𝕏

Task 56197840

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-CLVPET_Block_Kr_15-conf_603_1
Workunit 26690464
Created 4 Jul 2024, 21:30:57 UTC
Sent 5 Jul 2024, 9:06:47 UTC
Report deadline 8 Jul 2024, 11:59:35 UTC
Received 6 Jul 2024, 8:07:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231343
Run time 57 min 25 sec
CPU time 46 min 56 sec
Validate state Valid
Credit 50.40
Device peak FLOPS 5.12 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.71 MB
Peak swap size 5.25 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-CLVPET_Block_Kr_15-conf_603.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-CLVPET_Block_Kr_15-conf_603_1_r222296561_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-CLVPET_Block_Kr_15-conf_603_1_r222296561_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.407153
     * GNaL_b in INaL: 0.005789
     * Gto_b in Ito: 0.083944
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.027073
     * GKs_b in IKs: 0.001939
     * GK1_b in IK1: 0.162811
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.223882
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032976
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7374317, states[0] = -94.921292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16636762, states[0] = -39.762318, states[40]= 0.000395
Saving checkpoint... 
Iteration: 26362312, states[0] = -94.831819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35953095, states[0] = -94.870541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45332731, states[0] = -94.786099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54946752, states[0] = -94.859747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64196472, states[0] = -94.303724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73668005, states[0] = -67.284234, states[40]= 0.000007
Saving checkpoint... 
Iteration: 83133558, states[0] = -34.803422, states[40]= 0.000852
Saving checkpoint... 
Iteration: 92726772, states[0] = -94.549377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102164246, states[0] = -62.906671, states[40]= 0.000014
Saving checkpoint... 
Iteration: 111586822, states[0] = 2.331585, states[40]= 0.004872
Saving checkpoint... 
Iteration: 121275191, states[0] = -94.683723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131129444, states[0] = -31.255068, states[40]= 0.001186
Saving checkpoint... 
Iteration: 141072030, states[0] = 9.891543, states[40]= 0.004529
Saving checkpoint... 
Iteration: 150320223, states[0] = -94.759198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160106914, states[0] = -12.275096, states[40]= 0.002253
Saving checkpoint... 
Iteration: 169517947, states[0] = 28.056458, states[40]= 0.004452
Saving checkpoint... 
Iteration: 179176061, states[0] = -77.649908, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188565236, states[0] = 12.865586, states[40]= 0.004095
Saving checkpoint... 
Iteration: 198178559, states[0] = -81.604466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 207819881, states[0] = -94.758142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216975890, states[0] = -94.860130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226368775, states[0] = -94.808459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236236447, states[0] = -94.579154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245735160, states[0] = -94.574915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255108240, states[0] = -13.408670, states[40]= 0.002051
Saving checkpoint... 
Iteration: 264504631, states[0] = 32.262165, states[40]= 0.286223
Saving checkpoint... 
Iteration: 273840110, states[0] = -94.781834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283452699, states[0] = -94.852862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290901008, states[0] = -94.829904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301647648, states[0] = -46.838465, states[40]= 0.000181
Saving checkpoint... 
Iteration: 311647578, states[0] = -46.774793, states[40]= 0.000183
Saving checkpoint... 
Iteration: 321884692, states[0] = -94.819669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331714991, states[0] = -94.501480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341767998, states[0] = -94.665741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351649342, states[0] = -48.383469, states[40]= 0.000144
Saving checkpoint... 
Iteration: 361755570, states[0] = -94.634826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369216185, states[0] = -94.506134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379040674, states[0] = 22.106310, states[40]= 0.002230
Saving checkpoint... 
Iteration: 388864767, states[0] = -94.804547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398710387, states[0] = -94.481321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408320733, states[0] = -94.758403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418088746, states[0] = 1.236952, states[40]= 0.004817
Saving checkpoint... 
Iteration: 427949750, states[0] = -94.851290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438290007, states[0] = -94.710688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448046649, states[0] = 20.012693, states[40]= 0.002640
Saving checkpoint... 
Iteration: 457760258, states[0] = -94.646578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467406148, states[0] = -94.832075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477670772, states[0] = -70.205291, states[40]= 0.000004
Saving checkpoint... 
Iteration: 488389434, states[0] = -94.822142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498377348, states[0] = -94.813861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508192372, states[0] = -93.896114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517830249, states[0] = -94.769815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527726214, states[0] = -94.543167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534369552, states[0] = -94.807840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544035910, states[0] = 23.697799, states[40]= 0.001957
Saving checkpoint... 
