𝕏

Task 56230632

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pueyo_APDR-conf_834_1
Workunit 26706841
Created 4 Jul 2024, 21:45:29 UTC
Sent 5 Jul 2024, 12:11:44 UTC
Report deadline 8 Jul 2024, 21:47:44 UTC
Received 6 Jul 2024, 3:43:06 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237289
Run time 3 hours 8 min 26 sec
CPU time 3 hours 8 min 12 sec
Validate state Valid
Credit 67.25
Device peak FLOPS 4.27 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pueyo_APDR-conf_834.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pueyo_APDR-conf_834_1_r991457430_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pueyo_APDR-conf_834_1_r991457430_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.881292
     * GNaL_b in INaL: 0.005741
     * Gto_b in Ito: 0.084234
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031829
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.163329
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.540779
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032426
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11636658, states[0] = -62.870936, states[40]= 0.000003
Saving checkpoint... 
Iteration: 23228087, states[0] = -94.938018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34719305, states[0] = -94.902977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46285820, states[0] = -94.974471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57886297, states[0] = -95.022811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69449930, states[0] = -95.033249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81037614, states[0] = 16.034617, states[40]= 0.005379
Saving checkpoint... 
Iteration: 92628559, states[0] = -48.025378, states[40]= 0.000038
Saving checkpoint... 
Iteration: 104254831, states[0] = -94.918938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115894070, states[0] = -95.009480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127520841, states[0] = 21.012907, states[40]= 0.009045
Saving checkpoint... 
Iteration: 139139307, states[0] = -59.463373, states[40]= 0.000006
Saving checkpoint... 
Iteration: 150804420, states[0] = -94.962978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162415969, states[0] = -95.013093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174038032, states[0] = 16.011654, states[40]= 0.005356
Saving checkpoint... 
Iteration: 185659417, states[0] = -88.569569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197277982, states[0] = -94.939581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208899678, states[0] = -95.007934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220520233, states[0] = 21.161607, states[40]= 0.009516
Saving checkpoint... 
Iteration: 232059576, states[0] = 7.668937, states[40]= 0.004849
Saving checkpoint... 
Iteration: 243650934, states[0] = -74.558825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255262584, states[0] = -94.923140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266841848, states[0] = -94.984904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278441358, states[0] = -95.017942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290015572, states[0] = 22.019260, states[40]= 0.016838
Saving checkpoint... 
Iteration: 301589095, states[0] = -9.643360, states[40]= 0.002409
Saving checkpoint... 
Iteration: 313245288, states[0] = -94.901610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324910725, states[0] = -95.010759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336575449, states[0] = -0.007667, states[40]= 0.004251
Saving checkpoint... 
Iteration: 348241391, states[0] = -94.896204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359906863, states[0] = -95.009679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371486014, states[0] = -95.025202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383131553, states[0] = -50.740692, states[40]= 0.000025
Saving checkpoint... 
Iteration: 394631357, states[0] = -50.529258, states[40]= 0.000025
Saving checkpoint... 
Iteration: 406187909, states[0] = -94.798849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417849353, states[0] = -94.988483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429509098, states[0] = 23.515411, states[40]= 0.065248
Saving checkpoint... 
Iteration: 441108298, states[0] = -27.534807, states[40]= 0.000585
Saving checkpoint... 
Iteration: 452610434, states[0] = -29.562590, states[40]= 0.000488
Saving checkpoint... 
Iteration: 464171915, states[0] = -94.593414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475710595, states[0] = -94.845684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487349418, states[0] = -94.988469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498957919, states[0] = -95.020861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510555551, states[0] = 9.346415, states[40]= 0.004906
Saving checkpoint... 
Iteration: 522191557, states[0] = -94.807241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533838115, states[0] = -94.982742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545478415, states[0] = -95.024046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557125520, states[0] = -44.358367, states[40]= 0.000067
Saving checkpoint... 
