𝕏

Task 56194392

Name HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_6000-conf_5_1
Workunit 26688742
Created 4 Jul 2024, 21:29:23 UTC
Sent 5 Jul 2024, 8:45:13 UTC
Report deadline 8 Jul 2024, 8:45:13 UTC
Received 5 Jul 2024, 17:26:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227546
Run time 1 hours 4 min 49 sec
CPU time 44 min 37 sec
Validate state Valid
Credit 46.77
Device peak FLOPS 4.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 8.41 MB
Peak swap size 32.99 GB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_6000-conf_5.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_6000-conf_5_1_r622092815_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_6000-conf_5_1_r622092815_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.776404
     * GNaL_b in INaL: 0.005766
     * Gto_b in Ito: 0.084905
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031825
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.163015
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.220658
     * GKb_b in IKb: 0.003809
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032133
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 21235235, states[0] = -93.795376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34349762, states[0] = -94.218731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50757536, states[0] = -94.186663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67832968, states[0] = -94.195000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84197472, states[0] = -93.281081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105150775, states[0] = -42.598472, states[40]= 0.000218
Saving checkpoint... 
Iteration: 119308186, states[0] = -94.197941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135382276, states[0] = -94.147816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152197170, states[0] = -94.201580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172464277, states[0] = -94.214296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194123358, states[0] = -94.203464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210192056, states[0] = -92.686036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225301144, states[0] = -94.003923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242742168, states[0] = -94.198488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262342136, states[0] = -94.217928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280180316, states[0] = -94.222923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294276996, states[0] = -93.925478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310448565, states[0] = -94.214783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330120087, states[0] = -10.427680, states[40]= 0.000277
Saving checkpoint... 
Iteration: 350342155, states[0] = -94.200696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370662624, states[0] = -94.209616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385370147, states[0] = -94.216273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401135828, states[0] = -94.202362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420570754, states[0] = -94.233577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440235579, states[0] = -94.200998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458542877, states[0] = -94.198243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472067825, states[0] = -94.225604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489173310, states[0] = -69.784833, states[40]= 0.000007
Saving checkpoint... 
Iteration: 505007936, states[0] = -94.227727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524793804, states[0] = -94.196144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542928290, states[0] = -94.195314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563159047, states[0] = -94.200824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582786438, states[0] = -94.235884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602113835, states[0] = -94.201020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620249865, states[0] = -94.199429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636481942, states[0] = -94.212540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653076608, states[0] = -94.201051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673468039, states[0] = -94.211453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690095949, states[0] = 7.305138, states[40]= 0.000059
Saving checkpoint... 
Iteration: 707236543, states[0] = -94.198871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722139895, states[0] = -94.199772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742182057, states[0] = -94.219270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761461693, states[0] = -94.196446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780955955, states[0] = -94.227685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802487472, states[0] = -94.209963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821413091, states[0] = -94.196362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841265215, states[0] = -94.215751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863785002, states[0] = -94.193503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882415131, states[0] = -94.175093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898948339, states[0] = -94.200752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919265044, states[0] = -94.215138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939519624, states[0] = -94.220961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960015795, states[0] = 23.401184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978114530, states[0] = -5.263583, states[40]= 0.000262
Saving checkpoint... 
Iteration: 992076324, states[0] = -94.198367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008527486, states[0] = -94.222117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027649605, states[0] = -94.204668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048263387, states[0] = -94.214169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064061454, states[0] = -94.197975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073774011, states[0] = -94.191898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086809052, states[0] = -94.231142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105517518, states[0] = -94.206860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121909795, states[0] = -94.190810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138144088, states[0] = -94.217478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150752164, states[0] = -94.201801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162957385, states[0] = -94.198536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183653158, states[0] = -94.203364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198593406, states[0] = -94.204455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216705384, states[0] = -94.202113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229683395, states[0] = -94.191194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242978023, states[0] = -94.223117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258582142, states[0] = -94.204218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277284687, states[0] = -94.193883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296969492, states[0] = -94.223042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316385804, states[0] = -94.192664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330775197, states[0] = -94.199978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346938202, states[0] = -94.188888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360392332, states[0] = -94.207951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376857997, states[0] = -94.189043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394409886, states[0] = -94.191843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412869744, states[0] = -94.188698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430737873, states[0] = -94.189271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447202919, states[0] = -94.212977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464956622, states[0] = -94.222246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478998883, states[0] = -94.187563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489559141, states[0] = -94.202881, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.063371
 - CaMKt in component CaMK (millimolar): 0.001368
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.060887
 - nass in component intracellular_ions (millimolar): 7.061022
 - ki in component intracellular_ions (millimolar): 144.653454
 - kss in component intracellular_ions (millimolar): 144.653442
 - cansr in component intracellular_ions (millimolar): 2.380368
 - cajsr in component intracellular_ions (millimolar): 2.380648
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003938
 - hf in component INa (dimensionless): 0.864672
 - hs in component INa (dimensionless): 0.864672
 - j in component INa (dimensionless): 0.864673
 - hsp in component INa (dimensionless): 0.697606
 - jp in component INa (dimensionless): 0.864674
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706502
 - hLp in component INaL (dimensionless): 0.512641
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999849
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999558
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005288
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000475
 - xs1 in component IKs (dimensionless): 0.014174
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997549
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:22:02 (74369): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_6000-conf_5.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_6000-conf_5_1_r622092815_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704232904935569_ORdGradInc_k_27-Drouin_EPI_6000-conf_5_1_r622092815_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.776404
     * GNaL_b in INaL: 0.005766
     * Gto_b in Ito: 0.084905
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031825
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.163015
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.220658
     * GKb_b in IKb: 0.003809
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032133
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1489559141
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.202881 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.063371
 - CaMKt in component CaMK (millimolar): 0.001368
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.060887
 - nass in component intracellular_ions (millimolar): 7.061022
 - ki in component intracellular_ions (millimolar): 144.653454
 - kss in component intracellular_ions (millimolar): 144.653442
 - cansr in component intracellular_ions (millimolar): 2.380368
 - cajsr in component intracellular_ions (millimolar): 2.380648
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003938
 - hf in component INa (dimensionless): 0.864672
 - hs in component INa (dimensionless): 0.864672
 - j in component INa (dimensionless): 0.864673
 - hsp in component INa (dimensionless): 0.697606
 - jp in component INa (dimensionless): 0.864674
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706502
 - hLp in component INaL (dimensionless): 0.512641
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999849
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999558
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005288
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000475
 - xs1 in component IKs (dimensionless): 0.014174
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997549
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:25:59 (90335): called boinc_finish(0)

</stderr_txt>
]]>