Iteration: 553662959, states[0] = -61.411881, states[40]= 0.000018
Saving checkpoint... 
Iteration: 563120603, states[0] = -23.943251, states[40]= 0.001530
Saving checkpoint... 
Iteration: 572558146, states[0] = 15.732185, states[40]= 0.003550
Saving checkpoint... 
Iteration: 579457646, states[0] = -94.853347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589208486, states[0] = -94.471164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599081695, states[0] = 5.186300, states[40]= 0.004889
Saving checkpoint... 
Iteration: 608951213, states[0] = -94.851103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618516436, states[0] = 28.196794, states[40]= 0.006561
Saving checkpoint... 
Iteration: 628023957, states[0] = 27.052696, states[40]= 0.001851
Saving checkpoint... 
Iteration: 637790596, states[0] = -94.710989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647571931, states[0] = 9.948626, states[40]= 0.004526
Saving checkpoint... 
Iteration: 657558184, states[0] = 15.717482, states[40]= 0.003553
Saving checkpoint... 
Iteration: 664301306, states[0] = -94.729182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674041240, states[0] = 21.912370, states[40]= 0.002266
Saving checkpoint... 
Iteration: 680629435, states[0] = -31.202911, states[40]= 0.001192
Saving checkpoint... 
Iteration: 690049619, states[0] = 18.940590, states[40]= 0.002865
Saving checkpoint... 
Iteration: 699636697, states[0] = -37.252526, states[40]= 0.000648
Saving checkpoint... 
Iteration: 709030577, states[0] = 25.345260, states[40]= 0.001734
Saving checkpoint... 
Iteration: 718674616, states[0] = -75.441855, states[40]= 0.000002
Saving checkpoint... 
Iteration: 728230108, states[0] = -94.556041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737735832, states[0] = -94.575176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744469276, states[0] = -94.856228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753943711, states[0] = -94.847879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763519548, states[0] = 27.858031, states[40]= 0.003155
Saving checkpoint... 
Iteration: 773157803, states[0] = -56.312208, states[40]= 0.000042
Saving checkpoint... 
Iteration: 782773255, states[0] = -94.675876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792424535, states[0] = -94.839906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802696779, states[0] = -94.288105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812623958, states[0] = -26.701832, states[40]= 0.001500
Saving checkpoint... 
Iteration: 823057243, states[0] = 16.082970, states[40]= 0.003477
Saving checkpoint... 
Iteration: 832955470, states[0] = -94.851672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842803175, states[0] = -94.731476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852656925, states[0] = -55.470258, states[40]= 0.000048
Saving checkpoint... 
Iteration: 862612515, states[0] = -17.117333, states[40]= 0.001604
Saving checkpoint... 
Iteration: 872287044, states[0] = -94.703531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878907678, states[0] = -94.831321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888233148, states[0] = -94.565735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897552752, states[0] = 17.786391, states[40]= 0.003114
Saving checkpoint... 
Iteration: 908409477, states[0] = -94.832157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918198459, states[0] = -94.349344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928122591, states[0] = -25.579103, states[40]= 0.001528
Saving checkpoint... 
Iteration: 938157269, states[0] = -55.798829, states[40]= 0.000046
Saving checkpoint... 
Iteration: 947967119, states[0] = -94.854830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958001735, states[0] = 46.640068, states[40]= 0.384124
Saving checkpoint... 
Iteration: 967895077, states[0] = -94.823821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977706074, states[0] = -94.455506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987744969, states[0] = -94.602637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998038859, states[0] = 22.723298, states[40]= 0.002119
Saving checkpoint... 
Iteration: 1008037860, states[0] = 23.057584, states[40]= 0.002062
Saving checkpoint... 
Iteration: 1017974125, states[0] = -94.856527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028051128, states[0] = 18.388097, states[40]= 0.002984
Saving checkpoint... 
Iteration: 1037771614, states[0] = -94.671269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047481578, states[0] = -94.858352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057446365, states[0] = -94.847686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067013382, states[0] = 28.314713, states[40]= 0.016241
Saving checkpoint... 
Iteration: 1076939288, states[0] = -94.844971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086796248, states[0] = -94.719181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096690465, states[0] = -93.502503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106319777, states[0] = -94.754464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116011452, states[0] = 28.307077, states[40]= 0.030196
Saving checkpoint... 
