𝕏

Task 56180860

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_387_1
Workunit 26681986
Created 4 Jul 2024, 21:23:15 UTC
Sent 5 Jul 2024, 7:28:24 UTC
Report deadline 8 Jul 2024, 7:28:24 UTC
Received 5 Jul 2024, 23:15:24 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 221891
Run time 1 hours 53 min 6 sec
CPU time 1 hours 36 min 26 sec
Validate state Valid
Credit 43.23
Device peak FLOPS 5.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.84 MB
Peak swap size 4.26 GB
Peak disk usage 0.15 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_387.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_387_1_r716170261_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_387_1_r716170261_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.129406
     * GNaL_b in INaL: 0.005881
     * Gto_b in Ito: 0.084472
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031920
     * GKs_b in IKs: 0.001934
     * GK1_b in IK1: 0.164243
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.493327
     * GKb_b in IKb: 0.003808
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033413
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 7500.000000
     * CL_0 in membrane: 400.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499800000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8669408, states[0] = 1.719670, states[40]= 0.002978
Saving checkpoint... 
Iteration: 16835146, states[0] = 23.732756, states[40]= 0.000022
Saving checkpoint... 
Iteration: 25209839, states[0] = 30.222979, states[40]= 0.068730
Saving checkpoint... 
Iteration: 34892697, states[0] = -26.904636, states[40]= 0.000279


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_387.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_387_1_r716170261_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_387_1_r716170261_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.129406
     * GNaL_b in INaL: 0.005881
     * Gto_b in Ito: 0.084472
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031920
     * GKs_b in IKs: 0.001934
     * GK1_b in IK1: 0.164243
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.493327
     * GKb_b in IKb: 0.003808
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033413
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 7500.000000
     * CL_0 in membrane: 400.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499800000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 34892697
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -26.904636 (After loading)
 - states[40]: 0.000279 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 48421413, states[0] = 29.723010, states[40]= 0.001045
Saving checkpoint... 
Iteration: 62016325, states[0] = 30.671160, states[40]= 0.006607
Saving checkpoint... 
Iteration: 74891722, states[0] = -27.307772, states[40]= 0.000208
Saving checkpoint... 
Iteration: 86934952, states[0] = -82.193284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 99509929, states[0] = -50.645007, states[40]= 0.000052
Saving checkpoint... 
Iteration: 112813588, states[0] = 30.588194, states[40]= 0.018064
Saving checkpoint... 
Iteration: 126141479, states[0] = -84.082642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139498535, states[0] = -36.544279, states[40]= 0.000158
Saving checkpoint... 
Iteration: 152280709, states[0] = -13.012744, states[40]= 0.000215
Saving checkpoint... 
Iteration: 165516268, states[0] = -59.095656, states[40]= 0.000020
Saving checkpoint... 
Iteration: 178823034, states[0] = 28.967911, states[40]= 0.000572
Saving checkpoint... 
Iteration: 191986165, states[0] = -84.907705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 205629533, states[0] = 26.265382, states[40]= 0.000056
Saving checkpoint... 
Iteration: 218735820, states[0] = -82.778784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 231887569, states[0] = -22.390795, states[40]= 0.000180
Saving checkpoint... 
Iteration: 245192200, states[0] = -84.948577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 258291083, states[0] = -27.036761, states[40]= 0.000191
Saving checkpoint... 
Iteration: 271496332, states[0] = -33.801498, states[40]= 0.000177
Saving checkpoint... 
Iteration: 284805871, states[0] = 29.012225, states[40]= 0.308189
Saving checkpoint... 
Iteration: 298078591, states[0] = -10.183109, states[40]= 0.000230
Saving checkpoint... 
Iteration: 311818031, states[0] = 30.319695, states[40]= 0.003518
Saving checkpoint... 
Iteration: 325271655, states[0] = -1.930950, states[40]= 0.000193
Saving checkpoint... 
Iteration: 338525610, states[0] = -72.450893, states[40]= 0.000004
Saving checkpoint... 
