𝕏

Task 56242871

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_1000-conf_146_0
Workunit 26712943
Created 4 Jul 2024, 22:20:35 UTC
Sent 5 Jul 2024, 13:34:17 UTC
Report deadline 8 Jul 2024, 13:34:17 UTC
Received 5 Jul 2024, 23:29:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226845
Run time 2 hours 26 min 10 sec
CPU time 2 hours 12 min 53 sec
Validate state Valid
Credit 43.78
Device peak FLOPS 3.27 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.69 MB
Peak swap size 4.10 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_1000-conf_146.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_1000-conf_146_0_r1123684913_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_1000-conf_146_0_r1123684913_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.834703
     * GNaL_b in INaL: 0.005831
     * Gto_b in Ito: 0.084373
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031958
     * GKs_b in IKs: 0.001936
     * GK1_b in IK1: 0.162678
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.528128
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033155
     * celltype in environment: 0.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9073980, states[0] = 12.035029, states[40]= 0.003400
Saving checkpoint... 
Iteration: 17398483, states[0] = -94.361123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25274621, states[0] = -94.153201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33856094, states[0] = -94.311451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42128259, states[0] = -29.543643, states[40]= 0.001523
Saving checkpoint... 
Iteration: 50200469, states[0] = -93.768614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58104589, states[0] = -7.550797, states[40]= 0.002775
Saving checkpoint... 
Iteration: 66372765, states[0] = -94.343717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74430908, states[0] = -94.389544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83183300, states[0] = -89.352997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91921571, states[0] = -94.387571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99210782, states[0] = -93.890001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107604094, states[0] = -7.502296, states[40]= 0.002729
Saving checkpoint... 
Iteration: 116344199, states[0] = -94.317601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124729081, states[0] = -93.991968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133134597, states[0] = -36.277755, states[40]= 0.000932
Saving checkpoint... 
Iteration: 141235657, states[0] = -94.024171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149128958, states[0] = -31.143829, states[40]= 0.001368
Saving checkpoint... 
Iteration: 157602076, states[0] = -5.806027, states[40]= 0.002936
Saving checkpoint... 
Iteration: 165700250, states[0] = -93.793628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173925029, states[0] = -94.393154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182321748, states[0] = -94.283536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189906719, states[0] = -94.381545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198534743, states[0] = 27.966071, states[40]= 0.000134
Saving checkpoint... 
Iteration: 206121283, states[0] = -24.134491, states[40]= 0.001481
Saving checkpoint... 
Iteration: 214295995, states[0] = -94.230238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222696809, states[0] = -93.707428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230743889, states[0] = -94.061005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238702539, states[0] = -93.826003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246607672, states[0] = -10.969282, states[40]= 0.002182
Saving checkpoint... 
Iteration: 254524072, states[0] = 31.256653, states[40]= 0.000517
Saving checkpoint... 
Iteration: 262872136, states[0] = -94.351628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271000578, states[0] = 30.786771, states[40]= 0.016251
Saving checkpoint... 
Iteration: 279135893, states[0] = -37.531861, states[40]= 0.000823
Saving checkpoint... 
Iteration: 286891430, states[0] = -94.369133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294136709, states[0] = -38.285785, states[40]= 0.000761
Saving checkpoint... 
Iteration: 302394890, states[0] = -94.371783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310932075, states[0] = -94.395982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319021336, states[0] = 31.850794, states[40]= 0.001235
Saving checkpoint... 
Iteration: 327265226, states[0] = -94.141483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335377503, states[0] = -94.356223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344038972, states[0] = 26.404582, states[40]= 0.000167
Saving checkpoint... 
Iteration: 351639527, states[0] = -40.906779, states[40]= 0.000570
Saving checkpoint... 
Iteration: 359421376, states[0] = -94.389492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367576980, states[0] = 9.876446, states[40]= 0.001721
Saving checkpoint... 
Iteration: 375800305, states[0] = -94.238687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383900802, states[0] = -94.375512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392207752, states[0] = -93.870771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400180119, states[0] = -86.171351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 408147820, states[0] = -48.804732, states[40]= 0.000210
Saving checkpoint... 
Iteration: 416860725, states[0] = -94.337684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424375200, states[0] = -94.353075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431566223, states[0] = 14.948184, states[40]= 0.000966
Saving checkpoint... 
Iteration: 440112519, states[0] = -15.731622, states[40]= 0.001571
Saving checkpoint... 
