𝕏

Task 56218863

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223_0
Workunit 26700964
Created 4 Jul 2024, 21:40:22 UTC
Sent 5 Jul 2024, 11:03:16 UTC
Report deadline 8 Jul 2024, 11:03:16 UTC
Received 5 Jul 2024, 18:01:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241303
Run time 1 hours 48 min 19 sec
CPU time 1 hours 43 min 48 sec
Validate state Valid
Credit 43.62
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.15 MB
Peak swap size 6.22 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223_0_r505564653_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223_0_r505564653_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.445961
     * GNaL_b in INaL: 0.005887
     * Gto_b in Ito: 0.085313
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031963
     * GKs_b in IKs: 0.001937
     * GK1_b in IK1: 0.163510
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.428779
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032004
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11309713, states[0] = -87.055068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25903918, states[0] = -87.036047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40351967, states[0] = -86.981292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54573458, states[0] = 0.250375, states[40]= 0.004192
Saving checkpoint... 
Iteration: 68707054, states[0] = -86.787734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82718781, states[0] = -86.801565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97054735, states[0] = 9.798481, states[40]= 0.004712
Saving checkpoint... 
Iteration: 111082150, states[0] = -4.756312, states[40]= 0.003371
Saving checkpoint... 
Iteration: 125041446, states[0] = 15.202826, states[40]= 0.004836
Saving checkpoint... 
Iteration: 139013663, states[0] = 22.769500, states[40]= 0.020150
Saving checkpoint... 
Iteration: 152904312, states[0] = -86.946005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166803802, states[0] = -86.893745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180491753, states[0] = -86.962831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194382486, states[0] = -86.937141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208430202, states[0] = -86.951275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222339901, states[0] = -86.917062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236108052, states[0] = -29.115114, states[40]= 0.000463
Saving checkpoint... 
Iteration: 250063649, states[0] = 6.037049, states[40]= 0.004619
Saving checkpoint... 
Iteration: 263973259, states[0] = -86.959273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277428717, states[0] = -86.950510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291174656, states[0] = -86.678203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305020111, states[0] = 21.867364, states[40]= 0.008296
Saving checkpoint... 
Iteration: 318867863, states[0] = -86.930563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332802047, states[0] = -86.890809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346680122, states[0] = -86.704201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360562638, states[0] = 6.504219, states[40]= 0.004637
Saving checkpoint... 
Iteration: 374522775, states[0] = 21.299139, states[40]= 0.006937
Saving checkpoint... 
Iteration: 388483684, states[0] = -86.960653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402426477, states[0] = -86.949820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416396655, states[0] = -86.941319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430311445, states[0] = -86.898090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444320922, states[0] = -86.904841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457930406, states[0] = -86.950728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471785983, states[0] = -86.876398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485708707, states[0] = -86.765949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499610404, states[0] = -31.461007, states[40]= 0.000363
Saving checkpoint... 
Iteration: 513382467, states[0] = -86.936278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527267999, states[0] = -86.857371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541173975, states[0] = -86.672519, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223_0_r505564653_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223_0_r505564653_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.445961
     * GNaL_b in INaL: 0.005887
     * Gto_b in Ito: 0.085313
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031963
     * GKs_b in IKs: 0.001937
     * GK1_b in IK1: 0.163510
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.428779
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032004
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 541173975
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.672519 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 557116035, states[0] = -37.118132, states[40]= 0.000177
Saving checkpoint... 
Iteration: 572549396, states[0] = 12.135138, states[40]= 0.004737
Saving checkpoint... 
Iteration: 586235544, states[0] = -86.813271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600704578, states[0] = -86.757755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614825580, states[0] = -86.907816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628903931, states[0] = -86.943465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642964322, states[0] = -86.957455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656985047, states[0] = -86.960649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670952888, states[0] = -86.955368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684308230, states[0] = -86.895465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698233426, states[0] = -86.809817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712148342, states[0] = -74.781278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726004758, states[0] = 26.879397, states[40]= 0.150454
Saving checkpoint... 
Iteration: 739931784, states[0] = -86.950850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753856636, states[0] = -86.925125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767863419, states[0] = -86.928267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782055752, states[0] = 9.520090, states[40]= 0.004706
Saving checkpoint... 
Iteration: 795946385, states[0] = -86.953997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809795366, states[0] = -86.884784, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223_0_r505564653_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223_0_r505564653_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.445961
     * GNaL_b in INaL: 0.005887
     * Gto_b in Ito: 0.085313
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031963
