𝕏

Task 56200932

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_1000-conf_306_0
Workunit 26692009
Created 4 Jul 2024, 21:32:21 UTC
Sent 5 Jul 2024, 9:26:57 UTC
Report deadline 8 Jul 2024, 9:26:57 UTC
Received 6 Jul 2024, 10:54:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220836
Run time 39 min 28 sec
CPU time 33 min 11 sec
Validate state Valid
Credit 43.64
Device peak FLOPS 5.24 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.50 MB
Peak swap size 391.88 GB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_1000-conf_306.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_1000-conf_306_0_r879855087_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_1000-conf_306_0_r879855087_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 102.809292
     * GNaL_b in INaL: 0.005835
     * Gto_b in Ito: 0.083854
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031862
     * GKs_b in IKs: 0.001920
     * GK1_b in IK1: 0.163070
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.211613
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033732
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 4616353, states[0] = -11.695900, states[40]= 0.000219
Saving checkpoint... 
Iteration: 8933244, states[0] = -94.617059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 12498311, states[0] = -94.614156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17230453, states[0] = -94.253337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21783037, states[0] = -94.429383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26147079, states[0] = -60.202015, states[40]= 0.000054
Saving checkpoint... 
Iteration: 30133944, states[0] = -44.353621, states[40]= 0.000424
Saving checkpoint... 
Iteration: 34939186, states[0] = -94.596444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38097598, states[0] = -3.182355, states[40]= 0.000886
Saving checkpoint... 
Iteration: 43002225, states[0] = 23.085474, states[40]= 2.515089
Saving checkpoint... 
Iteration: 47821068, states[0] = -94.531228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52336369, states[0] = -94.558429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57014702, states[0] = 21.916796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62085718, states[0] = 4.449496, states[40]= 0.000579
Saving checkpoint... 
Iteration: 67097254, states[0] = -5.506758, states[40]= 0.001551
Saving checkpoint... 
Iteration: 70977885, states[0] = -94.652568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73983106, states[0] = -94.655802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76702120, states[0] = -94.114072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79541184, states[0] = 22.641742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84325766, states[0] = -94.578033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87533197, states[0] = 23.487423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91681125, states[0] = -93.931411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94709249, states[0] = -94.178209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97353100, states[0] = -94.615823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100333311, states[0] = -94.595531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103534267, states[0] = 23.345693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107916836, states[0] = -94.658426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112166776, states[0] = -93.355679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116747020, states[0] = -94.392905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121422818, states[0] = -94.663052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125895488, states[0] = -94.652167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130309249, states[0] = -94.566075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133540562, states[0] = 22.520174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135542189, states[0] = 22.233892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 139962718, states[0] = -94.674101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144865124, states[0] = -94.633733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149141463, states[0] = -61.673626, states[40]= 0.000148
Saving checkpoint... 
Iteration: 153580355, states[0] = 6.806783, states[40]= 0.000474
Saving checkpoint... 
Iteration: 158247812, states[0] = -94.398554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162571039, states[0] = 12.030521, states[40]= 0.000131
Saving checkpoint... 
Iteration: 167402398, states[0] = -94.656274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171868731, states[0] = -94.636048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176162977, states[0] = -92.408690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180573329, states[0] = 10.830855, states[40]= 0.000183
Saving checkpoint... 
Iteration: 185419287, states[0] = -94.662255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190238759, states[0] = -94.357459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195024261, states[0] = 23.289281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199640690, states[0] = -60.803787, states[40]= 0.000168
Saving checkpoint... 
Iteration: 202537722, states[0] = 22.895429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205913431, states[0] = -94.658782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209407381, states[0] = -94.656085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213029006, states[0] = 23.461524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217790996, states[0] = -94.527686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222383183, states[0] = -94.642718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226634699, states[0] = -53.198459, states[40]= 0.000442
Saving checkpoint... 
Iteration: 231309835, states[0] = -94.563476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235897882, states[0] = -94.649752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238769197, states[0] = -94.469332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243592684, states[0] = -2.691049, states[40]= 0.001672
Saving checkpoint... 
Iteration: 246396243, states[0] = -94.648097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250461032, states[0] = -94.668092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254516443, states[0] = 22.160458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259197636, states[0] = -94.090507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263617219, states[0] = -31.452565, states[40]= 0.002399
Saving checkpoint... 
