𝕏

Task 56220574

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_1000-conf_525_1
Workunit 26701818
Created 4 Jul 2024, 21:41:04 UTC
Sent 5 Jul 2024, 11:15:07 UTC
Report deadline 8 Jul 2024, 11:15:07 UTC
Received 6 Jul 2024, 15:24:24 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215304
Run time 56 min 46 sec
CPU time 55 min 17 sec
Validate state Valid
Credit 45.55
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.78 MB
Peak swap size 6.24 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.20</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_1000-conf_525.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_1000-conf_525_1_r1227227004_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_ENDO_1000-conf_525_1_r1227227004_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 102.656651
     * GNaL_b in INaL: 0.005747
     * Gto_b in Ito: 0.084153
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031907
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.164035
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.449280
     * GKb_b in IKb: 0.003796
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032355
     * celltype in environment: 0.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8436913, states[0] = -94.436000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16324636, states[0] = -94.290429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24089697, states[0] = 3.907049, states[40]= 0.003188
Saving checkpoint... 
Iteration: 31866883, states[0] = -94.331030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39563391, states[0] = 16.554389, states[40]= 0.000858
Saving checkpoint... 
Iteration: 48582913, states[0] = 7.219785, states[40]= 0.002261
Saving checkpoint... 
Iteration: 56989169, states[0] = -94.414261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65695585, states[0] = -93.632100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74089961, states[0] = 3.086402, states[40]= 0.002820
Saving checkpoint... 
Iteration: 81926821, states[0] = -94.396593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89711345, states[0] = -93.902943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98070785, states[0] = 12.914909, states[40]= 0.001206
Saving checkpoint... 
Iteration: 106722535, states[0] = -93.967519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115522399, states[0] = 31.676345, states[40]= 0.000869
Saving checkpoint... 
Iteration: 124578525, states[0] = 9.147267, states[40]= 0.001786
Saving checkpoint... 
Iteration: 133459147, states[0] = -94.416393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141209926, states[0] = -93.897792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150182849, states[0] = -89.361830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158967618, states[0] = -94.419960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167834826, states[0] = -94.313316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176674223, states[0] = -77.573494, states[40]= 0.000002
Saving checkpoint... 
Iteration: 185527011, states[0] = 30.503037, states[40]= 0.000232
Saving checkpoint... 
Iteration: 194356015, states[0] = -94.342156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203335466, states[0] = -94.314217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212105956, states[0] = -9.257399, states[40]= 0.002411
Saving checkpoint... 
Iteration: 221129680, states[0] = -31.768213, states[40]= 0.001305
Saving checkpoint... 
Iteration: 230710882, states[0] = -93.903817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240247257, states[0] = -94.084618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249116318, states[0] = -19.371618, states[40]= 0.001365
Saving checkpoint... 
Iteration: 257769496, states[0] = -94.165301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266570429, states[0] = 13.021516, states[40]= 0.001170
Saving checkpoint... 
Iteration: 275622814, states[0] = -25.485237, states[40]= 0.001498
Saving checkpoint... 
Iteration: 284797199, states[0] = -94.241017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293677996, states[0] = -83.235552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302343370, states[0] = -94.324811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311046668, states[0] = 23.382963, states[40]= 0.000262
Saving checkpoint... 
Iteration: 319864181, states[0] = -94.350490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328566929, states[0] = 14.635574, states[40]= 0.000959
Saving checkpoint... 
Iteration: 337236978, states[0] = -94.039077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346967878, states[0] = -94.418686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356214940, states[0] = -93.926505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366031573, states[0] = 29.082998, states[40]= 0.000126
Saving checkpoint... 
Iteration: 375232021, states[0] = -94.015436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384544158, states[0] = 24.397930, states[40]= 0.000221
Saving checkpoint... 
Iteration: 393384555, states[0] = -94.369934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402142718, states[0] = -43.845446, states[40]= 0.000398
Saving checkpoint... 
Iteration: 411159385, states[0] = -60.049632, states[40]= 0.000039
Saving checkpoint... 
Iteration: 420169652, states[0] = -71.385863, states[40]= 0.000006
Saving checkpoint... 
Iteration: 428875456, states[0] = -94.361100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437707895, states[0] = -93.882248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446526585, states[0] = 30.622516, states[40]= 0.000257
Saving checkpoint... 
