𝕏

Task 56190389

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_196_0
Workunit 26686743
Created 4 Jul 2024, 21:27:38 UTC
Sent 5 Jul 2024, 8:27:35 UTC
Report deadline 8 Jul 2024, 8:27:35 UTC
Received 5 Jul 2024, 13:18:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239744
Run time 1 hours 55 min 27 sec
CPU time 1 hours 55 min 11 sec
Validate state Valid
Credit 41.82
Device peak FLOPS 2.97 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 4.00 MB
Peak swap size 1.83 MB
Peak disk usage 0.12 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_196.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_196_0_r650439820_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_196_0_r650439820_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.039741
     * GNaL_b in INaL: 0.005840
     * Gto_b in Ito: 0.084621
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031788
     * GKs_b in IKs: 0.001936
     * GK1_b in IK1: 0.163730
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.164646
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033458
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13328245, states[0] = -84.988456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 26372737, states[0] = 18.429739, states[40]= 0.000018
Saving checkpoint... 
Iteration: 39479091, states[0] = -84.800181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 52709435, states[0] = 14.238391, states[40]= 0.000023
Saving checkpoint... 
Iteration: 65814931, states[0] = -84.906241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78981281, states[0] = -84.928317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 91830888, states[0] = 28.164353, states[40]= 0.222803
Saving checkpoint... 
Iteration: 104716092, states[0] = 4.938408, states[40]= 0.000125
Saving checkpoint... 
Iteration: 117558195, states[0] = -5.566038, states[40]= 0.000331
Saving checkpoint... 
Iteration: 130576802, states[0] = -33.636743, states[40]= 0.000273
Saving checkpoint... 
Iteration: 143696241, states[0] = 16.542467, states[40]= 0.000009
Saving checkpoint... 
Iteration: 157021695, states[0] = 20.518380, states[40]= 0.000006
Saving checkpoint... 
Iteration: 170194111, states[0] = 16.206469, states[40]= 0.000010
Saving checkpoint... 
Iteration: 182928355, states[0] = -65.570647, states[40]= 0.000017
Saving checkpoint... 
Iteration: 195764759, states[0] = -72.239638, states[40]= 0.000007
Saving checkpoint... 
Iteration: 208686083, states[0] = 18.804536, states[40]= 0.000005
Saving checkpoint... 
Iteration: 221767518, states[0] = -79.481087, states[40]= 0.000002
Saving checkpoint... 
Iteration: 234487667, states[0] = 29.131555, states[40]= 0.044517
Saving checkpoint... 
Iteration: 247495454, states[0] = 28.598431, states[40]= 0.001564
Saving checkpoint... 
Iteration: 260395516, states[0] = -31.488161, states[40]= 0.000281
Saving checkpoint... 
Iteration: 273619521, states[0] = -84.816697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 286398430, states[0] = -38.916412, states[40]= 0.000216
Saving checkpoint... 
Iteration: 299573515, states[0] = -51.787635, states[40]= 0.000076
Saving checkpoint... 
Iteration: 312564493, states[0] = -41.582355, states[40]= 0.000182
Saving checkpoint... 
Iteration: 325570734, states[0] = -51.555291, states[40]= 0.000079
Saving checkpoint... 
Iteration: 338865773, states[0] = -1.368030, states[40]= 0.000259
Saving checkpoint... 
Iteration: 352276586, states[0] = -84.784171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 365260496, states[0] = -83.781309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 377186500, states[0] = 6.823609, states[40]= 0.000087
Saving checkpoint... 
Iteration: 389969001, states[0] = 28.330331, states[40]= 0.141239
Saving checkpoint... 
Iteration: 403170566, states[0] = 16.362842, states[40]= 0.000009
Saving checkpoint... 
Iteration: 416696241, states[0] = -7.346423, states[40]= 0.000334
Saving checkpoint... 
Iteration: 429998858, states[0] = 17.846049, states[40]= 0.000006
Saving checkpoint... 
Iteration: 442931151, states[0] = -84.720193, states[40]= 0.000001
Saving checkpoint... 
Iteration: 456208112, states[0] = -29.891583, states[40]= 0.000284
Saving checkpoint... 
Iteration: 469533002, states[0] = -19.869929, states[40]= 0.000261
Saving checkpoint... 
