𝕏

Task 56224131

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_5000-conf_228_1
Workunit 26703594
Created 4 Jul 2024, 21:42:34 UTC
Sent 5 Jul 2024, 11:35:19 UTC
Report deadline 8 Jul 2024, 11:35:19 UTC
Received 6 Jul 2024, 1:55:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227546
Run time 1 hours 17 min 24 sec
CPU time 51 min 25 sec
Validate state Valid
Credit 46.58
Device peak FLOPS 4.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 8.82 MB
Peak swap size 32.86 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_5000-conf_228.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_5000-conf_228_1_r915782307_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_MID_5000-conf_228_1_r915782307_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.235117
     * GNaL_b in INaL: 0.005828
     * Gto_b in Ito: 0.083990
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031748
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.164736
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.201738
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032571
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17285385, states[0] = -94.191675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33428210, states[0] = -94.227000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50700604, states[0] = -94.233124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66186131, states[0] = -94.241432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 87774633, states[0] = -68.996372, states[40]= 0.000030
Saving checkpoint... 
Iteration: 105747884, states[0] = -94.261959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 122806378, states[0] = -93.739819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140942500, states[0] = -94.268574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 160808461, states[0] = -94.270865, states[40]= 0.000001
Saving checkpoint... 
Iteration: 181966997, states[0] = -94.246793, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198470529, states[0] = -94.270507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 218234863, states[0] = -94.269453, states[40]= 0.000001
Saving checkpoint... 
Iteration: 239710455, states[0] = -94.244880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255427780, states[0] = -94.120535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268238017, states[0] = -94.269634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 284090005, states[0] = -94.253421, states[40]= 0.000001
Saving checkpoint... 
Iteration: 300490856, states[0] = -94.192046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320679395, states[0] = -94.263864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 339558545, states[0] = -94.245789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 356707343, states[0] = -94.250612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 371522864, states[0] = -94.254214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 389792586, states[0] = -94.243244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 409777240, states[0] = -94.243189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 429701727, states[0] = -94.243634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 446961702, states[0] = -94.246008, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462385930, states[0] = -94.241973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 479848244, states[0] = -94.242070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495909417, states[0] = -94.270149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513537018, states[0] = -94.266857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 533261835, states[0] = -94.268742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 549005792, states[0] = -94.253073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562429908, states[0] = -94.240834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 580231174, states[0] = -39.573549, states[40]= 0.002167
Saving checkpoint... 
Iteration: 598338092, states[0] = -94.269794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610652925, states[0] = -94.257444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 622112459, states[0] = -94.242794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 634295230, states[0] = -94.246734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 645473061, states[0] = -94.173106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657848721, states[0] = -93.931961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671773639, states[0] = -94.246755, states[40]= 0.000001
Saving checkpoint... 
Iteration: 684158266, states[0] = -94.248687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 693859992, states[0] = -94.255494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 708072767, states[0] = -94.235530, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720375167, states[0] = -94.010789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730940727, states[0] = -94.267515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 742704447, states[0] = -26.283509, states[40]= 0.005923
Saving checkpoint... 
Iteration: 752205756, states[0] = -94.240796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761963152, states[0] = -94.243252, states[40]= 0.000001
Saving checkpoint... 
Iteration: 770587692, states[0] = -94.240254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 782993253, states[0] = -94.189868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796987670, states[0] = -94.242646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 809014642, states[0] = -94.250610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819616678, states[0] = -94.241035, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831528102, states[0] = -94.250109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 844214925, states[0] = -94.246255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857359495, states[0] = -94.238710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 868230165, states[0] = -94.264067, states[40]= 0.000001
Saving checkpoint... 
Iteration: 878956524, states[0] = -94.251381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 887766766, states[0] = -68.188574, states[40]= 0.000034
Saving checkpoint... 
Iteration: 901571209, states[0] = -94.248554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 914852978, states[0] = -94.238253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930003889, states[0] = 20.784033, states[40]= 0.808288
Saving checkpoint... 
Iteration: 937920858, states[0] = -94.103912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951649011, states[0] = -94.246538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 964889132, states[0] = -94.237581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980133607, states[0] = 3.738288, states[40]= 0.000155
Saving checkpoint... 
Iteration: 993890558, states[0] = -94.252064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1004152604, states[0] = -94.246013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1016505163, states[0] = -94.249024, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1031596664, states[0] = -94.246888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1044907740, states[0] = -94.236769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1058931993, states[0] = -94.250426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1072771148, states[0] = -73.824871, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1084666085, states[0] = -94.238255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1100667574, states[0] = -94.255507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1114268143, states[0] = -94.242997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1131675586, states[0] = -94.244469, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1144107092, states[0] = -94.245696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155261573, states[0] = -62.850932, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1166645135, states[0] = -94.244743, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181784845, states[0] = -94.242137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193895298, states[0] = -94.250199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1204257021, states[0] = -94.242398, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215934680, states[0] = -94.263429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230939743, states[0] = -94.263193, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1245068297, states[0] = 27.202912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261277865, states[0] = -94.252897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1272355996, states[0] = -94.235121, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1283475872, states[0] = -94.261884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1297286831, states[0] = -94.235397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1312997840, states[0] = -94.188858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328648337, states[0] = -94.256303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1339042859, states[0] = -94.245367, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1350833437, states[0] = -94.263243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1363436740, states[0] = -94.262108, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377386602, states[0] = -94.234007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1393363723, states[0] = -94.262865, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1405253179, states[0] = -55.721822, states[40]= 0.000235
Saving checkpoint... 
Iteration: 1417721178, states[0] = -33.575466, states[40]= 0.004076
Saving checkpoint... 
Iteration: 1435256656, states[0] = -58.539085, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1448830997, states[0] = -94.249736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1463372650, states[0] = -94.262200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474407778, states[0] = -94.237775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1487698236, states[0] = -24.265755, states[40]= 0.005498
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.108265
 - CaMKt in component CaMK (millimolar): 0.001787
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 7.771156
 - nass in component intracellular_ions (millimolar): 7.771309
 - ki in component intracellular_ions (millimolar): 144.045870
 - kss in component intracellular_ions (millimolar): 144.045856
 - cansr in component intracellular_ions (millimolar): 1.794131
 - cajsr in component intracellular_ions (millimolar): 1.795595
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003920
 - hf in component INa (dimensionless): 0.865533
 - hs in component INa (dimensionless): 0.865533
 - j in component INa (dimensionless): 0.865534
 - hsp in component INa (dimensionless): 0.699160
 - jp in component INa (dimensionless): 0.865535
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707748
 - hLp in component INaL (dimensionless): 0.513992
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.997200
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999034
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998032
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004365
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002432
 - xs1 in component IKs (dimensionless): 0.032628
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997538
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
20:53:56 (33198): called boinc_finish(0)

</stderr_txt>
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