Iteration: 267108809, states[0] = -21.385884, states[40]= 0.001748
Saving checkpoint... 
Iteration: 270499725, states[0] = -94.670688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275422550, states[0] = -94.656692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280376999, states[0] = -94.634158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284901584, states[0] = -94.647591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289157701, states[0] = -87.635943, states[40]= 0.000003
Saving checkpoint... 
Iteration: 293695147, states[0] = -94.066443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297833047, states[0] = -94.592034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301763967, states[0] = -94.447766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304046830, states[0] = 21.198960, states[40]= 0.000002
Saving checkpoint... 
Iteration: 308536752, states[0] = 23.010526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311852451, states[0] = -94.611952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315728663, states[0] = -94.296732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318056279, states[0] = 18.380919, states[40]= 0.000011
Saving checkpoint... 
Iteration: 322812619, states[0] = -94.560711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327244714, states[0] = -94.373369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331549328, states[0] = 20.555378, states[40]= 0.000003
Saving checkpoint... 
Iteration: 335941416, states[0] = -94.657157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339855015, states[0] = -94.612027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344494297, states[0] = -94.664289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346924052, states[0] = -94.651332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350834405, states[0] = -94.589329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355447741, states[0] = -94.657003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359782686, states[0] = -94.496523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363927365, states[0] = -94.651003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368399513, states[0] = -94.639776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373030575, states[0] = 23.441916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376029998, states[0] = 23.453751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380543851, states[0] = 21.870836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 383849039, states[0] = -94.602723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386763263, states[0] = -94.438389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390555119, states[0] = 18.783652, states[40]= 0.000009
Saving checkpoint... 
Iteration: 393596048, states[0] = -6.099740, states[40]= 0.001912
Saving checkpoint... 
Iteration: 397051790, states[0] = 19.850343, states[40]= 0.000005
Saving checkpoint... 
Iteration: 400004022, states[0] = 12.769671, states[40]= 1.439629
Saving checkpoint... 
Iteration: 403179321, states[0] = -93.901473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407414491, states[0] = -94.643043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411726013, states[0] = -94.274129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416164543, states[0] = -92.949701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 420395764, states[0] = -94.633713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425249908, states[0] = -94.386788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429179872, states[0] = -93.905889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433317827, states[0] = -94.559927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436151839, states[0] = -77.372189, states[40]= 0.000017
Saving checkpoint... 
Iteration: 440289914, states[0] = -94.507108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445077102, states[0] = 8.729363, states[40]= 0.000313
Saving checkpoint... 
Iteration: 447360664, states[0] = -94.608211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450256680, states[0] = -94.410439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454696034, states[0] = -94.060485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459226123, states[0] = -94.270747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463636008, states[0] = -54.841995, states[40]= 0.000361
Saving checkpoint... 
Iteration: 468141946, states[0] = -62.439088, states[40]= 0.000134
Saving checkpoint... 
Iteration: 471969086, states[0] = -94.651280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476523110, states[0] = 23.194791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479427996, states[0] = -94.641760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482100316, states[0] = -10.987312, states[40]= 0.001846
Saving checkpoint... 
Iteration: 485636916, states[0] = -55.988154, states[40]= 0.000313
Saving checkpoint... 
Iteration: 490474457, states[0] = -94.650474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495105535, states[0] = -17.375555, states[40]= 0.001605
Saving checkpoint... 
Iteration: 499679304, states[0] = -93.893028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502665577, states[0] = -93.183730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507351684, states[0] = -94.595176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511187577, states[0] = -93.979105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515994229, states[0] = -94.650284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520807863, states[0] = -94.536324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525888319, states[0] = -94.621021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530019290, states[0] = 22.709046, states[40]= -0.000000
Saving checkpoint... 
Iteration: 532355568, states[0] = -94.596737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535423860, states[0] = -94.635851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539926418, states[0] = -94.636317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542944607, states[0] = -94.640986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546521506, states[0] = 23.023365, states[40]= -0.000000
Saving checkpoint... 
Iteration: 550684284, states[0] = -93.943234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553665787, states[0] = -93.218795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557887905, states[0] = -94.618152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562016431, states[0] = 22.162535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566063510, states[0] = 15.554846, states[40]= 0.000040
Saving checkpoint... 
