[0] = 19.539081, states[40]= 0.013855
Saving checkpoint... 
Iteration: 1314738399, states[0] = 8.848726, states[40]= 0.007410
Saving checkpoint... 
Iteration: 1326841111, states[0] = -87.731295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339130322, states[0] = -69.395008, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1351298634, states[0] = -74.365128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1363732873, states[0] = 9.286128, states[40]= 0.007469
Saving checkpoint... 
Iteration: 1375834525, states[0] = -87.724681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387621502, states[0] = -62.875000, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1399564102, states[0] = 8.245780, states[40]= 0.007329
Saving checkpoint... 
Iteration: 1411365532, states[0] = 24.953439, states[40]= 0.092258
Saving checkpoint... 
Iteration: 1423215014, states[0] = 16.517609, states[40]= 0.009333
Saving checkpoint... 
Iteration: 1435357765, states[0] = 41.655471, states[40]= 0.046949
Saving checkpoint... 
Iteration: 1447381773, states[0] = 15.158063, states[40]= 0.008684
Saving checkpoint... 
Iteration: 1459389396, states[0] = 9.681808, states[40]= 0.007525
Saving checkpoint... 
Iteration: 1471646944, states[0] = -87.670341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483681443, states[0] = -87.804569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495662249, states[0] = -87.748210, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.689606
 - CaMKt in component CaMK (millimolar): 0.042378
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.010259
 - nass in component intracellular_ions (millimolar): 7.010407
 - ki in component intracellular_ions (millimolar): 144.910247
 - kss in component intracellular_ions (millimolar): 144.910215
 - cansr in component intracellular_ions (millimolar): 1.619353
 - cajsr in component intracellular_ions (millimolar): 1.187429
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007484
 - hf in component INa (dimensionless): 0.691557
 - hs in component INa (dimensionless): 0.691318
 - j in component INa (dimensionless): 0.680594
 - hsp in component INa (dimensionless): 0.446282
 - jp in component INa (dimensionless): 0.653807
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.291758
 - hLp in component INaL (dimensionless): 0.135415
 - a in component Ito (dimensionless): 0.001014
 - iF in component Ito (dimensionless): 0.999539
 - iS in component Ito (dimensionless): 0.175182
 - ap in component Ito (dimensionless): 0.000517
 - iFp in component Ito (dimensionless): 0.999539
 - iSp in component Ito (dimensionless): 0.211851
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.803509
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966637
 - jca in component ICaL (dimensionless): 0.947750
 - ffp in component ICaL (dimensionless): 0.999860
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009464
 - xrf in component IKr (dimensionless): 0.029099
 - xrs in component IKr (dimensionless): 0.788617
 - xs1 in component IKs (dimensionless): 0.459512
 - xs2 in component IKs (dimensionless): 0.001209
 - xk1 in component IK1 (dimensionless): 0.996814
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:18:03 (10408): called boinc_finish(0)

</stderr_txt>
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