𝕏

Task 56189379

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_695_0
Workunit 26686238
Created 4 Jul 2024, 21:27:06 UTC
Sent 5 Jul 2024, 8:21:28 UTC
Report deadline 8 Jul 2024, 8:21:28 UTC
Received 6 Jul 2024, 1:16:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 221891
Run time 1 hours 59 min 46 sec
CPU time 1 hours 40 min
Validate state Valid
Credit 45.65
Device peak FLOPS 5.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.84 MB
Peak swap size 4.38 GB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_695.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_695_0_r22100609_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_695_0_r22100609_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.808648
     * GNaL_b in INaL: 0.005724
     * Gto_b in Ito: 0.084149
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031805
     * GKs_b in IKs: 0.001923
     * GK1_b in IK1: 0.164700
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.647082
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031808
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13892983, states[0] = -80.150122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 27050953, states[0] = 16.722938, states[40]= 0.000025
Saving checkpoint... 
Iteration: 41006255, states[0] = 29.772570, states[40]= 0.251743
Saving checkpoint... 
Iteration: 52898545, states[0] = -83.207841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64555139, states[0] = 14.050130, states[40]= 0.000025
Saving checkpoint... 
Iteration: 77842547, states[0] = -19.638995, states[40]= 0.000173
Saving checkpoint... 
Iteration: 90971541, states[0] = -84.770109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 104227643, states[0] = -84.801005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 117589882, states[0] = -16.537598, states[40]= 0.000181
Saving checkpoint... 
Iteration: 130862626, states[0] = -43.848934, states[40]= 0.000069
Saving checkpoint... 
Iteration: 143386745, states[0] = -74.557488, states[40]= 0.000001
Saving checkpoint... 
Iteration: 156563491, states[0] = 8.626185, states[40]= 0.000062
Saving checkpoint... 
Iteration: 169807506, states[0] = 12.467322, states[40]= 0.000032
Saving checkpoint... 
Iteration: 183438839, states[0] = -84.563922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 196571095, states[0] = 3.168348, states[40]= 0.000131
Saving checkpoint... 
Iteration: 209626597, states[0] = -60.734240, states[40]= 0.000010
Saving checkpoint... 
Iteration: 222847495, states[0] = -26.054273, states[40]= 0.000167
Saving checkpoint... 
Iteration: 235804524, states[0] = 14.276360, states[40]= 0.000022
Saving checkpoint... 
Iteration: 248898469, states[0] = -83.388216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261772659, states[0] = 29.978085, states[40]= 0.000686
Saving checkpoint... 
Iteration: 274325281, states[0] = -0.277894, states[40]= 0.000183
Saving checkpoint... 
Iteration: 287419133, states[0] = -84.377879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300227455, states[0] = -84.796969, states[40]= 0.000001
Saving checkpoint... 
Iteration: 313118846, states[0] = -51.214150, states[40]= 0.000032
Saving checkpoint... 
Iteration: 325874797, states[0] = -58.446950, states[40]= 0.000013
Saving checkpoint... 
Iteration: 338159382, states[0] = -84.234230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350761680, states[0] = 31.055885, states[40]= 0.036126
Saving checkpoint... 
Iteration: 363033989, states[0] = 25.317224, states[40]= 0.000013
Saving checkpoint... 
Iteration: 376322782, states[0] = 1.832078, states[40]= 0.000151
Saving checkpoint... 
Iteration: 390000344, states[0] = -41.872981, states[40]= 0.000014
Saving checkpoint... 
Iteration: 404004079, states[0] = 31.151883, states[40]= 0.549211
Saving checkpoint... 
Iteration: 417920354, states[0] = -84.386219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431986009, states[0] = -84.828892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 445951426, states[0] = -84.646765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 460032768, states[0] = 25.893760, states[40]= 0.000020
Saving checkpoint... 
Iteration: 474088051, states[0] = -14.288205, states[40]= 0.000194
Saving checkpoint... 