Iteration: 568714959, states[0] = -94.193511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572308563, states[0] = -94.533298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577322155, states[0] = -94.554465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582014581, states[0] = 21.708643, states[40]= -0.000000
Saving checkpoint... 
Iteration: 586431155, states[0] = -94.633916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591173455, states[0] = -93.789949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593656616, states[0] = -85.878348, states[40]= 0.000005
Saving checkpoint... 
Iteration: 598516073, states[0] = 22.081740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603375634, states[0] = -94.606748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607684818, states[0] = -93.943778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612213446, states[0] = -94.179751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615386642, states[0] = -94.612698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619286489, states[0] = -94.484342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624162393, states[0] = -92.082699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 628964158, states[0] = -94.637674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633106208, states[0] = -18.189307, states[40]= 0.001606
Saving checkpoint... 
Iteration: 637377017, states[0] = -94.604885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641572430, states[0] = 11.302402, states[40]= 0.000161
Saving checkpoint... 
Iteration: 645622950, states[0] = -38.371551, states[40]= 0.001814
Saving checkpoint... 
Iteration: 650393173, states[0] = -94.613468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654677871, states[0] = -93.861488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658467623, states[0] = -94.635778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662520001, states[0] = 22.821949, states[40]= -0.000000
Saving checkpoint... 
Iteration: 666898802, states[0] = -94.614956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671693485, states[0] = -94.019866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675738820, states[0] = -94.317868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678559751, states[0] = 17.103669, states[40]= 0.000021
Saving checkpoint... 
Iteration: 682534483, states[0] = 23.240838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686007677, states[0] = 18.769616, states[40]= -0.000004
Saving checkpoint... 
Iteration: 690664581, states[0] = -92.924278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 694620508, states[0] = -35.384652, states[40]= 0.002139
Saving checkpoint... 
Iteration: 697257651, states[0] = -94.393362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700971737, states[0] = -94.632865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703758992, states[0] = -94.397583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706363073, states[0] = -94.588927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709140018, states[0] = -59.909686, states[40]= 0.000188
Saving checkpoint... 
Iteration: 714023768, states[0] = 23.258161, states[40]= -0.000000
Saving checkpoint... 
Iteration: 718939532, states[0] = -94.625387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723248324, states[0] = -94.355610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727368552, states[0] = -94.591534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731603371, states[0] = -14.690480, states[40]= 0.001659
Saving checkpoint... 
Iteration: 736221158, states[0] = -94.218641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740715825, states[0] = -94.184781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745248815, states[0] = -94.355749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748840728, states[0] = -94.564035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752167820, states[0] = -93.485066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755071719, states[0] = 11.674237, states[40]= 0.000144
Saving checkpoint... 
Iteration: 758531206, states[0] = 23.432878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763099527, states[0] = -10.021186, states[40]= 0.001873
Saving checkpoint... 
Iteration: 766838081, states[0] = -94.559522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769739304, states[0] = -94.312319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773482622, states[0] = -94.628229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777212003, states[0] = -94.156097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780329986, states[0] = -94.548497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784765618, states[0] = -94.413059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787508064, states[0] = 19.050020, states[40]= -0.000004
Saving checkpoint... 
Iteration: 791076475, states[0] = 9.103730, states[40]= 0.000285
Saving checkpoint... 
Iteration: 794985140, states[0] = -94.626706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798434043, states[0] = -94.617410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801005967, states[0] = 16.871089, states[40]= -0.000001
Saving checkpoint... 
Iteration: 805239358, states[0] = -94.309611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809503030, states[0] = 14.504203, states[40]= 2.115537
Saving checkpoint... 
Iteration: 812766095, states[0] = -94.412244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816405869, states[0] = -94.605979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820245573, states[0] = -94.336011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823649462, states[0] = -73.233840, states[40]= 0.000029
Saving checkpoint... 
Iteration: 826782886, states[0] = -94.458452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829665941, states[0] = -93.215903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833627655, states[0] = -44.217881, states[40]= 0.001138
Saving checkpoint... 