Iteration: 455054812, states[0] = 19.979034, states[40]= 0.000452
Saving checkpoint... 
Iteration: 463784245, states[0] = -94.206608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473454913, states[0] = -94.412496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482489545, states[0] = -94.423970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491218076, states[0] = -93.942594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499907800, states[0] = -94.387010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508520807, states[0] = 31.972347, states[40]= 0.001470
Saving checkpoint... 
Iteration: 517573982, states[0] = 11.343238, states[40]= 0.001418
Saving checkpoint... 
Iteration: 526584181, states[0] = 6.182981, states[40]= 0.002278
Saving checkpoint... 
Iteration: 535641812, states[0] = -42.985654, states[40]= 0.000442
Saving checkpoint... 
Iteration: 544849373, states[0] = -94.330386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554019763, states[0] = 32.144191, states[40]= 0.002091
Saving checkpoint... 
Iteration: 563160552, states[0] = -61.228566, states[40]= 0.000033
Saving checkpoint... 
Iteration: 572253536, states[0] = -94.106083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580535782, states[0] = 27.613860, states[40]= 0.000131
Saving checkpoint... 
Iteration: 589904365, states[0] = -94.383679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599357201, states[0] = -94.339584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608932477, states[0] = -94.400728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619153549, states[0] = -54.285783, states[40]= 0.000095
Saving checkpoint... 
Iteration: 629795020, states[0] = -94.232297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639102714, states[0] = -6.313120, states[40]= 0.002820
Saving checkpoint... 
Iteration: 649244405, states[0] = -94.068493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658581969, states[0] = 7.358437, states[40]= 0.002079
Saving checkpoint... 
Iteration: 667722444, states[0] = -93.964180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676863497, states[0] = -94.346048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686614491, states[0] = -17.591920, states[40]= 0.001420
Saving checkpoint... 
Iteration: 696661996, states[0] = -62.712092, states[40]= 0.000026
Saving checkpoint... 
Iteration: 706625624, states[0] = -28.060093, states[40]= 0.001498
Saving checkpoint... 
Iteration: 716317853, states[0] = -94.279513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725747251, states[0] = -94.079552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734888274, states[0] = -94.369639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744084929, states[0] = 5.778056, states[40]= 0.002346
Saving checkpoint... 
Iteration: 753718708, states[0] = -93.943281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763200300, states[0] = -93.801959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772442344, states[0] = -94.403931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781829469, states[0] = -94.298959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791516548, states[0] = 32.478338, states[40]= 0.006309
Saving checkpoint... 
Iteration: 801489651, states[0] = -94.420718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810712749, states[0] = -93.909008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821531098, states[0] = 29.241768, states[40]= 0.000129
Saving checkpoint... 
Iteration: 831242045, states[0] = -94.056472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840756392, states[0] = -94.114041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849996281, states[0] = -94.421933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859233396, states[0] = -94.016914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868504922, states[0] = 33.711504, states[40]= 0.357231
Saving checkpoint... 
Iteration: 878864528, states[0] = -94.345105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889163183, states[0] = -63.954264, states[40]= 0.000021
Saving checkpoint... 
Iteration: 899127734, states[0] = -29.986394, states[40]= 0.001422
Saving checkpoint... 
Iteration: 908733257, states[0] = -94.015734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918142094, states[0] = -43.246913, states[40]= 0.000428
Saving checkpoint... 
Iteration: 927316362, states[0] = -94.274549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936588611, states[0] = 3.700732, states[40]= 0.002667
Saving checkpoint... 
Iteration: 946610719, states[0] = -13.872530, states[40]= 0.001746
Saving checkpoint... 
Iteration: 956478277, states[0] = -94.415839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966267550, states[0] = -94.151639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975621353, states[0] = -24.126054, states[40]= 0.001462
Saving checkpoint... 
Iteration: 984729510, states[0] = -93.996813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993922544, states[0] = -94.391271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003513417, states[0] = 32.444376, states[40]= 0.018704
Saving checkpoint... 
Iteration: 1013922741, states[0] = -94.391180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023637575, states[0] = -39.012901, states[40]= 0.000698
Saving checkpoint... 
