𝕏

Task 56245448

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_148_1
Workunit 26714223
Created 4 Jul 2024, 22:22:22 UTC
Sent 5 Jul 2024, 13:49:23 UTC
Report deadline 8 Jul 2024, 13:49:23 UTC
Received 6 Jul 2024, 6:56:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 229683
Run time 1 hours 18 min 57 sec
CPU time 1 hours 7 min 51 sec
Validate state Valid
Credit 43.75
Device peak FLOPS 4.12 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.80 MB
Peak swap size 6.22 MB
Peak disk usage 0.12 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_148.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_148_1_r606720564_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_148_1_r606720564_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.043122
     * GNaL_b in INaL: 0.005785
     * Gto_b in Ito: 0.085377
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031903
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.163721
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.397886
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033774
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12916839, states[0] = -49.937204, states[40]= 0.000033
Saving checkpoint... 
Iteration: 25239444, states[0] = -36.535007, states[40]= 0.000241
Saving checkpoint... 
Iteration: 38668712, states[0] = 25.894990, states[40]= 0.103333
Saving checkpoint... 
Iteration: 50249196, states[0] = -53.921559, states[40]= 0.000021
Saving checkpoint... 
Iteration: 63303816, states[0] = -87.750614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76147438, states[0] = -87.790966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89495133, states[0] = 29.866864, states[40]= 0.124999
Saving checkpoint... 
Iteration: 102734516, states[0] = -40.889912, states[40]= 0.000142
Saving checkpoint... 
Iteration: 115809607, states[0] = -87.791803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129221953, states[0] = -27.185753, states[40]= 0.000675
Saving checkpoint... 
Iteration: 141686555, states[0] = 10.487980, states[40]= 0.007638
Saving checkpoint... 
Iteration: 154774201, states[0] = -87.645590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167548641, states[0] = -23.237544, states[40]= 0.000951
Saving checkpoint... 
Iteration: 180464601, states[0] = -87.775819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193770030, states[0] = -87.642161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207218069, states[0] = -32.657466, states[40]= 0.000394
Saving checkpoint... 
Iteration: 220543504, states[0] = -23.469700, states[40]= 0.000932
Saving checkpoint... 
Iteration: 233449217, states[0] = -87.739696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246503317, states[0] = 14.277172, states[40]= 0.008402
Saving checkpoint... 
Iteration: 259782330, states[0] = -87.748806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273049224, states[0] = -38.739259, states[40]= 0.000189
Saving checkpoint... 
Iteration: 286131113, states[0] = -87.807949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298907884, states[0] = -81.382988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312298627, states[0] = -87.817626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325176473, states[0] = 4.419059, states[40]= 0.006802
Saving checkpoint... 
Iteration: 337571520, states[0] = -82.447743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345753145, states[0] = -87.614834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354957175, states[0] = -87.806715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365666876, states[0] = 8.618648, states[40]= 0.007375
Saving checkpoint... 
Iteration: 376959907, states[0] = -87.820411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387119394, states[0] = -87.803054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398555856, states[0] = -66.828217, states[40]= 0.000003
Saving checkpoint... 
Iteration: 409184199, states[0] = -13.373896, states[40]= 0.002406
Saving checkpoint... 
Iteration: 420483119, states[0] = 15.849065, states[40]= 0.008987
Saving checkpoint... 
Iteration: 432950600, states[0] = -87.810067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445516702, states[0] = -17.348301, states[40]= 0.001629
Saving checkpoint... 
Iteration: 457682712, states[0] = -18.147050, states[40]= 0.001508
Saving checkpoint... 
Iteration: 469006530, states[0] = -6.674075, states[40]= 0.004266
Saving checkpoint... 
Iteration: 481235849, states[0] = -87.490716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493169330, states[0] = -4.927096, states[40]= 0.004780
Saving checkpoint... 
Iteration: 505263609, states[0] = -87.769218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516894281, states[0] = -86.964802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528101917, states[0] = -87.792712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540026825, states[0] = -44.701520, states[40]= 0.000083
Saving checkpoint... 
Iteration: 552121067, states[0] = 22.714427, states[40]= 0.050911
Saving checkpoint... 
Iteration: 564619446, states[0] = 22.908345, states[40]= 0.055023
Saving checkpoint... 
Iteration: 576862803, states[0] = -53.684190, states[40]= 0.000022
Saving checkpoint... 
Iteration: 590475280, states[0] = 10.301061, states[40]= 0.007611
Saving checkpoint... 
Iteration: 604019577, states[0] = -43.515019, states[40]= 0.000099
Saving checkpoint... 
Iteration: 617905025, states[0] = -87.715692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631516988, states[0] = -43.738900, states[40]= 0.000095
Saving checkpoint... 
Iteration: 644974888, states[0] = 6.713373, states[40]= 0.007122
Saving checkpoint... 
Iteration: 658341023, states[0] = -34.601260, states[40]= 0.000316
Saving checkpoint... 
Iteration: 671996342, states[0] = -20.615611, states[40]= 0.001197
Saving checkpoint... 
Iteration: 685399057, states[0] = -87.719005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698697279, states[0] = -75.080018, states[40]= 0.000001
Saving checkpoint... 
Iteration: 711922680, states[0] = -87.809668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725243867, states[0] = -87.776518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738308503, states[0] = -1.657836, states[40]= 0.005651
Saving checkpoint... 
Iteration: 751800166, states[0] = 4.668994, states[40]= 0.006839
Saving checkpoint... 
Iteration: 765158050, states[0] = -26.776016, states[40]= 0.000701
Saving checkpoint... 
Iteration: 778705413, states[0] = -87.450143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792282017, states[0] = 14.306510, states[40]= 0.008410
Saving checkpoint... 
Iteration: 805739782, states[0] = -87.789125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819228542, states[0] = -87.755966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832292239, states[0] = 4.569825, states[40]= 0.006824
Saving checkpoint... 
Iteration: 845685867, states[0] = -80.442646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859140250, states[0] = -14.855384, states[40]= 0.002081