Iteration: 482063130, states[0] = -62.627947, states[40]= 0.000024
Saving checkpoint... 
Iteration: 495095330, states[0] = -84.769913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 508174615, states[0] = 5.823859, states[40]= 0.000104
Saving checkpoint... 
Iteration: 521346996, states[0] = -0.785896, states[40]= 0.000245
Saving checkpoint... 
Iteration: 534268340, states[0] = -84.910004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 547583383, states[0] = -84.597115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 560623449, states[0] = 29.406619, states[40]= 0.023351
Saving checkpoint... 
Iteration: 573477410, states[0] = 22.022128, states[40]= 0.000010
Saving checkpoint... 
Iteration: 586797379, states[0] = 27.782031, states[40]= 0.000627
Saving checkpoint... 
Iteration: 599724984, states[0] = -73.128511, states[40]= 0.000006
Saving checkpoint... 
Iteration: 613291840, states[0] = 28.705256, states[40]= 0.001785
Saving checkpoint... 
Iteration: 627093124, states[0] = -84.913036, states[40]= 0.000001
Saving checkpoint... 
Iteration: 640484015, states[0] = 13.836444, states[40]= 0.000018
Saving checkpoint... 
Iteration: 653549158, states[0] = -67.332329, states[40]= 0.000014
Saving checkpoint... 
Iteration: 666872591, states[0] = -55.075869, states[40]= 0.000055
Saving checkpoint... 
Iteration: 679810733, states[0] = 15.619222, states[40]= 0.000011
Saving checkpoint... 
Iteration: 693509900, states[0] = -18.835095, states[40]= 0.000264
Saving checkpoint... 
Iteration: 706843027, states[0] = -20.466027, states[40]= 0.000260
Saving checkpoint... 
Iteration: 719702182, states[0] = -57.172855, states[40]= 0.000044
Saving checkpoint... 
Iteration: 732157845, states[0] = 0.676966, states[40]= 0.000212
Saving checkpoint... 
Iteration: 744853876, states[0] = -40.590496, states[40]= 0.000194
Saving checkpoint... 
Iteration: 757635346, states[0] = 16.224784, states[40]= 0.000010
Saving checkpoint... 
Iteration: 769234996, states[0] = -84.759814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 781720181, states[0] = -84.015169, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794840060, states[0] = -28.689464, states[40]= 0.000284
Saving checkpoint... 
Iteration: 808361743, states[0] = -59.607348, states[40]= 0.000034
Saving checkpoint... 
Iteration: 821528728, states[0] = -61.929914, states[40]= 0.000026
Saving checkpoint... 
Iteration: 834501507, states[0] = -26.947198, states[40]= 0.000279
Saving checkpoint... 
Iteration: 847674271, states[0] = -37.050247, states[40]= 0.000237
Saving checkpoint... 
Iteration: 860997261, states[0] = -24.708188, states[40]= 0.000270
Saving checkpoint... 
Iteration: 874258699, states[0] = 29.406435, states[40]= 0.023775
Saving checkpoint... 
Iteration: 887616490, states[0] = 19.832088, states[40]= 0.000005
Saving checkpoint... 
Iteration: 900703242, states[0] = -82.307306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 913996415, states[0] = -30.887054, states[40]= 0.000282
Saving checkpoint... 
Iteration: 927454754, states[0] = 14.222605, states[40]= 0.000017
Saving checkpoint... 
Iteration: 940607227, states[0] = 22.104576, states[40]= 0.000010
Saving checkpoint... 
Iteration: 953903754, states[0] = -84.999848, states[40]= 0.000001
Saving checkpoint... 
Iteration: 967086735, states[0] = 29.338650, states[40]= 0.005447
Saving checkpoint... 
Iteration: 980274735, states[0] = 19.332576, states[40]= 0.000005
Saving checkpoint... 
Iteration: 993795893, states[0] = 3.049671, states[40]= 0.000159
Saving checkpoint... 
Iteration: 1007035783, states[0] = -84.487782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1020426811, states[0] = 25.131155, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1033477374, states[0] = -20.938841, states[40]= 0.000260
Saving checkpoint... 
