𝕏

Task 56222078

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_726_1
Workunit 26702570
Created 4 Jul 2024, 21:41:41 UTC
Sent 5 Jul 2024, 11:22:09 UTC
Report deadline 8 Jul 2024, 11:22:09 UTC
Received 5 Jul 2024, 21:32:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230398
Run time 2 hours 6 min 13 sec
CPU time 2 hours 4 min 55 sec
Validate state Valid
Credit 44.49
Device peak FLOPS 3.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.79 MB
Peak swap size 4.10 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_726.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_726_1_r1240944084_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_726_1_r1240944084_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.798033
     * GNaL_b in INaL: 0.005909
     * Gto_b in Ito: 0.083615
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031952
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.163597
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.450674
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033619
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11877475, states[0] = 1.932714, states[40]= 0.006084
Saving checkpoint... 
Iteration: 23879103, states[0] = -0.550251, states[40]= 0.005796
Saving checkpoint... 
Iteration: 35870567, states[0] = 5.782834, states[40]= 0.006973
Saving checkpoint... 
Iteration: 47843714, states[0] = 20.642479, states[40]= 0.018795
Saving checkpoint... 
Iteration: 60065219, states[0] = -31.209775, states[40]= 0.000458
Saving checkpoint... 
Iteration: 72341103, states[0] = 20.683877, states[40]= 0.019164
Saving checkpoint... 
Iteration: 84589618, states[0] = -70.797082, states[40]= 0.000002
Saving checkpoint... 
Iteration: 96869562, states[0] = 1.380768, states[40]= 0.006305
Saving checkpoint... 
Iteration: 109100096, states[0] = -86.541863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121293851, states[0] = -87.743160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133515014, states[0] = 14.107120, states[40]= 0.008395
Saving checkpoint... 
Iteration: 145762638, states[0] = -86.391503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157979167, states[0] = -87.816612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170164475, states[0] = 20.735119, states[40]= 0.019637
Saving checkpoint... 
Iteration: 182480835, states[0] = -87.827798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194413995, states[0] = -74.475984, states[40]= 0.000001
Saving checkpoint... 
Iteration: 206678345, states[0] = 11.647756, states[40]= 0.007860
Saving checkpoint... 
Iteration: 218962255, states[0] = -87.784146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231285427, states[0] = -87.753315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243587876, states[0] = -86.890029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255843678, states[0] = 9.250163, states[40]= 0.007488
Saving checkpoint... 
Iteration: 268162671, states[0] = 17.156992, states[40]= 0.009840
Saving checkpoint... 
Iteration: 280430465, states[0] = -87.672180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292732108, states[0] = -65.240444, states[40]= 0.000004
Saving checkpoint... 
Iteration: 304989181, states[0] = 18.677571, states[40]= 0.011714
Saving checkpoint... 
Iteration: 317060725, states[0] = -61.595407, states[40]= 0.000006
Saving checkpoint... 
Iteration: 329190983, states[0] = -11.661713, states[40]= 0.002830
Saving checkpoint... 
Iteration: 341258840, states[0] = -87.680950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353346402, states[0] = -1.026467, states[40]= 0.005804
Saving checkpoint... 
Iteration: 365398130, states[0] = -76.618854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 377523141, states[0] = -16.813780, states[40]= 0.001716
Saving checkpoint... 
Iteration: 389625801, states[0] = -87.824962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401841142, states[0] = -0.617146, states[40]= 0.005896
Saving checkpoint... 
Iteration: 413901883, states[0] = -86.151313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425987793, states[0] = 12.877699, states[40]= 0.008097
Saving checkpoint... 
Iteration: 438087164, states[0] = -87.707983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450164980, states[0] = 3.614559, states[40]= 0.006692
Saving checkpoint... 
Iteration: 462233462, states[0] = -87.050862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474318914, states[0] = 11.214239, states[40]= 0.007786
Saving checkpoint... 
Iteration: 486425697, states[0] = -87.749725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498571504, states[0] = -87.624865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510677191, states[0] = -17.811408, states[40]= 0.001557
Saving checkpoint... 
Iteration: 522836749, states[0] = -9.576243, states[40]= 0.003406
Saving checkpoint... 
Iteration: 534916406, states[0] = -87.732463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547050886, states[0] = -82.866476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559160463, states[0] = -2.381301, states[40]= 0.005476
Saving checkpoint... 
Iteration: 571245013, states[0] = -87.727997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583355559, states[0] = -44.334869, states[40]= 0.000087
Saving checkpoint... 
Iteration: 595422516, states[0] = -87.776899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607450720, states[0] = 22.054887, states[40]= 0.034929
Saving checkpoint... 
Iteration: 619429825, states[0] = -87.807119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631572753, states[0] = -87.729704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643650804, states[0] = -1.129439, states[40]= 0.005780
Saving checkpoint... 
Iteration: 655760793, states[0] = -87.810718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667887224, states[0] = -87.611517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679951631, states[0] = 18.700625, states[40]= 0.011756
Saving checkpoint... 
Iteration: 692067857, states[0] = -87.734294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704097392, states[0] = 41.538639, states[40]= 0.035526
Saving checkpoint... 
Iteration: 716168094, states[0] = -33.927760, states[40]= 0.000341
Saving checkpoint... 
Iteration: 728229658, states[0] = -87.729128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740319270, states[0] = -15.501619, states[40]= 0.001952
Saving checkpoint... 
Iteration: 752447405, states[0] = 17.240853, states[40]= 0.009911
Saving checkpoint... 
Iteration: 764577798, states[0] = -87.794330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776669368, states[0] = -44.063900, states[40]= 0.000091
Saving checkpoint... 
Iteration: 788799014, states[0] = 2.559818, states[40]= 0.006519
Saving checkpoint... 
Iteration: 800910515, states[0] = -87.803392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813076468, states[0] = -87.804858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825145184, states[0] = -17.016220, states[40]= 0.001682
Saving checkpoint... 
Iteration: 837348240, states[0] = -71.917444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849356908, states[0] = -85.403206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861500828, states[0] = -53.448826, states[40]= 0.000023
Saving checkpoint... 
Iteration: 873725288, states[0] = -87.767171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885878820, states[0] = -87.721584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897949393, states[0] = 6.892097, states[40]= 0.007166
Saving checkpoint... 
Iteration: 910122936, states[0] = 0.071291, states[40]= 0.006046
Saving checkpoint... 
Iteration: 922236974, states[0] = -87.818232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934343414, states[0] = -80.132123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946417056, states[0] = 21.958462, states[40]= 0.033374


