𝕏

Task 56234843

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_500-conf_338_1
Workunit 26708945
Created 4 Jul 2024, 21:47:25 UTC
Sent 5 Jul 2024, 12:40:46 UTC
Report deadline 8 Jul 2024, 12:40:46 UTC
Received 6 Jul 2024, 12:37:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236258
Run time 45 min 13 sec
CPU time 37 min 25 sec
Validate state Valid
Credit 43.63
Device peak FLOPS 9.52 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.69 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_500-conf_338.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_500-conf_338_1_r1762440578_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_500-conf_338_1_r1762440578_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.944996
     * GNaL_b in INaL: 0.005801
     * Gto_b in Ito: 0.083622
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031828
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.164600
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.390566
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032619
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12834902, states[0] = -31.948038, states[40]= 0.000340
Saving checkpoint... 
Iteration: 21080073, states[0] = -25.426690, states[40]= 0.000667
Saving checkpoint... 
Iteration: 34295044, states[0] = 8.415762, states[40]= 0.005850
Saving checkpoint... 
Iteration: 39294375, states[0] = 8.868981, states[40]= 0.005885
Saving checkpoint... 
Iteration: 50285535, states[0] = 13.909461, states[40]= 0.006372
Saving checkpoint... 
Iteration: 61336962, states[0] = -32.692102, states[40]= 0.000332
Saving checkpoint... 
Iteration: 74674950, states[0] = -87.315770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86776087, states[0] = 18.551701, states[40]= 0.007548
Saving checkpoint... 
Iteration: 99316117, states[0] = -7.478129, states[40]= 0.003378
Saving checkpoint... 
Iteration: 111415057, states[0] = -87.285665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123429968, states[0] = -87.323379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132049666, states[0] = 5.851448, states[40]= 0.005637
Saving checkpoint... 
Iteration: 143730888, states[0] = -87.415449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154473678, states[0] = -87.405163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167725200, states[0] = -87.407213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179737204, states[0] = -87.423217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193068669, states[0] = -10.208156, states[40]= 0.002711
Saving checkpoint... 
Iteration: 201241865, states[0] = -87.428792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211784228, states[0] = 14.727250, states[40]= 0.006474
Saving checkpoint... 
Iteration: 225273042, states[0] = 19.828078, states[40]= 0.008450
Saving checkpoint... 
Iteration: 236317346, states[0] = -8.726707, states[40]= 0.003069
Saving checkpoint... 
Iteration: 247523459, states[0] = 19.665466, states[40]= 0.008294
Saving checkpoint... 
Iteration: 256041855, states[0] = 10.586177, states[40]= 0.006009
Saving checkpoint... 
Iteration: 267401329, states[0] = -87.242181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277098766, states[0] = -46.717075, states[40]= 0.000048
Saving checkpoint... 
Iteration: 288314560, states[0] = -5.803188, states[40]= 0.003788
Saving checkpoint... 
Iteration: 297708655, states[0] = -87.380702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307327407, states[0] = -20.712768, states[40]= 0.001008
Saving checkpoint... 
Iteration: 318766385, states[0] = 22.054724, states[40]= 0.014587
Saving checkpoint... 
Iteration: 332288843, states[0] = 12.274069, states[40]= 0.006166
Saving checkpoint... 
Iteration: 344585817, states[0] = -30.943957, states[40]= 0.000403
Saving checkpoint... 
Iteration: 357652263, states[0] = -87.245355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366248115, states[0] = -87.435709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377806653, states[0] = 1.034498, states[40]= 0.005123
Saving checkpoint... 
Iteration: 387740497, states[0] = -87.426887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396992491, states[0] = -87.429255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408785108, states[0] = 14.272804, states[40]= 0.006407
Saving checkpoint... 
Iteration: 421338368, states[0] = -34.019974, states[40]= 0.000284
Saving checkpoint... 
Iteration: 432345274, states[0] = -42.388802, states[40]= 0.000092
Saving checkpoint... 
Iteration: 445056198, states[0] = 1.374848, states[40]= 0.005170
Saving checkpoint... 