     * GKs_b in IKs: 0.001937
     * GK1_b in IK1: 0.163510
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.428779
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032004
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 809795366
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.884784 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 826328218, states[0] = -86.909357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841871354, states[0] = -86.931650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855685027, states[0] = -86.716805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869917665, states[0] = -86.947221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883390466, states[0] = -86.938897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897418169, states[0] = -86.947335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911309155, states[0] = -86.896012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924833418, states[0] = -86.912497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938806295, states[0] = -86.893774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952827987, states[0] = -86.909119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966578247, states[0] = -1.832167, states[40]= 0.003883
Saving checkpoint... 
Iteration: 980478093, states[0] = -86.959415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994430098, states[0] = -86.950270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008323793, states[0] = -86.906361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022291853, states[0] = -86.881494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036199470, states[0] = -86.747181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050199118, states[0] = -86.746456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064133915, states[0] = -56.125700, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1078102704, states[0] = -23.752296, states[40]= 0.000708
Saving checkpoint... 
Iteration: 1092128266, states[0] = -49.870486, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1106090534, states[0] = -11.679764, states[40]= 0.001966
Saving checkpoint... 
Iteration: 1119952377, states[0] = -86.954949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133838217, states[0] = -86.915168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147841454, states[0] = -86.916988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161399180, states[0] = -86.941600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175335865, states[0] = -86.913772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189280244, states[0] = -86.870188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203263888, states[0] = -86.852043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217163218, states[0] = -86.197560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231835703, states[0] = -86.913636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246032972, states[0] = 18.327601, states[40]= 0.005210
Saving checkpoint... 
Iteration: 1260426103, states[0] = -86.949111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273831372, states[0] = -86.911002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288662009, states[0] = -86.009143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302788051, states[0] = -86.877771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316767026, states[0] = -86.855674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330249920, states[0] = -86.833958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344012380, states[0] = 22.909659, states[40]= 0.026319
Saving checkpoint... 
Iteration: 1358000163, states[0] = -66.892532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367472151, states[0] = -86.958224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381935064, states[0] = -86.951145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396005251, states[0] = 25.987703, states[40]= 0.138679
Saving checkpoint... 
Iteration: 1409927131, states[0] = -86.949257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423339956, states[0] = -86.915950, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223_0_r505564653_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Pieske_1000-conf_223_0_r505564653_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.445961
     * GNaL_b in INaL: 0.005887
     * Gto_b in Ito: 0.085313
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031963
     * GKs_b in IKs: 0.001937
     * GK1_b in IK1: 0.163510
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.428779
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032004
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1423339956
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.915950 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1439108063, states[0] = -29.116306, states[40]= 0.000463
Saving checkpoint... 
Iteration: 1454282912, states[0] = -86.872684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468753778, states[0] = -86.839076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483322633, states[0] = -86.905248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497650254, states[0] = -77.455363, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.837855
 - CaMKt in component CaMK (millimolar): 0.006777
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.405633
 - nass in component intracellular_ions (millimolar): 6.405690
 - ki in component intracellular_ions (millimolar): 145.577923
 - kss in component intracellular_ions (millimolar): 145.577904
 - cansr in component intracellular_ions (millimolar): 1.294613
 - cajsr in component intracellular_ions (millimolar): 1.256812
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008153
 - hf in component INa (dimensionless): 0.660927
 - hs in component INa (dimensionless): 0.660916
 - j in component INa (dimensionless): 0.660852
 - hsp in component INa (dimensionless): 0.413027
 - jp in component INa (dimensionless): 0.660808
 - mL in component INaL (dimensionless): 0.000229
 - hL in component INaL (dimensionless): 0.465992
 - hLp in component INaL (dimensionless): 0.240712
 - a in component Ito (dimensionless): 0.001074
 - iF in component Ito (dimensionless): 0.999465
 - iS in component Ito (dimensionless): 0.578459
 - ap in component Ito (dimensionless): 0.000547
 - iFp in component Ito (dimensionless): 0.999465
 - iSp in component Ito (dimensionless): 0.632981
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935257
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999893
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001530
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.405974
 - xs1 in component IKs (dimensionless): 0.242329
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997022
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:54:02 (5736): called boinc_finish(0)

</stderr_txt>
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