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_726.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_726_1_r1240944084_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_333-conf_726_1_r1240944084_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.798033
     * GNaL_b in INaL: 0.005909
     * Gto_b in Ito: 0.083615
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031952
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.163597
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.450674
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033619
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 946417056
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 21.958462 (After loading)
 - states[40]: 0.033374 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 958606436, states[0] = 9.453102, states[40]= 0.007517
Saving checkpoint... 
Iteration: 970895790, states[0] = -87.809794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983265871, states[0] = 12.581618, states[40]= 0.008035
Saving checkpoint... 
Iteration: 995500814, states[0] = -74.943944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1007781949, states[0] = -2.047249, states[40]= 0.005559
Saving checkpoint... 
Iteration: 1019892815, states[0] = -87.815173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032157305, states[0] = -63.854175, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1044465239, states[0] = -29.265719, states[40]= 0.000557
Saving checkpoint... 
Iteration: 1056741682, states[0] = 21.044711, states[40]= 0.022155
Saving checkpoint... 
Iteration: 1069044982, states[0] = -87.786603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081258407, states[0] = 11.088590, states[40]= 0.007765
Saving checkpoint... 
Iteration: 1093573776, states[0] = 20.071027, states[40]= 0.015800
Saving checkpoint... 
Iteration: 1105862367, states[0] = -87.743857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118096681, states[0] = 4.843032, states[40]= 0.006879
Saving checkpoint... 
Iteration: 1130512415, states[0] = -87.673621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142644080, states[0] = -60.447596, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1154800371, states[0] = -47.087431, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1167141200, states[0] = -59.782552, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1179330967, states[0] = -87.378548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191570023, states[0] = 17.307209, states[40]= 0.009968
Saving checkpoint... 
Iteration: 1203780669, states[0] = -26.504072, states[40]= 0.000717
Saving checkpoint... 
Iteration: 1216085181, states[0] = 6.179169, states[40]= 0.007068
Saving checkpoint... 
Iteration: 1228364776, states[0] = -87.793900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240665107, states[0] = -87.642182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252979659, states[0] = -82.111274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265184916, states[0] = -87.762478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277457834, states[0] = -51.441145, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1289682132, states[0] = -87.761255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301939673, states[0] = -29.524975, states[40]= 0.000543
Saving checkpoint... 
Iteration: 1314231817, states[0] = 13.169634, states[40]= 0.008161
Saving checkpoint... 
Iteration: 1326435931, states[0] = -27.718310, states[40]= 0.000643
Saving checkpoint... 
Iteration: 1338753864, states[0] = -7.891360, states[40]= 0.003902
Saving checkpoint... 
Iteration: 1351009513, states[0] = -87.761826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363324767, states[0] = -87.689500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375638995, states[0] = -86.133193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387884243, states[0] = 17.043108, states[40]= 0.009751
Saving checkpoint... 
Iteration: 1400148946, states[0] = -87.638894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412460414, states[0] = -77.179353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1424705291, states[0] = 20.885382, states[40]= 0.020791
Saving checkpoint... 
Iteration: 1436952189, states[0] = -67.186114, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1449284427, states[0] = -67.417460, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1461508452, states[0] = -87.794517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473821882, states[0] = -87.728656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486114555, states[0] = -68.224259, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1498298952, states[0] = -87.367611, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.704140
 - CaMKt in component CaMK (millimolar): 0.041829
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 6.999774
 - nass in component intracellular_ions (millimolar): 6.999922
 - ki in component intracellular_ions (millimolar): 144.922123
 - kss in component intracellular_ions (millimolar): 144.922091
 - cansr in component intracellular_ions (millimolar): 1.613318
 - cajsr in component intracellular_ions (millimolar): 1.184226
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.007473
 - hf in component INa (dimensionless): 0.692066
 - hs in component INa (dimensionless): 0.691830
 - j in component INa (dimensionless): 0.681366
 - hsp in component INa (dimensionless): 0.446892
 - jp in component INa (dimensionless): 0.654965
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.293369
 - hLp in component INaL (dimensionless): 0.136389
 - a in component Ito (dimensionless): 0.001013
 - iF in component Ito (dimensionless): 0.999540
 - iS in component Ito (dimensionless): 0.175888
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999540
 - iSp in component Ito (dimensionless): 0.212821
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.803793
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966729
 - jca in component ICaL (dimensionless): 0.948055
 - ffp in component ICaL (dimensionless): 0.999865
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009403
 - xrf in component IKr (dimensionless): 0.028713
 - xrs in component IKr (dimensionless): 0.788609
 - xs1 in component IKs (dimensionless): 0.458838
 - xs2 in component IKs (dimensionless): 0.001180
 - xk1 in component IK1 (dimensionless): 0.996810
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:18:33 (92099): called boinc_finish(0)

</stderr_txt>
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