𝕏

Task 56234794

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_838_0
Workunit 26708921
Created 4 Jul 2024, 21:47:20 UTC
Sent 5 Jul 2024, 12:40:46 UTC
Report deadline 8 Jul 2024, 12:40:46 UTC
Received 6 Jul 2024, 13:47:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236258
Run time 45 min 25 sec
CPU time 37 min 21 sec
Validate state Valid
Credit 45.14
Device peak FLOPS 9.52 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.89 MB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_838.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_838_0_r995253189_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_838_0_r995253189_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.448124
     * GNaL_b in INaL: 0.005891
     * Gto_b in Ito: 0.085476
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031838
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.162667
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.362077
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033989
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12654421, states[0] = -86.053592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21909712, states[0] = -87.058602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33260563, states[0] = -86.929504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45161798, states[0] = -86.342355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57296776, states[0] = -86.927595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68236398, states[0] = -86.846313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77681461, states[0] = -86.732954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87343505, states[0] = -86.939090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100933638, states[0] = -86.967226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111331290, states[0] = -86.924751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122463197, states[0] = -86.968638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132984154, states[0] = -86.970550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143592683, states[0] = -13.541295, states[40]= 0.001643
Saving checkpoint... 
Iteration: 155967280, states[0] = -86.966104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167179164, states[0] = -86.707316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177342342, states[0] = -86.925055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186076472, states[0] = -0.557968, states[40]= 0.004059
Saving checkpoint... 
Iteration: 192627787, states[0] = -48.929153, states[40]= 0.000029
Saving checkpoint... 
Iteration: 204068887, states[0] = 3.625070, states[40]= 0.004478
Saving checkpoint... 
Iteration: 215559407, states[0] = 8.042546, states[40]= 0.004670
Saving checkpoint... 
Iteration: 225143909, states[0] = -67.871694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 233504072, states[0] = 28.489033, states[40]= 0.162637
Saving checkpoint... 
Iteration: 245863994, states[0] = -86.934878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256269686, states[0] = -86.865351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266917519, states[0] = -86.953538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276195637, states[0] = -86.745607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287927645, states[0] = -86.956076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300227905, states[0] = -86.806703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312325675, states[0] = -86.913930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324412327, states[0] = -86.952005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336425814, states[0] = -86.955559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348718927, states[0] = -86.790913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361193379, states[0] = -86.740822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371816182, states[0] = -86.907400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383578134, states[0] = -1.573963, states[40]= 0.003914
Saving checkpoint... 
Iteration: 394093211, states[0] = -13.938598, states[40]= 0.001581
Saving checkpoint... 
Iteration: 404261659, states[0] = -86.855645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415054359, states[0] = 10.190277, states[40]= 0.004703
Saving checkpoint... 
Iteration: 425213365, states[0] = -86.780553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436307903, states[0] = -86.901189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448406651, states[0] = -86.950258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456526163, states[0] = 20.468237, states[40]= 0.006009
Saving checkpoint... 
Iteration: 467824175, states[0] = -86.912814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480530580, states[0] = 19.156131, states[40]= 0.005398
Saving checkpoint... 
Iteration: 493665876, states[0] = -86.417744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501862518, states[0] = -86.933884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515083456, states[0] = -5.302190, states[40]= 0.003251
Saving checkpoint... 
Iteration: 528718986, states[0] = -86.790882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539900430, states[0] = -86.948285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551706516, states[0] = -86.767257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564506651, states[0] = 24.373321, states[40]= 0.103152
Saving checkpoint... 
Iteration: 575400282, states[0] = -86.948213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588236449, states[0] = -86.820370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599354140, states[0] = -86.929852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610003114, states[0] = 32.033941, states[40]= 0.162561
Saving checkpoint... 
Iteration: 621718015, states[0] = -86.789047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633509132, states[0] = 23.322550, states[40]= 0.056423
Saving checkpoint... 
Iteration: 645594038, states[0] = -14.748181, states[40]= 0.001462
Saving checkpoint... 
Iteration: 655394007, states[0] = -86.946111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663872979, states[0] = -86.938286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673631318, states[0] = -52.729507, states[40]= 0.000016
Saving checkpoint... 
Iteration: 684567299, states[0] = 4.421760, states[40]= 0.004529
Saving checkpoint... 
Iteration: 696676624, states[0] = -86.693628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706572977, states[0] = 1.482174, states[40]= 0.004297
Saving checkpoint... 
Iteration: 715902091, states[0] = -86.948679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726821471, states[0] = -86.910820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740053928, states[0] = 10.368762, states[40]= 0.004705
Saving checkpoint... 
Iteration: 752317050, states[0] = -86.907740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766160380, states[0] = -85.490518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777300650, states[0] = -86.895113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787901509, states[0] = -86.948446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795142657, states[0] = -66.180994, states[40]= 0.000002
Saving checkpoint... 
