𝕏

Task 56223421

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_8000-conf_627_1
Workunit 26703239
Created 4 Jul 2024, 21:42:18 UTC
Sent 5 Jul 2024, 11:35:19 UTC
Report deadline 8 Jul 2024, 11:35:19 UTC
Received 5 Jul 2024, 23:05:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227546
Run time 1 hours 10 min 34 sec
CPU time 47 min 19 sec
Validate state Valid
Credit 46.30
Device peak FLOPS 4.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 9.21 MB
Peak swap size 32.86 GB
Peak disk usage 2.47 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_8000-conf_627.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_8000-conf_627_1_r1549345465_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Schmidt_8000-conf_627_1_r1549345465_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.408928
     * GNaL_b in INaL: 0.005725
     * Gto_b in Ito: 0.083851
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031754
     * GKs_b in IKs: 0.001926
     * GK1_b in IK1: 0.162733
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.580639
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033672
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 375.000000
     * CL_0 in membrane: 8000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1496000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 15413241, states[0] = -84.098744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 30166409, states[0] = -83.979839, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50863842, states[0] = -83.897487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 68494113, states[0] = -83.863867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 85720694, states[0] = -83.863367, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102919302, states[0] = -83.837672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 117789806, states[0] = -83.844886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 135100025, states[0] = -83.825818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 149252039, states[0] = -83.854722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 165312508, states[0] = -83.850156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 183048081, states[0] = -83.819791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 199375910, states[0] = -83.817557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 213707020, states[0] = -83.834385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 232904906, states[0] = -83.865039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 251745741, states[0] = -83.815132, states[40]= 0.000001
Saving checkpoint... 
Iteration: 270429012, states[0] = -83.821547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 287358114, states[0] = -83.815839, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302615518, states[0] = -83.819663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 317479571, states[0] = -83.839652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334978114, states[0] = -83.817207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 351894227, states[0] = -83.814207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 366825622, states[0] = -83.817985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 380463583, states[0] = -83.797671, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394848983, states[0] = -83.817789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413268678, states[0] = -83.847429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 429560182, states[0] = -83.836836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 447791358, states[0] = -83.814243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 467155074, states[0] = -83.816138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 480033314, states[0] = 28.813561, states[40]= 0.000044
Saving checkpoint... 
Iteration: 489315521, states[0] = -83.845375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495085878, states[0] = -83.816401, states[40]= 0.000001
Saving checkpoint... 
Iteration: 500617404, states[0] = -83.856985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 506461430, states[0] = -83.820578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513275974, states[0] = -83.846976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524842584, states[0] = -83.865889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 540436477, states[0] = -83.774620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 559678891, states[0] = -83.814340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577000926, states[0] = -83.859590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 590054414, states[0] = -83.825548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 600372912, states[0] = -83.691394, states[40]= 0.000001
Saving checkpoint... 
Iteration: 609790441, states[0] = -83.830552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 626031821, states[0] = -83.825866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642842248, states[0] = -83.817477, states[40]= 0.000001
Saving checkpoint... 
Iteration: 658238094, states[0] = -83.822836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 669443495, states[0] = -83.840305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 678499565, states[0] = -83.819987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692238553, states[0] = -83.222243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711177314, states[0] = -83.815712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 729891979, states[0] = -83.828249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 745778459, states[0] = -83.830640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 766959186, states[0] = -83.816650, states[40]= 0.000001
Saving checkpoint... 
Iteration: 788102270, states[0] = 3.062841, states[40]= 0.001110
Saving checkpoint... 
Iteration: 809155578, states[0] = -83.851930, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831420597, states[0] = -83.814677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 851303871, states[0] = -83.815039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 869833204, states[0] = -83.829264, states[40]= 0.000001
Saving checkpoint... 
Iteration: 890109496, states[0] = -83.824291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909190399, states[0] = -83.850193, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931102947, states[0] = -83.815732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 949324666, states[0] = -83.844384, states[40]= 0.000001
Saving checkpoint... 
Iteration: 967682679, states[0] = -83.813778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 986558502, states[0] = -83.819051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006875988, states[0] = -83.816785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1028724105, states[0] = -83.865475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046626913, states[0] = -83.818412, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065311661, states[0] = -83.844753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084457200, states[0] = -83.791835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1102427231, states[0] = -83.820104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1121342674, states[0] = -83.843438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136962657, states[0] = -83.860591, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1150058963, states[0] = -83.824717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1165391660, states[0] = -83.841505, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1178056435, states[0] = -83.824720, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193894576, states[0] = -83.827570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1207221981, states[0] = -83.814862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1217875874, states[0] = -83.827910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230724464, states[0] = -83.817444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246373853, states[0] = -83.820460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1265505894, states[0] = -83.837400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280004162, states[0] = 29.833896, states[40]= 0.407481
Saving checkpoint... 
Iteration: 1292717505, states[0] = -83.864899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1307268695, states[0] = -83.814549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321439930, states[0] = -83.839550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1338048415, states[0] = -83.824632, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351307328, states[0] = -83.814350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1364423393, states[0] = -83.760230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1379137254, states[0] = -83.814975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1396131212, states[0] = -17.060185, states[40]= 0.000744
Saving checkpoint... 
Iteration: 1417270695, states[0] = -83.845979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1431088839, states[0] = -83.815118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1442028123, states[0] = -83.824823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1454954244, states[0] = -83.815744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1470214634, states[0] = -83.822039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1490167997, states[0] = -83.822638, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.688396
 - CaMKt in component CaMK (millimolar): 0.000865
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 6.078910
 - nass in component intracellular_ions (millimolar): 6.079017
 - ki in component intracellular_ions (millimolar): 145.825813
 - kss in component intracellular_ions (millimolar): 145.825804
 - cansr in component intracellular_ions (millimolar): 1.647048
 - cajsr in component intracellular_ions (millimolar): 1.647049
 - cai in component intracellular_ions (millimolar): 0.000095
 - m in component INa (dimensionless): 0.011184
 - hf in component INa (dimensionless): 0.537410
 - hs in component INa (dimensionless): 0.537410
 - j in component INa (dimensionless): 0.537411
 - hsp in component INa (dimensionless): 0.295502
 - jp in component INa (dimensionless): 0.537411
 - mL in component INaL (dimensionless): 0.000417
 - hL in component INaL (dimensionless): 0.375866
 - hLp in component INaL (dimensionless): 0.208325
 - a in component Ito (dimensionless): 0.001328
 - iF in component Ito (dimensionless): 0.999072
 - iS in component Ito (dimensionless): 0.998872
 - ap in component Ito (dimensionless): 0.000677
 - iFp in component Ito (dimensionless): 0.999072
 - iSp in component Ito (dimensionless): 0.998992
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999938
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003640
 - xrf in component IKr (dimensionless): 0.000015
 - xrs in component IKr (dimensionless): 0.001023
 - xs1 in component IKs (dimensionless): 0.005952
 - xs2 in component IKs (dimensionless): 0.000308
 - xk1 in component IK1 (dimensionless): 0.996991
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
18:19:06 (4233): called boinc_finish(0)

</stderr_txt>
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