Iteration: 456536110, states[0] = 13.746952, states[40]= 0.006335
Saving checkpoint... 
Iteration: 466880576, states[0] = -86.315196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479929046, states[0] = -87.319706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492822698, states[0] = -14.957210, states[40]= 0.001735
Saving checkpoint... 
Iteration: 506324125, states[0] = -16.692877, states[40]= 0.001464
Saving checkpoint... 
Iteration: 516251630, states[0] = 40.789100, states[40]= 0.071483
Saving checkpoint... 
Iteration: 529385320, states[0] = -86.980003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538625795, states[0] = -83.989198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550571580, states[0] = -13.610653, states[40]= 0.001978
Saving checkpoint... 
Iteration: 562994909, states[0] = -87.431900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575141061, states[0] = -87.173350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586464142, states[0] = -87.389626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597914770, states[0] = -87.282726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608411880, states[0] = -87.274600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620074188, states[0] = -16.769652, states[40]= 0.001453
Saving checkpoint... 
Iteration: 632641954, states[0] = -87.185096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646857654, states[0] = -58.226773, states[40]= 0.000008
Saving checkpoint... 
Iteration: 655421610, states[0] = -87.300980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667894091, states[0] = -87.205636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678735439, states[0] = -87.420317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691659587, states[0] = -87.267894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702273402, states[0] = 19.688165, states[40]= 0.008315
Saving checkpoint... 
Iteration: 711585649, states[0] = -30.740522, states[40]= 0.000412
Saving checkpoint... 
Iteration: 724170030, states[0] = -87.296788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734701284, states[0] = -87.366934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746843927, states[0] = -40.741206, states[40]= 0.000116
Saving checkpoint... 
Iteration: 758334043, states[0] = -28.798211, states[40]= 0.000501
Saving checkpoint... 
Iteration: 769197759, states[0] = -87.360125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780803193, states[0] = 3.522045, states[40]= 0.005422
Saving checkpoint... 
Iteration: 792583277, states[0] = -27.869877, states[40]= 0.000546
Saving checkpoint... 
Iteration: 802351507, states[0] = -50.179088, states[40]= 0.000028
Saving checkpoint... 
Iteration: 815398282, states[0] = -87.229607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821029849, states[0] = 16.888254, states[40]= 0.006918
Saving checkpoint... 
Iteration: 833026349, states[0] = 18.471914, states[40]= 0.007496
Saving checkpoint... 
Iteration: 844607797, states[0] = -58.420207, states[40]= 0.000008
Saving checkpoint... 
Iteration: 854414150, states[0] = -87.280745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862474001, states[0] = -87.404530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873855919, states[0] = -55.903466, states[40]= 0.000011
Saving checkpoint... 
Iteration: 883914761, states[0] = -87.282411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892384804, states[0] = -86.942428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903753771, states[0] = 30.759157, states[40]= 0.134934
Saving checkpoint... 
Iteration: 916723058, states[0] = -87.403096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927015812, states[0] = 22.212445, states[40]= 0.015759
Saving checkpoint... 
Iteration: 938303029, states[0] = 3.634875, states[40]= 0.005433
Saving checkpoint... 
Iteration: 947396746, states[0] = -87.222128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956886176, states[0] = -87.030378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969931071, states[0] = -87.324020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979753332, states[0] = 32.363190, states[40]= 0.131542
Saving checkpoint... 
Iteration: 991072849, states[0] = -15.139472, states[40]= 0.001704
Saving checkpoint... 
Iteration: 1001822440, states[0] = -14.644548, states[40]= 0.001789
Saving checkpoint... 
Iteration: 1013434631, states[0] = -87.332189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021995376, states[0] = -87.431972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034610130, states[0] = -61.646370, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1041725967, states[0] = -87.407178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053958860, states[0] = -87.380291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064377091, states[0] = -84.891631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075528421, states[0] = 17.551240, states[40]= 0.007120
Saving checkpoint... 
Iteration: 1086256590, states[0] = 25.510790, states[40]= 0.096801
Saving checkpoint... 
