𝕏

Task 56230316

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_3000-conf_234_0
Workunit 26706684
Created 4 Jul 2024, 21:45:19 UTC
Sent 5 Jul 2024, 12:11:53 UTC
Report deadline 8 Jul 2024, 12:11:53 UTC
Received 8 Jul 2024, 9:45:24 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239744
Run time 2 hours 18 min 52 sec
CPU time 2 hours 3 min 23 sec
Validate state Valid
Credit 44.88
Device peak FLOPS 2.97 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 3.96 MB
Peak swap size 1.79 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_3000-conf_234.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_3000-conf_234_0_r2026108610_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_3000-conf_234_0_r2026108610_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.081514
     * GNaL_b in INaL: 0.005729
     * Gto_b in Ito: 0.084675
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031805
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.164540
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.274283
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032554
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9953914, states[0] = -94.389411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19905024, states[0] = -94.286825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29823877, states[0] = -94.301003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39593079, states[0] = -94.315050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48746180, states[0] = -94.315390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58080786, states[0] = -94.302645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67253717, states[0] = -94.298767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76567154, states[0] = 19.614276, states[40]= 0.000002
Saving checkpoint... 
Iteration: 84994292, states[0] = -94.315867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93361939, states[0] = -94.227147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101862137, states[0] = -94.305344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109905785, states[0] = -94.274772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117744457, states[0] = -94.334308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125617291, states[0] = -94.318349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132887443, states[0] = -94.329820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139655985, states[0] = -55.300875, states[40]= 0.000057
Saving checkpoint... 
Iteration: 148701616, states[0] = -93.620804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158210212, states[0] = -94.338385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165696727, states[0] = -94.338866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171329509, states[0] = -94.185008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179026919, states[0] = -94.329766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185986066, states[0] = -94.307940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192407021, states[0] = -94.280618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200851971, states[0] = -94.312125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208587212, states[0] = 10.167311, states[40]= 0.000037
Saving checkpoint... 
Iteration: 215460476, states[0] = -94.328218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221956427, states[0] = -94.308717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225888009, states[0] = -94.331650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229931058, states[0] = -94.296444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234570582, states[0] = -94.335475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239110097, states[0] = -94.338092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250064760, states[0] = -94.322953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261988536, states[0] = -94.326331, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_3000-conf_234.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_3000-conf_234_0_r2026108610_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_3000-conf_234_0_r2026108610_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.081514
     * GNaL_b in INaL: 0.005729
     * Gto_b in Ito: 0.084675
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031805
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.164540
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.274283
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032554
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 261988536
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.326331 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 271860094, states[0] = -94.232485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279409708, states[0] = -94.281762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288434051, states[0] = -94.297330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298380971, states[0] = -94.310002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307814989, states[0] = -94.154266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317005379, states[0] = -94.323890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326926732, states[0] = -94.308087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336995807, states[0] = -94.324779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346717692, states[0] = -93.742391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356019747, states[0] = -94.326361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365271369, states[0] = -94.334738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373553277, states[0] = 23.625278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382206737, states[0] = -94.314804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390378621, states[0] = -94.252298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398762000, states[0] = -94.312411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407166327, states[0] = -94.336453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415214783, states[0] = -94.313918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423808503, states[0] = -94.332200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432441112, states[0] = -94.298676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441582729, states[0] = -94.333149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450821509, states[0] = -94.331159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458838151, states[0] = -94.308676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467685719, states[0] = -94.314163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476627748, states[0] = -94.316410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485417361, states[0] = -94.326017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493607086, states[0] = -2.521974, states[40]= 0.000248
Saving checkpoint... 
Iteration: 501018780, states[0] = 24.021345, states[40]= -0.000000
Saving checkpoint... 
Iteration: 508253397, states[0] = -94.310843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515174014, states[0] = -94.334568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523349377, states[0] = -94.307185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532215486, states[0] = -94.311872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539747784, states[0] = -94.310507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548626409, states[0] = -94.315222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557607138, states[0] = -94.315897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564875941, states[0] = -94.326648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573670826, states[0] = -94.333574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582756134, states[0] = -94.331551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591147917, states[0] = -46.013053, states[40]= 0.000169