Iteration: 1125902867, states[0] = -94.827749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136367700, states[0] = -94.804065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146528905, states[0] = 25.819936, states[40]= 0.001697
Saving checkpoint... 
Iteration: 1156409856, states[0] = -94.831406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166204886, states[0] = -94.446283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176320190, states[0] = -94.754740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186050698, states[0] = 18.546421, states[40]= 0.002950
Saving checkpoint... 
Iteration: 1195823938, states[0] = -94.759497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205552433, states[0] = 17.905488, states[40]= 0.003088
Saving checkpoint... 
Iteration: 1215196381, states[0] = -94.267108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225152762, states[0] = -51.541967, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1234854074, states[0] = -94.791978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244997237, states[0] = -94.861204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254390576, states[0] = -94.819936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264193284, states[0] = -94.017178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274006031, states[0] = 29.830857, states[40]= 0.182171
Saving checkpoint... 
Iteration: 1283811756, states[0] = -94.742719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293651541, states[0] = -50.406348, states[40]= 0.000107
Saving checkpoint... 
Iteration: 1303685372, states[0] = -90.807478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313410757, states[0] = -94.831272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323075988, states[0] = 8.052856, states[40]= 0.004724
Saving checkpoint... 
Iteration: 1332802221, states[0] = -94.728077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342597046, states[0] = -4.262128, states[40]= 0.004049
Saving checkpoint... 
Iteration: 1352527739, states[0] = 26.135583, states[40]= 0.001688
Saving checkpoint... 
Iteration: 1362050542, states[0] = 18.603890, states[40]= 0.002938
Saving checkpoint... 
Iteration: 1371480397, states[0] = -94.856816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380926426, states[0] = -94.838495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390825648, states[0] = -94.760890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400810470, states[0] = -94.740406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410500887, states[0] = 45.809260, states[40]= 0.109672
Saving checkpoint... 
Iteration: 1419876601, states[0] = -94.809787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429532321, states[0] = 24.827642, states[40]= 0.001794
Saving checkpoint... 
Iteration: 1439457853, states[0] = -94.850124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449408775, states[0] = -94.829718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459090648, states[0] = 0.073442, states[40]= 0.004720
Saving checkpoint... 
Iteration: 1468752801, states[0] = -94.623091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478224506, states[0] = -94.533333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487970365, states[0] = -94.853694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497535530, states[0] = 23.821794, states[40]= 0.001938
Saving checkpoint... 
Iteration: 1507186692, states[0] = 19.749955, states[40]= 0.006005
Saving checkpoint... 
Iteration: 1516941923, states[0] = -94.616782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526552568, states[0] = -94.731310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536355889, states[0] = -11.111653, states[40]= 0.002543
Saving checkpoint... 
Iteration: 1545999252, states[0] = -94.745601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555586807, states[0] = -94.662689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565169451, states[0] = -53.307558, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1574967414, states[0] = -94.635201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584769407, states[0] = -94.257333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594482500, states[0] = -94.538349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604101311, states[0] = 1.249512, states[40]= 0.004532
Saving checkpoint... 
Iteration: 1613668898, states[0] = -94.521560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623538015, states[0] = -94.454906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633530523, states[0] = -94.447523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643144648, states[0] = -94.437951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652796886, states[0] = -94.201344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662482908, states[0] = -94.416766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672089429, states[0] = -94.416289, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.287964
 - CaMKt in component CaMK (millimolar): 0.001138
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.359994
 - nass in component intracellular_ions (millimolar): 6.360080
 - ki in component intracellular_ions (millimolar): 145.537342
 - kss in component intracellular_ions (millimolar): 145.537332
 - cansr in component intracellular_ions (millimolar): 1.567957
 - cajsr in component intracellular_ions (millimolar): 1.567980
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003850
 - hf in component INa (dimensionless): 0.868932
 - hs in component INa (dimensionless): 0.868933
 - j in component INa (dimensionless): 0.868934
 - hsp in component INa (dimensionless): 0.705334
 - jp in component INa (dimensionless): 0.868934
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.712685
 - hLp in component INaL (dimensionless): 0.520022
 - a in component Ito (dimensionless): 0.000650
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.997650
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.999214
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998765
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003009
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001908
 - xs1 in component IKs (dimensionless): 0.024278
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997494
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:06:32 (1252): called boinc_finish(0)

</stderr_txt>
]]>


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