𝕏

Task 56230515

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_6000-conf_134_1
Workunit 26706783
Created 4 Jul 2024, 21:45:24 UTC
Sent 5 Jul 2024, 12:11:53 UTC
Report deadline 8 Jul 2024, 12:11:53 UTC
Received 7 Jul 2024, 10:49:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239744
Run time 2 hours 26 min 23 sec
CPU time 2 hours 9 min 43 sec
Validate state Valid
Credit 44.92
Device peak FLOPS 2.97 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 3.94 MB
Peak swap size 1.79 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_6000-conf_134.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_6000-conf_134_1_r389048284_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_6000-conf_134_1_r389048284_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.226591
     * GNaL_b in INaL: 0.005826
     * Gto_b in Ito: 0.083876
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031754
     * GKs_b in IKs: 0.001926
     * GK1_b in IK1: 0.163558
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.478970
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032483
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12913260, states[0] = -94.209674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26010577, states[0] = -94.162870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 38499670, states[0] = -94.173759, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50969780, states[0] = -94.182412, states[40]= 0.000001
Saving checkpoint... 
Iteration: 63906605, states[0] = -94.222324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 77033301, states[0] = -94.203269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90020776, states[0] = 33.358672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103083742, states[0] = -94.232559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 116479974, states[0] = -94.210915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 129900046, states[0] = -94.241626, states[40]= 0.000001
Saving checkpoint... 
Iteration: 143026690, states[0] = -94.218077, states[40]= 0.000001
Saving checkpoint... 
Iteration: 156050077, states[0] = 32.340921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169181469, states[0] = -94.237162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 182241775, states[0] = -94.218122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 195566716, states[0] = -94.208225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208777916, states[0] = -94.224119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 221735929, states[0] = -94.216013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234763999, states[0] = -94.244208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 248077281, states[0] = -94.220384, states[40]= 0.000001
Saving checkpoint... 
Iteration: 261743016, states[0] = -94.243085, states[40]= 0.000001
Saving checkpoint... 
Iteration: 275040732, states[0] = -94.220733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 288170629, states[0] = -12.515647, states[40]= 0.000623
Saving checkpoint... 
Iteration: 300619472, states[0] = -94.225691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 313105351, states[0] = -94.240428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 326233650, states[0] = -94.218625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 339258465, states[0] = -56.480609, states[40]= 0.000194
Saving checkpoint... 
Iteration: 352388703, states[0] = -94.231951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 365170161, states[0] = -94.218942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 377811385, states[0] = -94.215255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390080612, states[0] = 23.307109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402975776, states[0] = -94.243536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 415885202, states[0] = -94.221855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 428715328, states[0] = -94.215225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 441336974, states[0] = -93.855242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454273213, states[0] = -94.234459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 467270270, states[0] = -94.217418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 480309301, states[0] = -93.730319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492836814, states[0] = -94.244608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 500648662, states[0] = -94.214996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 510622964, states[0] = -94.225209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 520622965, states[0] = -94.225511, states[40]= 0.000001
Saving checkpoint... 
Iteration: 530546495, states[0] = -94.215251, states[40]= 0.000001
Saving checkpoint... 
Iteration: 538854763, states[0] = -94.221462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 546953876, states[0] = -94.243077, states[40]= 0.000001
Saving checkpoint... 
Iteration: 556041929, states[0] = -94.240743, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564822266, states[0] = -94.243988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 572132664, states[0] = -94.217918, states[40]= 0.000001
Saving checkpoint... 
Iteration: 578144063, states[0] = -94.217768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 584453346, states[0] = -94.215387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 590559943, states[0] = -94.214782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 596393039, states[0] = -94.215675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 602080099, states[0] = -94.218247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 607465843, states[0] = -94.228336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 612941080, states[0] = -94.242898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 620357543, states[0] = -94.215750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 628649241, states[0] = -94.224278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636705526, states[0] = -94.237753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 646087720, states[0] = -94.238781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651841606, states[0] = -94.243569, states[40]= 0.000001
Saving checkpoint... 
Iteration: 658473774, states[0] = -94.227806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 662263016, states[0] = -94.216165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 668337312, states[0] = -94.215567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 675163328, states[0] = -8.494029, states[40]= 0.000533
Saving checkpoint... 
Iteration: 682697757, states[0] = -94.223021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689521534, states[0] = -94.214308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 698540009, states[0] = -94.214153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 707451662, states[0] = -94.214570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 714027713, states[0] = 34.126460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719899055, states[0] = -94.212741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 730848447, states[0] = -94.220264, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_6000-conf_134.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_6000-conf_134_1_r389048284_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_6000-conf_134_1_r389048284_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.226591
     * GNaL_b in INaL: 0.005826
     * Gto_b in Ito: 0.083876
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031754
     * GKs_b in IKs: 0.001926
     * GK1_b in IK1: 0.163558
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.478970
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032483
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 730848447
