𝕏

Task 56230243

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_6000-conf_434_1
Workunit 26706647
Created 4 Jul 2024, 21:45:19 UTC
Sent 5 Jul 2024, 12:11:05 UTC
Report deadline 8 Jul 2024, 12:11:05 UTC
Received 6 Jul 2024, 13:57:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231343
Run time 51 min 4 sec
CPU time 41 min 52 sec
Validate state Valid
Credit 44.41
Device peak FLOPS 5.12 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.69 MB
Peak swap size 5.27 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_6000-conf_434.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_6000-conf_434_1_r344627328_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_6000-conf_434_1_r344627328_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.706139
     * GNaL_b in INaL: 0.005804
     * Gto_b in Ito: 0.084056
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031938
     * GKs_b in IKs: 0.001936
     * GK1_b in IK1: 0.163886
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.509113
     * GKb_b in IKb: 0.003803
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033845
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 6921342, states[0] = -94.122783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16503683, states[0] = -94.016369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26176285, states[0] = -93.955877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35983262, states[0] = -93.923859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44090507, states[0] = -93.919719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53529929, states[0] = -93.908389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63120459, states[0] = -7.749363, states[40]= 0.002941
Saving checkpoint... 
Iteration: 72777458, states[0] = -93.939805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82391660, states[0] = -93.919789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91996745, states[0] = -93.906676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101863208, states[0] = -93.898059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108654205, states[0] = -93.932838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118307723, states[0] = -93.920704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128305253, states[0] = -93.901800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138288001, states[0] = -93.574037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147974884, states[0] = -93.932085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157541769, states[0] = -93.913704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167371313, states[0] = -93.900735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177076531, states[0] = 15.302436, states[40]= 0.001406
Saving checkpoint... 
Iteration: 186924438, states[0] = -93.933554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196502049, states[0] = -93.914469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206497746, states[0] = -93.899413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216298888, states[0] = -93.610800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226004061, states[0] = -93.930637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235599119, states[0] = -93.912040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245462723, states[0] = -93.899612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254970853, states[0] = -93.896057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264930133, states[0] = -93.933152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274797408, states[0] = -93.907979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284584941, states[0] = -93.898524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294154607, states[0] = -33.683834, states[40]= 0.001809
Saving checkpoint... 
Iteration: 304041533, states[0] = -93.929090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313869845, states[0] = -93.906670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323416599, states[0] = -93.899882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330860193, states[0] = -93.935051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340918641, states[0] = -93.905844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350469886, states[0] = -93.899360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360075497, states[0] = 15.712792, states[40]= 0.001340
Saving checkpoint... 
Iteration: 369926165, states[0] = -93.933101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379548668, states[0] = -93.912950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394786929, states[0] = -93.907965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404547776, states[0] = -93.898618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414202133, states[0] = -72.395929, states[40]= 0.000006
Saving checkpoint... 
Iteration: 424102155, states[0] = -93.926630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433787724, states[0] = -93.907887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443590971, states[0] = -93.898213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453575994, states[0] = -93.919849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463634026, states[0] = -93.910875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473646731, states[0] = -93.897744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483395013, states[0] = -93.811429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493028936, states[0] = -93.929251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499847517, states[0] = -93.906738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509189423, states[0] = -93.901927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518450240, states[0] = -93.899261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527784020, states[0] = -93.896711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537542152, states[0] = -93.910857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547326745, states[0] = -93.918727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554100777, states[0] = -93.902932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563881957, states[0] = -93.896047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573750274, states[0] = -93.935594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583237137, states[0] = -93.921565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592790249, states[0] = -93.907585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602614324, states[0] = -93.897778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612180241, states[0] = -53.297984, states[40]= 0.000148
Saving checkpoint... 
Iteration: 621769789, states[0] = -93.935669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631560725, states[0] = -93.912257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641084625, states[0] = -93.903000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650680201, states[0] = -93.897216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660219122, states[0] = -91.221932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669777626, states[0] = -93.935604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679350490, states[0] = -93.917792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689015528, states[0] = -93.903852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698574082, states[0] = -93.897933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708068353, states[0] = 18.456701, states[40]= 0.000940
Saving checkpoint... 
Iteration: 717651233, states[0] = -93.930678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727237393, states[0] = -93.921325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736823988, states[0] = -93.906757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746638329, states[0] = -93.897365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756006891, states[0] = 30.297670, states[40]= 0.173420
Saving checkpoint... 