Iteration: 568719985, states[0] = -94.862548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580275625, states[0] = -94.936710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591864604, states[0] = -94.995146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603457323, states[0] = -95.020691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615023365, states[0] = 20.465285, states[40]= 0.007687
Saving checkpoint... 
Iteration: 626643280, states[0] = -64.014289, states[40]= 0.000003
Saving checkpoint... 
Iteration: 638260798, states[0] = -94.920794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649881550, states[0] = -95.001569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661503323, states[0] = 35.177571, states[40]= 0.144835
Saving checkpoint... 
Iteration: 673134659, states[0] = -54.122149, states[40]= 0.000014
Saving checkpoint... 
Iteration: 684740097, states[0] = -94.894152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696377293, states[0] = -95.000013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708026991, states[0] = 19.529991, states[40]= 0.006610
Saving checkpoint... 
Iteration: 719675729, states[0] = -94.721751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731320833, states[0] = -94.972601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742967389, states[0] = -95.022268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754609111, states[0] = -28.305737, states[40]= 0.000548
Saving checkpoint... 
Iteration: 766258233, states[0] = -94.917712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777888760, states[0] = -95.003939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789468438, states[0] = -95.022403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801075238, states[0] = 0.112413, states[40]= 0.004266
Saving checkpoint... 
Iteration: 812656260, states[0] = -83.549360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824218198, states[0] = -94.859268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835823614, states[0] = -94.974262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847400090, states[0] = -95.007426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859050870, states[0] = 11.217652, states[40]= 0.004969
Saving checkpoint... 
Iteration: 870633502, states[0] = -52.855170, states[40]= 0.000017
Saving checkpoint... 
Iteration: 882230956, states[0] = -94.880387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893815206, states[0] = -94.968852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905443246, states[0] = -95.017890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916935125, states[0] = -95.016215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928553072, states[0] = 10.346460, states[40]= 0.004939
Saving checkpoint... 
Iteration: 940162051, states[0] = -91.462370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951737974, states[0] = -94.890923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963364523, states[0] = -94.994875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974989554, states[0] = -95.025276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986614696, states[0] = -33.632045, states[40]= 0.000309
Saving checkpoint... 
Iteration: 998207433, states[0] = -94.839348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009786861, states[0] = -94.946964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021336951, states[0] = -94.981807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032906150, states[0] = -95.009049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044564117, states[0] = 5.683801, states[40]= 0.004760
Saving checkpoint... 
Iteration: 1056212998, states[0] = -94.849771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067754178, states[0] = -94.912611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079341528, states[0] = -94.984180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090966829, states[0] = -95.021957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102617398, states[0] = -36.239929, states[40]= 0.000220
Saving checkpoint... 
Iteration: 1114262321, states[0] = -94.922234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125911673, states[0] = -95.010493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137560678, states[0] = 7.199693, states[40]= 0.004831
Saving checkpoint... 
Iteration: 1149208692, states[0] = -94.841658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160784242, states[0] = -94.944520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172427711, states[0] = -95.014415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184086306, states[0] = -7.334120, states[40]= 0.002901
Saving checkpoint... 
Iteration: 1195743988, states[0] = -94.899263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207402547, states[0] = -95.007914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219062331, states[0] = 6.479884, states[40]= 0.004799
Saving checkpoint... 
Iteration: 1230723271, states[0] = -94.867722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242360438, states[0] = -94.992976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253962259, states[0] = -95.021113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265618357, states[0] = -37.173544, states[40]= 0.000193
Saving checkpoint... 
Iteration: 1277266143, states[0] = -94.926389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288878452, states[0] = -95.000056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300514707, states[0] = 22.163306, states[40]= 0.019515
Saving checkpoint... 
Iteration: 1312133564, states[0] = -52.922470, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1323707323, states[0] = -94.838928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335304664, states[0] = -94.961170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346912442, states[0] = -95.010555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358534741, states[0] = 17.150292, states[40]= 0.005580
Saving checkpoint... 