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.220264 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 744975471, states[0] = -94.241254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 759123658, states[0] = 7.864644, states[40]= 0.000059
Saving checkpoint... 
Iteration: 772837754, states[0] = -94.220139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 784196682, states[0] = -94.234520, states[40]= 0.000001
Saving checkpoint... 
Iteration: 797627462, states[0] = -94.213087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811651745, states[0] = -94.223001, states[40]= 0.000001
Saving checkpoint... 
Iteration: 825873107, states[0] = -94.242381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 839527164, states[0] = -94.213271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 853325892, states[0] = -94.230291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867180599, states[0] = -17.613821, states[40]= 0.001313
Saving checkpoint... 
Iteration: 879338795, states[0] = -93.859311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892060137, states[0] = -94.237957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 905126550, states[0] = -94.215740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 918191145, states[0] = -21.290265, states[40]= 0.003552
Saving checkpoint... 
Iteration: 931312136, states[0] = -94.230150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944618954, states[0] = -94.212134, states[40]= 0.000001
Saving checkpoint... 
Iteration: 958303404, states[0] = -94.230214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 972193549, states[0] = -21.957557, states[40]= 0.004093
Saving checkpoint... 
Iteration: 986487694, states[0] = -94.212491, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1000792129, states[0] = -94.219303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1015643564, states[0] = -94.221786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1030580022, states[0] = -94.222953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1045259086, states[0] = -94.230905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1058011555, states[0] = -94.215940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1070678449, states[0] = -94.211046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1081643648, states[0] = -94.221342, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1092518282, states[0] = -94.177920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103389148, states[0] = -94.212292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1114261678, states[0] = -94.230366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1125203714, states[0] = -24.790548, states[40]= 0.005612
Saving checkpoint... 
Iteration: 1136151169, states[0] = -94.213950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1147034886, states[0] = -94.236981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1157925459, states[0] = -94.209737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166483309, states[0] = -94.211305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1171901930, states[0] = -94.216549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1182619654, states[0] = -94.219886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193513571, states[0] = -94.210961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1204398621, states[0] = -94.225993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1213000020, states[0] = -94.237496, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1223342295, states[0] = -94.211802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1233812240, states[0] = -94.239353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1245413777, states[0] = -94.059477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257324183, states[0] = -93.796038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268403541, states[0] = -94.211090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1278412943, states[0] = -94.057747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290530707, states[0] = -94.184239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298865311, states[0] = -94.208928, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1307150623, states[0] = -94.212806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1317128548, states[0] = 6.111002, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1327137967, states[0] = -94.232674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1336694034, states[0] = -94.218695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1346317804, states[0] = -94.211149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1355820580, states[0] = -94.208663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1364675819, states[0] = -94.209079, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1372736666, states[0] = -94.217709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381362941, states[0] = -94.225739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1390061611, states[0] = -94.234572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1398024367, states[0] = 33.814690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406077123, states[0] = -94.212875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1413808170, states[0] = -94.238071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419490590, states[0] = -94.155048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426038052, states[0] = -94.235018, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1432408185, states[0] = -94.224217, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1438850179, states[0] = -94.215481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445666589, states[0] = -94.208570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1453243027, states[0] = -94.228639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459994095, states[0] = -94.213443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464614984, states[0] = -94.216803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1469503703, states[0] = -94.209157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1477552375, states[0] = -94.220534, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1487330683, states[0] = -94.210109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1496771717, states[0] = -94.207859, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.083274
 - CaMKt in component CaMK (millimolar): 0.001351
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 7.716309
 - nass in component intracellular_ions (millimolar): 7.716457
 - ki in component intracellular_ions (millimolar): 144.122778
 - kss in component intracellular_ions (millimolar): 144.122765
 - cansr in component intracellular_ions (millimolar): 1.760859
 - cajsr in component intracellular_ions (millimolar): 1.762066
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003930
 - hf in component INa (dimensionless): 0.865054
 - hs in component INa (dimensionless): 0.865054
 - j in component INa (dimensionless): 0.865055
 - hsp in component INa (dimensionless): 0.698294
 - jp in component INa (dimensionless): 0.865055
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707046
 - hLp in component INaL (dimensionless): 0.513264
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999131
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999679
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999266
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004202
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000651
 - xs1 in component IKs (dimensionless): 0.019837
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997544
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:17:08 (4028): called boinc_finish(0)

</stderr_txt>
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