Iteration: 765353874, states[0] = -93.747379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774787642, states[0] = -93.935415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784377983, states[0] = -93.916809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793809907, states[0] = -93.906911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803376192, states[0] = -93.899483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812675491, states[0] = -93.896988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822098479, states[0] = 5.743184, states[40]= 0.003169
Saving checkpoint... 
Iteration: 831574254, states[0] = -93.918855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841476182, states[0] = -93.914011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851153928, states[0] = -93.901795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861426445, states[0] = -93.844939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871385734, states[0] = -93.916444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881529815, states[0] = -93.897994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891109071, states[0] = 0.076159, states[40]= 0.003727
Saving checkpoint... 
Iteration: 901021992, states[0] = -93.928852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910893289, states[0] = -93.905323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920938257, states[0] = -93.895146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930928649, states[0] = -93.932116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940986156, states[0] = -93.903863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950840923, states[0] = -93.895669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960994274, states[0] = -93.929777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970871091, states[0] = -93.905586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980780241, states[0] = -93.896004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990884372, states[0] = -93.933366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000704061, states[0] = -93.908558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010493319, states[0] = -93.898091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020137800, states[0] = -21.343158, states[40]= 0.002018
Saving checkpoint... 
Iteration: 1030158090, states[0] = -93.923607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039873038, states[0] = -93.905442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049509669, states[0] = -93.897890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059273416, states[0] = -93.515845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068979613, states[0] = -93.930134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078907817, states[0] = -93.904821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088690719, states[0] = -93.896435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098352046, states[0] = -93.743372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108179113, states[0] = -93.922730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117902627, states[0] = -93.904840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127845713, states[0] = -93.895354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137714861, states[0] = -93.933881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147644504, states[0] = -93.909547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157461095, states[0] = -93.898133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167129379, states[0] = -14.712374, states[40]= 0.001850
Saving checkpoint... 
Iteration: 1176895208, states[0] = -93.932759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186417868, states[0] = -93.915025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196066314, states[0] = -93.902344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205650663, states[0] = -93.896533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215344007, states[0] = -93.727175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225088429, states[0] = -93.925850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234834312, states[0] = -93.905776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244329828, states[0] = -93.899226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254254646, states[0] = -93.432652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264028154, states[0] = -93.928039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273708476, states[0] = -93.908030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284109494, states[0] = -0.174351, states[40]= 0.003730
Saving checkpoint... 
Iteration: 1294090031, states[0] = -93.925679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303698836, states[0] = -93.908173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313365294, states[0] = -93.898765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323783648, states[0] = -93.934545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334211882, states[0] = -93.900338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344081560, states[0] = 13.277689, states[40]= 0.001762
Saving checkpoint... 
Iteration: 1353877227, states[0] = -93.932975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363569450, states[0] = -93.910872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373561324, states[0] = -93.896945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383542653, states[0] = -93.909649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393210608, states[0] = -93.921167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402091319, states[0] = -93.925457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411808336, states[0] = -93.905942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421488335, states[0] = -93.897470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431045758, states[0] = 26.295723, states[40]= 0.000268
Saving checkpoint... 
Iteration: 1440751359, states[0] = -93.934213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450479165, states[0] = -93.912952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460317469, states[0] = -93.899002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470029069, states[0] = 30.645237, states[40]= 0.000183
Saving checkpoint... 
Iteration: 1479649392, states[0] = -93.929279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489306103, states[0] = -93.917853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499003892, states[0] = -93.902709, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.769852
 - CaMKt in component CaMK (millimolar): 0.001314
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.689022
 - nass in component intracellular_ions (millimolar): 6.689146
 - ki in component intracellular_ions (millimolar): 145.175613
 - kss in component intracellular_ions (millimolar): 145.175604
 - cansr in component intracellular_ions (millimolar): 1.831283
 - cajsr in component intracellular_ions (millimolar): 1.831159
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004056
 - hf in component INa (dimensionless): 0.858929
 - hs in component INa (dimensionless): 0.858929
 - j in component INa (dimensionless): 0.858930
 - hsp in component INa (dimensionless): 0.687336
 - jp in component INa (dimensionless): 0.858931
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.698312
 - hLp in component INaL (dimensionless): 0.502850
 - a in component Ito (dimensionless): 0.000673
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.999224
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.999698
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999520
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005458
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000589
 - xs1 in component IKs (dimensionless): 0.014763
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997619
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:57:00 (3248): called boinc_finish(0)

</stderr_txt>
]]>


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