Iteration: 1046532312, states[0] = -84.510634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1060356350, states[0] = -83.352055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1073430260, states[0] = 20.411426, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1086379971, states[0] = -84.877768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1099150412, states[0] = -38.749095, states[40]= 0.000216
Saving checkpoint... 
Iteration: 1111698164, states[0] = -84.689740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124880101, states[0] = -84.921443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1137921466, states[0] = 21.753908, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1151112369, states[0] = 4.072931, states[40]= 0.000137
Saving checkpoint... 
Iteration: 1162955992, states[0] = -8.725343, states[40]= 0.000332
Saving checkpoint... 
Iteration: 1175419481, states[0] = 20.750508, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1188879377, states[0] = -84.976706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1202178365, states[0] = -84.019115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215210217, states[0] = -84.976705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228535891, states[0] = -84.909274, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1241447212, states[0] = -7.458553, states[40]= 0.000334
Saving checkpoint... 
Iteration: 1254422241, states[0] = 14.105803, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1267180645, states[0] = -84.633181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280261819, states[0] = 7.682515, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1293524292, states[0] = -84.845557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1306587195, states[0] = 11.681028, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1319296156, states[0] = -40.188764, states[40]= 0.000199
Saving checkpoint... 
Iteration: 1332124584, states[0] = -35.349402, states[40]= 0.000253
Saving checkpoint... 
Iteration: 1345319838, states[0] = -76.925373, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1358859197, states[0] = -84.933599, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1371892258, states[0] = 24.844558, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1383885426, states[0] = 27.382843, states[40]= 0.000422
Saving checkpoint... 
Iteration: 1395276997, states[0] = -24.434501, states[40]= 0.000269
Saving checkpoint... 
Iteration: 1406986312, states[0] = -82.448140, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1418430322, states[0] = -8.544154, states[40]= 0.000334
Saving checkpoint... 
Iteration: 1429934500, states[0] = -16.219051, states[40]= 0.000279
Saving checkpoint... 
Iteration: 1441128898, states[0] = -55.544474, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1454358428, states[0] = 30.273975, states[40]= 0.614945
Saving checkpoint... 
Iteration: 1468430062, states[0] = -15.354039, states[40]= 0.000287
Saving checkpoint... 
Iteration: 1481431194, states[0] = -18.907191, states[40]= 0.000263
Saving checkpoint... 
Iteration: 1494781121, states[0] = -43.490933, states[40]= 0.000158
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.850199
 - CaMKt in component CaMK (millimolar): 0.217195
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.289277
 - nass in component intracellular_ions (millimolar): 7.289630
 - ki in component intracellular_ions (millimolar): 143.828326
 - kss in component intracellular_ions (millimolar): 143.828291
 - cansr in component intracellular_ions (millimolar): 3.338658
 - cajsr in component intracellular_ions (millimolar): 1.927636
 - cai in component intracellular_ions (millimolar): 0.000162
 - m in component INa (dimensionless): 0.009954
 - hf in component INa (dimensionless): 0.584382
 - hs in component INa (dimensionless): 0.583331
 - j in component INa (dimensionless): 0.553638
 - hsp in component INa (dimensionless): 0.331809
 - jp in component INa (dimensionless): 0.511822
 - mL in component INaL (dimensionless): 0.000335
 - hL in component INaL (dimensionless): 0.182970
 - hLp in component INaL (dimensionless): 0.074625
 - a in component Ito (dimensionless): 0.001228
 - iF in component Ito (dimensionless): 0.999238
 - iS in component Ito (dimensionless): 0.131086
 - ap in component Ito (dimensionless): 0.000626
 - iFp in component Ito (dimensionless): 0.999238
 - iSp in component Ito (dimensionless): 0.146557
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.677314
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.928764
 - jca in component ICaL (dimensionless): 0.911294
 - ffp in component ICaL (dimensionless): 0.998922
 - fcafp in component ICaL (dimensionless): 0.999939
 - nca in component ICaL (dimensionless): 0.042079
 - xrf in component IKr (dimensionless): 0.101030
 - xrs in component IKr (dimensionless): 0.872749
 - xs1 in component IKs (dimensionless): 0.570727
 - xs2 in component IKs (dimensionless): 0.007218
 - xk1 in component IK1 (dimensionless): 0.996735
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
14:21:29 (4524): called boinc_finish(0)

</stderr_txt>
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