𝕏

Task 56186677

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_3000-conf_593_1
Workunit 26684887
Created 4 Jul 2024, 21:25:53 UTC
Sent 5 Jul 2024, 8:02:22 UTC
Report deadline 8 Jul 2024, 8:02:22 UTC
Received 5 Jul 2024, 10:38:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241714
Run time 1 hours 15 min 56 sec
CPU time 1 hours 15 min 50 sec
Validate state Valid
Credit 43.31
Device peak FLOPS 4.33 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.30 MB
Peak swap size 1.34 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_3000-conf_593.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_3000-conf_593_1_r1310535926_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_3000-conf_593_1_r1310535926_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.937924
     * GNaL_b in INaL: 0.005839
     * Gto_b in Ito: 0.084148
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031888
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.162871
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.214578
     * GKb_b in IKb: 0.003808
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032191
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11671142, states[0] = -94.110675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23347525, states[0] = -94.053856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34948173, states[0] = -93.968749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46448396, states[0] = -93.999615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57996369, states[0] = -94.014291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69637106, states[0] = -94.016155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81287617, states[0] = -93.681112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92875142, states[0] = -93.997808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104296393, states[0] = -94.020003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115907486, states[0] = -93.920878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127666961, states[0] = -46.933148, states[40]= 0.000345
Saving checkpoint... 
Iteration: 139253196, states[0] = -94.002209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150789508, states[0] = -94.020061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162314518, states[0] = -93.762096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173930171, states[0] = -93.995858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185709882, states[0] = -94.003813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197374481, states[0] = -94.017762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208941691, states[0] = -93.951023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220393807, states[0] = -93.996924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232032471, states[0] = -94.011214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243659034, states[0] = -94.017288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255176217, states[0] = -54.484837, states[40]= 0.000113
Saving checkpoint... 
Iteration: 266747276, states[0] = -94.002090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278345675, states[0] = -94.018431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290393818, states[0] = -94.016788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302081663, states[0] = -94.007841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314024698, states[0] = -93.993426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325833068, states[0] = -93.806020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337785367, states[0] = -93.672479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349788927, states[0] = -93.684762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361756338, states[0] = -93.555188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373610079, states[0] = -2.295346, states[40]= 0.003570
Saving checkpoint... 
Iteration: 385513565, states[0] = 31.398322, states[40]= 0.017155
Saving checkpoint... 
Iteration: 397434405, states[0] = -93.995027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409453550, states[0] = -93.994380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421757267, states[0] = -93.559203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433838405, states[0] = -93.816977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445731791, states[0] = -93.423570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457514705, states[0] = 31.533383, states[40]= 0.011558
Saving checkpoint... 
Iteration: 469460938, states[0] = -93.993955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481469931, states[0] = -93.993637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493472794, states[0] = -93.993510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505463936, states[0] = -93.993746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517470548, states[0] = -93.993502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529296064, states[0] = -93.999394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541137711, states[0] = -94.005672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553171624, states[0] = -94.004213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565108599, states[0] = -94.006838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576914755, states[0] = -94.015078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589221878, states[0] = -94.002056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601491003, states[0] = -93.992607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613734870, states[0] = -93.445536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625992004, states[0] = -93.979547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637972431, states[0] = -93.969580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649863736, states[0] = -93.862399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661778559, states[0] = -93.646632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673686139, states[0] = -62.812442, states[40]= 0.000029
Saving checkpoint... 
Iteration: 685679389, states[0] = -57.089550, states[40]= 0.000075
Saving checkpoint... 
Iteration: 697721742, states[0] = -93.191471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709777595, states[0] = -93.642833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721653735, states[0] = -36.430641, states[40]= 0.001257
Saving checkpoint... 
Iteration: 733693206, states[0] = -69.509701, states[40]= 0.000010
Saving checkpoint... 
Iteration: 745609282, states[0] = -1.771700, states[40]= 0.003594
Saving checkpoint... 
Iteration: 757599777, states[0] = 3.776668, states[40]= 0.003315
Saving checkpoint... 
Iteration: 769882592, states[0] = -93.889536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782155567, states[0] = -94.015324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794324098, states[0] = -94.017362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806511140, states[0] = -94.010309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818732830, states[0] = -94.000886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830839072, states[0] = -93.996863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842667799, states[0] = -94.003443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854583468, states[0] = -94.006997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866552661, states[0] = -94.008302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878583486, states[0] = -94.006919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890632590, states[0] = -94.004769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902579411, states[0] = -94.007019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914537611, states[0] = -94.008807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926459377, states[0] = -94.012146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938307261, states[0] = -94.017277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950197804, states[0] = -94.016966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962447355, states[0] = -94.012532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974469165, states[0] = -94.011579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986309189, states[0] = -94.017084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998337454, states[0] = -94.016360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010309877, states[0] = -94.016993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022254298, states[0] = -94.017592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034286761, states[0] = -94.017316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046353547, states[0] = -94.015736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058385935, states[0] = -94.014615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070184646, states[0] = -94.016073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082050625, states[0] = -93.998570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093962022, states[0] = -93.962018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106039179, states[0] = -93.995382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118038183, states[0] = -93.995055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129925325, states[0] = -93.934797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142013454, states[0] = -93.986803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154043543, states[0] = -93.996458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166122046, states[0] = -94.011007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178251547, states[0] = -94.017092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190252096, states[0] = -94.017054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202402215, states[0] = -94.013555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214561204, states[0] = -94.006813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226878476, states[0] = -93.994219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239179457, states[0] = -57.142407, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1251297740, states[0] = -93.710517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263385962, states[0] = -93.892347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275407173, states[0] = -93.916931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287511378, states[0] = -93.985554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299814414, states[0] = -94.015968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312088940, states[0] = -94.005293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324295706, states[0] = -93.996857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336354960, states[0] = -93.994681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348233782, states[0] = -93.999150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360738521, states[0] = -93.464650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373123566, states[0] = -94.010516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385566039, states[0] = -94.006054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397896113, states[0] = -93.993074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410198397, states[0] = -75.375535, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1422555190, states[0] = -93.998620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434605652, states[0] = -94.008072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446856350, states[0] = -94.014366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459150950, states[0] = -94.002170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471744803, states[0] = -93.496805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484182294, states[0] = -94.014642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496596190, states[0] = -94.004387, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.865411
 - CaMKt in component CaMK (millimolar): 0.003122
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.774824
 - nass in component intracellular_ions (millimolar): 6.774946
 - ki in component intracellular_ions (millimolar): 145.077033
 - kss in component intracellular_ions (millimolar): 145.077022
 - cansr in component intracellular_ions (millimolar): 1.836492
 - cajsr in component intracellular_ions (millimolar): 1.836314
 - cai in component intracellular_ions (millimolar): 0.000103
 - m in component INa (dimensionless): 0.004018
 - hf in component INa (dimensionless): 0.860821
 - hs in component INa (dimensionless): 0.860822
 - j in component INa (dimensionless): 0.860830
 - hsp in component INa (dimensionless): 0.690707
 - jp in component INa (dimensionless): 0.860834
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.701069
 - hLp in component INaL (dimensionless): 0.502786
 - a in component Ito (dimensionless): 0.000669
 - iF in component Ito (dimensionless): 0.999844
 - iS in component Ito (dimensionless): 0.968763
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999844
 - iSp in component Ito (dimensionless): 0.984162
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990164
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005033
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.030110
 - xs1 in component IKs (dimensionless): 0.072590
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997596
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:08:57 (1652): called boinc_finish(0)

</stderr_txt>
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