Saving checkpoint... 
Iteration: 601909220, states[0] = -94.275888, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_3000-conf_234.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_3000-conf_234_0_r2026108610_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_3000-conf_234_0_r2026108610_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.081514
     * GNaL_b in INaL: 0.005729
     * Gto_b in Ito: 0.084675
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031805
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.164540
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.274283
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032554
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 601909220
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.275888 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 602427984, states[0] = -94.323482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610456766, states[0] = -94.302299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611586053, states[0] = -94.315901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624494874, states[0] = -94.315929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638171060, states[0] = -94.332469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650937080, states[0] = -94.302189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663785755, states[0] = -94.329033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676535713, states[0] = 26.010473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690565620, states[0] = -94.327341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703400716, states[0] = -94.302412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715871347, states[0] = -94.238660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728547249, states[0] = -94.315632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741523426, states[0] = -94.320435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754096481, states[0] = -94.312979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767294037, states[0] = -94.326907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780905864, states[0] = -94.321484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795354048, states[0] = -94.215303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810292677, states[0] = -94.088626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825657552, states[0] = -94.329237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841280167, states[0] = -94.304114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856404033, states[0] = -94.299662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871197273, states[0] = -94.306743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886135672, states[0] = -94.309014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902205415, states[0] = -94.327495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917335221, states[0] = -94.322503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932118068, states[0] = -94.326652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946354708, states[0] = -94.299707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960989201, states[0] = -94.314340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976521827, states[0] = 24.730499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991969826, states[0] = -94.301618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007891546, states[0] = -94.297446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023775370, states[0] = -94.323242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039224970, states[0] = -94.302759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054181993, states[0] = -94.304194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069896552, states[0] = -94.257657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085958641, states[0] = -94.294027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102322690, states[0] = -94.298101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118599281, states[0] = -94.306571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134917483, states[0] = -94.314819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152898660, states[0] = -94.315424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172235795, states[0] = -94.322071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188292738, states[0] = -94.082197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202599382, states[0] = -94.305124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215905335, states[0] = -94.314016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229017613, states[0] = -94.310897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241913693, states[0] = -94.292707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254528591, states[0] = -94.312542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267588510, states[0] = 9.472243, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1280740703, states[0] = -94.297994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293821326, states[0] = -94.316651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306821262, states[0] = -94.150342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319688930, states[0] = -94.299343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332747134, states[0] = -94.318946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345890871, states[0] = -94.247841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358949375, states[0] = -94.289595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371382646, states[0] = -94.239482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384215798, states[0] = -94.297164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397882502, states[0] = -94.291005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412083907, states[0] = -94.316534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425832007, states[0] = -94.313891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439907175, states[0] = -94.289491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453709795, states[0] = -93.665568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467782318, states[0] = -94.315318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481976491, states[0] = -94.286668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496229989, states[0] = -94.316658, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.161642
 - CaMKt in component CaMK (millimolar): 0.003692
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.247965
 - nass in component intracellular_ions (millimolar): 7.248106
 - ki in component intracellular_ions (millimolar): 144.375306
 - kss in component intracellular_ions (millimolar): 144.375288
 - cansr in component intracellular_ions (millimolar): 2.475677
 - cajsr in component intracellular_ions (millimolar): 2.476352
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003899
 - hf in component INa (dimensionless): 0.866551
 - hs in component INa (dimensionless): 0.866552
 - j in component INa (dimensionless): 0.866559
 - hsp in component INa (dimensionless): 0.701007
 - jp in component INa (dimensionless): 0.866562
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709290
 - hLp in component INaL (dimensionless): 0.513255
 - a in component Ito (dimensionless): 0.000655
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.999852
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999852
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991128
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005383
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.024893
 - xs1 in component IKs (dimensionless): 0.069063
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997525
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:15:14 (4908): called boinc_finish(0)

</stderr_txt>
]]>