Iteration: 448277703, states[0] = -94.179542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456305345, states[0] = -94.248961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464519740, states[0] = 32.123513, states[40]= 0.002109
Saving checkpoint... 
Iteration: 472252511, states[0] = -94.093798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480756230, states[0] = -94.107908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488980828, states[0] = -94.413951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497292356, states[0] = -94.218592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505739472, states[0] = -94.038863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513602675, states[0] = -6.341718, states[40]= 0.002870
Saving checkpoint... 
Iteration: 521355189, states[0] = -94.330023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529266391, states[0] = -94.143313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537239270, states[0] = -94.037630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546003612, states[0] = 37.529201, states[40]= 0.555572
Saving checkpoint... 
Iteration: 554276873, states[0] = -94.176006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562185752, states[0] = -91.525017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570249500, states[0] = -94.080854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578547108, states[0] = 23.185988, states[40]= 0.000287
Saving checkpoint... 
Iteration: 586860552, states[0] = -94.335750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593930882, states[0] = -94.392474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602364539, states[0] = -94.340108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610298388, states[0] = -94.231891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618666564, states[0] = -67.730937, states[40]= 0.000012
Saving checkpoint... 
Iteration: 626687793, states[0] = -92.448013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634943046, states[0] = -94.398145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642900835, states[0] = -94.372900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650530728, states[0] = 29.339312, states[40]= 0.000139
Saving checkpoint... 
Iteration: 657898412, states[0] = -94.370917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665859005, states[0] = -94.333137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674073681, states[0] = 11.479645, states[40]= 0.001458
Saving checkpoint... 
Iteration: 682545175, states[0] = 23.971121, states[40]= 0.000252
Saving checkpoint... 
Iteration: 691258289, states[0] = -94.113345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699546771, states[0] = 23.323951, states[40]= 0.000280
Saving checkpoint... 
Iteration: 707958405, states[0] = -94.403988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716403555, states[0] = -94.374149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724591973, states[0] = 1.628922, states[40]= 0.003000
Saving checkpoint... 
Iteration: 732756810, states[0] = -94.107466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740492038, states[0] = -94.414553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748491843, states[0] = -94.414420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756033171, states[0] = 28.518753, states[40]= 0.000130
Saving checkpoint... 
Iteration: 762956066, states[0] = -94.402499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770772190, states[0] = -94.159540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778616825, states[0] = -19.928284, states[40]= 0.001379
Saving checkpoint... 
Iteration: 787171333, states[0] = -73.573117, states[40]= 0.000005
Saving checkpoint... 
Iteration: 795429211, states[0] = -94.389521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803812269, states[0] = -94.259653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811941675, states[0] = -94.395700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819301295, states[0] = -94.236369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827264218, states[0] = -94.132902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835173544, states[0] = -76.603727, states[40]= 0.000003
Saving checkpoint... 
Iteration: 843654966, states[0] = -55.739250, states[40]= 0.000077
Saving checkpoint... 
Iteration: 852220478, states[0] = -93.941600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860423920, states[0] = -94.385888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868940654, states[0] = -94.394633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876823481, states[0] = -94.279756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885650627, states[0] = -51.514573, states[40]= 0.000144
Saving checkpoint... 
Iteration: 893482748, states[0] = -94.410413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901578152, states[0] = 9.297354, states[40]= 0.001820
Saving checkpoint... 
Iteration: 909956934, states[0] = -94.401353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918222325, states[0] = -93.950777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926494153, states[0] = -94.413212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935020841, states[0] = 31.943722, states[40]= 0.001455
Saving checkpoint... 
Iteration: 942872974, states[0] = -94.345566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950894836, states[0] = -94.365141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959356263, states[0] = -94.326864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967617352, states[0] = -20.431103, states[40]= 0.001381
Saving checkpoint... 
Iteration: 974898682, states[0] = -94.367895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983720086, states[0] = -93.938114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991781769, states[0] = -94.185599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000005250, states[0] = 33.180937, states[40]= 0.318243
Saving checkpoint... 
Iteration: 1008146421, states[0] = -47.447015, states[40]= 0.000252
Saving checkpoint... 
Iteration: 1015994552, states[0] = -94.412404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024058857, states[0] = 18.222961, states[40]= 0.000619
Saving checkpoint... 
Iteration: 1032271621, states[0] = -94.155063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040544024, states[0] = 24.434297, states[40]= 0.000233
Saving checkpoint... 