Iteration: 837529230, states[0] = 23.472433, states[40]= 0.000000
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Iteration: 841421331, states[0] = -94.609932, states[40]= 0.000000
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Iteration: 845584423, states[0] = 4.075443, states[40]= 0.000777
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Iteration: 849732120, states[0] = -94.270401, states[40]= 0.000000
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Iteration: 853681967, states[0] = -93.893131, states[40]= 0.000000
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Iteration: 857826007, states[0] = -94.536798, states[40]= 0.000000
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Iteration: 861231492, states[0] = -94.266165, states[40]= 0.000000
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Iteration: 865307708, states[0] = -94.507640, states[40]= 0.000000
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Iteration: 868086967, states[0] = 2.208923, states[40]= 0.001025
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Iteration: 871344587, states[0] = -94.558118, states[40]= 0.000000
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Iteration: 874854114, states[0] = -94.567288, states[40]= 0.000000
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Iteration: 878665018, states[0] = -93.014468, states[40]= 0.000000
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Iteration: 882357801, states[0] = -94.569990, states[40]= 0.000000
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Iteration: 886555010, states[0] = 18.836618, states[40]= 0.000009
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Iteration: 890995116, states[0] = -94.619641, states[40]= 0.000000
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Iteration: 894142643, states[0] = -63.304766, states[40]= 0.000118
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Iteration: 897337543, states[0] = -94.548138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899406545, states[0] = -94.599461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903629697, states[0] = -46.795355, states[40]= 0.000887
Saving checkpoint... 
Iteration: 907451572, states[0] = -94.612634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911333311, states[0] = -94.541907, states[40]= 0.000000
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Iteration: 915478436, states[0] = -94.616131, states[40]= 0.000000
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Iteration: 919677908, states[0] = -93.839192, states[40]= 0.000000
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Iteration: 922367960, states[0] = -94.575021, states[40]= 0.000000
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Iteration: 925692965, states[0] = -93.993728, states[40]= 0.000000
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Iteration: 927238337, states[0] = -94.294610, states[40]= 0.000000
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Iteration: 930392565, states[0] = -94.590179, states[40]= 0.000000
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Iteration: 933829247, states[0] = -94.534888, states[40]= 0.000000
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Iteration: 937750103, states[0] = -94.344879, states[40]= 0.000000
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Iteration: 941478082, states[0] = -94.613963, states[40]= 0.000000
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Iteration: 944765332, states[0] = -94.398850, states[40]= 0.000000
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Iteration: 948897626, states[0] = -94.591261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952592208, states[0] = -2.201263, states[40]= 0.001603
Saving checkpoint... 
Iteration: 955739970, states[0] = -94.299861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958957588, states[0] = -94.609563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961681167, states[0] = -93.875084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964144028, states[0] = -65.158035, states[40]= 0.000091
Saving checkpoint... 
Iteration: 966906555, states[0] = -94.593933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969597398, states[0] = -7.541788, states[40]= 0.001914
Saving checkpoint... 
Iteration: 973738035, states[0] = -94.289304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978182589, states[0] = -93.889143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980973747, states[0] = -94.610198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983713097, states[0] = -94.146131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988130300, states[0] = -47.552044, states[40]= 0.000820
Saving checkpoint... 
Iteration: 992217521, states[0] = -94.174528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995564093, states[0] = 15.315589, states[40]= 0.000043
Saving checkpoint... 
Iteration: 998842484, states[0] = -94.545371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002894878, states[0] = -94.585444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007374445, states[0] = -94.572767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011240101, states[0] = -94.295827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015158798, states[0] = -88.924268, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1017934864, states[0] = -94.599622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021372816, states[0] = -94.570500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025520925, states[0] = 22.959561, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1029753665, states[0] = -94.351118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032756592, states[0] = -94.361743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035985584, states[0] = -94.607064, states[40]= 0.000000
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Iteration: 1040205984, states[0] = -94.090745, states[40]= 0.000000
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Iteration: 1044232925, states[0] = -94.258322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047943024, states[0] = -94.599307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051408611, states[0] = -94.587931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054713516, states[0] = -94.143079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059273701, states[0] = -94.414704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063492312, states[0] = -94.605355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068239542, states[0] = -94.288562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073278064, states[0] = -94.425600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077871884, states[0] = -94.565203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082589956, states[0] = -0.188879, states[40]= 0.001344
Saving checkpoint... 