Iteration: 351816475, states[0] = 30.533293, states[40]= 0.006224
Saving checkpoint... 
Iteration: 365252135, states[0] = 13.535953, states[40]= 0.000017
Saving checkpoint... 
Iteration: 378437724, states[0] = 22.098692, states[40]= 0.000004
Saving checkpoint... 
Iteration: 391714066, states[0] = -56.193392, states[40]= 0.000028
Saving checkpoint... 
Iteration: 404972234, states[0] = -84.779000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 417867716, states[0] = 1.865060, states[40]= 0.000136
Saving checkpoint... 
Iteration: 431051712, states[0] = 13.811690, states[40]= 0.000016
Saving checkpoint... 
Iteration: 443345870, states[0] = -84.375276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457216666, states[0] = 30.515534, states[40]= 0.005802
Saving checkpoint... 
Iteration: 470576044, states[0] = -84.810588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 483614239, states[0] = 30.610259, states[40]= 0.014189
Saving checkpoint... 
Iteration: 496965861, states[0] = -84.710676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 510882427, states[0] = -15.376656, states[40]= 0.000198
Saving checkpoint... 
Iteration: 524221846, states[0] = 29.368119, states[40]= 0.000878
Saving checkpoint... 
Iteration: 537740361, states[0] = -83.927535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550849360, states[0] = 15.311063, states[40]= 0.000011
Saving checkpoint... 
Iteration: 563095397, states[0] = -32.589106, states[40]= 0.000183
Saving checkpoint... 
Iteration: 575629753, states[0] = 26.168612, states[40]= 0.000052
Saving checkpoint... 
Iteration: 588145554, states[0] = -84.353567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600648521, states[0] = 15.834875, states[40]= 0.000010
Saving checkpoint... 
Iteration: 613305680, states[0] = -45.525650, states[40]= 0.000082
Saving checkpoint... 
Iteration: 626108989, states[0] = -49.680515, states[40]= 0.000055
Saving checkpoint... 
Iteration: 638337000, states[0] = -83.176562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651660141, states[0] = 8.005334, states[40]= 0.000055
Saving checkpoint... 
Iteration: 663995172, states[0] = -84.947046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 677213825, states[0] = 30.593515, states[40]= 0.016533
Saving checkpoint... 
Iteration: 690774102, states[0] = -84.781672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 705164870, states[0] = -84.689364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 719676306, states[0] = -7.217210, states[40]= 0.000234
Saving checkpoint... 
Iteration: 734291208, states[0] = -27.167736, states[40]= 0.000191
Saving checkpoint... 
Iteration: 748888587, states[0] = -23.714693, states[40]= 0.000182
Saving checkpoint... 
Iteration: 763284269, states[0] = -17.886753, states[40]= 0.000185
Saving checkpoint... 
Iteration: 777850284, states[0] = 14.733804, states[40]= 0.000013
Saving checkpoint... 
Iteration: 792398755, states[0] = -84.963167, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806677705, states[0] = -8.990453, states[40]= 0.000234
Saving checkpoint... 
Iteration: 820720341, states[0] = -64.667663, states[40]= 0.000010
Saving checkpoint... 
Iteration: 834575172, states[0] = -84.784007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 848624879, states[0] = 28.293179, states[40]= 0.000294
Saving checkpoint... 
Iteration: 863776926, states[0] = -84.798131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 878992102, states[0] = -84.915523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 894225434, states[0] = 28.073301, states[40]= 0.000241
Saving checkpoint... 
Iteration: 909541938, states[0] = -84.091529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924881590, states[0] = -14.199694, states[40]= 0.000205
Saving checkpoint... 
Iteration: 940413904, states[0] = 30.602159, states[40]= 0.016051
Saving checkpoint... 
Iteration: 955871103, states[0] = -1.337488, states[40]= 0.000185
Saving checkpoint... 
Iteration: 971389512, states[0] = -84.892640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 986872000, states[0] = -2.261437, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1002470350, states[0] = -0.583881, states[40]= 0.000174
Saving checkpoint... 