Iteration: 1047196237, states[0] = -93.676002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055292902, states[0] = -94.214212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063832481, states[0] = -94.292789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071821236, states[0] = -94.273793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080171076, states[0] = -73.225237, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1088373750, states[0] = -94.344864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096903789, states[0] = -94.370444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105171672, states[0] = -74.013523, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1112920598, states[0] = -94.381361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120614524, states[0] = -17.693745, states[40]= 0.001434
Saving checkpoint... 
Iteration: 1128769477, states[0] = -94.147247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136925168, states[0] = -94.383792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145602601, states[0] = -6.270735, states[40]= 0.002879
Saving checkpoint... 
Iteration: 1153460710, states[0] = -94.400352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161975263, states[0] = -94.405379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170108918, states[0] = -12.172994, states[40]= 0.002001
Saving checkpoint... 
Iteration: 1177356162, states[0] = -94.324516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185419222, states[0] = -94.379792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193754014, states[0] = -94.092149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201732243, states[0] = -93.997999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208605575, states[0] = -8.962048, states[40]= 0.002497
Saving checkpoint... 
Iteration: 1216333567, states[0] = -94.292934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224833803, states[0] = -94.293215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232815433, states[0] = -94.261412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240613696, states[0] = -16.880951, states[40]= 0.001481
Saving checkpoint... 
Iteration: 1248654792, states[0] = -55.562123, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1257085252, states[0] = 5.586917, states[40]= 0.002459
Saving checkpoint... 
Iteration: 1265264949, states[0] = -94.130873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274002694, states[0] = 42.091062, states[40]= 0.737079
Saving checkpoint... 
Iteration: 1282620390, states[0] = -23.296380, states[40]= 0.001452
Saving checkpoint... 
Iteration: 1290415841, states[0] = -94.376624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299033924, states[0] = 28.258052, states[40]= 0.000131
Saving checkpoint... 
Iteration: 1306900429, states[0] = -94.365835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315066160, states[0] = 14.980375, states[40]= 0.000963
Saving checkpoint... 
Iteration: 1323073076, states[0] = 11.771252, states[40]= 0.001413
Saving checkpoint... 
Iteration: 1330598611, states[0] = -2.993392, states[40]= 0.003152
Saving checkpoint... 
Iteration: 1338219390, states[0] = -93.930645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346728975, states[0] = -93.980473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354834944, states[0] = -94.293650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363377058, states[0] = -94.345317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371610859, states[0] = -14.080953, states[40]= 0.001745
Saving checkpoint... 
Iteration: 1380492896, states[0] = -94.408275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388148455, states[0] = -49.403365, states[40]= 0.000194
Saving checkpoint... 
Iteration: 1396274250, states[0] = -94.159455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404397503, states[0] = -94.362615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412342196, states[0] = -94.303768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420060083, states[0] = 17.688800, states[40]= 0.000668
Saving checkpoint... 
Iteration: 1429254692, states[0] = -94.092305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437707725, states[0] = -93.859609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446183629, states[0] = -90.000581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454805642, states[0] = -94.239358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463234681, states[0] = -94.006907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471029421, states[0] = 29.759376, states[40]= 0.000157
Saving checkpoint... 
Iteration: 1478699880, states[0] = -93.773515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486647677, states[0] = -48.650382, states[40]= 0.000215
Saving checkpoint... 
Iteration: 1494920281, states[0] = -94.377284, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.284705
 - CaMKt in component CaMK (millimolar): 0.017757
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.025728
 - nass in component intracellular_ions (millimolar): 7.025852
 - ki in component intracellular_ions (millimolar): 144.752639
 - kss in component intracellular_ions (millimolar): 144.752619
 - cansr in component intracellular_ions (millimolar): 1.943295
 - cajsr in component intracellular_ions (millimolar): 1.898952
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003851
 - hf in component INa (dimensionless): 0.868873
 - hs in component INa (dimensionless): 0.868863
 - j in component INa (dimensionless): 0.868795
 - hsp in component INa (dimensionless): 0.705164
 - jp in component INa (dimensionless): 0.868746
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.687209
 - hLp in component INaL (dimensionless): 0.417460
 - a in component Ito (dimensionless): 0.000650
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.596145
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.662323
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.899987
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999757
 - jca in component ICaL (dimensionless): 0.999965
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004603
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.398166
 - xs1 in component IKs (dimensionless): 0.291754
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997495
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:29:04 (29348): called boinc_finish(0)

</stderr_txt>
]]>


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