Iteration: 1087078428, states[0] = 7.974434, states[40]= 0.000367
Saving checkpoint... 
Iteration: 1091527155, states[0] = 23.453405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096232742, states[0] = -94.253008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100986357, states[0] = -94.601773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105243758, states[0] = -94.304458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108584294, states[0] = 4.178788, states[40]= 0.000760
Saving checkpoint... 
Iteration: 1111972491, states[0] = -94.599354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116420846, states[0] = -94.587249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121114261, states[0] = -27.844798, states[40]= 0.002297
Saving checkpoint... 
Iteration: 1124173954, states[0] = -93.754644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128165096, states[0] = -93.002656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132570899, states[0] = 12.105469, states[40]= 0.000126
Saving checkpoint... 
Iteration: 1137082765, states[0] = 5.229561, states[40]= 0.000636
Saving checkpoint... 
Iteration: 1141504673, states[0] = 14.115227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146180447, states[0] = -93.851180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150835366, states[0] = -94.524723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155275812, states[0] = -94.412669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159805416, states[0] = -94.479262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164788342, states[0] = -94.443641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169598679, states[0] = -8.990579, states[40]= 0.001891
Saving checkpoint... 
Iteration: 1174245643, states[0] = -94.306818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178802814, states[0] = -94.472841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182756251, states[0] = -94.348007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186746580, states[0] = -94.309749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189571464, states[0] = 11.820863, states[40]= 0.000138
Saving checkpoint... 
Iteration: 1194579487, states[0] = 7.336615, states[40]= 0.000422
Saving checkpoint... 
Iteration: 1199163141, states[0] = -92.350549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1203332565, states[0] = -94.516955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206426579, states[0] = -94.581752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209432577, states[0] = -94.583314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212546027, states[0] = 21.416782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215467388, states[0] = -94.590162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218389694, states[0] = -94.565003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223098325, states[0] = -8.576327, states[40]= 0.001897
Saving checkpoint... 
Iteration: 1227682299, states[0] = -93.864775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231290790, states[0] = -94.443705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234025097, states[0] = 23.364687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236683382, states[0] = -93.875468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241135587, states[0] = -54.228434, states[40]= 0.000385
Saving checkpoint... 
Iteration: 1245601087, states[0] = -11.849881, states[40]= 0.001784
Saving checkpoint... 
Iteration: 1249755873, states[0] = -94.341037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254053893, states[0] = 19.218145, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1258491601, states[0] = -94.589301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262997154, states[0] = -94.589332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267579251, states[0] = 7.483934, states[40]= 0.000409
Saving checkpoint... 
Iteration: 1272392068, states[0] = -94.561875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277256101, states[0] = -94.339587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281869934, states[0] = -94.547003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285990461, states[0] = -94.586959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289720497, states[0] = -94.168119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293603852, states[0] = -15.231413, states[40]= 0.001629
Saving checkpoint... 
Iteration: 1297574064, states[0] = 10.461171, states[40]= 0.000201
Saving checkpoint... 
Iteration: 1301958492, states[0] = -94.581640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306310786, states[0] = -94.476613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311060954, states[0] = 16.647128, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1315870292, states[0] = -94.544477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319900137, states[0] = -94.562087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324138936, states[0] = -58.458375, states[40]= 0.000225
Saving checkpoint... 
Iteration: 1329155535, states[0] = -83.835672, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1332973701, states[0] = -94.581449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336695821, states[0] = -93.984000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340428214, states[0] = -94.571340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344480684, states[0] = -94.581319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348210252, states[0] = -94.095877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352100618, states[0] = -11.273403, states[40]= 0.001803
Saving checkpoint... 
Iteration: 1356118245, states[0] = -32.592728, states[40]= 0.002314
Saving checkpoint... 
Iteration: 1359365947, states[0] = -94.537637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363693692, states[0] = -93.963117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368616658, states[0] = -30.687329, states[40]= 0.002366
Saving checkpoint... 
Iteration: 1373411629, states[0] = -94.562774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378558944, states[0] = 17.438370, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1382735317, states[0] = -94.242042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387444773, states[0] = -94.571877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392103654, states[0] = -14.977778, states[40]= 0.001631
Saving checkpoint... 
Iteration: 1396385661, states[0] = -94.548110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400112058, states[0] = -25.190872, states[40]= 0.002065
Saving checkpoint... 
