𝕏

Task 56234847

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_500-conf_438_1
Workunit 26708947
Created 4 Jul 2024, 21:47:25 UTC
Sent 5 Jul 2024, 12:40:46 UTC
Report deadline 8 Jul 2024, 12:40:46 UTC
Received 6 Jul 2024, 14:51:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236258
Run time 46 min 12 sec
CPU time 37 min 45 sec
Validate state Valid
Credit 44.47
Device peak FLOPS 9.52 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.69 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_500-conf_438.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_500-conf_438_1_r2111036388_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_500-conf_438_1_r2111036388_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.790247
     * GNaL_b in INaL: 0.005880
     * Gto_b in Ito: 0.084341
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031780
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.163348
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.549559
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032602
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10740775, states[0] = -87.480433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21186446, states[0] = -87.362416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30676589, states[0] = -87.324534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42320059, states[0] = -12.136539, states[40]= 0.002280
Saving checkpoint... 
Iteration: 53496572, states[0] = -87.430095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63860823, states[0] = -62.501883, states[40]= 0.000004
Saving checkpoint... 
Iteration: 73890320, states[0] = -87.143025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85898878, states[0] = -87.217824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96526795, states[0] = 18.288459, states[40]= 0.007354
Saving checkpoint... 
Iteration: 106267737, states[0] = 21.648320, states[40]= 0.012330
Saving checkpoint... 
Iteration: 119186011, states[0] = -87.320303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127805385, states[0] = 2.085136, states[40]= 0.005257
Saving checkpoint... 
Iteration: 140133243, states[0] = -86.701314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151109131, states[0] = -59.723962, states[40]= 0.000006
Saving checkpoint... 
Iteration: 163200585, states[0] = -87.349706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174247187, states[0] = -87.419214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183433983, states[0] = -87.314476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197133340, states[0] = -86.711072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203166212, states[0] = -87.269393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211249748, states[0] = -87.421893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224439515, states[0] = -87.326722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236115973, states[0] = -69.713742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 247766152, states[0] = 22.110715, states[40]= 0.014943
Saving checkpoint... 
Iteration: 259770000, states[0] = 20.945519, states[40]= 0.010046
Saving checkpoint... 
Iteration: 271771215, states[0] = 20.525602, states[40]= 0.009246
Saving checkpoint... 
Iteration: 284425085, states[0] = -87.292704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297272302, states[0] = 20.129858, states[40]= 0.008695
Saving checkpoint... 
Iteration: 306618752, states[0] = -74.137966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 319766326, states[0] = 22.063545, states[40]= 0.014601
Saving checkpoint... 
Iteration: 332339063, states[0] = -34.500054, states[40]= 0.000269
Saving checkpoint... 
Iteration: 344237590, states[0] = -87.407358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355484678, states[0] = -87.403608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365165158, states[0] = -87.266224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374651108, states[0] = -87.222600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385989394, states[0] = -87.409570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394141563, states[0] = -87.154774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405703317, states[0] = -87.354342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419229645, states[0] = -87.396781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427938945, states[0] = -87.325231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434787263, states[0] = 13.196861, states[40]= 0.006238
Saving checkpoint... 
Iteration: 445299295, states[0] = 6.204140, states[40]= 0.005655
Saving checkpoint... 
Iteration: 456254955, states[0] = 27.631034, states[40]= 0.127403
Saving checkpoint... 
Iteration: 464611024, states[0] = -62.332344, states[40]= 0.000004
Saving checkpoint... 
Iteration: 476297876, states[0] = 7.093429, states[40]= 0.005724
Saving checkpoint... 
Iteration: 486393106, states[0] = -87.174363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497513922, states[0] = 22.678223, states[40]= 0.021075
Saving checkpoint... 
Iteration: 511200444, states[0] = -87.348785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521331958, states[0] = -25.945158, states[40]= 0.000650
Saving checkpoint... 
Iteration: 533654860, states[0] = -87.235454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544165321, states[0] = -87.266493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551665086, states[0] = -87.265830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560067150, states[0] = -8.279197, states[40]= 0.003178
Saving checkpoint... 
Iteration: 571789219, states[0] = 12.137215, states[40]= 0.006127
Saving checkpoint... 
Iteration: 580456296, states[0] = -87.359628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594086710, states[0] = -31.675867, states[40]= 0.000374
Saving checkpoint... 
Iteration: 604975875, states[0] = -87.391265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614762108, states[0] = 23.108395, states[40]= 0.029624
Saving checkpoint... 
Iteration: 625530446, states[0] = 16.649942, states[40]= 0.006808
Saving checkpoint... 
Iteration: 637093245, states[0] = -39.528199, states[40]= 0.000139
Saving checkpoint... 
Iteration: 649981546, states[0] = -87.399143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661650294, states[0] = -87.219143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671270677, states[0] = 20.714728, states[40]= 0.009573
Saving checkpoint... 
Iteration: 680215210, states[0] = -87.374819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690391734, states[0] = -87.156992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702009072, states[0] = 23.967216, states[40]= 0.056946
Saving checkpoint... 
Iteration: 714817455, states[0] = -8.610138, states[40]= 0.003096
Saving checkpoint... 
Iteration: 727383296, states[0] = -86.703643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735796752, states[0] = 7.783886, states[40]= 0.005776
Saving checkpoint... 
Iteration: 747661179, states[0] = -87.254498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759403730, states[0] = -87.231495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767975128, states[0] = -87.390015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781200463, states[0] = -87.348543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790786098, states[0] = 13.814718, states[40]= 0.006312
Saving checkpoint... 