Iteration: 1033269557, states[0] = -94.157432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042670218, states[0] = -72.085134, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1052000482, states[0] = -28.242726, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1061271143, states[0] = -94.162167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071447229, states[0] = -94.403081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081460624, states[0] = -94.408485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091376939, states[0] = -94.355703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101195029, states[0] = -93.636545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110363510, states[0] = -94.341587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119888727, states[0] = -94.366054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129268971, states[0] = -94.154550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138511288, states[0] = 32.191213, states[40]= 0.039244
Saving checkpoint... 
Iteration: 1147145011, states[0] = -46.020420, states[40]= 0.000302
Saving checkpoint... 
Iteration: 1156262698, states[0] = -94.133335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165046648, states[0] = 23.393829, states[40]= 0.000262
Saving checkpoint... 
Iteration: 1174185200, states[0] = -91.244474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183598826, states[0] = -3.111412, states[40]= 0.003080
Saving checkpoint... 
Iteration: 1191643575, states[0] = -44.648696, states[40]= 0.000360
Saving checkpoint... 
Iteration: 1199552654, states[0] = 20.898551, states[40]= 0.000392
Saving checkpoint... 
Iteration: 1208168288, states[0] = -69.685430, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1216202255, states[0] = -93.824334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223516251, states[0] = 32.493160, states[40]= 0.006991
Saving checkpoint... 
Iteration: 1231085640, states[0] = 5.390286, states[40]= 0.002410
Saving checkpoint... 
Iteration: 1238487823, states[0] = -94.415727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246188136, states[0] = -92.599673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254819837, states[0] = -94.277559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262140434, states[0] = -41.677528, states[40]= 0.000516
Saving checkpoint... 
Iteration: 1269613768, states[0] = -16.876062, states[40]= 0.001461
Saving checkpoint... 
Iteration: 1277200857, states[0] = -93.805054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284488977, states[0] = -94.415569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293013862, states[0] = 32.475024, states[40]= 0.016021
Saving checkpoint... 
Iteration: 1301122529, states[0] = -25.210704, states[40]= 0.001492
Saving checkpoint... 
Iteration: 1309370159, states[0] = -94.346680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317778828, states[0] = -94.182606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325120593, states[0] = -23.414577, states[40]= 0.001438
Saving checkpoint... 
Iteration: 1332845604, states[0] = -94.317232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339977067, states[0] = -94.411518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347031983, states[0] = 28.948805, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1354461382, states[0] = -94.405964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362273317, states[0] = -94.165773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369778143, states[0] = -94.180085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376973038, states[0] = -94.409843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384684243, states[0] = -90.573150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392152526, states[0] = -53.276680, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1399259767, states[0] = -94.120494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406246026, states[0] = -94.067361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413802577, states[0] = -94.241477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421450217, states[0] = -94.400782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429187690, states[0] = -92.444698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437398525, states[0] = -94.370644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445471532, states[0] = -94.408638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453770649, states[0] = -94.156517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461371676, states[0] = -94.346671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469225014, states[0] = -93.969097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477026220, states[0] = 30.727196, states[40]= 0.000281
Saving checkpoint... 
Iteration: 1484910128, states[0] = -94.378441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492891218, states[0] = -94.364287, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.292027
 - CaMKt in component CaMK (millimolar): 0.017800
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.028416
 - nass in component intracellular_ions (millimolar): 7.028540
 - ki in component intracellular_ions (millimolar): 144.748632
 - kss in component intracellular_ions (millimolar): 144.748613
 - cansr in component intracellular_ions (millimolar): 1.944943
 - cajsr in component intracellular_ions (millimolar): 1.900496
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003848
 - hf in component INa (dimensionless): 0.869010
 - hs in component INa (dimensionless): 0.869000
 - j in component INa (dimensionless): 0.868932
 - hsp in component INa (dimensionless): 0.705414
 - jp in component INa (dimensionless): 0.868884
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.687422
 - hLp in component INaL (dimensionless): 0.417710
 - a in component Ito (dimensionless): 0.000650
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.596153
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.662355
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.899918
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999756
 - jca in component ICaL (dimensionless): 0.999965
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004613
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.398038
 - xs1 in component IKs (dimensionless): 0.291894
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997493
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:41:21 (6456): called boinc_finish(0)

</stderr_txt>
]]>


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