Saving checkpoint... 
Iteration: 872567231, states[0] = -87.791516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886035449, states[0] = -87.656736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899548472, states[0] = -87.735719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912797932, states[0] = -9.842018, states[40]= 0.003330
Saving checkpoint... 
Iteration: 926328105, states[0] = -54.044397, states[40]= 0.000021
Saving checkpoint... 
Iteration: 939542576, states[0] = -87.728090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953014828, states[0] = -86.211450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966141885, states[0] = -32.262923, states[40]= 0.000411
Saving checkpoint... 
Iteration: 979504393, states[0] = -78.238818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992907254, states[0] = 25.026061, states[40]= 0.094489
Saving checkpoint... 
Iteration: 1005873287, states[0] = -87.743720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018584368, states[0] = 18.633471, states[40]= 0.011706
Saving checkpoint... 
Iteration: 1027334160, states[0] = -80.137947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037365385, states[0] = -87.724916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048585647, states[0] = 16.551297, states[40]= 0.009377
Saving checkpoint... 
Iteration: 1060278627, states[0] = -4.174468, states[40]= 0.004994
Saving checkpoint... 
Iteration: 1071789555, states[0] = -20.415796, states[40]= 0.001219
Saving checkpoint... 
Iteration: 1083418316, states[0] = 15.022824, states[40]= 0.008642
Saving checkpoint... 
Iteration: 1093365784, states[0] = -87.748408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102519122, states[0] = -87.695249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114307676, states[0] = -51.695914, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1126114162, states[0] = -15.727826, states[40]= 0.001910
Saving checkpoint... 
Iteration: 1137939632, states[0] = -6.675098, states[40]= 0.004266
Saving checkpoint... 
Iteration: 1149138053, states[0] = -52.455981, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1159030522, states[0] = -87.764893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170714937, states[0] = -87.822324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182839178, states[0] = -87.657253, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_148.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_148_1_r606720564_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_148_1_r606720564_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.043122
     * GNaL_b in INaL: 0.005785
     * Gto_b in Ito: 0.085377
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031903
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.163721
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.397886
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033774
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1182839178
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.657253 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1192743355, states[0] = 13.486275, states[40]= 0.008194
Saving checkpoint... 
Iteration: 1206025986, states[0] = -87.765382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214353816, states[0] = -87.748687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226025085, states[0] = -87.769117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240096911, states[0] = -7.720854, states[40]= 0.003953
Saving checkpoint... 
Iteration: 1254309786, states[0] = -77.488135, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268268092, states[0] = -17.834455, states[40]= 0.001554
Saving checkpoint... 
Iteration: 1282629374, states[0] = -59.329612, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1296729864, states[0] = 15.275284, states[40]= 0.008738
Saving checkpoint... 
Iteration: 1310326510, states[0] = -87.657902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324275297, states[0] = -35.805769, states[40]= 0.000274
Saving checkpoint... 
Iteration: 1338582442, states[0] = -2.325516, states[40]= 0.005486
Saving checkpoint... 
Iteration: 1352514797, states[0] = -87.776841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366190463, states[0] = -87.808522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380263259, states[0] = -26.859211, states[40]= 0.000695
Saving checkpoint... 
Iteration: 1394306098, states[0] = -86.868087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404970919, states[0] = -86.663858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416916853, states[0] = -13.518420, states[40]= 0.002372
Saving checkpoint... 
Iteration: 1428025543, states[0] = 40.635100, states[40]= 0.067844
Saving checkpoint... 
Iteration: 1441607690, states[0] = -50.856041, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1454271391, states[0] = -48.442140, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1466182805, states[0] = -87.814859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477146731, states[0] = -87.685402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490432671, states[0] = -45.950166, states[40]= 0.000070
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.700873
 - CaMKt in component CaMK (millimolar): 0.042252
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.005857
 - nass in component intracellular_ions (millimolar): 7.006005
 - ki in component intracellular_ions (millimolar): 144.914884
 - kss in component intracellular_ions (millimolar): 144.914852
 - cansr in component intracellular_ions (millimolar): 1.618096
 - cajsr in component intracellular_ions (millimolar): 1.186791
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007476
 - hf in component INa (dimensionless): 0.691952
 - hs in component INa (dimensionless): 0.691714
 - j in component INa (dimensionless): 0.681223
 - hsp in component INa (dimensionless): 0.446754
 - jp in component INa (dimensionless): 0.654787
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.293175
 - hLp in component INaL (dimensionless): 0.136269
 - a in component Ito (dimensionless): 0.001013
 - iF in component Ito (dimensionless): 0.999539
 - iS in component Ito (dimensionless): 0.175876
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999540
 - iSp in component Ito (dimensionless): 0.212860
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804463
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966926
 - jca in component ICaL (dimensionless): 0.948077
 - ffp in component ICaL (dimensionless): 0.999865
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009444
 - xrf in component IKr (dimensionless): 0.028545
 - xrs in component IKr (dimensionless): 0.787353
 - xs1 in component IKs (dimensionless): 0.458539
 - xs2 in component IKs (dimensionless): 0.001180
 - xk1 in component IK1 (dimensionless): 0.996811
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:55:46 (47744): called boinc_finish(0)

</stderr_txt>
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