Iteration: 1370152177, states[0] = -76.545938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381761401, states[0] = -94.921012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393359898, states[0] = -94.992647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405022912, states[0] = 20.572876, states[40]= 0.007881
Saving checkpoint... 
Iteration: 1416685272, states[0] = -94.791136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428335010, states[0] = -94.980493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439921237, states[0] = -95.012720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451499869, states[0] = -95.026228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463058074, states[0] = 8.304885, states[40]= 0.004872
Saving checkpoint... 
Iteration: 1474778564, states[0] = -94.939009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486307815, states[0] = -94.963367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497890431, states[0] = -95.004024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509452661, states[0] = -94.912666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520999820, states[0] = -95.268888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532570484, states[0] = -95.100693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1544093793, states[0] = -95.283627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555665751, states[0] = -95.101502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567224009, states[0] = 19.541900, states[40]= 0.008625
Saving checkpoint... 
Iteration: 1578779858, states[0] = -95.143822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590339502, states[0] = 12.846482, states[40]= 0.006110
Saving checkpoint... 
Iteration: 1601849569, states[0] = -94.946355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613424111, states[0] = 19.434073, states[40]= 0.008570
Saving checkpoint... 
Iteration: 1624989235, states[0] = -95.169274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636560033, states[0] = 1.487998, states[40]= 0.005005
Saving checkpoint... 
Iteration: 1648141570, states[0] = -95.254018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659727283, states[0] = -73.038079, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1671246473, states[0] = -95.259984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1682752073, states[0] = 6.254028, states[40]= 0.005485
Saving checkpoint... 
Iteration: 1694274769, states[0] = -95.137576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705760509, states[0] = -95.274747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717278591, states[0] = -14.777558, states[40]= 0.001691
Saving checkpoint... 
Iteration: 1728787997, states[0] = -95.167869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740294234, states[0] = -95.301985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751814964, states[0] = -55.972903, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1763331172, states[0] = -95.241481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774834712, states[0] = 15.042145, states[40]= 0.006497
Saving checkpoint... 
Iteration: 1786312968, states[0] = -53.500846, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1797794958, states[0] = -95.182183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809263720, states[0] = -94.971434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820742735, states[0] = -94.934393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832249604, states[0] = -94.933664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843742980, states[0] = -94.917093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855228387, states[0] = -94.889737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866716219, states[0] = -94.865075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878202729, states[0] = -94.836659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889704411, states[0] = -94.837925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901219874, states[0] = -94.865065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912748620, states[0] = -94.907511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924273299, states[0] = -94.935273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935785523, states[0] = -94.946413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947298764, states[0] = -94.957145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958787694, states[0] = -94.947690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970245889, states[0] = -94.901763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981731393, states[0] = -94.880644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993239859, states[0] = -94.893158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004757245, states[0] = -94.915856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016299655, states[0] = -94.957001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027820623, states[0] = -94.971669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039307501, states[0] = -94.962793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050794042, states[0] = -94.952412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062284097, states[0] = -94.943786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073797294, states[0] = -94.955008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085291073, states[0] = -94.949883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096784812, states[0] = -94.944392, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.901660
 - CaMKt in component CaMK (millimolar): 0.006973
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.574337
 - nass in component intracellular_ions (millimolar): 6.574397
 - ki in component intracellular_ions (millimolar): 145.403196
 - kss in component intracellular_ions (millimolar): 145.403176
 - cansr in component intracellular_ions (millimolar): 1.312134
 - cajsr in component intracellular_ions (millimolar): 1.274187
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003619
 - hf in component INa (dimensionless): 0.879997
 - hs in component INa (dimensionless): 0.879993
 - j in component INa (dimensionless): 0.879964
 - hsp in component INa (dimensionless): 0.725824
 - jp in component INa (dimensionless): 0.879945
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709959
 - hLp in component INaL (dimensionless): 0.452133
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621478
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696398
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935530
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001603
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330897
 - xs1 in component IKs (dimensionless): 0.240958
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:24:49 (5281): called boinc_finish(0)

</stderr_txt>
]]>


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