Iteration: 488119411, states[0] = -51.875658, states[40]= 0.000029
Saving checkpoint... 
Iteration: 502204106, states[0] = -84.662293, states[40]= 0.000001
Saving checkpoint... 
Iteration: 516100510, states[0] = -29.664881, states[40]= 0.000165
Saving checkpoint... 
Iteration: 529985437, states[0] = -84.823016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 543865354, states[0] = -47.076955, states[40]= 0.000050
Saving checkpoint... 
Iteration: 556278714, states[0] = 27.704999, states[40]= 0.000080
Saving checkpoint... 
Iteration: 568728809, states[0] = -84.793318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 580357628, states[0] = -38.052472, states[40]= 0.000112
Saving checkpoint... 
Iteration: 592047855, states[0] = 18.127396, states[40]= 0.000009
Saving checkpoint... 
Iteration: 604719086, states[0] = -84.745169, states[40]= 0.000001
Saving checkpoint... 
Iteration: 616553573, states[0] = 14.847348, states[40]= 0.000020
Saving checkpoint... 
Iteration: 628571053, states[0] = 3.209056, states[40]= 0.000131
Saving checkpoint... 
Iteration: 642286773, states[0] = 23.968377, states[40]= 0.000006
Saving checkpoint... 
Iteration: 655332972, states[0] = -8.067163, states[40]= 0.000234
Saving checkpoint... 
Iteration: 666132882, states[0] = -69.178720, states[40]= 0.000003
Saving checkpoint... 
Iteration: 676685348, states[0] = -84.517308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 686618745, states[0] = -51.070033, states[40]= 0.000032
Saving checkpoint... 
Iteration: 697749743, states[0] = -84.869376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 708515425, states[0] = 31.377367, states[40]= 0.009273
Saving checkpoint... 
Iteration: 721014738, states[0] = 31.385331, states[40]= 0.011894
Saving checkpoint... 
Iteration: 734954054, states[0] = -84.653410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 748986513, states[0] = -84.819394, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763072238, states[0] = 2.280247, states[40]= 0.000145
Saving checkpoint... 
Iteration: 776698706, states[0] = -84.616026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 787888259, states[0] = -76.477170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 800773078, states[0] = 29.851235, states[40]= 0.000590
Saving checkpoint... 
Iteration: 813385845, states[0] = -73.308025, states[40]= 0.000002
Saving checkpoint... 
Iteration: 825930157, states[0] = -84.466555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837987903, states[0] = -84.821666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 850571575, states[0] = 2.807497, states[40]= 0.000137
Saving checkpoint... 
Iteration: 863251659, states[0] = 36.695686, states[40]= 1.128127
Saving checkpoint... 
Iteration: 875852203, states[0] = -31.659862, states[40]= 0.000157
Saving checkpoint... 
Iteration: 887712851, states[0] = -84.701045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 900321016, states[0] = 3.244388, states[40]= 0.000130
Saving checkpoint... 
Iteration: 913058671, states[0] = 11.751213, states[40]= 0.000036
Saving checkpoint... 
Iteration: 925843249, states[0] = -20.810714, states[40]= 0.000163
Saving checkpoint... 
Iteration: 938525418, states[0] = 29.031495, states[40]= 0.000256
Saving checkpoint... 
Iteration: 951197043, states[0] = -84.597876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962905705, states[0] = -84.098104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975287342, states[0] = 23.690308, states[40]= 0.000006
Saving checkpoint... 
Iteration: 987759050, states[0] = 30.319622, states[40]= 0.093784
Saving checkpoint... 
Iteration: 1000301482, states[0] = 16.075685, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1012226363, states[0] = -84.765995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024524280, states[0] = 29.446513, states[40]= 0.000384
Saving checkpoint... 
Iteration: 1036902160, states[0] = -83.874327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047240089, states[0] = -84.822503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1059872722, states[0] = -55.827748, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1072318547, states[0] = 5.104958, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1084058194, states[0] = 12.052097, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1096083600, states[0] = -8.781801, states[40]= 0.000232
Saving checkpoint... 