Iteration: 1403668464, states[0] = -93.480473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407364924, states[0] = -94.532864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410491302, states[0] = -94.576864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414703192, states[0] = -94.037796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418299178, states[0] = -94.446039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422219574, states[0] = -94.151370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425627988, states[0] = -44.582164, states[40]= 0.001089
Saving checkpoint... 
Iteration: 1430543965, states[0] = 21.877362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1434656640, states[0] = -85.689634, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1439835600, states[0] = -94.501256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443213853, states[0] = -94.112658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447760023, states[0] = -94.339429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450771903, states[0] = -94.377068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454913679, states[0] = -94.556873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458964274, states[0] = -94.569754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462634176, states[0] = -52.421741, states[40]= 0.000475
Saving checkpoint... 
Iteration: 1466794955, states[0] = -94.433351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470880677, states[0] = -94.538915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474859277, states[0] = -94.522622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478669243, states[0] = -93.534030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482653960, states[0] = -80.953663, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1487567994, states[0] = 13.542933, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1491406003, states[0] = -94.550725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495867387, states[0] = -94.527526, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.446002
 - CaMKt in component CaMK (millimolar): 0.028069
 - cass in component intracellular_ions (millimolar): 0.000108
 - nai in component intracellular_ions (millimolar): 7.899639
 - nass in component intracellular_ions (millimolar): 7.899815
 - ki in component intracellular_ions (millimolar): 143.054809
 - kss in component intracellular_ions (millimolar): 143.054770
 - cansr in component intracellular_ions (millimolar): 3.272334
 - cajsr in component intracellular_ions (millimolar): 3.251790
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.003789
 - hf in component INa (dimensionless): 0.871863
 - hs in component INa (dimensionless): 0.871861
 - j in component INa (dimensionless): 0.871838
 - hsp in component INa (dimensionless): 0.710687
 - jp in component INa (dimensionless): 0.871816
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.697584
 - hLp in component INaL (dimensionless): 0.438068
 - a in component Ito (dimensionless): 0.000643
 - iF in component Ito (dimensionless): 0.999859
 - iS in component Ito (dimensionless): 0.999859
 - ap in component Ito (dimensionless): 0.000328
 - iFp in component Ito (dimensionless): 0.999859
 - iSp in component Ito (dimensionless): 0.999859
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916795
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999865
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006777
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328439
 - xs1 in component IKs (dimensionless): 0.272233
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997454
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:23:12 (37977): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_1000-conf_306.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_1000-conf_306_0_r879855087_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_1000-conf_306_0_r879855087_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 102.809292
     * GNaL_b in INaL: 0.005835
     * Gto_b in Ito: 0.083854
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031862
     * GKs_b in IKs: 0.001920
     * GK1_b in IK1: 0.163070
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.211613
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033732
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1495867387
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.527526 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.446002
 - CaMKt in component CaMK (millimolar): 0.028069
 - cass in component intracellular_ions (millimolar): 0.000108
 - nai in component intracellular_ions (millimolar): 7.899639
 - nass in component intracellular_ions (millimolar): 7.899815
 - ki in component intracellular_ions (millimolar): 143.054809
 - kss in component intracellular_ions (millimolar): 143.054770
 - cansr in component intracellular_ions (millimolar): 3.272334
 - cajsr in component intracellular_ions (millimolar): 3.251790
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.003789
 - hf in component INa (dimensionless): 0.871863
 - hs in component INa (dimensionless): 0.871861
 - j in component INa (dimensionless): 0.871838
 - hsp in component INa (dimensionless): 0.710687
 - jp in component INa (dimensionless): 0.871816
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.697584
 - hLp in component INaL (dimensionless): 0.438068
 - a in component Ito (dimensionless): 0.000643
 - iF in component Ito (dimensionless): 0.999859
 - iS in component Ito (dimensionless): 0.999859
 - ap in component Ito (dimensionless): 0.000328
 - iFp in component Ito (dimensionless): 0.999859
 - iSp in component Ito (dimensionless): 0.999859
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916795
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999865
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006777
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328439
 - xs1 in component IKs (dimensionless): 0.272233
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997454
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:26:25 (39028): called boinc_finish(0)

</stderr_txt>
]]>


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