𝕏

Task 56180796

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_2000-conf_187_1
Workunit 26681954
Created 4 Jul 2024, 21:23:10 UTC
Sent 5 Jul 2024, 7:27:12 UTC
Report deadline 8 Jul 2024, 7:27:12 UTC
Received 5 Jul 2024, 23:15:24 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 221891
Run time 1 hours 53 min 18 sec
CPU time 1 hours 36 min 2 sec
Validate state Valid
Credit 43.83
Device peak FLOPS 5.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.07 MB
Peak swap size 4.37 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_2000-conf_187.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_2000-conf_187_1_r115501501_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_2000-conf_187_1_r115501501_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.233292
     * GNaL_b in INaL: 0.005910
     * Gto_b in Ito: 0.083842
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031846
     * GKs_b in IKs: 0.001920
     * GK1_b in IK1: 0.163341
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.581480
     * GKb_b in IKb: 0.003803
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033074
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10466541, states[0] = -84.323767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 20837086, states[0] = -84.281425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 29879659, states[0] = -84.241418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 38524522, states[0] = -84.195904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 46413817, states[0] = -84.112773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 54701170, states[0] = -84.196165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66001892, states[0] = 35.521329, states[40]= 0.879837


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_2000-conf_187.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_2000-conf_187_1_r115501501_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_2000-conf_187_1_r115501501_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.233292
     * GNaL_b in INaL: 0.005910
     * Gto_b in Ito: 0.083842
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031846
     * GKs_b in IKs: 0.001920
     * GK1_b in IK1: 0.163341
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.581480
     * GKb_b in IKb: 0.003803
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033074
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 66001892
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 35.521329 (After loading)
 - states[40]: 0.879837 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 79464116, states[0] = -84.120960, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93146486, states[0] = -40.538378, states[40]= 0.000173
Saving checkpoint... 
Iteration: 105981351, states[0] = -84.155470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 118101250, states[0] = -1.062396, states[40]= 0.000809
Saving checkpoint... 
Iteration: 130708804, states[0] = -84.159682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 144034317, states[0] = 27.686073, states[40]= 0.000029
Saving checkpoint... 
Iteration: 157374656, states[0] = -84.013214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 170868429, states[0] = -84.152737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 183771346, states[0] = -84.155452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 197025526, states[0] = 30.033927, states[40]= 0.000250
Saving checkpoint... 
Iteration: 210389254, states[0] = -84.031418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 223616802, states[0] = -84.148713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 237320308, states[0] = -83.902129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 250477019, states[0] = -84.107316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 263722174, states[0] = -84.154198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277073228, states[0] = 12.767209, states[40]= 0.000219
Saving checkpoint... 
Iteration: 290300871, states[0] = -83.845730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303603564, states[0] = -84.146146, states[40]= 0.000001
Saving checkpoint... 
Iteration: 317032264, states[0] = 28.324565, states[40]= 0.000038
Saving checkpoint... 
Iteration: 330410481, states[0] = -84.055028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 344213803, states[0] = -83.417179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357701478, states[0] = -84.153190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 371031368, states[0] = 28.580680, states[40]= 0.000046
Saving checkpoint... 
Iteration: 384364708, states[0] = -83.993753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 397874329, states[0] = -84.149444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411151481, states[0] = -44.296293, states[40]= 0.000113
Saving checkpoint... 
Iteration: 424445128, states[0] = -84.085461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 437689573, states[0] = -84.152371, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450516407, states[0] = -84.123970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 463811844, states[0] = -84.151587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476224686, states[0] = -83.490120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490070818, states[0] = 13.802170, states[40]= 0.000190
Saving checkpoint... 
Iteration: 503514389, states[0] = -84.122897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 516608490, states[0] = -84.145540, states[40]= 0.000001
Saving checkpoint... 
Iteration: 530027392, states[0] = 29.618534, states[40]= 0.000136
Saving checkpoint... 
Iteration: 544028572, states[0] = 29.328914, states[40]= 0.000095
Saving checkpoint... 
Iteration: 557449068, states[0] = -84.087589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 570970208, states[0] = -84.143388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 584053513, states[0] = 20.881075, states[40]= 0.000064
Saving checkpoint... 
Iteration: 596371465, states[0] = -84.003317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 609033384, states[0] = 27.995840, states[40]= 0.000032
Saving checkpoint... 
Iteration: 621537531, states[0] = -84.130068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 634059114, states[0] = 18.658934, states[40]= 0.000092
Saving checkpoint... 
Iteration: 646758446, states[0] = -84.151750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 659570071, states[0] = -84.138124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 671841227, states[0] = -84.149291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 685173694, states[0] = -65.632042, states[40]= 0.000005