Iteration: 1017950886, states[0] = -84.485516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033563791, states[0] = -84.660645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1048976589, states[0] = -84.785621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1064415634, states[0] = 30.607468, states[40]= 0.008473
Saving checkpoint... 
Iteration: 1079779037, states[0] = -84.805250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1095234466, states[0] = 23.842632, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1110698672, states[0] = -36.705530, states[40]= 0.000155
Saving checkpoint... 
Iteration: 1126053463, states[0] = 12.682454, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1141552536, states[0] = -84.509010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156906140, states[0] = -46.058802, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1172276434, states[0] = -7.350728, states[40]= 0.000234
Saving checkpoint... 
Iteration: 1187835250, states[0] = 23.435936, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1203371570, states[0] = -84.731446, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1218841681, states[0] = 19.912933, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1234292964, states[0] = -29.414795, states[40]= 0.000192
Saving checkpoint... 
Iteration: 1249720215, states[0] = -64.435694, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1265328287, states[0] = -76.070259, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1280469497, states[0] = 0.252714, states[40]= 0.000161
Saving checkpoint... 
Iteration: 1295243666, states[0] = 18.769161, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1307959476, states[0] = -84.596905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321892529, states[0] = -28.845465, states[40]= 0.000192
Saving checkpoint... 
Iteration: 1334852321, states[0] = 13.437280, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1345589798, states[0] = -84.875518, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358843803, states[0] = 18.690454, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1372111370, states[0] = -52.632535, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1385472311, states[0] = -2.571831, states[40]= 0.000201
Saving checkpoint... 
Iteration: 1398660143, states[0] = 8.024253, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1412003490, states[0] = 31.917348, states[40]= 0.709111
Saving checkpoint... 
Iteration: 1424644821, states[0] = 18.092956, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1437688056, states[0] = -22.960005, states[40]= 0.000180
Saving checkpoint... 
Iteration: 1451113124, states[0] = -54.872036, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1464325940, states[0] = -72.759319, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1478034612, states[0] = 23.774718, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1490738756, states[0] = -83.574405, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.810338
 - CaMKt in component CaMK (millimolar): 0.148131
 - cass in component intracellular_ions (millimolar): 0.000143
 - nai in component intracellular_ions (millimolar): 7.148934
 - nass in component intracellular_ions (millimolar): 7.149201
 - ki in component intracellular_ions (millimolar): 144.125083
 - kss in component intracellular_ions (millimolar): 144.125049
 - cansr in component intracellular_ions (millimolar): 2.936989
 - cajsr in component intracellular_ions (millimolar): 1.951376
 - cai in component intracellular_ions (millimolar): 0.000137
 - m in component INa (dimensionless): 0.009994
 - hf in component INa (dimensionless): 0.582796
 - hs in component INa (dimensionless): 0.582143
 - j in component INa (dimensionless): 0.574432
 - hsp in component INa (dimensionless): 0.333201
 - jp in component INa (dimensionless): 0.557724
 - mL in component INaL (dimensionless): 0.000337
 - hL in component INaL (dimensionless): 0.237343
 - hLp in component INaL (dimensionless): 0.097673
 - a in component Ito (dimensionless): 0.001231
 - iF in component Ito (dimensionless): 0.999234
 - iS in component Ito (dimensionless): 0.180748
 - ap in component Ito (dimensionless): 0.000627
 - iFp in component Ito (dimensionless): 0.999235
 - iSp in component Ito (dimensionless): 0.201382
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.725760
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.957598
 - jca in component ICaL (dimensionless): 0.956952
 - ffp in component ICaL (dimensionless): 0.999938
 - fcafp in component ICaL (dimensionless): 0.999997
 - nca in component ICaL (dimensionless): 0.020345
 - xrf in component IKr (dimensionless): 0.035914
 - xrs in component IKr (dimensionless): 0.832809
 - xs1 in component IKs (dimensionless): 0.524534
 - xs2 in component IKs (dimensionless): 0.001485
 - xk1 in component IK1 (dimensionless): 0.996733
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
17:12:04 (1970): called boinc_finish(0)

</stderr_txt>
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