Iteration: 1108507826, states[0] = 29.918237, states[40]= 0.145832
Saving checkpoint... 
Iteration: 1120842685, states[0] = -20.097484, states[40]= 0.000164
Saving checkpoint... 
Iteration: 1133245025, states[0] = -84.837476, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1145985222, states[0] = -84.799743, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159067808, states[0] = 5.643552, states[40]= 0.000096
Saving checkpoint... 
Iteration: 1172395181, states[0] = -82.278003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185695585, states[0] = -84.578719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1198864454, states[0] = -45.982827, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1212316465, states[0] = 6.600500, states[40]= 0.000084
Saving checkpoint... 
Iteration: 1225745735, states[0] = -84.836618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1239218533, states[0] = -84.719115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1252571206, states[0] = 3.105727, states[40]= 0.000132
Saving checkpoint... 
Iteration: 1266105249, states[0] = -35.231202, states[40]= 0.000134
Saving checkpoint... 
Iteration: 1279626417, states[0] = -60.420026, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1293172309, states[0] = -84.373946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306613944, states[0] = -45.379757, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1320082763, states[0] = -7.796547, states[40]= 0.000234
Saving checkpoint... 
Iteration: 1333586884, states[0] = -12.777922, states[40]= 0.000206
Saving checkpoint... 
Iteration: 1347140125, states[0] = -78.539542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360609777, states[0] = -40.516057, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1374123808, states[0] = -57.138055, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1387336358, states[0] = -12.119079, states[40]= 0.000211
Saving checkpoint... 
Iteration: 1400607864, states[0] = -38.283423, states[40]= 0.000110
Saving checkpoint... 
Iteration: 1413968663, states[0] = -84.713407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1426477377, states[0] = -84.755578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1438947389, states[0] = -84.582374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1451364971, states[0] = -46.573295, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1464051222, states[0] = 16.232992, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1476475110, states[0] = -84.743186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1488806179, states[0] = 13.298853, states[40]= 0.000027
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.716907
 - CaMKt in component CaMK (millimolar): 0.082414
 - cass in component intracellular_ions (millimolar): 0.000121
 - nai in component intracellular_ions (millimolar): 6.987949
 - nass in component intracellular_ions (millimolar): 6.988152
 - ki in component intracellular_ions (millimolar): 144.488982
 - kss in component intracellular_ions (millimolar): 144.488951
 - cansr in component intracellular_ions (millimolar): 2.470113
 - cajsr in component intracellular_ions (millimolar): 1.899978
 - cai in component intracellular_ions (millimolar): 0.000119
 - m in component INa (dimensionless): 0.010088
 - hf in component INa (dimensionless): 0.579062
 - hs in component INa (dimensionless): 0.578707
 - j in component INa (dimensionless): 0.576462
 - hsp in component INa (dimensionless): 0.330787
 - jp in component INa (dimensionless): 0.572641
 - mL in component INaL (dimensionless): 0.000343
 - hL in component INaL (dimensionless): 0.293348
 - hLp in component INaL (dimensionless): 0.122840
 - a in component Ito (dimensionless): 0.001239
 - iF in component Ito (dimensionless): 0.999223
 - iS in component Ito (dimensionless): 0.253218
 - ap in component Ito (dimensionless): 0.000631
 - iFp in component Ito (dimensionless): 0.999223
 - iSp in component Ito (dimensionless): 0.280138
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.781099
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.981503
 - jca in component ICaL (dimensionless): 0.986190
 - ffp in component ICaL (dimensionless): 0.999999
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.010603
 - xrf in component IKr (dimensionless): 0.007027
 - xrs in component IKr (dimensionless): 0.771897
 - xs1 in component IKs (dimensionless): 0.464650
 - xs2 in component IKs (dimensionless): 0.000352
 - xk1 in component IK1 (dimensionless): 0.996751
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
18:55:08 (35372): called boinc_finish(0)

</stderr_txt>
]]>


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