Iteration: 805845592, states[0] = -86.925316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814360122, states[0] = -86.932559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826405281, states[0] = -86.949577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838310485, states[0] = -86.902876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850466447, states[0] = -86.963516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862829432, states[0] = -86.915911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874029788, states[0] = 19.405406, states[40]= 0.005480
Saving checkpoint... 
Iteration: 886257722, states[0] = -86.850357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895084347, states[0] = -5.996117, states[40]= 0.003111
Saving checkpoint... 
Iteration: 906650493, states[0] = -77.097442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915112575, states[0] = -33.246779, states[40]= 0.000295
Saving checkpoint... 
Iteration: 926142005, states[0] = -65.329392, states[40]= 0.000002
Saving checkpoint... 
Iteration: 935500650, states[0] = 36.569997, states[40]= 0.008371
Saving checkpoint... 
Iteration: 948956202, states[0] = -86.961642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957817606, states[0] = -86.907985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969122478, states[0] = -43.289042, states[40]= 0.000071
Saving checkpoint... 
Iteration: 974754861, states[0] = -86.846582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986940548, states[0] = -86.958488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999734655, states[0] = -86.817239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010621482, states[0] = -42.258587, states[40]= 0.000084
Saving checkpoint... 
Iteration: 1024266021, states[0] = -86.860449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036576307, states[0] = -0.438219, states[40]= 0.004074
Saving checkpoint... 
Iteration: 1049303912, states[0] = -86.897592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060636951, states[0] = -59.111362, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1068691628, states[0] = -86.736648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078741656, states[0] = -86.827980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089123364, states[0] = -44.210824, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1102589807, states[0] = -10.696469, states[40]= 0.002146
Saving checkpoint... 
Iteration: 1113469259, states[0] = -86.963793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121966696, states[0] = -86.963364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131480583, states[0] = -86.965525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143050677, states[0] = 11.695670, states[40]= 0.004718
Saving checkpoint... 
Iteration: 1154789741, states[0] = -86.885237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164737136, states[0] = -86.821026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178278128, states[0] = -86.873775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190548818, states[0] = 12.441293, states[40]= 0.004728
Saving checkpoint... 
Iteration: 1202196773, states[0] = -86.747207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215588237, states[0] = -9.271233, states[40]= 0.002430
Saving checkpoint... 
Iteration: 1223588015, states[0] = -9.074105, states[40]= 0.002471
Saving checkpoint... 
Iteration: 1235087617, states[0] = -8.723605, states[40]= 0.002543
Saving checkpoint... 
Iteration: 1244965868, states[0] = -86.963137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255008518, states[0] = 23.475888, states[40]= 0.065677
Saving checkpoint... 
Iteration: 1267960141, states[0] = -86.962129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279730137, states[0] = -86.809698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290338793, states[0] = -86.921208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302578289, states[0] = -1.672746, states[40]= 0.003899
Saving checkpoint... 
Iteration: 1313003175, states[0] = 31.757744, states[40]= 0.163444
Saving checkpoint... 
Iteration: 1325025877, states[0] = 20.546303, states[40]= 0.006065
Saving checkpoint... 
Iteration: 1338161613, states[0] = -85.820861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347928327, states[0] = -86.955440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360524153, states[0] = 20.994633, states[40]= 0.006474
Saving checkpoint... 
Iteration: 1368799414, states[0] = -86.893652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380205998, states[0] = -86.765637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391468027, states[0] = -86.963392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404752859, states[0] = -86.843612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413501803, states[0] = 39.332912, states[40]= 0.107558
Saving checkpoint... 
Iteration: 1421765362, states[0] = -86.859383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433528327, states[0] = 19.850053, states[40]= 0.005659
Saving checkpoint... 
Iteration: 1440304070, states[0] = -86.897439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451413155, states[0] = -86.951416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461611417, states[0] = -32.088678, states[40]= 0.000338
Saving checkpoint... 
Iteration: 1475088479, states[0] = -9.487200, states[40]= 0.002386
Saving checkpoint... 
Iteration: 1488453809, states[0] = -86.960808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499794862, states[0] = -86.889629, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.843708
 - CaMKt in component CaMK (millimolar): 0.006772
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.399430
 - nass in component intracellular_ions (millimolar): 6.399488
 - ki in component intracellular_ions (millimolar): 145.584381
 - kss in component intracellular_ions (millimolar): 145.584362
 - cansr in component intracellular_ions (millimolar): 1.293457
 - cajsr in component intracellular_ions (millimolar): 1.255617
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008149
 - hf in component INa (dimensionless): 0.661143
 - hs in component INa (dimensionless): 0.661131
 - j in component INa (dimensionless): 0.661067
 - hsp in component INa (dimensionless): 0.413260
 - jp in component INa (dimensionless): 0.661023
 - mL in component INaL (dimensionless): 0.000229
 - hL in component INaL (dimensionless): 0.466108
 - hLp in component INaL (dimensionless): 0.240661
 - a in component Ito (dimensionless): 0.001073
 - iF in component Ito (dimensionless): 0.999466
 - iS in component Ito (dimensionless): 0.578029
 - ap in component Ito (dimensionless): 0.000547
 - iFp in component Ito (dimensionless): 0.999466
 - iSp in component Ito (dimensionless): 0.632443
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934975
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999892
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001525
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.405908
 - xs1 in component IKs (dimensionless): 0.243066
 - xs2 in component IKs (dimensionless): 0.000216
 - xk1 in component IK1 (dimensionless): 0.997020
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:13:57 (1661363): called boinc_finish(0)

</stderr_txt>
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