Iteration: 803739134, states[0] = -87.408819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814845764, states[0] = -42.588480, states[40]= 0.000090
Saving checkpoint... 
Iteration: 824624567, states[0] = -82.340160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837052763, states[0] = 3.933827, states[40]= 0.005457
Saving checkpoint... 
Iteration: 844803217, states[0] = 3.624723, states[40]= 0.005426
Saving checkpoint... 
Iteration: 857125510, states[0] = -83.274852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869723223, states[0] = -87.387107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883386506, states[0] = -86.997788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894007619, states[0] = 24.657176, states[40]= 0.078533
Saving checkpoint... 
Iteration: 906624164, states[0] = -81.897374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912529728, states[0] = 16.988509, states[40]= 0.006895
Saving checkpoint... 
Iteration: 925022654, states[0] = 19.998022, states[40]= 0.008543
Saving checkpoint... 
Iteration: 936850797, states[0] = -48.831516, states[40]= 0.000035
Saving checkpoint... 
Iteration: 948394095, states[0] = -87.183480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958014151, states[0] = 22.622880, states[40]= 0.020263
Saving checkpoint... 
Iteration: 967976629, states[0] = -87.391975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978383215, states[0] = -86.691914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988010530, states[0] = 23.505701, states[40]= 0.041245
Saving checkpoint... 
Iteration: 998110287, states[0] = -61.295582, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1009345217, states[0] = -41.920478, states[40]= 0.000099
Saving checkpoint... 
Iteration: 1019614392, states[0] = -67.267890, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1028852690, states[0] = -51.230746, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1039334103, states[0] = -28.537312, states[40]= 0.000515
Saving checkpoint... 
Iteration: 1052305288, states[0] = 2.172786, states[40]= 0.005267
Saving checkpoint... 
Iteration: 1062126147, states[0] = -83.825587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074303358, states[0] = 3.528236, states[40]= 0.005417
Saving checkpoint... 
Iteration: 1084975562, states[0] = -87.390319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092713671, states[0] = -87.371864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100834659, states[0] = -29.207602, states[40]= 0.000483
Saving checkpoint... 
Iteration: 1110983210, states[0] = -87.400900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123205115, states[0] = -87.356924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134023593, states[0] = 19.636714, states[40]= 0.008187
Saving checkpoint... 
Iteration: 1142399713, states[0] = -87.216277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154624248, states[0] = -81.990892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164822548, states[0] = -14.496620, states[40]= 0.001814
Saving checkpoint... 
Iteration: 1174640292, states[0] = -87.131423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183294568, states[0] = 9.093031, states[40]= 0.005873
Saving checkpoint... 
Iteration: 1194107694, states[0] = -57.754235, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1204673655, states[0] = -87.288103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211811145, states[0] = -2.433840, states[40]= 0.004537
Saving checkpoint... 
Iteration: 1218786188, states[0] = 13.767552, states[40]= 0.006306
Saving checkpoint... 
Iteration: 1231561979, states[0] = -3.168722, states[40]= 0.004386
Saving checkpoint... 
Iteration: 1244192163, states[0] = -87.331310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253984661, states[0] = -87.402663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264296975, states[0] = 7.648153, states[40]= 0.005765
Saving checkpoint... 
Iteration: 1274233476, states[0] = -87.401085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287394947, states[0] = -87.190055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297926557, states[0] = -87.295350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310673368, states[0] = -87.287255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321120995, states[0] = -77.646810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334861367, states[0] = -62.817097, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1348557517, states[0] = 0.519581, states[40]= 0.005047
Saving checkpoint... 
Iteration: 1359871763, states[0] = -78.781038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370622158, states[0] = -79.342743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383275658, states[0] = 18.798247, states[40]= 0.007600
Saving checkpoint... 
Iteration: 1394919678, states[0] = -87.277493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408735636, states[0] = -87.403771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422364426, states[0] = -67.318396, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1436216832, states[0] = -87.376662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446811046, states[0] = -2.347921, states[40]= 0.004554
Saving checkpoint... 
Iteration: 1457579350, states[0] = -22.776568, states[40]= 0.000846
Saving checkpoint... 
Iteration: 1469719195, states[0] = -87.380358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478887976, states[0] = -87.065595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489063826, states[0] = -4.881902, states[40]= 0.004006
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.296544
 - CaMKt in component CaMK (millimolar): 0.019437
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.739429
 - nass in component intracellular_ions (millimolar): 6.739529
 - ki in component intracellular_ions (millimolar): 145.217804
 - kss in component intracellular_ions (millimolar): 145.217777
 - cansr in component intracellular_ions (millimolar): 1.425494
 - cajsr in component intracellular_ions (millimolar): 1.207758
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.007786
 - hf in component INa (dimensionless): 0.677610
 - hs in component INa (dimensionless): 0.677508
 - j in component INa (dimensionless): 0.676809
 - hsp in component INa (dimensionless): 0.431085
 - jp in component INa (dimensionless): 0.674847
 - mL in component INaL (dimensionless): 0.000210
 - hL in component INaL (dimensionless): 0.386464
 - hLp in component INaL (dimensionless): 0.180933
 - a in component Ito (dimensionless): 0.001041
 - iF in component Ito (dimensionless): 0.999506
 - iS in component Ito (dimensionless): 0.292737
 - ap in component Ito (dimensionless): 0.000530
 - iFp in component Ito (dimensionless): 0.999506
 - iSp in component Ito (dimensionless): 0.340157
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.856961
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990985
 - jca in component ICaL (dimensionless): 0.991333
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004197
 - xrf in component IKr (dimensionless): 0.001774
 - xrs in component IKr (dimensionless): 0.673980
 - xs1 in component IKs (dimensionless): 0.384303
 - xs2 in component IKs (dimensionless): 0.000215
 - xk1 in component IK1 (dimensionless): 0.996911
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:04:27 (1700415): called boinc_finish(0)

</stderr_txt>
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