Iteration: 1093498784, states[0] = -87.435715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103744442, states[0] = -87.430819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116888073, states[0] = -87.107860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131177616, states[0] = -87.315587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142981155, states[0] = -87.414243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156420339, states[0] = -87.297161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168264447, states[0] = 22.568859, states[40]= 0.019390
Saving checkpoint... 
Iteration: 1180799046, states[0] = 6.260510, states[40]= 0.005670
Saving checkpoint... 
Iteration: 1192738516, states[0] = -87.423661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200190981, states[0] = -87.345892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210645070, states[0] = -87.212073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224452080, states[0] = -87.367932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235438840, states[0] = -87.341279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244267087, states[0] = 21.854837, states[40]= 0.013371
Saving checkpoint... 
Iteration: 1253366883, states[0] = -71.881424, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1264319185, states[0] = -10.793379, states[40]= 0.002575
Saving checkpoint... 
Iteration: 1273229486, states[0] = -87.411852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284850927, states[0] = -49.440215, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1297363673, states[0] = -66.836417, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1309013423, states[0] = 22.822627, states[40]= 0.023133
Saving checkpoint... 
Iteration: 1319951199, states[0] = -87.366183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330535370, states[0] = 14.136463, states[40]= 0.006387
Saving checkpoint... 
Iteration: 1342003630, states[0] = 31.241064, states[40]= 0.134333
Saving checkpoint... 
Iteration: 1352972469, states[0] = -87.401787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365837040, states[0] = -32.418131, states[40]= 0.000343
Saving checkpoint... 
Iteration: 1377769479, states[0] = 21.110979, states[40]= 0.010546
Saving checkpoint... 
Iteration: 1390747774, states[0] = -87.434301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400064653, states[0] = -5.894964, states[40]= 0.003766
Saving checkpoint... 
Iteration: 1410179068, states[0] = -87.318816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421305821, states[0] = 1.654173, states[40]= 0.005206
Saving checkpoint... 
Iteration: 1433286783, states[0] = 13.389870, states[40]= 0.006290
Saving checkpoint... 
Iteration: 1444894522, states[0] = -87.208058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455980448, states[0] = -87.412976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465655624, states[0] = -87.255169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475602191, states[0] = -51.051991, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1487789481, states[0] = 11.922796, states[40]= 0.006131
Saving checkpoint... 
Iteration: 1496949187, states[0] = -87.362166, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.312385
 - CaMKt in component CaMK (millimolar): 0.019278
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 6.738533
 - nass in component intracellular_ions (millimolar): 6.738633
 - ki in component intracellular_ions (millimolar): 145.219450
 - kss in component intracellular_ions (millimolar): 145.219423
 - cansr in component intracellular_ions (millimolar): 1.422419
 - cajsr in component intracellular_ions (millimolar): 1.205635
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007774
 - hf in component INa (dimensionless): 0.678179
 - hs in component INa (dimensionless): 0.678078
 - j in component INa (dimensionless): 0.677390
 - hsp in component INa (dimensionless): 0.431728
 - jp in component INa (dimensionless): 0.675467
 - mL in component INaL (dimensionless): 0.000210
 - hL in component INaL (dimensionless): 0.387636
 - hLp in component INaL (dimensionless): 0.181791
 - a in component Ito (dimensionless): 0.001040
 - iF in component Ito (dimensionless): 0.999508
 - iS in component Ito (dimensionless): 0.293495
 - ap in component Ito (dimensionless): 0.000530
 - iFp in component Ito (dimensionless): 0.999508
 - iSp in component Ito (dimensionless): 0.341195
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.857486
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991039
 - jca in component ICaL (dimensionless): 0.991399
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004175
 - xrf in component IKr (dimensionless): 0.001736
 - xrs in component IKr (dimensionless): 0.673647
 - xs1 in component IKs (dimensionless): 0.383384
 - xs2 in component IKs (dimensionless): 0.000214
 - xk1 in component IK1 (dimensionless): 0.996907
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:41:07 (1584936): called boinc_finish(0)

</stderr_txt>
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