Saving checkpoint... 
Iteration: 697631501, states[0] = -84.147153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 710966986, states[0] = -84.142750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 724594125, states[0] = -84.142207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738964379, states[0] = -84.142733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753549115, states[0] = -84.132578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 768227183, states[0] = -83.503656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782866335, states[0] = -84.147560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 797237868, states[0] = -83.566391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811890371, states[0] = -84.146247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 826465998, states[0] = -84.097323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 840940104, states[0] = -84.143480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 855087951, states[0] = 6.146413, states[40]= 0.000487
Saving checkpoint... 
Iteration: 869065907, states[0] = 15.874053, states[40]= 0.000141
Saving checkpoint... 
Iteration: 883231561, states[0] = -83.529228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898403949, states[0] = -84.044552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 913668971, states[0] = -84.148697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 928881646, states[0] = -84.145988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944259103, states[0] = -83.677074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959625268, states[0] = -84.144978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 975131240, states[0] = -26.250754, states[40]= 0.000503
Saving checkpoint... 
Iteration: 990691138, states[0] = -84.149190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006150868, states[0] = -43.738806, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1021746719, states[0] = -84.149663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1037382019, states[0] = -84.016228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1052940361, states[0] = -84.142226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1068473170, states[0] = -84.100163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084040217, states[0] = 25.792587, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1099582256, states[0] = -84.137967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1115048006, states[0] = 22.989359, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1130607401, states[0] = -84.141803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146104005, states[0] = -2.610744, states[40]= 0.000864
Saving checkpoint... 
Iteration: 1161607356, states[0] = -84.141615, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1177092052, states[0] = 4.150042, states[40]= 0.000590
Saving checkpoint... 
Iteration: 1192504894, states[0] = -84.115064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1208099488, states[0] = 0.175204, states[40]= 0.000783
Saving checkpoint... 
Iteration: 1223749437, states[0] = -84.148465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1239272274, states[0] = -83.734720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254820223, states[0] = -84.146679, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1270407103, states[0] = -84.045853, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1285991571, states[0] = -84.137991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1301613067, states[0] = -84.141549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1316844247, states[0] = -84.145397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1331710141, states[0] = -84.147665, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344496059, states[0] = -84.110301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358525058, states[0] = -84.121748, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1371626361, states[0] = -84.142687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1382349388, states[0] = -83.960409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1395689464, states[0] = -84.146768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408926993, states[0] = -84.140866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422286486, states[0] = -83.789733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435457152, states[0] = -84.088071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1448824928, states[0] = -84.145376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1461614892, states[0] = -84.140843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474672561, states[0] = -84.145603, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1488136025, states[0] = -30.506777, states[40]= 0.000450
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.012194
 - CaMKt in component CaMK (millimolar): 0.005187
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.327079
 - nass in component intracellular_ions (millimolar): 6.327186
 - ki in component intracellular_ions (millimolar): 145.535114
 - kss in component intracellular_ions (millimolar): 145.535098
 - cansr in component intracellular_ions (millimolar): 1.690447
 - cajsr in component intracellular_ions (millimolar): 1.689767
 - cai in component intracellular_ions (millimolar): 0.000092
 - m in component INa (dimensionless): 0.010827
 - hf in component INa (dimensionless): 0.550609
 - hs in component INa (dimensionless): 0.550615
 - j in component INa (dimensionless): 0.550642
 - hsp in component INa (dimensionless): 0.306714
 - jp in component INa (dimensionless): 0.550656
 - mL in component INaL (dimensionless): 0.000392
 - hL in component INaL (dimensionless): 0.386077
 - hLp in component INaL (dimensionless): 0.208275
 - a in component Ito (dimensionless): 0.001299
 - iF in component Ito (dimensionless): 0.999123
 - iS in component Ito (dimensionless): 0.845857
 - ap in component Ito (dimensionless): 0.000662
 - iFp in component Ito (dimensionless): 0.999123
 - iSp in component Ito (dimensionless): 0.874791
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.973277
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003220
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.210890
 - xs1 in component IKs (dimensionless): 0.133337
 - xs2 in component IKs (dimensionless): 0.000297
 - xk1 in component IK1 (dimensionless): 0.996915
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
17:09:13 (1969): called boinc_finish(0)

</stderr_txt>
]]>


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